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Journal Articles

Pooled Efficacy and Safety of Teclistamab in 217 Patients with Triple-Class Exposed Relapsed/Refractory Multiple Myeloma from 3 Registrational Clinical Studies

Thomas G Martin, María-Victoria Mateos, Niels W.C.J. van de Donk, Zhen Cai, Weijun Fu, Alfred L Garfall, Shinsuke Iida, Yoshiaki Kuroda, Ting Niu, Ajay K. Nooka, Surbhi Sidana, Katherine Chastain, Margaret Doyle, Kazuko Nishikawa, Yang Song, Hiroshi Yamazaki, Jianmin Zhuo, Yan Zhu, Juan Du, Tadao Ishida
Journal: Blood
Blood (2024) 144 (Supplement 1): 3331.
https://doi.org/10.1182/blood-2024-200354
Published: 2024
Journal Articles

Zanubrutinib Combined with R-CHOP in Previously Untreated Non-Germinal Center B-Cell (GCB) Diffuse Large B-Cell Lymphoma (DLBCL) Patients with BCL2 and MYC Protein Co-Expression: A Multicenter, Phase II Study

Jia Jin, Yalan Wang, Xi Wang, Yonghong Tang, Shan Zeng, Juan Du, Junning Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 3116.
https://doi.org/10.1182/blood-2024-200585
Published: 2024
Journal Articles

Comparative Effectiveness of Linvoseltamab Versus Current Real-World Standard of Care Therapies in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma Treated at IMWG Sites

Shaji Kumar, Sundar Jagannath, Katja C. Weisel, Laura Rosiñol Dachs, Meletios-Athanasios Dimopoulos, David S. Siegel, Jorge Monge, Xavier Leleu, Juan Du, Javier de la Rubia, Jae Hoon Lee, María-Victoria Mateos, Alessandro Gozzetti, Dominik Dytfeld, Enrique M. Ocio, Joan Bladé, Shuji Ozaki, Madhu Nagaraj, Rafla Hassan, Jeannette Green, Glenn S. Kroog, Karen Rodriguez Lorenc, Christian Hampp, Qiufei Ma, Brian G.M. Durie
Journal: Blood
Blood (2024) 144 (Supplement 1): 7039.
https://doi.org/10.1182/blood-2024-210376
Published: 2024
Journal Articles

GPRC5D-Targeted CAR T-Cell Therapy CT071 for the Treatment of Refractory/Relapsed Multiple Myeloma

Juan Du, Lina Jin, Sinan Gu, Jing Lu, Haiyan He, Qianqi Ruan, Wanting Qiang, Xiaoqiang Fan, Jin Liu, Xingxing Meng, Nishanthan Rajakumaraswamy, Deng Chen, Zonghai Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 3451.
https://doi.org/10.1182/blood-2024-204790
Published: 2024
Journal Articles

Comparative Effectiveness of Linvoseltamab Versus Current Real-World (RW) Standard-of-Care (SOC) Therapies in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma (RRMM): Key Subgroups Analysis

Shaji Kumar, Sundar Jagannath, Katja C. Weisel, Laura Rosiñol Dachs, Meletios-Athanasios Dimopoulos, David S. Siegel, Jorge Monge, Xavier Leleu, Juan Du, Javier de la Rubia, Jae Hoon Lee, María-Victoria Mateos, Borja Puertas Martínez, Alessandro Gozzetti, Dominik Dytfeld, Enrique M. Ocio, Joan Bladé, Shuji Ozaki, Meral Beksac, Fernando Escalante, Madhu Nagaraj, Rafla Hassan, Paul Spin, Nicolle Bonar, Mostafa Shokoohi, Muhaimen Siddiqui, Di Wang, Kevin Hou, Jeannette Green, Olivier Humblet, Alexander Breskin, James Harnett, Wenzhen Ge, Rachel E. Sobel, Jessica J. Jalbert, Glenn S. Kroog, Karen Rodriguez Lorenc, Qiufei Ma, Christian Hampp, Brian G.M. Durie
Journal: Blood
Blood (2024) 144 (Supplement 1): 7012.
https://doi.org/10.1182/blood-2024-200679
Published: 2024
Journal Articles

High Risk Cytogenetic Abnormalities Are Poor Prognostic Factors for Newly Diagnosed Multiple Myeloma Patients Received Autologous Hematopoietic Cell Transplantation

Chuanying Geng, Jing Lu, Xiaozhe Li, Qiang Li, Na Li, Weiwei Tian, Jie Zhao, Guangzhong Yang, Yanping Ma, Xiaoqi Qin, Jing Jia, Huixing Zhou, Lintao Bi, Chenchen Wang, Ying Sun, Xiantao Liu, Yuan Jian, Qingming Wang, Haixiang Wan, Jinqiao Zhang, Han Liu, Hui Geng, Xiaojing Ma, Yunxia Liang, Rui Hu, Da Gao, Donghai Han, Haisheng Liu, Guangyu Ma, Zhihua Zhang, Wei Wang, Shi Minxia, Bo Nie, Zhang Hong, Jie Li, Guitao Jie, Meiying Fan, Qinglin Song, Wenyong Li, Zhenfang Xi, Guorong Gao, Jie Liu, Zhihua Li, Hua Xue, Huimei Guo, Jie Li, Xiaohan Gao, Guo-Hong Su, Jie Shen, ARong Jin, Peng Lv, Wenming Chen, Juan Li, Juan Du, Wen Gao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6925.
https://doi.org/10.1182/blood-2024-205155
Published: 2024
Journal Articles

Autologous B Cell Maturation Antigen (BCMA) and CD19 Dual Targeting Fastcar-T Cells (GC012F/AZD0120) As First-Line Therapy for Elderly Patients with Newly Diagnosed Multiple Myeloma Patients

Juan Du, Wanting Qiang, Jing Lu, Yanchun Jia, Haiyan He, Jin Liu, Pei Guo, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Nina Shah, Qi Zhang, Jia Liu, Lihong Weng, Lianjun Shen, Wei Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 2072.
https://doi.org/10.1182/blood-2024-204774
Published: 2024
Journal Articles

Optimal Timing and Impact of Allogeneic Peripheral Blood Stem Cell Transplantation in Adult T-Cell Lymphoblastic Lymphoma: Insights from a Large Cohort Multi-Center Real-World Study in Shanghai

Fangfang Yu, Jiahua Niu, Jianmin Yang, Jian Hou, Siguo Hao, Aibin Liang, Hong Xiong, Qi Zhu, Ligen Liu, Jun Shi, Juan Du, Bobin Chen, Rong Wei, Wenli Zhao, Lihua Sun, Yunhua Hou, Rong Tao, Xianmin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 7818.
https://doi.org/10.1182/blood-2024-199964
Published: 2024
Journal Articles

Updated Results of a Phase I Open-Label Single-Arm Study of Dual Targeting BCMA and CD19 Fastcar-T Cells (GC012F) As First-Line Therapy for Transplant-Eligible Newly Diagnosed High-Risk Multiple Myeloma

Juan Du, Wanting Qiang, Jing Lu, Yanchun Jia, Haiyan He, Jin Liu, Pei Guo, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Jia Liu, Qi Zhang, Lianjun Shen, Lihong Weng, Wenling Li, Wei Cao
Journal: Blood
Blood (2023) 142 (Supplement 1): 1022.
https://doi.org/10.1182/blood-2023-174841
Published: 2023
Journal Articles

Identification of LPAR1/LPAR5 As Novel GPCR Partners of GPRC5D for the Efficient CAR-T Therapy of Multiple Myeloma

Xinyi Zhou, Ying Yang, Xiaoli Hu, Tiancheng Luo, Shangrun Liu, Chao Zhang, Juan Du
Journal: Blood
Blood (2023) 142 (Supplement 1): 4679.
https://doi.org/10.1182/blood-2023-186150
Published: 2023
Journal Articles

Zanubrutinib Combined with R-CHOP in Previously Untreated Non-Germinal Center B-Cell (GCB) Diffuse Large B-Cell Lymphoma (DLBCL) Patients with BCL2 and MYC Protein Co-Expression: A Multicenter, Phase II Study

Jia Jin, Yalan Wang, Xi Wang, Yonghong Tang, Shan Zeng, Juan Du, Junning Cao
Journal: Blood
Blood (2023) 142 (Supplement 1): 4468.
https://doi.org/10.1182/blood-2023-181529
Published: 2023
Journal Articles

PET Tracer-Based Glucose Uptake Predicts Clinical Response to Induction Therapy in Acute Myeloid Leukaemia

Hui Zeng, Suqi Deng, Juan Du, Huien Zhan, Kexiu Huang, Xue Zheng, Ying Xu, Lu Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1592.
https://doi.org/10.1182/blood-2023-189148
Published: 2023
Journal Articles

Ixazomib Maintenance Therapy in Chinese Patients with Newly Diagnosed Multiple Myeloma Not Treated with Stem Cell Transplantation: A Single-Arm, Open-Label Study

Weijun Fu, Juan Du, Lu Zhong, Lijuan Chen, Jian Li, Donghua Zhang, Jianqing Mi, Yan Liu, Sheng Wu, Richard Labotka, Cong Li, Wenhan Jiang, Wenming Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6735.
https://doi.org/10.1182/blood-2023-181444
Published: 2023
Journal Articles

Oligosecretory Waldenström Macroglobulinemia Patients Exhibit Excellent Treatment Response and Outcomes

Ying Yu, Wenjie Xiong, Zanzan Wang, Yuting Yan, Jiawen Chen, Yanshan Huang, Xinxin Cao, Zhongxing Jiang, Huihan Wang, Zhen Cai, Juan Du, Chunyan Sun, Ting Niu, Guangzhong Yang, Hua Xue, Bingzong Li, Honghui Huang, Zhenling Li, Qinhua Liu, Fei Li, Ou Bai, Min Mao, Rong Fu, Ling Wang, Chunrui Li, Xiaoxia Chu, Lihong Liu, Yujun Dong, Luqun Wang, Jun Luo, Yongqiang Wei, Lugui Qiu, Jian Li, ShuHua Yi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9289–9291.
https://doi.org/10.1182/blood-2022-157311
Published: 2022
Journal Articles

Hyperglycemia Induces Endothelial Dysfunction through Hedgehog Signaling-Mediated TNF-α Production

Hui Zeng, Shurong Xie, Heng Wan, Heng Meng, Bo Hu, Juan Du
Journal: Blood
Blood (2022) 140 (Supplement 1): 2667–2668.
https://doi.org/10.1182/blood-2022-163132
Published: 2022
Journal Articles

Phase I Open-Label Single-Arm Study of BCMA/CD19 Dual-Targeting FasTCAR-T Cells (GC012F) As First-Line Therapy for Transplant-Eligible Newly Diagnosed High-Risk Multiple Myeloma

Juan Du, Weijun Fu, Jing Lu, Wanting Qiang, Haiyan He, Jin Liu, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Jia Liu, Qi Zhang, Lianjun Shen, Lihong Weng, Wei Cao
Journal: Blood
Blood (2022) 140 (Supplement 1): 889–890.
https://doi.org/10.1182/blood-2022-162295
Published: 2022
Journal Articles

Hexamethylene Amiloride Sensitizes AML to Venetoclax through Inducing Lysosomal Membrane Permeabilization

Hui Zeng, Xinya Jiang, Juan Du, Lei Hua, Xiaofan Sun, Fangshu Liu
Journal: Blood
Blood (2022) 140 (Supplement 1): 8797–8798.
https://doi.org/10.1182/blood-2022-164960
Published: 2022
Journal Articles

Real-World Effectiveness of Bortezomib Plus Dexamethasone in Patients with t(11;14) Positive Multiple Myeloma

Nnadozie Emechebe, Shaji Kumar, Hartmut Goldschmidt, Maria-Victoria Mateos, Juan Du, Kihyun Kim, Giampaolo Merlini, Meletios A. Dimopoulos, Heinz Ludwig, Hiroshi Handa, Carlos Fernandez de Larrea, Donna E. Reece, Wenming Chen, Noopur S. Raje, Sudeep Karve, Emma Arriola, Jeremy A. Ross, Brian G.M. Durie
Journal: Blood
Blood (2021) 138 (Supplement 1): 4725.
https://doi.org/10.1182/blood-2021-149270
Published: 2021
Journal Articles

Targeting PRMT9 Suppresses Acute Myeloid Leukemia Maintenance

Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yuhui Wu, Yinghui Zhu, Hanying Wang, Wenfeng Huang, Yichun Lin, Lianjun Zhang, Dandan Zhao, Juan Du, Rui Su, Ya-Huei Kuo, Jianjun Chen, Amandeep Salhotra, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 358.
https://doi.org/10.1182/blood-2021-151679
Published: 2021
Journal Articles

Clinical Results of a Multicenter Study of the First-in-Human Dual BCMA and CD19 Targeted Novel Platform Fast CAR-T Cell Therapy for Patients with Relapsed/Refractory Multiple Myeloma

Hua Jiang, MD, Baoxia Dong, MD PhD, Li Gao, Li Liu, MD, Jian Ge, Aili He, Juan Du, Jr., MD, Lu Li, Jing Lu, MD, Xiequn Chen, Yi Zhao, Yu Han, Yuezhang Chen, Yuesheng Xu, Hua Zhang, Jiaping He, Huan Shi, Cong Han, Xun Ye, Zhenguang Wang, Jia Liu, Lianjun Shen, MD, Wei Cao, Martina Sersch, MD PhD, Weijun Fu, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-138614
Published: 2020