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Journal Articles

Azacitidine, Venetoclax Combined with Chidamide (ABC-14 Regimen) As an Induction Therapy for Newly Diagnosed AML: A Real-World Retrospective Analysis By the ABC-14 Collaboration Group

Jianyu Weng, Chengxin Deng, Zhenqian Huang, Yuming Zhang, Wang Ying, Minming Li, Ping Wu, Honghua He, Xu Ye, Yirong Jiang, Min Dong, Zhenfang Liu, Xiaoliang Li, Runhui Zheng, Maoquan Zou, Lie Lin, Ying Zhao, Xiangzhong Zhang, Shuqin Cheng, Ziwen Guo, Xuejie Jiang, Zhilun Li, Jiaqi Tan, Chengwei Luo Luo, Suijing Wu, Peilong Lai, Yangqiu Li, Xin Huang, Xin Du
Journal: Blood
Blood (2024) 144 (Supplement 1): 6014.
https://doi.org/10.1182/blood-2024-210211
Published: 2024
Journal Articles

Ponatinib 2-Year Efficacy, Safety and Health-Related Quality of Life in Patients with Philadelphia Chromosome-Positive Leukemia: An Open-Label, Multicenter, Phase 2 Clinical Trial in China

Lu Yu, Huifang Wang, Xiaoli Liu, Bingcheng Liu, Xielan Zhao, Qun He, Qingshu Zeng, Zimin Sun, Ting Liu, Huanling Zhu, Zhuogang Liu, Xin Du, Jie Jin, Li Meng, Ming Hou, Suning Chen, Linhua Yang, Mingji Xian, Yoshitaka Kotobuki, Shuang Zhang, Qian Jiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6602.
https://doi.org/10.1182/blood-2024-208258
Published: 2024
Journal Articles

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Feng Xue, Mankai Ju, Tienan Zhu, ZePing Zhou, Jing Sun, Linhua Yang, Zhenyu Yan, Hu Zhou, Xin Du, Changcheng Zheng, Xia Wu, Xiao Xiao, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3582.
https://doi.org/10.1182/blood-2024-204715
Published: 2024
Journal Articles

Isatuximab Plus Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Versus Vrd in Chinese Patients with Newly Diagnosed Multiple Myeloma Who Are Ineligible for Transplant: IMROZ Subgroup Analysis

Gang An, Zhuogang Liu, Jie Jin, Zhen Cai, Wei Li, Zhongjun Xia, Xinan Cen, Yu Hu, Jian-Qing Mi, Hongmei Jing, Rong Zhan, Xiaoyan Qu, Xin Du, Dan Gao, Liang Zhao, Lugui Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 7055.
https://doi.org/10.1182/blood-2024-199908
Published: 2024
Journal Articles

Post Hoc Analysis of Phase III Gecacitinib Clinical Trial Outcomes: Enhanced Understanding and Implications

Yi Zhang, Hu Zhou, Shanshan Suo, Junling Zhuang, Linhua Yang, Aili He, Qingchi Liu, Xin Du, Sujun Gao, Yarong Li, Yan Li, Yuqing Chen, Wen Wu, Huanling Zhu, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Hongmei Jing, Jishi Wang, Na Xu, Lingling Yue, Cuiping Zheng, ZePing Zhou, Chenghao Jin, Xin Li, Lin Liu, Yajing Xu, Dengshu Wu, Feng Zhang, Jin Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2024-202790
Published: 2024
Journal Articles

Olverembatinib-Therapy in Patients with Accelerated-Phase Chronic Myeloid Leukaemia: A Multi-Centre Retrospective Study from China

Mengyao Yuan, Li Zhou, Xin Du, Jianyu Weng, Linhua Yang, Yanping Ma, Shasha Zhao, Zhenfang Liu, Qin Wen, Qingxian Bai, Xianqi Feng, Yanqiu Han, Aifang Li, Chunshui Liu, Qing Leng, Li Meng, Baohong Wang, Xuehong Ran, Xiaodong Wang, Haiguo Zhang, Yun Zeng, Yanli Zhang, Qian Jiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1767.
https://doi.org/10.1182/blood-2024-206453
Published: 2024
Journal Articles

Poor Response of Venetoclax/Azacitidine in Monocytic-like Acute Myeloid Leukemia Might be Associated with Genetic Patterns and Could be Improved By Addition of Homoharringtonine

Guopan Yu, Yishan Chen, Zhao Yin, Yu Zhang, Weihua Zhao, Guangyang Weng, Xin Du, Danian Nie, Ziwen Guo, Zhiqiang Sun, Hongyu Zhang, Dongjun Lin, Xinquan Liang, Pengcheng Shi, Xuejie Jiang, Dan Xu, Li Xuan, Baohong Ping, Qifa Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1516.
https://doi.org/10.1182/blood-2024-201974
Published: 2024
Journal Articles

Safety and Efficacy of Tgrx-678, a Potent BCR::ABL1 allosteric Inhibitor, in Patients with Tyrosine Kinase Inhibitor Resistant and/or Intolerant Chronic Myeloid Leukemia: Updated Results of Phase 1 Study Tgrx-678 -1001

Qian Jiang, Li Weiming, Yanli Zhang, Qiang Wang, Suning Chen, Bingcheng Liu, Zhuogang Liu, Jie Jin, Zhenfang Liu, Jianyu Weng, Xin Du, Xielan Zhao, Li Meng, Lie Lin, Wanlin Ye, Shujie Yan, Yihan Wang, Jingrong Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 477.
https://doi.org/10.1182/blood-2024-205300
Published: 2024
Journal Articles

Comparison of Outcomes between Haploidentical and Matched Related Donors for Chronic Myelomonocytic Leukemia: A Multicenter Real-World Study

Yuqian Sun, Lixin Wu, Yicheng Zhang, Ya-Jing Xu, Xiaobing Huang, Baodong Ye, Hailong Yuan, Jianying Zhou, Sujun Gao, Fang Zhou, Yue Liu, Xianmin Song, Yu Cai, Xiaoliang Liu, Yi Luo, Luxin Yang, Jianmin Yang, Libing Wang, Yuhua Li, Rui Huang, Shunqing Wang, Ming Zhou, Yujun Dong, Qian Wang, Yimei Feng, Xin Du, Wei Ling, Han Zhu, Zunmin Zhu, Xiangli Chen, Shiyun Wang, Fankai Meng, Kehong Bi, Ning Huang, Ming Jiang, Ting Niu, Jie Ji, Dingming Wan, Bian Zhilei, Yi Chen, Li Liu, Xueqian Yan, Xi Yang, Hai Yi, Xudong Wei, Xin Li, Qian Cheng, Chenglu Yuan, Wen Wang, Yuhong Zhou, Yu-Hong Chen, Fengrong WANG, YuanYuan Zhang, Zhi-Dong Wang, Xiao-Dong Mo, Wei Han, Jing-Zhi Wang, Yu Wang, Huan Chen, Xiangyu Zhao, Ying-jun Chang, Kaiyan Liu, Jia Feng, LanPing Xu, Hongyu Zhang, Xi Zhang, Xiaojun Huang, Xiaohui Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2187.
https://doi.org/10.1182/blood-2024-206919
Published: 2024
Journal Articles

SRSF2 Mutation Cooperates with ASXL1 Mutation to Promote the Development of Myeloproliferative Variant of Chronic Myelomonocytic Leukemia

Jiaojiao Bai, Chen Qiu, Ming Yao, Chengxin Deng, Minming Li, Suxia Geng, Junfei Huang, Yangpeng Chen, Yuan Zhou, Xin Du
Journal: Blood
Blood (2024) 144 (Supplement 1): 6690.
https://doi.org/10.1182/blood-2024-205576
Published: 2024
Journal Articles

Single-Cell Analysis Reveals Altered Tumor Microenvironments of Relapse/ Refractory and Remission-Associated Acute Myeloid Leukemia Treated By ABC-14 Regimen

Xin Huang, Minming Li, Ping Wu, Chengxin Deng, Zesheng Lu, Yulian Wang, Suxia Geng, Chengwei Luo Luo, Peilong Lai, Xin Du, Jianyu Weng
Journal: Blood
Blood (2024) 144 (Supplement 1): 5802.
https://doi.org/10.1182/blood-2024-204516
Published: 2024
Journal Articles

Subgroup Analyses of Phase 2 Study: Evaluating the Efficacy of Fully Human BCMA-Targeting CAR T Cells (Zevorcabtagene Autoleucel) in Patients with Relapsed/Refractory Multiple Myeloma

Wenming Chen, Chengcheng Fu, Baijun Fang, Aibin Liang, Zhongjun Xia, Yanjuan He, Jin Lu, Hui Liu, Ming Hou, Zhen Cai, Wei Yang, Siguo Hao, Songfu Jiang, Hongmei Jing, Jing Liu, Xin Du, Rong Fu, Heng Mei, Zunmin Zhu, Yanli Yang, Hong Liu, Xingxing Meng, Nishanthan Rajakumaraswamy, Wei Zheng, Huamao Wang, Zonghai Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 4762.
https://doi.org/10.1182/blood-2024-204620
Published: 2024
Journal Articles

Multi-Omics Profiling Reveals Tumor Cellular Landscape and Metabolism Remodeling during Extranodal Natural Killer/T-Cell Lymphoma (ENKTL) Metastasis and Progression

Jinhua Liang, Kai-Xin Du, Yue Li, Tong-Yao Xing, Hao-Rui Shen, Jiazhu Wu, Hua Yin, Li Wang, Jianyong Li, Xu Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 2961.
https://doi.org/10.1182/blood-2024-201455
Published: 2024
Journal Articles

Weekly Selinexor, Bortizomib and Dexamethasone (SVd) Versus Twice Weekly Bortizomib and Dexamethasone (Vd) in Chinese Patients with Relapsed and Refractory Multiple Myeloma (RRMM): Primary Analysis of Phase 3 Bench Study

Jin Lu, Liangquan Geng, Lijuan Chen, Peng Liu, Yuping Zhong, Zhuogang Liu, Zhongjun Xia, Jianqing Mi, Chunrui Li, Xi Zhang, Yanjuan He, Yongqiang Wei, Baijun Fang, Fei Li, Zhen Cai, Yafei Wang, Dongping Huang, Hong Liu, Ming Hou, Rong Fu, Xin Du, Xiaosheng Fang, Qingshu Zeng, Wen Gao, Wei Wang, Chunkang Chang, Guifang Ouyang, Jing Liu, Jianyu Weng, Xiaobing Huang, Yang Yu, Zhi Guo, Jun Zhao, Jian Hou
Journal: Blood
Blood (2024) 144 (Supplement 1): 4748.
https://doi.org/10.1182/blood-2024-202893
Published: 2024
Journal Articles

SG301, a Novel Anti-CD38 Monoclonal Antibody, in Patients with Relapsed/Refractory Multiple Myeloma: A First-in-Human, Multicentre, Phase 1 Trial

Ying Tian, Keshu Zhou, Quande Lin, Wenbin Qian, Wei Yang, Li Bao, Guolin Yuan, Xiaojing Yan, Liangming Ma, Xin Zhou, Lihong Liu, Fangbing Zhu, Xuelan Zuo, Xin Du, Xu Ji, Xuzhao Zhang, Jing Shen, Hai Zhou, Na Li, Wenming Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 4746.
https://doi.org/10.1182/blood-2024-199381
Published: 2024
Journal Articles

Preliminary Efficacy and Safety Results of TQB3473, a Novel Syk Inhibitor, in Adult Patients with Immune Thrombocytopenia (ITP)

Hu Zhou, Bingjie Ding, Tiejun Gong, Xiangzhou Du, Xiaoming Li, Yinghui Lai, Zhenyu Yan, Rong Fu, Xin Du, Qian Zhao
Journal: Blood
Blood (2024) 144 (Supplement 1): 711.
https://doi.org/10.1182/blood-2024-198573
Published: 2024
Journal Articles

MRD-Driven Prophylactic or Pre-Emptive Intervention with Chidamide-Based Treatment for High-Risk AML Relapse Post-Transplantation: A Real-World Experience from a Chinese Single Center

Ping Wu, Wei Ling, Chengwei Luo Luo, Lisi Huang, Ruohao Xu, Xiaoling Liang, Jiaqi Tan, Jinghua Wang, Peilong Lai, Suijing Wu, Birong Li, Haijie Huang, Suxia Geng, Xin Du, Jianyu Weng
Journal: Blood
Blood (2024) 144 (Supplement 1): 1575.
https://doi.org/10.1182/blood-2024-210697
Published: 2024
Journal Articles

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Wei Liu, Hu Zhou, Ruibin Huang, Xin Du, ZePing Zhou, Changcheng Zheng, Shifeng Lou, Xinyue Dai, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1213.
https://doi.org/10.1182/blood-2024-199149
Published: 2024
Journal Articles

Long-Term Sovleplenib Treatment of Adults with Primary Immune Thrombocytopenia in China

Yu Hu, Renchi Yang, Xiaofan Liu, Heng Mei, Hu Zhou, Shujie Wang, Ruibin Huang, Yi Wang, Xin Du, Jing Sun, Zeping Zhou, Zhenyu Yan, Wenming Chen, Wei Wang, Qingchi Liu, Qingshu Zeng, Yuping Gong, Jie Yin, Xuliang Shen, Baodong Ye, Yun Chen, Yajing Xu, Huiping Sun, Yunfeng Cheng, Zhuogang Liu, Chunling Wang, Guolin Yuan, Xiaohui Zhang, Xin Li, Peng Cheng, Xinhong Guo, Zhongxing Jiang, Feng'e Yang, Linhua Yang, Chengwei Luo Luo, Taiwu Xiao, Hongyan Yin, Xiaojun Guo, Xian Luo, Songhua Fan, Michael M. Shi, Weiguo Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 2558.
https://doi.org/10.1182/blood-2024-204447
Published: 2024
Journal Articles

An Uniquely Designed Asymmetric Bispecific Antibody Against GPRC5D and CD3 (LBL-034) in Patients with Relapsed/Refractory Multiple Myeloma: A Phase I/II, First in Human, Open-Label, Multicenter, Dose Escalation/Expansion Study

Ling Qin, Yuping Zhong, Dongping Huang, Haitang Xie, Xin Du, Aijun Liao, Hongli Zhang, Shengli (Charles) Cai, Jin Lu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4736.
https://doi.org/10.1182/blood-2024-202871
Published: 2024