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Efficacy, Safety, and Survival Findings after Long-Term Follow-up from ZGJAK002, a Phase 2 Study Comparing Jaktinib 100 Mg Twice Daily with 200 Mg Once Daily for Myelofibrosis (MF)

Yi Zhang, Hu Zhou, Zhongxing Jiang, Dengshu Wu, Junling Zhuang, Wei Li, Qian Jiang, Xiuli Wang, Jinwen Huang, Huanling Zhu, Linhua Yang, Xin Du, Fei Li, Ruixiang Xia, Feng Zhang, Jianda Hu, Yan Li, Yu Hu, Jing Liu, Chenghao Jin, Kai Sun, Zeping Zhou, Shanshan Suo, Wenjuan Yu, Jie Jin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1814.
https://doi.org/10.1182/blood-2023-179043
Published: 2023
Journal Articles

Rational Engineering of Minimally Immunogenic Nucleases for Gene Therapy

Rumya Raghavan, Mirco Friedrich, Indigo King, Michael Killian, Michael Platten, Rhiannon Macrae, Yifan Song, Lucas Nivon, Feng Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 7126.
https://doi.org/10.1182/blood-2023-180987
Published: 2023
Journal Articles

Results from a Phase 2 Study of a Novel Janus Kinase Inhibitor in Treatment of Patients with Myelofibrosis

Yi Zhang, Hu Zhou, Zhongxing Jiang, DengShu Wu, Junling Zhuang, Wei Li, Qian Jiang, XiuLi Wang, Jinwen Huang, Huan-Ling Zhu, RuiJuan Zhang, Xin Du, Li Fei, Ruixiang Xiang, Feng Zhang, Jianda Hu, Yan Li, Yu Hu, Jing Liu, ChengHao Jin, Kai Sun, Ze-Ping Zhou, Jie Jin
Journal: Blood
Blood (2021) 138 (Supplement 1): 387.
https://doi.org/10.1182/blood-2021-145664
Published: 2021
Journal Articles

IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis

Yu Gu, Risheng Yang, Ying Yang, Yuanlin Zhao, Andrew Wakeham, Wanda Y. Li, Alan Tseng, Julie Leca, Thorsten Berger, Mary Saunders, Jerome Fortin, Xing Gao, Yuan Yuan, Liming Xiao, Feng Zhang, Lijun Zhang, Guangxun Gao, Wenjing Zhou, Zhe Wang, Tak W. Mak, Jing Ye
Journal: Blood
Blood (2021) 137 (7): 945–958.
https://doi.org/10.1182/blood.2020007075
Published: 2021
Includes: Supplemental data
Journal Articles

Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ

Lei Zhang, Jing Li, Hui Xu, Xianyu Shao, Li Fu, Ye Hou, Caiqing Hao, Wenyan Li, Kanak Joshi, Wei Wei, Yan Xu, Feng Zhang, Shaojun Dai, Peter Breslin, Jiwang Zhang, Jun Zhang
Journal: Blood
Blood (2020) 135 (14): 1133–1145.
https://doi.org/10.1182/blood.2019001863
Published: 2020
Includes: Supplemental data
Journal Articles

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

Lei Zhang, PhD, Huacheng Luo, PhD, Jing Li, Hong-Min Ni, Mark Sellin, Feng Zhang, Jun Zhang, Peter Breslin, PhD, Wei Wei, William Small, Jr., Wen-Xin Ding, Suming Huang, PhD, Jiwang Zhang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3714.
https://doi.org/10.1182/blood-2019-131332
Published: 2019
Journal Articles

Biology and Application of Genome Editing

Feng Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-22.
https://doi.org/10.1182/blood-2019-121282
Published: 2019
Journal Articles

Precision Assessment of on- and Off-Target Effects of mTOR Kinase Inhibitors in a Mouse Model

Cuiqing Fan, PhD, Xiongwei Cai, PhD, Feng Zhang, PhDcandidate, Cindy Hochstetler, PhDcandidate, Xiaoyi Chen, PhD, Fukun Guo, PhD, Weidong Tian, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2018-99-115225
Published: 2018
Journal Articles

mTOR Restricts Chromatin Access and Genomic Activity to Maintain Hematopoietic Stem Cell Quiescence and Engraftment

Cuiqing Fan, PhD, Chuntao Zhao, PhD, Feng Zhang, Xiongwei Cai, PhD, Lingli Xu, Shan Lin, PhD, Xiaoyi Chen, PhD, Fukun Guo, PhD, Richard Q Lu, PhD, Weidong Tian, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2416.
https://doi.org/10.1182/blood.V130.Suppl_1.2416.2416
Published: 2017
Journal Articles

Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing)

Daniel E. Bauer, MD, PhD, Matthew C. Canver, B.S., Elenoe C. Smith, PhD, Falak Sher, PhD, Luca Pinello, PhD, Neville E. Sanjana, PhD, Ophir Shalem, PhD, Diane D. Chen, B.S., Patrick G. Schupp, B.S., Divya S. Vinjamur, PhD, Sara P. Garcia, PhD, Sidinh Luc, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD, PhD, Yuko Fujiwara, PhD, Takahiro Maeda, MD, PhD, Guo-Cheng Yuan, PhD, Guillaume Lettre, PhD, Feng Zhang, PhD, Stuart H. Orkin, MD
Journal: Blood
Blood (2015) 126 (23): 638.
https://doi.org/10.1182/blood.V126.23.638.638
Published: 2015
Journal Articles

Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition

Michal Sheffer, PhD, Yiguo Hu, PhD, Ophir Shalem, PhD, Neville Sanjana, PhD, Eugen Dhimolea, PhD, Subhashis Sarkar, PhD, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Richard W.J. Groen, PhD, Feng Zhang, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 273.
https://doi.org/10.1182/blood.V124.21.273.273
Published: 2014
Journal Articles

Exome Sequencing Identifies Somatic Mutations of DDX3X in Natural Killer/T-Cell Lymphoma

Lu Jiang, PhD, Zhao-Hui Gu, PhD, Zi-Xun Yan, PhD, Xia Zhao, MD, Yin-Yin Xie, PhD, Zi-Guan Zhang, B.S., Chun-Ming Pan, M.S., Yuan Hu, MD, Chang-Ping Cai, MD, Ying Dong, MD, Li Wang, MD, Yang Shen, MD, Guoyu Meng, PhD, Jian-Feng Zhou, MD, PhD, Jian-Da Hu, MD, PhD, Jin-Fen Wang, MD, Lin-Hua Yang, MD, Feng Zhang, MD, Jian-Min Wang, MD, Zhao Wang, MD, Zhi-Gang Peng, MD, Fang-Yuan Chen, MD, Zi-Min Sun, MD, Hao Ding, MD, Jin-Yan Huang, PhD, Yuan-Hua Liu, MD, Jumei Shi, MD, PhD, Jian Hou, MD, Jin-Song Yan, MD, PhD, Jing-Yi Shi, PhD, Lan Xu, PhD, Yang Li, MD, Jing Lu, B.S., Zhong Zheng, MD, Wen Xue, B.S., Wei-Li Zhao, MD, PhD, Zhu Chen, MD, PhD, Sai-Juan Chen, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 1663.
https://doi.org/10.1182/blood.V124.21.1663.1663
Published: 2014
Journal Articles

The Role Of Intraplatelet Reactive Oxygen Species In The Regulation Of Platelet Glycoprotein Ibα Ectodomain Shedding

Pingping Zhang, Juan Du, Lili Zhao, Xiujuan Wang, Yiwen Zhang, PhD, Rong Yan, PhD, Jin Dai, Guanglei Liu, Feng Zhang, Kesheng Dai, PhD
Journal: Blood
Blood (2013) 122 (21): 1061.
https://doi.org/10.1182/blood.V122.21.1061.1061
Published: 2013
Journal Articles

Tetraspanin CD151 maintains vascular stability by balancing the forces of cell adhesion and cytoskeletal tension

Feng Zhang, Jarett E. Michaelson, Simon Moshiach, Norman Sachs, Wenyuan Zhao, Yao Sun, Arnoud Sonnenberg, Jill M. Lahti, Hayden Huang, Xin A. Zhang
Journal: Blood
Blood (2011) 118 (15): 4274–4284.
https://doi.org/10.1182/blood-2011-03-339531
Published: 2011
Includes: Multimedia, Supplemental data
Journal Articles

The Cyclin Interactor p26 INCA1 Regulates the Hematopoietic Stem Cell Pool Via CDK Inhibition.

Nicole Baeumer, PhD, Sven Diederichs, PhD, Steffen Koschmieder, MD, Boris V. Skryabin, MD, PhD, Feng Zhang, PhD, Martin Stehling, PhD, Gabriele Koehler, MD, Wolfgang E. Berdel, MD, Hubert Serve, MD, Carsten Mueller-Tidow, MD
Journal: Blood
Blood (2007) 110 (11): 637.
https://doi.org/10.1182/blood.V110.11.637.637
Published: 2007
Journal Articles

Janus kinase 2 is involved in stromal cell–derived factor-1α–induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells

Xue-Feng Zhang, Jian-Feng Wang, Ewa Matczak, JoAnn Proper, Jerome E. Groopman
Journal: Blood
Blood (2001) 97 (11): 3342–3348.
https://doi.org/10.1182/blood.V97.11.3342
Published: 2001
Journal Articles

Absence of Immunogenicity of Diaspirin Cross-Linked Hemoglobin in Humans

Mehul J. Patel, Edwin J. Webb, Tina E. Shelbourn, Cynthia Mattia-Goldberg, Andrew J.T. George, Feng Zhang, Edwin G. Moore, Deanna J. Nelson
Journal: Blood
Blood (1998) 91 (2): 710–716.
https://doi.org/10.1182/blood.V91.2.710
Published: 1998