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Journal Articles

Venetoclax and Decitabine Compared with Standard Intensive Chemotherapy As Induction Therapy in Newly Diagnosed Acute Myeloid Leukemia: Updated Results of a Multicenter, Randomized, Phase 2b Trial

Jing Lu, Shengli Xue, Ying Wang, Xuefeng He, Xiaohui Hu, Miao Miao, Yang Zhang, Zaixiang Tang, Jundan Xie, Xiaofei Yang, Mingzhu Xu, Yaoyao Shen, Feng Du, Qian Vicky Wu, Mengxing Xue, Yun Wang, Ailing Deng, Xueqing Dou, Haiping Dai, Depei Wu, Suning Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 971.
https://doi.org/10.1182/blood-2024-202801
Published: 2024
Journal Articles

Autologous B Cell Maturation Antigen (BCMA) and CD19 Dual Targeting Fastcar-T Cells (GC012F/AZD0120) As First-Line Therapy for Elderly Patients with Newly Diagnosed Multiple Myeloma Patients

Juan Du, Wanting Qiang, Jing Lu, Yanchun Jia, Haiyan He, Jin Liu, Pei Guo, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Nina Shah, Qi Zhang, Jia Liu, Lihong Weng, Lianjun Shen, Wei Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 2072.
https://doi.org/10.1182/blood-2024-204774
Published: 2024
Journal Articles

GPRC5D-Targeted CAR T-Cell Therapy CT071 for the Treatment of Refractory/Relapsed Multiple Myeloma

Juan Du, Lina Jin, Sinan Gu, Jing Lu, Haiyan He, Qianqi Ruan, Wanting Qiang, Xiaoqiang Fan, Jin Liu, Xingxing Meng, Nishanthan Rajakumaraswamy, Deng Chen, Zonghai Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 3451.
https://doi.org/10.1182/blood-2024-204790
Published: 2024
Journal Articles

High Risk Cytogenetic Abnormalities Are Poor Prognostic Factors for Newly Diagnosed Multiple Myeloma Patients Received Autologous Hematopoietic Cell Transplantation

Chuanying Geng, Jing Lu, Xiaozhe Li, Qiang Li, Na Li, Weiwei Tian, Jie Zhao, Guangzhong Yang, Yanping Ma, Xiaoqi Qin, Jing Jia, Huixing Zhou, Lintao Bi, Chenchen Wang, Ying Sun, Xiantao Liu, Yuan Jian, Qingming Wang, Haixiang Wan, Jinqiao Zhang, Han Liu, Hui Geng, Xiaojing Ma, Yunxia Liang, Rui Hu, Da Gao, Donghai Han, Haisheng Liu, Guangyu Ma, Zhihua Zhang, Wei Wang, Shi Minxia, Bo Nie, Zhang Hong, Jie Li, Guitao Jie, Meiying Fan, Qinglin Song, Wenyong Li, Zhenfang Xi, Guorong Gao, Jie Liu, Zhihua Li, Hua Xue, Huimei Guo, Jie Li, Xiaohan Gao, Guo-Hong Su, Jie Shen, ARong Jin, Peng Lv, Wenming Chen, Juan Li, Juan Du, Wen Gao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6925.
https://doi.org/10.1182/blood-2024-205155
Published: 2024
Journal Articles

Updated Results of a Phase I Open-Label Single-Arm Study of Dual Targeting BCMA and CD19 Fastcar-T Cells (GC012F) As First-Line Therapy for Transplant-Eligible Newly Diagnosed High-Risk Multiple Myeloma

Juan Du, Wanting Qiang, Jing Lu, Yanchun Jia, Haiyan He, Jin Liu, Pei Guo, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Jia Liu, Qi Zhang, Lianjun Shen, Lihong Weng, Wenling Li, Wei Cao
Journal: Blood
Blood (2023) 142 (Supplement 1): 1022.
https://doi.org/10.1182/blood-2023-174841
Published: 2023
Journal Articles

Reduced-Dose Chemotherapy Followed By Blinatumomab As Induction Therapy in Treatment of Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Precursor Acute Lymphoblastic Leukemia - Interim Results from a Multicenter, Single-Arm, Phase 2 Study

Jing Lu, Ying Wang, Huiying Qiu, Xin Zhou, Xuzhang Lu, Miao Miao, Bin Gu, Xiaohui Hu, Depei Wu, Suning Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4243.
https://doi.org/10.1182/blood-2023-174831
Published: 2023
Journal Articles

Comparing the Efficacy and Safety of Venetoclax Combined with Decitabine Versus Conventional Chemotherapy As Induction Therapy for Young Adults with Newly Diagnosed Acute Myeloid Leukemia - Interim Analysis of a Multicenter, Randomized, Phase 2b Trial

Jing Lu, Shengli Xue, Ying Wang, Hai-Ping Dai, Xuefeng He, Xiaohui Hu, Miao Miao, Huiying Qiu, Han Yue, Caixia Li, Depei Wu, Suning Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 970.
https://doi.org/10.1182/blood-2023-181347
Published: 2023
Journal Articles

Phase I Open-Label Single-Arm Study of BCMA/CD19 Dual-Targeting FasTCAR-T Cells (GC012F) As First-Line Therapy for Transplant-Eligible Newly Diagnosed High-Risk Multiple Myeloma

Juan Du, Weijun Fu, Jing Lu, Wanting Qiang, Haiyan He, Jin Liu, Ying Yang, Zhongyuan Feng, Lina Jin, Xiaoqiang Fan, Jia Liu, Qi Zhang, Lianjun Shen, Lihong Weng, Wei Cao
Journal: Blood
Blood (2022) 140 (Supplement 1): 889–890.
https://doi.org/10.1182/blood-2022-162295
Published: 2022
Journal Articles

Plasma Cell-Free DNA Chromosomal Instability As Surrogate Biomarker of Treatment Response and Minimal Residual Diseases for Multiple Myeloma

Juan Du, Jr., MD, Baoan Chen, MDPhD, Wanting Qiang, Yanchun Jia, Jing Lu, MD, Lu Li, Jing Liu, Hua Jiang, MD, Ziliang Qian, Weijun Fu, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29.
https://doi.org/10.1182/blood-2020-138783
Published: 2020
Journal Articles

Clinical Results of a Multicenter Study of the First-in-Human Dual BCMA and CD19 Targeted Novel Platform Fast CAR-T Cell Therapy for Patients with Relapsed/Refractory Multiple Myeloma

Hua Jiang, MD, Baoxia Dong, MD PhD, Li Gao, Li Liu, MD, Jian Ge, Aili He, Juan Du, Jr., MD, Lu Li, Jing Lu, MD, Xiequn Chen, Yi Zhao, Yu Han, Yuezhang Chen, Yuesheng Xu, Hua Zhang, Jiaping He, Huan Shi, Cong Han, Xun Ye, Zhenguang Wang, Jia Liu, Lianjun Shen, MD, Wei Cao, Martina Sersch, MD PhD, Weijun Fu, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-138614
Published: 2020
Journal Articles

Cell-Free DNA Analysis Demonstrates Comprehensive Genomic Profiling and a Facile Method to Sensitively in Multiple Myeloma

Juan Du, MD PhD, Jing Lu, Wanting Qiang, Lu Li, Jin Liu, Hua Jiang, MD, Ziliang Qian, PhD, Baoan Chen, MD PhD, Weijun Fu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5603.
https://doi.org/10.1182/blood-2018-99-116260
Published: 2018
Journal Articles

Ikaros Family Zinc Finger 1 Mutation Is a Poor Prognosis Factor of Adult B Cell Acute Lymphoblastic Leukemia

Shanhao Tang, Hongjie Shen, Xinliang Mao, MD PhD, Haiping Dai, Xiaming Zhu, Shengli Xue, Zixuan Ding, Jing Lu, Depei Wu, MD, XiaoWen Tang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5117.
https://doi.org/10.1182/blood.V130.Suppl_1.5117.5117
Published: 2017
Journal Articles

Prognostic Impact of FLT3-ITD and DNMT3A R882 Double Mutations in Patients with Acute Myeloid Leukemia

Shanhao Tang, Xiaowen Tang, MD, Hongjie Shen, Shengli Xue, Tingjing Wang, Jing Lu, Jia Yin, Depei Wu, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5244.
https://doi.org/10.1182/blood.V128.22.5244.5244
Published: 2016
Journal Articles

BRD4 Degradation By Protacs Represents a More Effective Therapeutic Strategy Than BRD4 Inhibitors in DLBCL

Jing Lu, PhD, Yimin Qian, PhD, Kanak Raina, PhD, Martha Altieri, MS, Hanqing Dong, PhD, Jing Wang, PhD, Xin Chen, PhD, Andrew Crew, PhD, Kevin Coleman, PhD, Craig Crews, PhD, James Winkler, PhD
Journal: Blood
Blood (2015) 126 (23): 2050.
https://doi.org/10.1182/blood.V126.23.2050.2050
Published: 2015
Journal Articles

BRD4 Proteolysis Targeting Chimera (PROTAC) Leads to Sustained Degradation of BRD4 with Broad Activity Against Acute Leukemias and Overcomes Stroma Mediated Resistance By Modulating Surface Expression of CXCR4

Sujan Piya, Teresa McQueen, Duncan Mak, BSc, MPhil, Marina Konopleva, MD PhD, Patrick Zweidler-McKay, MD PhD, Jing Lu, PhD, Yimin Qian, PhD, Michael Andreeff, MD PhD, Gautam Borthakur, MD
Journal: Blood
Blood (2015) 126 (23): 675.
https://doi.org/10.1182/blood.V126.23.675.675
Published: 2015
Journal Articles

Proteolytic Targeting Chimeric Molecules (PROTACs) Specific for Bromodomain-Containing Protein (BRD) 4 Are Active Against Pre-Clinical Models of Multiple Myeloma

Xiaohui Zhang, MD, PhD, Jing Lu, PhD, Yimin Qian, PhD, Robert Z. Orlowski, PhD, MD
Journal: Blood
Blood (2015) 126 (23): 917.
https://doi.org/10.1182/blood.V126.23.917.917
Published: 2015
Journal Articles

Exome Sequencing Identifies Somatic Mutations of DDX3X in Natural Killer/T-Cell Lymphoma

Lu Jiang, PhD, Zhao-Hui Gu, PhD, Zi-Xun Yan, PhD, Xia Zhao, MD, Yin-Yin Xie, PhD, Zi-Guan Zhang, B.S., Chun-Ming Pan, M.S., Yuan Hu, MD, Chang-Ping Cai, MD, Ying Dong, MD, Li Wang, MD, Yang Shen, MD, Guoyu Meng, PhD, Jian-Feng Zhou, MD, PhD, Jian-Da Hu, MD, PhD, Jin-Fen Wang, MD, Lin-Hua Yang, MD, Feng Zhang, MD, Jian-Min Wang, MD, Zhao Wang, MD, Zhi-Gang Peng, MD, Fang-Yuan Chen, MD, Zi-Min Sun, MD, Hao Ding, MD, Jin-Yan Huang, PhD, Yuan-Hua Liu, MD, Jumei Shi, MD, PhD, Jian Hou, MD, Jin-Song Yan, MD, PhD, Jing-Yi Shi, PhD, Lan Xu, PhD, Yang Li, MD, Jing Lu, B.S., Zhong Zheng, MD, Wen Xue, B.S., Wei-Li Zhao, MD, PhD, Zhu Chen, MD, PhD, Sai-Juan Chen, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 1663.
https://doi.org/10.1182/blood.V124.21.1663.1663
Published: 2014
Journal Articles

Genome-Wide Abnormality Patterns of B-Lineage Acute Lymphoblastic Leukemia in Adults in Comparison with Pediatric Cases

Bai-Yan Wang, MD, PhD, Yuan-Fang Liu, MD, PhD, Jing-Yan Tang, MD, Zhao-Hui Gu, PhD, Wei-Na Zhang, MD, Zi-Guan Zhang, B.S., Qiang Wang, MD, Bing Chen, MD, PhD, Sheng-Yue Wang, PhD, Yong-Mei Zhu, M.S., Jun-Min Li, MD, PhD, Jin Wang, Yun Bai, PhD, Gang Lu, M.S., Min-Jun Yang, PhD, Jin-Li Zhang, M.S., Jing-Yi Shi, PhD, Kan-Kan Wang, PhD, Chun-Ming Pan, M.S., Jing Lu, B.S., Lu Jiang, PhD, Yang Li, MD, Chun-Jun Zhao, B.S., Jing Chen, MD, PhD, Long-Jun Gu, MD, Jian-Qing Mi, MD, PhD, Ben-Shang Li, MD, PhD, Zhu Chen, MD, PhD, Sai-Juan Chen, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 3786.
https://doi.org/10.1182/blood.V124.21.3786.3786
Published: 2014
Journal Articles

Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation

Jing Lu, Tatiana Zavorotinskaya, Yumin Dai, Xiao-Hong Niu, Joseph Castillo, Janet Sim, Jianjun Yu, Yingyun Wang, John L. Langowski, Jocelyn Holash, Kevin Shannon, Pablo D. Garcia
Journal: Blood
Blood (2013) 122 (9): 1610–1620.
https://doi.org/10.1182/blood-2013-01-481457
Published: 2013
Includes: Supplemental data
Journal Articles

E3 Ligase c-CBL Mediates Ubiquitination-Proteasomal Degradation of BCR-ABL and Therapeutic Effects against BCR-ABL Leukemia.

Jianhua Mao, PHD, Xiaoyan Sun, PHD, candidate, Qun-Ye Zhang, Qiu-Hua Huang, Ping Liu, Yinyin Xie, Bachelor, Jing Lu, Saijuan Chen, Zhu Chen
Journal: Blood
Blood (2009) 114 (22): 3257.
https://doi.org/10.1182/blood.V114.22.3257.3257
Published: 2009