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Journal Articles

Long-term efficacy and safety of ropeginterferon alfa-2b under its hidat regimen for the treatment of polycythemia vera

Free
Shanshan Suo, Rongfeng Fu, Albert Qin, Zonghong Shao, Jie Bai, Hu Zhu, Na Xu, Suning Chen, Xue Lan Zuo, Xin Du, Minghui Duan, Li Wang, Pei Li, Xuhan Zhang, Sujiang Zhang, Daoxiang WU, Jingjing Zhang, Zhijian Xiao, Lei Zhang, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2039.
https://doi.org/10.1182/blood-2025-2039
Published: 2025
Journal Articles

Prognostic factors for newly diagnosed Acute Myeloid Leukemia with FLT3-TKD - a multicenter retrospective study

Free
Jiaying Lian, Yu Zhu, Zhiling Yan, Qingshu Zeng, Xiaosheng Fang, Suning Chen, Junmin Li, Chunyan Ji, Sili Wang, Fengbo Jin, Fengjiang Zhou, Linhui Hu, Taigang Zhu, Renzhi Pei, Dong Chen, Shuangyue Li, Peipei Ye, Junjie Cao, Ying Lu, East China Leukemia Alliance (Ecla)
Journal: Blood
Blood (2025) 146 (Supplement 1): 5182.
https://doi.org/10.1182/blood-2025-5182
Published: 2025
Journal Articles

Results of POLARIS-1, a global Phase 3 study (Part A): Olverembatinib combined with low-intensity chemotherapy in patients with newly diagnosed (ND) Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL)

Free
Suning Chen, Yu WU, Jianyu Weng, Cheng Zhang, Hongsheng Zhou, Vadim Doronin, Mei Hong, Ying Wang, Xudong Wei, Iurii Osipov, Yulia Alexeeva, Zi Chen, Yanyan Wang, Lichuang Men, Hengbang Wang, Lixin Jiang, Dengkun Xiong, Dajun Yang, Weili Zhao, Yifan Zhai
Journal: Blood
Blood (2025) 146 (Supplement 1): 1574.
https://doi.org/10.1182/blood-2025-1574
Published: 2025
Journal Articles

Efficacy and safety profile of inaticabtagene autoleucel in Chinese patients with Philadelphia chromosome-positive b-ALL: Insights from real-world data

Free
Bailin He, JIN WANG, Er-Lie Jiang, Yuhua Li, Suning Chen, Heng Mei, Ying Wang, Jianmin Yang, Jie Jin, Ji Xu, Meng Lv, Jianxiang Wang, Shengli Xue, Aibin Liang, Li Wang, Mingzhi Zhang, Xudong Wei, Zhenyang Gu, Fei Li, Chong Wang, Peng Zhao, Xin Du, Xianmin Song, Yingchang Mi, Hongsheng Zhou
Journal: Blood
Blood (2025) 146 (Supplement 1): 6855.
https://doi.org/10.1182/blood-2025-6855
Published: 2025
Journal Articles

Efficacy of a venetoclax-based, anthracycline-free regimen in newly diagnosed CBFβ::MYH11(+) acute myeloid leukemia

Free
Ziyu Feng, Jia Chen, Haiping Dai, Xiaohui Hu, Yang Xu, Shengli Xue, Huiying Qiu, Xiaowen Tang, Han Yue, Suning Chen, Depei Wu, Ying Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 1674.
https://doi.org/10.1182/blood-2025-1674
Published: 2025
Journal Articles

Clinical features and outcome of Philadelphia chromosome-positive acute lymphoblastic leukemia: A 15-year retrospective study

Free
Yiyan Zhu, Wenzhi CAI, Xueqing Dou, Ying Wang, Xiaofei Yang, Haiping Dai, Depei Wu, Suning Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 5103.
https://doi.org/10.1182/blood-2025-5103
Published: 2025
Journal Articles

Beyond the unknown: Leveraging machine learning to predict adverse outcomes in pregnant women with aplastic anemia from a representative nationwide cohort

Free
Qiuyu Guo, Zhuo-Yu An, Mengtong Zang, Lu-Lu Wang, JUN Peng, Xia Luo, Bin Chen, Peng Wu, Chunlin Wang, Lingling Yan, Yongping Song, Zhongxing Jiang, Chong Wang, Guomei Fu, Xianlan Zhao, Rong Fu, Ting Wang, Junjie Ma, Yujun Dong, Yu Sun, Suning Chen, Bing Han, Liangming Ma, Jing He, Liansheng Zhang, Wen Zhou, Yanqiu Han, Lan Yang, Cui Lijuan, Hui Ma, Jianxia He, Yanling Zhang, Jie Zhao, Jian-Ying Zhou, Xue Xu, Guoli Liu, Xiuli Sun, Xiaohong Zhang, Meiying Liang, Jianliu Wang, Hai-Xia Fu, Xiangyu Zhao, Lanping Xu, Xiaojun Huang, Xiaohui Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 1413.
https://doi.org/10.1182/blood-2025-1413
Published: 2025
Journal Articles

Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions: A multi-center study in China

Free
Ya-nan Ma, Wenzhi CAI, Hongming Zhu, Ying Lu, Xiaofei Yang, Jian-xin Guo, Depei Wu, Suning Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 7347.
https://doi.org/10.1182/blood-2025-7347
Published: 2025
Journal Articles

KIT mutant/core binding factor (CBF)-negative (CBF-Neg) AML might be an underestimated and distinct subgroup with poor prognosis: A single-center retrospective study

Free
Rui Jiang, Zhibo Zhang, Yizi Liu, Wenqiang Qu, Zhao Zeng, Linlin Wang, Qian Wang, Jia Yin, Depei Wu, Suning Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 7003.
https://doi.org/10.1182/blood-2025-7003
Published: 2025
Journal Articles

Preclinical and clinical Study of olverembatinib in patients with myeloid/lymphoid neoplasms with FGFR1 rearrangement

Free
Wenzhi CAI, Yan Xiong, Xueqing Dou, Zhenfang Liu, Yu Zhu, Ying Wang, Chunmei Yang, Jiong Hu, Miao Miao, Lihua Sun, Chen Chunyan, Xiuzhi Deng, Xiaolu Zhu, Xiaosheng Fang, Xiaojing Yan, Guoqiang Lin, Chenglu Yuan, Xingxia Zhang, Depei Wu, Suning Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 1979.
https://doi.org/10.1182/blood-2025-1979
Published: 2025
Journal Articles

Safety, tolerability and efficacy of mesutoclax to treat patients with myeloid malignancies

Free
Qian Jiang, Huafeng Wang, Xingli Zhao, Suning Chen, Shuo Ma, Di Zhu, Weige Wang, Renbin Zhao, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 3417.
https://doi.org/10.1182/blood-2025-3417
Published: 2025
Journal Articles

Adult acute myeloid leukemia with NUP98 rearrangement benefits from targeted therapy and bone marrow transplantation

Free
Hongming Zhu, Yunxiang Zhang, Xia Li, Huafeng Wang, Huarong Zhou, Fengbo Jin, Zhenqi Huang, Yu Zhu, Zheng Ge, Ying Lu, Weimin Chen, Bing Xu, Taigang Zhu, Xiaofei Yang, Shaolei Zang, Chunyan Ji, Qingshu Zeng, Shaoyuan Wang, Suning Chen, Jie Jin, Jiong Hu, Yang Shen, Junmin Li, East China Leukemia Alliance (Ecla)
Journal: Blood
Blood (2025) 146 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2025-3391
Published: 2025
Journal Articles

Characteristics and clinical outcomes of ND-AML patients with bcor/bcorl1 mutations

Free
Shaolei Zang, Chunyan Ji, Xiaosheng Fang, Qingshu Zeng, Suning Chen, Zheng Ge, Zhiling Yan, Junmin Li, Yu Zhu, Shaoyuan Wang, Min Ji, Zhenqi Huang, Xueqing Dou, Hongming Zhu, Bing Xu, Huarong Zhou, Zhiyong Zeng, Hao Chen, Jingtao Wang, Huafeng Wang, Jie Jin, Jingjing Ye, East China Leukemia Alliance China
Journal: Blood
Blood (2025) 146 (Supplement 1): 7005.
https://doi.org/10.1182/blood-2025-7005
Published: 2025
Journal Articles

Olverembatinib (HQP1351) demonstrates efficacy vs. best available therapy (BAT) in patients (pts) with tyrosine kinase inhibitor (TKI)-resistant chronic-Phase chronic myeloid leukemia (CML-CP) in a registrational randomized Phase 2 trial: Up to 4-year follow-up including patients without T315I mutations

Free
Qian Jiang, Zongru Li, Yanli Zhang, Yu Hu, Weiming Li, Yongping Song, Junmin Li, Li Zhou, Bingcheng LIU, Xiaoli Liu, Na Xu, Suning Chen, Zhenfang LIU, Huangling Zhu, Jie Jin, He Huang, Sixuan Qian, Li Meng, Xin Du, Xielan Zhao, Sujun Gao, Yang Liang, Ming Hou, Wei Wang, Zi Chen, Qian Niu, Lichuang Men, Dajun Yang, Yifan Zhai, Xiaojun Huang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3788.
https://doi.org/10.1182/blood-2025-3788
Published: 2025
Journal Articles

Phase 1/2, multi-center, open-label clinical study to evaluate the safety, pharmacokinetics, and efficacy of Zefamenib combined with chemotherapy or targeted Agents in patients with Acute Myeloid Leukemia

Free
Haiping Dai, Depei Wu, Suning Chen, Yu Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 8257.
https://doi.org/10.1182/blood-2025-8257
Published: 2025
Journal Articles

Ivosidenib combined with venetoclax and azacitidine for the treatment of newly diagnosed IDH1-mutant Acute Myeloid Leukemia: A prospective, two cohorts, multicenter study

Free
Haiping Dai, Depei Wu, Suning Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 8249.
https://doi.org/10.1182/blood-2025-8249
Published: 2025
Journal Articles

Efficacy of tgrx-678, a potent BCR::ABL1 allosteric inhibitor, in CML-CP and CML-AP patients harboring T315I mutation: Results from a phase 1 study

Free
Qian Jiang, Weiming Li, Yanli Zhang, Qiang WANG, Suning Chen, Bingcheng LIU, Jie Jin, Zhenfang Liu, Zhuogang Liu, Jianyu Weng, Xin Du, Xielan Zhao, Li Meng, Shujie Yan, xiaomeng Dong, Yihan Wang, Jingrong Cao
Journal: Blood
Blood (2025) 146 (Supplement 1): 902.
https://doi.org/10.1182/blood-2025-902
Published: 2025
Journal Articles

Phase 1/2, multi-center, open-label clinical study to evaluate the safety, pharmacokinetics, and efficacy of zefamenib in patients with relapsed/refractory acute leukemia

Free
Depei Wu, Ying Wang, Suning Chen, Yuhua Li, Rui Huang, Xudong Wei, Ruihua Mi, Mingyuan Sun, Yan Li, He Huang, Yi Luo, Bei Liu, Pengcheng He, Dengju Li, Xiaoyu Zhu, Fei Li, Jinhai Ren, Jian Ge, Zhenfang Liu, Songfu Jiang, Xiaofan Zhu, Wenting Hu, Wei WANG, Yuping Gong, Jiani Yin, Prapti Patel, Xiaojun Xu, Meng Lv, Yu Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 5209.
https://doi.org/10.1182/blood-2025-5209
Published: 2025
Journal Articles

Chemo-free regimen based on venetoclax and azacytidine as induction therapy for adults with newly-diagnosed mixed phenotype acute leukemia

Free
Jia Chen, Ying Zhang, Yi Fan, Mimi Xu, Shengli Xue, Xiaowen Tang, Miao Miao, Huiying Qiu, Suning Chen, Yang Xu, Xiang Zhang, Huanle Gong, Depei Wu
Journal: Blood
Blood (2025) 146 (Supplement 1): 6904.
https://doi.org/10.1182/blood-2025-6904
Published: 2025
Journal Articles

Efficacy and safety profile of inaticabtagene autoleucel in Chinese patients with B-cell acute lymphoblastic leukemia: Insights from real-world data

Free
JIN WANG, Hongsheng Zhou, Er-Lie Jiang, Yuhua Li, Suning Chen, Xin Du, Ji Xu, Jie Jin, Heng Mei, Xianmin Song, Jianmin Yang, Chong Wang, Aibin Liang, Guangxun Gao, Shengli Xue, Qian Jiang, Meng Lv, Xi Zhang, Xiaobing Huang, Baohong Ping, Xudong Wei, Shaowei Qiu, Liye Zhong, Feng Zhu, Hongmei Jing, Li Wang, Lu Wang, Xinsheng Xie, Pengcheng He, Zhenyang Gu, Ruihua Mi, Yang Liang, Yingchang Mi, Yu Jing, Zengjun Li, Fei Li, Mingzhi Zhang, Zhiqiang Sun, Peng Zhao, Jing Huang, Jian Li, Jianxiang Wang, Ying Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 5122.
https://doi.org/10.1182/blood-2025-5122
Published: 2025