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Journal Articles

Preliminary Efficacy and Safety Results of TQB3473, a Novel Syk Inhibitor, in Adult Patients with Immune Thrombocytopenia (ITP)

Hu Zhou, Bingjie Ding, Tiejun Gong, Xiangzhou Du, Xiaoming Li, Yinghui Lai, Zhenyu Yan, Rong Fu, Xin Du, Qian Zhao
Journal: Blood
Blood (2024) 144 (Supplement 1): 711.
https://doi.org/10.1182/blood-2024-198573
Published: 2024
Journal Articles

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Feng Xue, Mankai Ju, Tienan Zhu, ZePing Zhou, Jing Sun, Linhua Yang, Zhenyu Yan, Hu Zhou, Xin Du, Changcheng Zheng, Xia Wu, Xiao Xiao, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3582.
https://doi.org/10.1182/blood-2024-204715
Published: 2024
Journal Articles

A Novel JAK2 Inhibitor OB756 in Treatment of Janus Kinase Inhibitor-Naive Patients with Myelofibrosis: A Phase 1/2, Open-Label, Multicenter Study

Yile Zhou, Jian Huang, Bingbing Wen, Hu Zhou, Wei Yang, Lianlian Fan, Tiejun Gong, Sujun Gao, Zongjiu Jiao, Qingchi Liu, Lidong Zhao, Guocai Wu, Cuicui Wu, Jun Wang, Jin Zhang, Jiaping Fu, Zengmei Sheng, Zunmin Zhu, Jian Lu, Yi Zhang, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1808.
https://doi.org/10.1182/blood-2024-212216
Published: 2024
Journal Articles

First in-Class JAK2 Inhibitor OB756 Therapy for Patients with Polycythemia Vera : A Phase 2, Open-Label, Multicenter Study

Jian Huang, Bingbing Wen, Tiejun Gong, Hu Zhou, Lihong Shou, Qingchi Liu, Feng Zhang, Cuicui WU, Wei Yang, Lidong Zhao, Lili Chen, Jian Lu, Yile Zhou, Yi Zhang, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3180.
https://doi.org/10.1182/blood-2024-210330
Published: 2024
Journal Articles

Post Hoc Analysis of Phase III Gecacitinib Clinical Trial Outcomes: Enhanced Understanding and Implications

Yi Zhang, Hu Zhou, Shanshan Suo, Junling Zhuang, Linhua Yang, Aili He, Qingchi Liu, Xin Du, Sujun Gao, Yarong Li, Yan Li, Yuqing Chen, Wen Wu, Huanling Zhu, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Hongmei Jing, Jishi Wang, Na Xu, Lingling Yue, Cuiping Zheng, ZePing Zhou, Chenghao Jin, Xin Li, Lin Liu, Yajing Xu, Dengshu Wu, Feng Zhang, Jin Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2024-202790
Published: 2024
Journal Articles

Optimized Recombinant Human Thrombopoietin(rhTPO) Regimen Versus Eltrombopag for Pre-Treated Patients with Primary Immune Thrombocytopenia: Interim Results from a Prospective, Multicenter, Randomized Trial (TE-ITP study)

Yunfei Chen, Ting Sun, Da Gao, Wei Wang, ZePing Zhou, Guangxun Gao, Yi Wang, Hu Zhou, Yanping Song, Yinghui Lai, Zhenyu Yan, Jinsong Yan, Jie Bai, Lei Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3937.
https://doi.org/10.1182/blood-2024-202716
Published: 2024
Journal Articles

Efficacy and Safety of Beceltinib Capsules in the Treatment of Persistent or Chronic Primary Immune Thrombocytopenia: A Multicenter, Randomized, Open-Label, Phase 1/2 Study

Hu Zhou, Xuewen Song, Zengmei Sheng, Feng Zhang, Guocai Wu, Lidong Zhao, ZePing Zhou, Lihong Shou, Lili Chen, Xiaotao Wang, Jian Huang, Rong Fu, Dan Chen, Ruibin Huang, Zongjiu Jiao, Jian Lu, Yajun Ruan, Yu Jiao
Journal: Blood
Blood (2024) 144 (Supplement 1): 5406.
https://doi.org/10.1182/blood-2024-200074
Published: 2024
Journal Articles

Remarkable Molecular Response in Patients with Polycythemia Vera Treated with Ropeginterferon Alfa-2b

Shanshan Suo, Rongfeng Fu, Albert Qin, Zonghong Shao, Jie Bai, Hu Zhou, Na Xu, Suning Chen, Xuelan Zuo, Xin Du, Minghui Duan, Li Wang, Pei Li, Xuhan Zhang, Sujiang Zhang, Daoxiang WU, Jingjing Zhang, Weihong Shen, Wei Wang, Lei Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4562.
https://doi.org/10.1182/blood-2024-203148
Published: 2024
Journal Articles

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Wei Liu, Hu Zhou, Ruibin Huang, Xin Du, ZePing Zhou, Changcheng Zheng, Shifeng Lou, Xinyue Dai, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1213.
https://doi.org/10.1182/blood-2024-199149
Published: 2024
Journal Articles

Long-Term Sovleplenib Treatment of Adults with Primary Immune Thrombocytopenia in China

Yu Hu, Renchi Yang, Xiaofan Liu, Heng Mei, Hu Zhou, Shujie Wang, Ruibin Huang, Yi Wang, Xin Du, Jing Sun, Zeping Zhou, Zhenyu Yan, Wenming Chen, Wei Wang, Qingchi Liu, Qingshu Zeng, Yuping Gong, Jie Yin, Xuliang Shen, Baodong Ye, Yun Chen, Yajing Xu, Huiping Sun, Yunfeng Cheng, Zhuogang Liu, Chunling Wang, Guolin Yuan, Xiaohui Zhang, Xin Li, Peng Cheng, Xinhong Guo, Zhongxing Jiang, Feng'e Yang, Linhua Yang, Chengwei Luo Luo, Taiwu Xiao, Hongyan Yin, Xiaojun Guo, Xian Luo, Songhua Fan, Michael M. Shi, Weiguo Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 2558.
https://doi.org/10.1182/blood-2024-204447
Published: 2024
Journal Articles

Heritable SETBP1 Mutations Associated with Myelodysplastic Syndrome and Acute Myeloid Leukemia

Jingyi Yang, Shanlan Mo, Xudong Wei, Xiaodong Lv, Ya Zhang, Yuewen Fu, Baijun Fang, Yanli Zhang, Jian Zhou, Hu Zhou, Quande Lin, Delong Liu, Yongping Song, Qianfei Wang, Keshu Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 5684.
https://doi.org/10.1182/blood-2023-182788
Published: 2023
Journal Articles

Single-Dose Rituximab Plus Glucocorticoid Versus Cyclophosphamide Plus Glucocorticoid in Patients with Newly Diagnosed Acquired Hemophilia a: A Multicenter, Open-Label, Randomized Clinical Trial

Wei Liu, Rongfu Zhou, Panjing Wang, Hu Zhou, Jie Bai, Xianghua Wang, Yueshen Ma, Zhen Song, Yunfei Chen, Xiaofan Liu, Rongfeng Fu, Ting Sun, Mankai Ju, Xinyue Dai, Huan Dong, Feng Xue, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2628.
https://doi.org/10.1182/blood-2023-174587
Published: 2023
Journal Articles

Emicizumab Prophylaxis for the Treatment of Chinese Hemophilia A Patients in the Real World: A Multi-Center Retrospective Analysis

Yuan Xu, Ying Wang, Runhui Wu, Changcheng Zheng, Jianwen Xiao, Weiqun Xu, Xiaoqin Feng, Hua Wang, Xiangshan Cao, Liya He, Tianyang Xue, Mingwei Jin, Bingshou Xie, Jing Ling, Lirong Sun, Rui Su, Hongbo Cheng, Yongjun Fang, Bai Li, Ziqiang Yu, Ailing Xue, Mei Sun, Li Yang, Zeping Zhou, Hu Zhou, Jiao Jin, Min Zhou, Rong Chen, Wei Liu, Lei Zhang, Feng Xue, Renchi Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2624.
https://doi.org/10.1182/blood-2023-174698
Published: 2023
Journal Articles

Anti-GPIb/IX Autoantibodies Are Associated with Poor Response to Dexamethasone Combined with Rituximab Therapy in Primary Immune Thrombocytopenia Patients

Bingjie Ding, Hu Zhou, Mengjuan Li, Xuewen Song, Yuanyuan Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3942.
https://doi.org/10.1182/blood-2023-173231
Published: 2023
Journal Articles

The Diversity of FLT3-ITD and the Prognostic Impact in Adult Acute Myeloid Leukemia

Jingyi Yang, Shanlan Mo, Xudong Wei, Xiaodong Lv, Baijun Fang, Yanli Zhang, Jian Zhou, Hu Zhou, Yuewen Fu, Quande Lin, Delong Liu, Yongping Song, Qianfei Wang, Keshu Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 5756.
https://doi.org/10.1182/blood-2023-178989
Published: 2023
Journal Articles

Analysis of Perioperative Factor Replacement Therapy for Hemophilia

Hu Zhou, Bingjie Ding, Peng Zhang, Mengjuan Li, Xuewen Song
Journal: Blood
Blood (2023) 142 (Supplement 1): 5472.
https://doi.org/10.1182/blood-2023-173816
Published: 2023
Journal Articles

Efficacy, Safety, and Survival Findings after Long-Term Follow-up from ZGJAK002, a Phase 2 Study Comparing Jaktinib 100 Mg Twice Daily with 200 Mg Once Daily for Myelofibrosis (MF)

Yi Zhang, Hu Zhou, Zhongxing Jiang, Dengshu Wu, Junling Zhuang, Wei Li, Qian Jiang, Xiuli Wang, Jinwen Huang, Huanling Zhu, Linhua Yang, Xin Du, Fei Li, Ruixiang Xia, Feng Zhang, Jianda Hu, Yan Li, Yu Hu, Jing Liu, Chenghao Jin, Kai Sun, Zeping Zhou, Shanshan Suo, Wenjuan Yu, Jie Jin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1814.
https://doi.org/10.1182/blood-2023-179043
Published: 2023
Journal Articles

Pharmacokinetics, Efficacy and Safety Evaluation of FRSW107 in Previously Treated Hemophilia a Patients: A Multicentre, Open-Label, Non-Randomized Phase III Study

Feng Xue, Hu Zhou, Yun Chen, Jing Sun, Xiaojing Zeng, Chenghao Jin, Pingchong Lei, Zhenyu Li, Yaming Xi, Lirong Sun, Zhongguang Cui, Xielan Zhao, Linhua Yang, Bangshuo Zhang, Aizong Shen, Runhui Wu, Xiaolin Wang, Ling Liu, Yuhua Wang, Lizhi Sun, Yan Xia, Weichuan Mo, Dong Yuan, Jiwei Lou, Taiping Gan, Chengli Hu, Chen Ling, Hongsheng Su, Yali Wang, Baolin Tang, Renchi Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8468–8469.
https://doi.org/10.1182/blood-2022-158760
Published: 2022
Journal Articles

Trial in Progress: An Open-Label, Phase 2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of KP104 in Complement Inhibitor-Naïve Subjects with Paroxysmal Nocturnal Hemoglobinuria

Fengkui Zhang, Bing Han, Guangsheng He, Hu Zhou, Chunrong Wang, Changhe Yue, Jay Ma, Martin Rabe, Helen Fu, Chaomei He, Ping Tsui, Jingtao Wu, Frederick Beddingfield, Wenru Song, Richard Lee
Journal: Blood
Blood (2022) 140 (Supplement 1): 11459–11460.
https://doi.org/10.1182/blood-2022-159172
Published: 2022
Journal Articles

Factor X Activator for Hemophilia Patients with Inhibitors: A Phase 1, First-in-Human, Multi-Center, and Open-Label Trial

Wei Liu, Feng Xue, Rongfeng Fu, Bingjie Ding, Mengjuan Li, Ting Sun, Yunfei Chen, Liu Xiaofan, Mankai Ju, Xinyue Dai, Quanrui Wu, Zan Zhou, Xiaomin Wang, Jiaojiao Yu, Hu Zhou, Renchi Yang, Lei Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8474–8475.
https://doi.org/10.1182/blood-2022-159948
Published: 2022