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Carolina E. Morales
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Journal Articles

Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AML

Open Access
Bogdan Popescu, Matthew F Jones, Madison Piao, Elaine Tran, Andrew Koh, Isabelle Lomeli, Cheryl A. C. Peretz, Natalia Murad, Sydney Abelson, Carolina E. Morales, Jose M Rivera, Alexa Rane Batingana, Jeevitha D'Souza, Yana Pikman, Michael L. Cheng, Aaron C Logan, Benjamin J. Huang, Elliot Stieglitz, Catherine C. Smith
Journal: Blood
Blood blood.2025030558.
https://doi.org/10.1182/blood.2025030558
Published: 2025
Includes: Supplemental data
Journal Articles

CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition

Free
Timothy T. Ferng, Samantha M. Pintar, Vanessa E. Kennedy, Shaheen Kabir, Theodore C. Tarver, III, Veronica Steri, Paul Phojanakong, Juwita Hübner, Carolina E. Morales, Jose M. Rivera, Aaron C. Logan, Benjamin Braun, Elliot Stieglitz, Luke A. Gilbert, Catherine C. Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 723.
https://doi.org/10.1182/blood-2024-204168
Published: 2024
Journal Articles

Preclinical Activity of RAS(ON) Multi-Selective Inhibitor RMC-7977 and Therapeutic Combinations in AML with Signaling Mutations

Free
Bogdan Popescu, Madison Piao, Sydney Abelson, Carolina E. Morales, Khadija Yousuf, Jose M. Rivera, Cheryl A C Peretz, Elliot Stieglitz, Catherine C. Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2024-208386
Published: 2024
Journal Articles

Mediator Kinase/CDK8 Inhibition As a Strategy to Improve FLT3 Inhibitor Activity in Acute Myeloid Leukemia

Free
Timothy T. Ferng, Samantha M. Pintar, Vanessa E. Kennedy, Theodore C. Tarver, III, Shaheen Kabir, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Juwita Hübner, Carolina E. Morales, Jose M. Rivera, Aaron C. Logan, Benjamin Braun, Elliot Stieglitz, Luke A. Gilbert, Catherine C. Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4173.
https://doi.org/10.1182/blood-2023-180290
Published: 2023