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Journal Articles

Updated results of a first-in-human, Phase Ⅰa/Ⅰb study of QLS32015 (GPRC5D×CD3) in patients (pts) with relapsed/refractory multiple myeloma (RRMM)

Gang An, Baijun Fang, Xiaobing Huang, Yan Xu, Fei Li, Zhen Cai, Xiaojing Yan, Xianqi Feng, Wuping Li, Xiangmin Tong, Zengjun Li, Yuzhang Liu, Feifei Che, Xin'ai Yang, Xianlin Duan, Peng Shao, Xiaoyan Kang, Lugui Qiu

Blood (2025) 146 (Supplement 1): 4049.

https://doi.org/10.1182/blood-2025-4049

Published: 2025

Journal Articles

Super-enhancer-mediated regulation of CD38 inducibility in multiple myeloma via the MAF/TRIM47/RARα axis

Zhenfeng Dai, Yunlu Jia, Qiqi Shen, Haoguang Chen, Xinyuan Dai, Shengchun Jin, Enfan Zhang, Jianbiao Zhou, Gang Xiao, Wee-joo Chng, Zhen Cai

Blood (2025) 146 (Supplement 1): 2156.

https://doi.org/10.1182/blood-2025-2156

Published: 2025

Journal Articles

Teclistamab in a large cohort of ~100 Asian patients with triple-class exposed multiple myeloma: Experience from trials and non-trial settings

Blood (2025) 146 (Supplement 1): 5815.

https://doi.org/10.1182/blood-2025-5815

Published: 2025

Journal Articles

Disrupting monocytic AML and monocytic leukemia stem cells with a novel cladribine regimen: From bench to bedside

Jia Hu, Jingyi Huang, Wei Bian, Xiaoqing Zou, Yuanyuan Zhu, Weijia Huang, Yue Liang, Yi Zhao, Weiyan Zheng, Lixia Zhu, Xiu-Jin Ye, Yi Luo, Jimin Shi, Zhen Cai, He Huang, Shanshan Pei, Jie Sun

Blood (2025) 146 (Supplement 1): 1508.

https://doi.org/10.1182/blood-2025-1508

Published: 2025

Journal Articles

The addition of EBV and C3 complement risk factors formed a better angioimmunoblastic T-cell lymphoma prognostic scoring system

Mengmeng Dong, Yi Zhong, Fang Yu, Yi Zhao, Lixia Zhu, Fengping Zhou, Linlin Huang, Xiu-Jin Ye, Zhen Cai, He Huang, Jin Zhang, Baodong Ye, Qingming Wang, Jingsong He

Blood (2025) 146 (Supplement 1): 7148.

https://doi.org/10.1182/blood-2025-7148

Published: 2025

Journal Articles

High serum C3 complement levels were associated with poor prognosis of angioimmunoblastic T-cell lymphoma (AITL)

Mengmeng Dong, Yi Zhong, Fang Yu, Yi Zhao, Lixia Zhu, Fengping Zhou, Linlin Huang, Xiu-Jin Ye, Zhen Cai, He Huang, Jin Zhang, Baodong Ye, Qingming Wang, Jingsong He

Blood (2025) 146 (Supplement 1): 7158.

https://doi.org/10.1182/blood-2025-7158

Published: 2025

Journal Articles

Adult hemophagocytic lymphohistiocytosis: A multicenter retrospective analysis of etiology and impact on survival in China

Jingsong He, Lixia Zhu, Mengqi Xiong, Jianguo Zhang, Yinyi Zhang, Xin Guo, Linjie Li, Lihong Shou, Qunyi Guo, Shuangwei Ying, Li Li, YI LI, Zhen Cai, He Huang, Xiu-Jin Ye

Blood (2025) 146 (Supplement 1): 6549.

https://doi.org/10.1182/blood-2025-6549

Published: 2025

Journal Articles

Prognostic significance of 1q21 gain/amplification and co-existing cytogenetic abnormalities in Chinese patients with newly diagnosed multiple myeloma

Xinyuan Dai, YI LI, Gaofeng Zheng, Xiaoyan Han, Minlei Zhao, Yang Yang, Donghua He, Li Yang, Dan Cao, Lihong Shou, Linjie Li, Haowen Xiao, Wenjun Wu, Yi Zhao, Zhen Cai, Jingsong He

Blood (2025) 146 (Supplement 1): 2242.

https://doi.org/10.1182/blood-2025-2242

Published: 2025

Journal Articles

The m5C-binding protein YB-1 modulates proteasome inhibitors resistance in multiple myeloma via epigenetic modification

Qiqi Shen, Xi Huang, Shunnan Yao, Enfan Zhang, Zhen Cai

Blood (2025) 146 (Supplement 1): 5700.

https://doi.org/10.1182/blood-2025-5700

Published: 2025

Journal Articles

Targeting CCR7 ubiquitination to disrupt protumoral macrophages: A NEDD4-1-dependent strategy to reverse bortezomib resistance in myeloma

Xi Huang, Shunnan Yao, Enfan Zhang, Zhen Cai

Blood (2025) 146 (Supplement 1): 5719.

https://doi.org/10.1182/blood-2025-5719

Published: 2025

Journal Articles

NAMPT in macrophages promotes multiple myeloma drug resistance through mitochondrial metabolic reprogramming and modulates immunosuppression via the SIRT1/STAT3/SPP1 axis.

Shunnan Yao, Gang Xiao, Xi Huang, Qiqi Shen, Haoguang Chen, Chunting Zhu, Shengchun Jin, Enfan Zhang, Zhen Cai

Blood (2025) 146 (Supplement 1): 5707.

https://doi.org/10.1182/blood-2025-5707

Published: 2025

Journal Articles

Characteristics of immune genes rearrangements in Chinese multiple myeloma patients

Donghua He, Yang Yang, Yiwei Zhou, Enfan Zhang, Li Yang, Xiaoyan Han, Jingsong He, Zhen Cai

Blood (2025) 146 (Supplement 1): 5759.

https://doi.org/10.1182/blood-2025-5759

Published: 2025

Journal Articles

Elevated interleukin-10 at diagnosis and during treatment independently predicts adverse outcomes in angioimmunoblastic T-cell lymphoma

Yi Zhong, Mengmeng Dong, Fang Yu, Yi Zhao, Lixia Zhu, Fengping Zhou, Wenjun Wu, Yi Li, Fangshu Guan, Linlin Huang, Xiu-Jin Ye, Zhen Cai, Jin Zhang, Baodong Ye, Qingming Wang, Jingsong He

Blood (2025) 146 (Supplement 1): 3645.

https://doi.org/10.1182/blood-2025-3645

Published: 2025

Journal Articles

Aponermin combined with carfilzomid-pomalidomide-dexamethasone (KPd) in patients with relapsed or refractory multiple myeloma: A prospective, open-label, multicenter study

Jing Chen, Donghua He, Xiaoyan Han, Mingming Zhang, Li Yang, Haimeng Yan, Lai Jin, He Huang, Juan Du, Aijun Liu, Zhen Cai

Blood (2025) 146 (Supplement 1): 2276.

https://doi.org/10.1182/blood-2025-2276

Published: 2025

Journal Articles

Targeted capture sequencing identifies driver mutations and enables prognostic modeling in multiple myeloma

Yang Yang, Donghua He, Jingsong He, Jie Zhang, Yang Nie, Ying Kong, He Huang, Zhen Cai

Blood (2025) 146 (Supplement 1): 5778.

https://doi.org/10.1182/blood-2025-5778

Published: 2025

Journal Articles

Survival outcomes and treatment patterns in primary and secondary plasma cell leukemia: A multicenter retrospective cohort study

Chenyun Wang, Jinuo Wang, Jiahe Li, Donghua He, Xiaoyan Han, Wenjun Wu, Zhen Cai

Blood (2025) 146 (Supplement 1): 4023.

https://doi.org/10.1182/blood-2025-4023

Published: 2025

Journal Articles

Baseline [18F] FDG PET biomarkers of host and tumor predict efficacy and CRS in multiple myeloma patients treated with CAR-T cell therapy

Jing Chen, Song Xue, Xiang Li, marcus hacker, Guilan Hu, Mingming Zhang, He Huang, Zhen Cai

Blood (2025) 146 (Supplement 1): 4018.

https://doi.org/10.1182/blood-2025-4018

Published: 2025

Journal Articles

Deciphering the cellular hierarchy of multiple myeloma uncovers a therapeutically exploitable EP300/TBX2 axis in LILRB4+ myeloma-initiating cells

Haoguang Chen, Shanshan Pei, Qiqi Shen, Zhenfeng Dai, Shunnan Yao, Enfan Zhang, Zhen Cai

Blood (2025) 146 (Supplement 1): 2170.

https://doi.org/10.1182/blood-2025-2170

Published: 2025

Journal Articles

Involvement of bone marrow, liver, spleen and extranodal number were associated with poor outcome in angioimmunoblastic T-cell lymphoma (AITL) patients

Mengmeng Dong, Yi Zhong, Fang Yu, Yi Zhao, Lixia Zhu, Fengping Zhou, Linlin Huang, Xiu-Jin Ye, Zhen Cai, He Huang, Jin Zhang, Baodong Ye, Qingming Wang, Jingsong He

Blood (2025) 146 (Supplement 1): 7169.

https://doi.org/10.1182/blood-2025-7169

Published: 2025

Journal Articles

Myeloma-Associated Macrophages Protect Tumor Cells By Reprogramming of Lipid Metabolism through SREBP1

Xing Guo, Zhenfeng Dai, Enfan Zhang, Zhen Cai

Blood (2024) 144 (Supplement 1): 6858.

https://doi.org/10.1182/blood-2024-210568

Published: 2024

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Updated results of a first-in-human, Phase Ⅰa/Ⅰb study of QLS32015 (GPRC5D×CD3) in patients (pts) with relapsed/refractory multiple myeloma (RRMM)

Super-enhancer-mediated regulation of CD38 inducibility in multiple myeloma via the MAF/TRIM47/RARα axis

Teclistamab in a large cohort of ~100 Asian patients with triple-class exposed multiple myeloma: Experience from trials and non-trial settings

Disrupting monocytic AML and monocytic leukemia stem cells with a novel cladribine regimen: From bench to bedside

The addition of EBV and C3 complement risk factors formed a better angioimmunoblastic T-cell lymphoma prognostic scoring system

High serum C3 complement levels were associated with poor prognosis of angioimmunoblastic T-cell lymphoma (AITL)

Adult hemophagocytic lymphohistiocytosis: A multicenter retrospective analysis of etiology and impact on survival in China

Prognostic significance of 1q21 gain/amplification and co-existing cytogenetic abnormalities in Chinese patients with newly diagnosed multiple myeloma

The m5C-binding protein YB-1 modulates proteasome inhibitors resistance in multiple myeloma via epigenetic modification

Targeting CCR7 ubiquitination to disrupt protumoral macrophages: A NEDD4-1-dependent strategy to reverse bortezomib resistance in myeloma

NAMPT in macrophages promotes multiple myeloma drug resistance through mitochondrial metabolic reprogramming and modulates immunosuppression via the SIRT1/STAT3/SPP1 axis.

Characteristics of immune genes rearrangements in Chinese multiple myeloma patients

Elevated interleukin-10 at diagnosis and during treatment independently predicts adverse outcomes in angioimmunoblastic T-cell lymphoma

Aponermin combined with carfilzomid-pomalidomide-dexamethasone (KPd) in patients with relapsed or refractory multiple myeloma: A prospective, open-label, multicenter study

Targeted capture sequencing identifies driver mutations and enables prognostic modeling in multiple myeloma

Survival outcomes and treatment patterns in primary and secondary plasma cell leukemia: A multicenter retrospective cohort study

Baseline [18F] FDG PET biomarkers of host and tumor predict efficacy and CRS in multiple myeloma patients treated with CAR-T cell therapy

Deciphering the cellular hierarchy of multiple myeloma uncovers a therapeutically exploitable EP300/TBX2 axis in LILRB4+ myeloma-initiating cells

Involvement of bone marrow, liver, spleen and extranodal number were associated with poor outcome in angioimmunoblastic T-cell lymphoma (AITL) patients

Myeloma-Associated Macrophages Protect Tumor Cells By Reprogramming of Lipid Metabolism through SREBP1

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