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Journal Articles

HLA-Pan-DP CAR-T Demonstrates Cytotoxicity Against Multiple Hematological Malignancies

Hiroyuki Takamatsu, Emilio Ramos, Bonell Patino-Escobar, Corynn Kasap, Adila Izgutdina, Juwita Werner, Akihito Inagaki, Takeshi Yoroidaka, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Veronica Steri, Elliot Stieglitz, Masaki Nagato, Satoshi Tatsuno, Arun P Wiita

Blood (2024) 144 (Supplement 1): 1038.

https://doi.org/10.1182/blood-2024-193709

Published: 2024

Journal Articles

Structure Guided Design of CCL27 CAR T-Cells Against CCR10 for Multiple Myeloma

Nikhil Chilakapati, Bonell Patino-Escobar, Jonathan deMontagnac, Haley Johnson, Emilio Ramos, Paul Phojanakong, Fernando Salangsang, Veronica Steri, William J Karlon, Arun P Wiita

Blood (2024) 144 (Supplement 1): 2036.

https://doi.org/10.1182/blood-2024-206274

Published: 2024

Journal Articles

CD48: Friend or Foe in NK-Cell Immunosurveillance of Multiple Myeloma?

Bonell Patiño-Escobar, Lucy Perez-Lugo, Huimin Geng, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Veronica Steri, Oscar A Aguilar, Arun P Wiita

Blood (2024) 144 (Supplement 1): 4646.

https://doi.org/10.1182/blood-2024-206465

Published: 2024

Journal Articles

CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition

Timothy T. Ferng, Samantha M. Pintar, Vanessa E. Kennedy, Shaheen Kabir, Theodore C. Tarver, III, Veronica Steri, Paul Phojanakong, Juwita Hübner, Carolina E. Morales, Jose M. Rivera, Aaron C. Logan, Benjamin Braun, Elliot Stieglitz, Luke A. Gilbert, Catherine C. Smith

Blood (2024) 144 (Supplement 1): 723.

https://doi.org/10.1182/blood-2024-204168

Published: 2024

Journal Articles

Discovery and Development of CD70 As a Cellular Therapy Target in High Risk Multiple Myeloma

Blood (2023) 142 (Supplement 1): 465.

https://doi.org/10.1182/blood-2023-182578

Published: 2023

Journal Articles

Mediator Kinase/CDK8 Inhibition As a Strategy to Improve FLT3 Inhibitor Activity in Acute Myeloid Leukemia

Timothy T. Ferng, Samantha M. Pintar, Vanessa E. Kennedy, Theodore C. Tarver, III, Shaheen Kabir, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Juwita Hübner, Carolina E. Morales, Jose M. Rivera, Aaron C. Logan, Benjamin Braun, Elliot Stieglitz, Luke A. Gilbert, Catherine C. Smith

Blood (2023) 142 (Supplement 1): 4173.

https://doi.org/10.1182/blood-2023-180290

Published: 2023

Journal Articles

Affinity Matured CD72 CAR-T Improves Efficacy Versus Low Antigen Density B-Cell Non-Hodgkin Lymphoma Models

Adila Izgutdina, William C Temple, Matthew Andrew Nix, Huimin Geng, Emilio Ramos, Akul Naik, Rebecca Larson, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Ons Zakraoui, Isa Tariq, Marcela V Maus, Veronica Steri, Arun P Wiita

Blood (2023) 142 (Supplement 1): 2068.

https://doi.org/10.1182/blood-2023-182873

Published: 2023

Journal Articles

Humanized Nanobody Anti-CD72 CAR-T Cells Efficiently Eliminate B-Cell Malignancies Via Improved Affinity for CD72 but Induce Persistent Antigen Downregulation In Vivo

William C Temple, Gianina Wicaksono, Akul Naik, Adila Izgutdina, Matthew A Nix, Elizabeth Young, Paul Phojanakong, Juan Antonio Camara Serrano, Veronica Steri, Fernando Salangsang, Arun P Wiita

Blood (2022) 140 (Supplement 1): 7394–7395.

https://doi.org/10.1182/blood-2022-168490

Published: 2022

Journal Articles

Structural Surfaceomics Reveals an AML-Specific Conformation of Integrin-β2 As an Immunotherapeutic Target

Blood (2022) 140 (Supplement 1): 867–868.

https://doi.org/10.1182/blood-2022-162697

Published: 2022

Journal Articles

CD72 Nanobody-Based CAR-T Cells Have Potent Anti-Tumor Efficacy in B Cell Malignancies

Matthew A Nix, William C Temple, William Karlon, Donghui Wang, Paul Phojanakong, Veronica Steri, Byron Hann, Arun P Wiita

Blood (2021) 138 (Supplement 1): 1717.

https://doi.org/10.1182/blood-2021-153935

Published: 2021

Journal Articles

Functional Multi-Omics Reveals Genetic and Pharmacologic Regulation of Surface CD38 in Multiple Myeloma

Priya Choudhry, Olivia Gugliemini, Huimin Geng, Vishesh Sarin, Letitia Sarah, Yu-Hsiu T. Lin, Neha Paranjape, Poornima Ramkumar, Makeba Marcoulis, Donghui Wang, Paul Phojanakong, Veronica Steri, Byron Hann, Martin Kampmann, Arun P Wiita

Blood (2021) 138 (Supplement 1): 2648.

https://doi.org/10.1182/blood-2021-147007

Published: 2021

Journal Articles

Allosteric SHP2 Inhibitor RMC4550 Synergizes with Venetoclax in FLT3 and KIT Mutant Acute Myeloid Leukemia

Bogdan Popescu, Carlos Stahlhut, Theodore C. Tarver, III, Timothy T. Ferng, Cheryl Peretz, Sydney Wishner, Paul Phojanakong, Veronica Steri, Eric B. Wong, Jose M. Rivera, Elliot Stieglitz, Catherine C. Smith

Blood (2021) 138 (Supplement 1): 2231.

https://doi.org/10.1182/blood-2021-145964

Published: 2021

Journal Articles

In Vitro -Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies

Matthew Nix, PhD, Yu-Hsiu T. Lin, BA, Huimin Geng, PhD, Makeba Marcoulis, BA, Paul Phojanakong, BA, Donghui Wang, BA, Veronica Steri, PhD, Jeffrey Whitman, MD, Sagar Bapat, MD PhD, Elliot Stieglitz, MD, Anne Deucher, MD PhD, Kristie L White, MD MD, Byron C Hann, MD PhD, Arun P. Wiita, MD PhD

Blood (2019) 134 (Supplement_1): 1337.

https://doi.org/10.1182/blood-2019-130938

Published: 2019

Journal Articles

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

Ian Ferguson, BA, Christine Lam, BA, Margarette C. Mariano, MS, Donghui Wang, BA, Paul Phojanakong, BA, Sami Toumivaara, PhD, Hao Shao, PhD, Byron C Hann, MD PhD, Jason Gestwicki, PhD, Arun P Wiita, MDPhD

Blood (2018) 132 (Supplement 1): 3212.

https://doi.org/10.1182/blood-2018-99-117401

Published: 2018

NARROW

HLA-Pan-DP CAR-T Demonstrates Cytotoxicity Against Multiple Hematological Malignancies

Structure Guided Design of CCL27 CAR T-Cells Against CCR10 for Multiple Myeloma

CD48: Friend or Foe in NK-Cell Immunosurveillance of Multiple Myeloma?

CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition

Discovery and Development of CD70 As a Cellular Therapy Target in High Risk Multiple Myeloma

Mediator Kinase/CDK8 Inhibition As a Strategy to Improve FLT3 Inhibitor Activity in Acute Myeloid Leukemia

Affinity Matured CD72 CAR-T Improves Efficacy Versus Low Antigen Density B-Cell Non-Hodgkin Lymphoma Models

Humanized Nanobody Anti-CD72 CAR-T Cells Efficiently Eliminate B-Cell Malignancies Via Improved Affinity for CD72 but Induce Persistent Antigen Downregulation In Vivo

Structural Surfaceomics Reveals an AML-Specific Conformation of Integrin-β2 As an Immunotherapeutic Target

CD72 Nanobody-Based CAR-T Cells Have Potent Anti-Tumor Efficacy in B Cell Malignancies

Functional Multi-Omics Reveals Genetic and Pharmacologic Regulation of Surface CD38 in Multiple Myeloma

Allosteric SHP2 Inhibitor RMC4550 Synergizes with Venetoclax in FLT3 and KIT Mutant Acute Myeloid Leukemia

In Vitro -Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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