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Journal Articles

Venetoclax and Decitabine Compared with Standard Intensive Chemotherapy As Induction Therapy in Newly Diagnosed Acute Myeloid Leukemia: Updated Results of a Multicenter, Randomized, Phase 2b Trial

Jing Lu, Shengli Xue, Ying Wang, Xuefeng He, Xiaohui Hu, Miao Miao, Yang Zhang, Zaixiang Tang, Jundan Xie, Xiaofei Yang, Mingzhu Xu, Yaoyao Shen, Feng Du, Qian Vicky Wu, Mengxing Xue, Yun Wang, Ailing Deng, Xueqing Dou, Haiping Dai, Depei Wu, Suning Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 971.
https://doi.org/10.1182/blood-2024-202801
Published: 2024
Journal Articles

Ponatinib 2-Year Efficacy, Safety and Health-Related Quality of Life in Patients with Philadelphia Chromosome-Positive Leukemia: An Open-Label, Multicenter, Phase 2 Clinical Trial in China

Lu Yu, Huifang Wang, Xiaoli Liu, Bingcheng Liu, Xielan Zhao, Qun He, Qingshu Zeng, Zimin Sun, Ting Liu, Huanling Zhu, Zhuogang Liu, Xin Du, Jie Jin, Li Meng, Ming Hou, Suning Chen, Linhua Yang, Mingji Xian, Yoshitaka Kotobuki, Shuang Zhang, Qian Jiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6602.
https://doi.org/10.1182/blood-2024-208258
Published: 2024
Journal Articles

Comprehensive Clinical and Molecular Characterization Reveals Rara As the Most Frequent Torque Teno Mini Virus Insertion Site and Defines a Distinct Ttmv::Rara Driven APL-like Leukemia Subtype

Shu Sun, Yongjing Liu, Qing-Yu Xu, Xiaosu Zhou, Lijun Wen, Li Chen, Jiaqi Chen, Huili Wang, Xue Chen, Jiacheng Lou, Huyong Zheng, Yangyang Xie, Linya Wang, Futian Ma, Lihua Yang, Xianjing Wang, Wen Gao, Yin Wu, Leping Zhang, Shuhong Shen, Suning Chen, Kankan Wang, Hongxing Liu, Jinyan Huang, Hong-Hu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1547.
https://doi.org/10.1182/blood-2024-202323
Published: 2024
Journal Articles

Variables Associated with Outcomes in Patients with Chronic Neutrophilic Leukemia with CSF3R T618I : A Multi-Centre Retrospective Study

Qian Jiang, Na Xu, Xiaoli Liu, Li Meng, Suning Chen, Jianyong Li, Linhua Yang, Chun-Yan Chen, Limei Chen, Jie Sun, Ling Pan, Minghui Duan, Hongmei Jing, Jinhai Ren, Fengru Lin, Xuemei Qin, Junqing Xu, Robert Peter Gale, Mingfeng Zhao, Zhilan Pan, Xianhua Yuan, Lijuan Cui, Zhijian Xiao, Li Weiming
Journal: Blood
Blood (2024) 144 (Supplement 1): 1793.
https://doi.org/10.1182/blood-2024-207591
Published: 2024
Journal Articles

Lisaftoclax (APG-2575), a Novel BCL-2 Inhibitor, in Combination with Azacitidine in Treatment of Patients with Myelodysplastic Syndrome (MDS)

Huafeng Wang, Xudong Wei, Yang Liang, Jianyu Weng, Wenjuan He, Chunkang Chang, Suning Chen, Hongbing Ma, Zi Chen, Lichuang Men, Lihui Liu, Xiaohong Tian, Zhang Zhang, Danhua Cong, Dajun Yang, Yifan Zhai, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3202.
https://doi.org/10.1182/blood-2024-205371
Published: 2024
Journal Articles

Subcutaneous Abatacept for Acute Graft-Versus-Host Disease Prophylaxis after Haploidentical Donor Hematopoietic Cell Transplantation: Efficacy, Safety, and Immunologic Effects

Yuhua Ru, Jinjin Zhu, Huanle Gong, Mimi Xu, Ying Wang, Miao Miao, Suning Chen, Xiang Zhang, Yi Fan, Yang Xu, Jia Chen, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3515.
https://doi.org/10.1182/blood-2024-202490
Published: 2024
Journal Articles

Safety and Efficacy of Tgrx-678, a Potent BCR::ABL1 allosteric Inhibitor, in Patients with Tyrosine Kinase Inhibitor Resistant and/or Intolerant Chronic Myeloid Leukemia: Updated Results of Phase 1 Study Tgrx-678 -1001

Qian Jiang, Li Weiming, Yanli Zhang, Qiang Wang, Suning Chen, Bingcheng Liu, Zhuogang Liu, Jie Jin, Zhenfang Liu, Jianyu Weng, Xin Du, Xielan Zhao, Li Meng, Lie Lin, Wanlin Ye, Shujie Yan, Yihan Wang, Jingrong Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 477.
https://doi.org/10.1182/blood-2024-205300
Published: 2024
Journal Articles

Prospective Study of Avapritinib in Patients with Relapsed/Refractory or MRD-Positive Core-Binding Factor Acute Myeloid Leukemia with KIT Mutations

Xueqing Dou, Suning Chen, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 222.
https://doi.org/10.1182/blood-2024-207264
Published: 2024
Journal Articles

A Phase 2 Study of Olverembatinib for the Treatment of Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement

Suning Chen, Depei Wu, Wenzhi CAI, Xueqing Dou, Zhenfang Liu, Yu Zhu, Ying Wang, Chunmei Yang, Jiong Hu, Miao Miao, Xiuzhi Deng, Chunyan Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 1781.
https://doi.org/10.1182/blood-2024-200003
Published: 2024
Journal Articles

Entirely Venetoclax-Based Nonintensive Treatment Regimen for Newly Diagnosed NPM1-Mutated Acute Myeloid Leukemia in the ELN Favorable-Risk Group

Xueqing Dou, Suning Chen, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6032.
https://doi.org/10.1182/blood-2024-201155
Published: 2024
Journal Articles

Efficacy and Safety of Gilteritinib-Based Therapy Combinated with Allo-HSCT in Relapsed or Refractory Acute Myeloid Leukemia Patients with Positive FLT3-ITD Mutation

Jian Zhang, Yang Xu, Shengli Xue, Miao Miao, Ying Wang, Suning Chen, Depei Wu, Huiying Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6079.
https://doi.org/10.1182/blood-2024-198895
Published: 2024
Journal Articles

Sitagliptin for Prophylaxis of aGVHD in Alternative Donor Transplantations: Updated Results of 2 Years Follow-up of a Superiority, Randomized Controlled Phase III Trial

Man Qiao, Suning Chen, Ying Wang, Shengli Xue, Xiaofei Yang, Depei Wu, Huiying Qiu, Yue Han, Yanming Zhang, Kourong Miao, Jihao Zhou, Xiaojin Wu, Miao Miao, Tao You, Xiao Ma, Haiping Dai
Journal: Blood
Blood (2024) 144 (Supplement 1): 4893.
https://doi.org/10.1182/blood-2024-207338
Published: 2024
Journal Articles

Remarkable Molecular Response in Patients with Polycythemia Vera Treated with Ropeginterferon Alfa-2b

Shanshan Suo, Rongfeng Fu, Albert Qin, Zonghong Shao, Jie Bai, Hu Zhou, Na Xu, Suning Chen, Xuelan Zuo, Xin Du, Minghui Duan, Li Wang, Pei Li, Xuhan Zhang, Sujiang Zhang, Daoxiang WU, Jingjing Zhang, Weihong Shen, Wei Wang, Lei Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4562.
https://doi.org/10.1182/blood-2024-203148
Published: 2024
Journal Articles

Olverembatinib-Based Therapy in Patients with Philadelphia Chromosome-Positive Acute Leukemia: A Multi-Centre Retrospective Study from China

Mei Bao, Jian Huang, Huiying Qiu, Suning Chen, Shengli Xue, Xiaofei Yang, Zhenfang Liu, Chunyan Chen, Linhua Yang, Yanping Ma, Li Meng, Yanli Zhang, Li Weiming, Qin Wen, Guohui Li, Lijie Yang, Yanqiu Han, Xiaodong Wang, Yan Wen, Congmeng Lin, Hai Yi, Xingli Zhao, Yanqing Zhang, Yang Song, Qian Jiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4528.
https://doi.org/10.1182/blood-2024-205232
Published: 2024
Journal Articles

Hypomethylating Agent and Venetoclax in Newly Diagnosed and Relapsed CBFβ::MYH11(+) Acute Myeloid Leukemia

Ziyu Feng, Xiaohui Hu, Weiyang Li, Ting Xu, Yang Xu, Shengli Xue, Huiying Qiu, Xiaowen Tang, Yue Han, Suning Chen, Aining Sun, Depei Wu, Ying Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4287.
https://doi.org/10.1182/blood-2024-198648
Published: 2024
Journal Articles

A First-in-Human Phase 1/2 Study of the Menin-KMT2A(MLL1) Inhibitor BN104 in Adult Patients with Relapsed or Refractory Acute Leukemia

Depei Wu, Ying Wang, Suning Chen, Yuhua Li, Rui Huang, Jinhai Ren, Xiaoling Guo, Yan Li, Mingyuan Sun, Xudong Wei, Ruihua Mi, Xiaoyu Zhu, Anyou Wang, He Huang, Yi Luo, Dengju Li, Jin Yin, Xiaojing Yan, Ran Gao, Fei Li, Yu Wang, Bryan Huang, Ye Hua
Journal: Blood
Blood (2024) 144 (Supplement 1): 2879.
https://doi.org/10.1182/blood-2024-198959
Published: 2024
Journal Articles

Comparing the Efficacy and Safety of VAC (Venetoclax, Azacitidine, Chidamide) and VA Regimens As Induction Therapy for Newly Diagnosed Patients with Immunophenotypically Mature Monocytic AML

Kai-Wen Tan, Shanshan Pei, Miao Wang, Lan Dai, Hao Zhang, Chun-Yan Chen, Zhen-Qi Huang, Hai-Ping Dai, Ying Wang, Miao Miao, Yue Han, Xiaowen Tang, Huiying Qiu, Suning Chen, Aining Sun, Depei Wu, Zheng Li, Sheng-Li Xue
Journal: Blood
Blood (2024) 144 (Supplement 1): 1507.
https://doi.org/10.1182/blood-2024-204762
Published: 2024
Journal Articles

A predictive model for therapy failure in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy

Clinical Trials & Observations
Xiaoshuai Zhang, Bingcheng Liu, Jian Huang, Yanli Zhang, Na Xu, Robert Peter Gale, Weiming Li, Xiaoli Liu, Huanling Zhu, Ling Pan, Yunfan Yang, Hai Lin, Xin Du, Rong Liang, Chunyan Chen, Xiaodong Wang, Guohui Li, Zhuogang Liu, Yanqing Zhang, Zhenfang Liu, Jianda Hu, Chunshui Liu, Fei Li, Wei Yang, Li Meng, Yanqiu Han, Li’e Lin, Zhenyu Zhao, Chuanqing Tu, Caifeng Zheng, Yanliang Bai, Zeping Zhou, Suning Chen, Huiying Qiu, Lijie Yang, Xiuli Sun, Hui Sun, Li Zhou, Zelin Liu, Danyu Wang, Jianxin Guo, Liping Pang, Qingshu Zeng, Xiaohui Suo, Weihua Zhang, Yuanjun Zheng, Xiaojun Huang, Qian Jiang
Journal: Blood
Blood (2024) 144 (18): 1951–1961.
https://doi.org/10.1182/blood.2024024761
Published: 2024
Includes: Supplemental data
Journal Articles

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Xiaosu Zhou, Xue Chen, Jiaqi Chen, Lijun Wen, Zhanglin Zhang, Ya-Zhen Qin, Panxiang Cao, Haizhou Xing, Yingchang Mi, Wei Wang, Guangsen Zhang, Ji Li, Huanling Wu, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Gaowei Fan, Yang Zhao, David Jin, Xian Zhang, Xiujuan Ma, Qisheng Wu, Zhihua Zhang, Linya Wang, Futian Ma, Xia Xiao, Chengye Wu, Kai Sun, Ruijie Tang, Yun Zhang, Sanyun Wu, Ran Gao, Leping Zhang, Huyong Zheng, Yanli Zhao, Hong-Hu Zhu, Daopei Lu, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2024) 144 (14): 1471–1485.
https://doi.org/10.1182/blood.2024023883
Published: 2024
Includes: Supplemental data
Journal Articles

All-Trans-Retinoic Acid Induction Overcomes Immune Evasion through Downregulating Immune Checkpoint Molecules and Inducing a Cytokine Storm Triggered By Overexpression of S100A8/A9 Signaling

Suning Chen, Lijun Wen, Lijuan Gao, Yayun Du, Yi Xu, Qian Wu, Xiaofei Yang, Jinlan Pan, Mingqing Zhu, Dandan Liu, Jiannong Cen, Hongjie Shen, Zhao Zeng, Jingren Zhang, Haohao Lu, Zhibo Zhang, Yusha Guo, Zheng Wang, Tingting Zhang, Xiebing Bao, Qian Wang, Qinrong Wang, Yang Xu, Jianhong Fu, Huiying Qiu, Xiaowen Tang, Yue Han, Miao Miao, Shengli Xue, Ying Wang, Sudan He, Depei Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4335.
https://doi.org/10.1182/blood-2023-184432
Published: 2023