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Justin C. Boucher
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Journal Articles

A Novel IL2Rα-/- Model for CAR-T Toxicity in Acute Lymphoblastic Leukemia Recapitulates Cytokine Release Syndrome and Neutropenia

Payal Goala, Hiroshi Kotani, Zhang Yongliang, Kayla M. Reid, Justin C. Boucher, Constanza Savid-Frontera, Sae Bom Lee, Nolan Beatty, Michael D. Jain, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 1176–1177.
https://doi.org/10.1182/blood-2022-165562
Published: 2022
Journal Articles

Bispecific CD33/CD123 Targeted Chimeric Antigen Receptor T Cells for the Treatment of Acute Myeloid Leukemia

Justin C. Boucher, Bishwas Shrestha, Paresh Vishwasrao, Mark B. Leick, Nhan Tu, Tayyebb Ghafoor, Kayla M. Reid, Kristen Spitler, Bin Yu, Marcela V. Maus, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 10275–10276.
https://doi.org/10.1182/blood-2022-163299
Published: 2022
Journal Articles

Large Scale Ex Vivo Expansion of Γδ T Cells Using Artificial Antigen Presenting Cells for the Treatment of Acute Myeloid Leukemia

Justin C. Boucher, PhD, Bin Yu, Gongbo Li, PhD MBBS, Bishwas Shrestha, PhD, Jeffrey E. Lancet, MD, David A. Sallman, MD, Ana Marie Landin, Adam William Mailloux, PhD, Claudio Anasetti, MD, Linda L. Kelley, PhD, Marco L. Davila, MD PhD, Nelli Bejanyan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-136174
Published: 2020
Journal Articles

Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma

Michael D. Jain, MD PhD, Hua Zhao, Reginald Atkins, Meghan A Menges, Crystal R Pope, Rawan Faramand, MD, Sae Bom Lee, Justin C. Boucher, PhD, Hiroshi Kotani, MD PhD, Christina A Bachmeier, PharmD, Julio Chavez, Bijal Shah, MD, Mohammad Hussaini, MD, Ricardo J Gonzalez, MD, John E Mullinax, MD PhD, Marco L. Davila, MD PhD, Frederick L. Locke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2885.
https://doi.org/10.1182/blood-2019-131041
Published: 2019
Journal Articles

Human CD83 Targeted Chimeric Antigen Receptor T Cell for the Prevention of Graft Versus Host Disease and Treatment of Myeloid Leukemia

Bishwas Shrestha, PhD, Kelly Walton, Jordan Reff, Elizabeth M. Sagatys, MD, Nhan Tu, PhD, Justin C. Boucher, PhD, Tayyeb Ghafoor, BS, Joseph Pidala, MD, Bruce R. Blazar, MD, Claudio Anasetti, MD, Brian C. Betts, MD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 196.
https://doi.org/10.1182/blood-2019-124031
Published: 2019
Journal Articles

MDSC Suppression of CAR T Cells Can be Reduced By Targeted Signaling Disruption

Estelle V Cervantes, Justin C. Boucher, PhD, Sae Bom Lee, Kristen Spitler, Kayla Reid, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4438.
https://doi.org/10.1182/blood-2019-122752
Published: 2019
Journal Articles

Mutation of the CD28 Co-Stimulatory Domain Confers Enhanced CAR T Cell Function

Justin C. Boucher, PhD, Gongbo Li, PhD MBBS, Hiroshi Kotani, MD PhD, Maria Cabral, Dylan Morrissey, Sae Bom Lee, Kristen Spitler, Nolan Beatty, Bishwas Shrestha, PhD, Bin Yu, Aslamuzzaman Kazi, Xuefeng Wang, PhD, Said Sebti, PhD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 248.
https://doi.org/10.1182/blood-2019-122954
Published: 2019
Journal Articles

Aged CAR T Cells Exhibit Enhanced Cytotoxicity and Effector Function but Shorter Persistence and Less Memory-like Phenotypes

Hiroshi Kotani, MD PhD, Gongbo Li, PhD MBBS, Jiqiang Yao, PhD, Tania E. Mesa, BS, Jon Chen, PhD, Justin C. Boucher, PhD, Sean J. Yoder, MS, Jing Zhou, MD PhD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2047.
https://doi.org/10.1182/blood-2018-99-115351
Published: 2018
Journal Articles

Mutation of the CD28 Costimulatory Domain Confers Decreased CAR T Cell Exhaustion

Justin C. Boucher, PhD, Gongbo Li, PhD MBBS, Bishwas Shrestha, PhD BS, Maria Cabral, Dylan Morrissey, Lawrence Guan, Marco L. Davila, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 966.
https://doi.org/10.1182/blood-2018-99-110645
Published: 2018
Journal Articles

Next Generation Sequencing of Immunized Mouse Splenocytes to Develop an Anti-TIM3 Chimeric Antigen Receptor for Acute Myeloid Leukemia

Justin C. Boucher, PhD, Paresh Vishwasrao, Lawrence Guan, Bishwas Shrestha, PhD, Gongbo Li, PhD MBBS, Scott Christley, Lindsay G. Cowell, PhD, Jared Ostmeyer, William H. Rounds, Inimary T. Toby, PhD, Marco L. Davila, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2646.
https://doi.org/10.1182/blood.V130.Suppl_1.2646.2646
Published: 2017
Journal Articles

Mouse CD19-Targeted Chimeric Antigen Receptors That Include a 41BB Co-Stimulatory Domain Induce NFkB Signaling to Enhance T Cell Proliferation, Viability, and Leukemia Killing

Gongbo Li, PhD MBBS, Nolan Beatty, Paresh Vishwasrao, Justin C. Boucher, PhD, Bin Yu, Kyungho Park, Yongliang Zhang, PhD BMBS, Marco L. Davila, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 843.
https://doi.org/10.1182/blood.V130.Suppl_1.843.843
Published: 2017