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Journal Articles

Phase 1/2 studies of DZD8586 in CLL/SLL patients after COVALENT and non-COVALENT BTK inhibitors and BTK degraders – extended follow-up report

Free
Keshu Zhou, Tingyu Wang, Wei Yang, Jian-Qing Mi, Sujun Gao, Huayuan Zhu, Xutao Guo, Kaiyang Ding, Ying Xiang, Huili Cai, Guohui Cui, Yun Zhuang, Hongmei Jing, Liping Su, Rui Huang, Lihua Qiu, Mark Geyer, Wuhan Hui, Geoffrey Chong, Meifang Zheng, Yi Wang, Ying Li, Ke Fang, Chan Cheah, Jianyong Li
Journal: Blood
Blood (2025) 146 (Supplement 1): 3889.
https://doi.org/10.1182/blood-2025-3889
Published: 2025
Journal Articles

Ferritin change and predictors of anemia response in ruxolitinib-intolerant myelofibrosis patients treated with gecacitinib

Free
Yi Zhang, Hu Zhou, Zhijian Xiao, Minghui Duan, Sujun Gao, Guangsheng He, Hongmei Jing, Junmin Li, Liangming Ma, Huanling Zhu, Chunkang Chang, Xin Du, Mei Hong, Xin Li, Qingchi Liu, Wei WANG, Na Xu, Haiping Yang, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2029.
https://doi.org/10.1182/blood-2025-2029
Published: 2025
Journal Articles

Efficacy and safety of gecacitinib in thrombocytopenic myelofibrosis patients

Free
Yi Zhang, Hu Zhou, Junling Zhuang, Zhongxing Jiang, Dengshu Wu, Qingchi Liu, Huanling Zhu, Qike Zhang, Xin Du, Sujun Gao, Qian Jiang, Wei Li, Linhua Yang, Yuqing Chen, Aili He, Jinwen Huang, Yan Li, Xiuli Wang, Guangsheng He, Hongmei Jing, Zhijian Xiao, Minghui Duan, Mei Hong, Fei Li, Yarong Li, Liangming Ma, Jishi Wang, Wei WANG, Wen Wu, Na Xu, Feng Zhang, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2028.
https://doi.org/10.1182/blood-2025-2028
Published: 2025
Journal Articles

Safety and efficacy of the JAK/rock inhibitor rovadicitinib in combination with the bromodomain and extra-terminal inhibitor TQB3617 in patients with myelofibrosis: A phase ib/II study

Free
Chunkang Chang, Xuliang Shen, Hu Zhou, Min Zhang, Zongjiu Jiao, Sujun Gao, Zhenya Hong, Zhihua Zhang, Jianping Hao, Tiejun Gong, Hongmei Ma, Xue Lan Zuo, Guohua Yang, Junying Wu, Luxi Song, Duoer Wu, Dawei Ding, Shanli Lao, Ding Yu
Journal: Blood
Blood (2025) 146 (Supplement 1): 481.
https://doi.org/10.1182/blood-2025-481
Published: 2025
Journal Articles

Results of a registrational Phase 2 study of lisaftoclax monotherapy for treatment of patients (pts) with Relapsed/Refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) who had failed Bruton's tyrosine kinase inhibitors (BTKis)

Free
Keshu Zhou, Tingyu Wang, Ting Niu, Meifang Zheng, Jie Jin, Yang Liang, Rui Huang, Shuangnian Xu, Jianhua Qu, Guohui Cui, Fei Li, Yiming Luo, Ru Feng, Wenzheng Yu, Caixia Li, Zhiling Yan, Xin Zhou, Suijing Wu, Lihong Liu, Yinghua Geng, Jishi Wang, Sujun Gao, Jianfei Fu, Xiaoping Zhang, Chunyan Ji, Qianqian Xiang, Xiongpeng Zhu, Yajing Xu, Li'e Lin, Xiaoyu Zhu, Yuping Zhong, Hongling Peng, Ying Zhao, Hui Zeng, Zhao Wang, Rong Fu, Wenbin Qian, Yingmin Liang, Xiaobing Huang, Yajun Li, Min Yu, Zi Chen, Lei Wang, Lichuang Men, Zhiyan Liang, Shan Zeng, Baoer Lu, Yifan Zhai, Jianyong Li
Journal: Blood
Blood (2025) 146 (Supplement 1): 88.
https://doi.org/10.1182/blood-2025-88
Published: 2025
Journal Articles

Comparison of different dose of anti-T lymphocyte globulin (ATLG) in haploidentical HSCT for gvhd prophylaxis

Free
Yigeng Cao, Rongli Zhang, Jialin Wei, Xiaoliang Liu, GuangCui He, Li Huang, Jianmin Zhang, Qiaoling Ma, Weihua Zhai, Wenbin Cao, Xin Chen, Chen Liang, Donglin Yang, Aiming Pang, Shuangnian Xu, Yi He, Xiangjun Fu, Hai Yi, Yehui Tan, Sujun Gao, Erlie Jiang
Journal: Blood
Blood (2025) 146 (Supplement 1): 2468.
https://doi.org/10.1182/blood-2025-2468
Published: 2025
Journal Articles

Olverembatinib (HQP1351) demonstrates efficacy vs. best available therapy (BAT) in patients (pts) with tyrosine kinase inhibitor (TKI)-resistant chronic-Phase chronic myeloid leukemia (CML-CP) in a registrational randomized Phase 2 trial: Up to 4-year follow-up including patients without T315I mutations

Free
Qian Jiang, Zongru Li, Yanli Zhang, Yu Hu, Weiming Li, Yongping Song, Junmin Li, Li Zhou, Bingcheng LIU, Xiaoli Liu, Na Xu, Suning Chen, Zhenfang LIU, Huangling Zhu, Jie Jin, He Huang, Sixuan Qian, Li Meng, Xin Du, Xielan Zhao, Sujun Gao, Yang Liang, Ming Hou, Wei Wang, Zi Chen, Qian Niu, Lichuang Men, Dajun Yang, Yifan Zhai, Xiaojun Huang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3788.
https://doi.org/10.1182/blood-2025-3788
Published: 2025
Journal Articles

Nemtabrutinib in participants with relapsed or refractory follicular lymphoma: Updated efficacy and safety from cohort g of the phase 2 bellwave-003 study

Free
Wojciech Jurczak, Ana Basquiera, Isabelle Fleury, Sujun Gao, Arpad Illes, Andras Masszi, Antonio Pinto, Sanne Lugthart, Omur Sevindik, Iryna Kriachok, Elizabeth Phillips, Fei Li, Chan Cheah, Yan Xu, Mohammed Z.H. Farooqui, Jing Yang, Fangfang Lv
Journal: Blood
Blood (2025) 146 (Supplement 1): 3570.
https://doi.org/10.1182/blood-2025-3570
Published: 2025
Journal Articles

Primary analysis of a multicenter, open-label, phase 2 study of sonrotoclax (BGB-11417) monotherapy in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL)

Free
Shuhua Yi, Keshu Zhou, Ning Liu, Wei Sang, Rui Huang, Yi Wang, Chenghui Zhang, Fudao Wu, Ying Li, Mei Sun, Jian-Qing Mi, Kaiyang Ding, Sujun Gao, Qiaohua Zhang, Haiying Hua, Xiaoxia Chu, Jian Cheng, Aikebaier Abudureyimu, Lanyun Zhou, Cheryl Chow, Tianlei Chen, Zhiyu Liang, Remus Vezan, Lugui Qiu
Journal: Blood
Blood (2025) 146 (Supplement 1): 5666.
https://doi.org/10.1182/blood-2025-5666
Published: 2025
Journal Articles

Long-term treatment continuation of gecacitinib in myelofibrosis patients after ruxolitinib failure

Free
Yi Zhang, Hu Zhou, Qike Zhang, Qingchi Liu, Sujun Gao, Zhijian Xiao, Minghui Duan, Liangming Ma, Wei WANG, Huibing Dang, Guangsheng He, Hongmei Jing, Junmin Li, Haiping Yang, Huanling Zhu, Chunkang Chang, Yuqing Chen, Xin Du, Mei Hong, Xin Li, Jishi Wang, Na Xu, Peng Zhao, Shanshan Suo, Jie Jin
Journal: Blood
Blood (2025) 146 (Supplement 1): 5584.
https://doi.org/10.1182/blood-2025-5584
Published: 2025
Journal Articles

Quality-Adjusted Time without Symptoms of Disease or Toxicity (Q-TWiST) of Ponatinib Versus Imatinib, Administered in Combination with Reduced-Intensity Chemotherapy, in Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Free
Ajibade Ashaye, Ling Shi, Ibrahim Aldoss, Pau Montesinos, Pankit Vachhani, Cristina Papayannidis, Jessica T. Leonard, Maria R. Baer, Josep-Maria Ribera, James McCloskey, JianXiang Wang, Sujun Gao, Deepali Rane, Shien Guo
Journal: Blood
Blood (2024) 144 (Supplement 1): 2825.
https://doi.org/10.1182/blood-2024-208755
Published: 2024
Journal Articles

Intervention Therapy Based on MRD Detected By Flow Cytometry in Peripheral Blood during Early Induction Chemotherapy Could Improve the Remission Rate of Newly Diagnosed Acute Myeloid Leukemia

Free
Yehui Tan, Yanping Yang, Yuying Li, Sunyao Qi, Sujun Gao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6174.
https://doi.org/10.1182/blood-2024-205129
Published: 2024
Journal Articles

Hetrombopag Added to Immunosuppressive Therapy in First-Line Treatment of Severe Aplastic Anemia: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial

Free
Fengkui Zhang, Xin Zhao, Hong Chang, Bing Han, Sujun Gao, Miao Miao, Jianda Hu, Yanjuan Lin, Xinjian Liu, Lina Zhang, Chenghao Jin, Yingmei Li, Shengyun Lin, Jinsong Jia, Yi Wang, Chunkang Chang, Zheng Ge, Guangsheng He, Ruixiang Xia, Xiangjun Fu, Yuhua Li, Hong Liu, Kai Sun, Shunqing Wang, Linghui Xia, Weihua Zhang, Runzi Li, Junye Xiong, Wanyi Zhai
Journal: Blood
Blood (2024) 144 (Supplement 1): 304.
https://doi.org/10.1182/blood-2024-206377
Published: 2024
Journal Articles

A Novel JAK2 Inhibitor OB756 in Treatment of Janus Kinase Inhibitor-Naive Patients with Myelofibrosis: A Phase 1/2, Open-Label, Multicenter Study

Free
Yile Zhou, Jian Huang, Bingbing Wen, Hu Zhou, Wei Yang, Lianlian Fan, Tiejun Gong, Sujun Gao, Zongjiu Jiao, Qingchi Liu, Lidong Zhao, Guocai Wu, Cuicui Wu, Jun Wang, Jin Zhang, Jiaping Fu, Zengmei Sheng, Zunmin Zhu, Jian Lu, Yi Zhang, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1808.
https://doi.org/10.1182/blood-2024-212216
Published: 2024
Journal Articles

Post Hoc Analysis of Phase III Gecacitinib Clinical Trial Outcomes: Enhanced Understanding and Implications

Free
Yi Zhang, Hu Zhou, Shanshan Suo, Junling Zhuang, Linhua Yang, Aili He, Qingchi Liu, Xin Du, Sujun Gao, Yarong Li, Yan Li, Yuqing Chen, Wen Wu, Huanling Zhu, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Hongmei Jing, Jishi Wang, Na Xu, Lingling Yue, Cuiping Zheng, ZePing Zhou, Chenghao Jin, Xin Li, Lin Liu, Yajing Xu, Dengshu Wu, Feng Zhang, Jin Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2024-202790
Published: 2024
Journal Articles

A Phase II Study to Evaluate the Efficacy and Safety of Pimicotinib (ABSK021) in Chronic Graft Versus Host Disease (cGvHD) after 1 or More Lines of Systemic Treatment

Free
Xiaodong Mo, He Huang, Feng Chen, Yi Luo, Jia Chen, Erlie Jiang, Yicheng Zhang, Linghui Xia, Chengwei Luo Luo, Xinchuan Chen, Nainong Li, Ming Jiang, Sujun Gao, Dongqin Yang, Qingli Zuo, Yimin Chen, Li Yao, Pan Liang, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 99.
https://doi.org/10.1182/blood-2024-193191
Published: 2024
Journal Articles

Rovadicitinib in Patients with Myelofibrosis Who Were Refractory or Relapsed or Intolerant to Ruxolitinib: A Single Arm, Multicenter, Open-Label, Phase Ib Study

Free
Chunkang Chang, Min Zhang, Sujun Gao, Luxi Song, Duoer Wu, Dawei Ding, Shanli Lao, Ding Yu
Journal: Blood
Blood (2024) 144 (Supplement 1): 484.
https://doi.org/10.1182/blood-2024-203242
Published: 2024
Journal Articles

Comparison of Outcomes between Haploidentical and Matched Related Donors for Chronic Myelomonocytic Leukemia: A Multicenter Real-World Study

Free
Yuqian Sun, Lixin Wu, Yicheng Zhang, Ya-Jing Xu, Xiaobing Huang, Baodong Ye, Hailong Yuan, Jianying Zhou, Sujun Gao, Fang Zhou, Yue Liu, Xianmin Song, Yu Cai, Xiaoliang Liu, Yi Luo, Luxin Yang, Jianmin Yang, Libing Wang, Yuhua Li, Rui Huang, Shunqing Wang, Ming Zhou, Yujun Dong, Qian Wang, Yimei Feng, Xin Du, Wei Ling, Han Zhu, Zunmin Zhu, Xiangli Chen, Shiyun Wang, Fankai Meng, Kehong Bi, Ning Huang, Ming Jiang, Ting Niu, Jie Ji, Dingming Wan, Bian Zhilei, Yi Chen, Li Liu, Xueqian Yan, Xi Yang, Hai Yi, Xudong Wei, Xin Li, Qian Cheng, Chenglu Yuan, Wen Wang, Yuhong Zhou, Yu-Hong Chen, Fengrong WANG, YuanYuan Zhang, Zhi-Dong Wang, Xiao-Dong Mo, Wei Han, Jing-Zhi Wang, Yu Wang, Huan Chen, Xiangyu Zhao, Ying-jun Chang, Kaiyan Liu, Jia Feng, LanPing Xu, Hongyu Zhang, Xi Zhang, Xiaojun Huang, Xiaohui Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2187.
https://doi.org/10.1182/blood-2024-206919
Published: 2024
Journal Articles

Phase 1/2 Studies of DZD8586, a Non-Covalent BBB Penetrant LYN/BTK Dual Inhibitor, in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia (CLL) and Other B-Cell Non-Hodgkin Lymphoma (B-NHL)

Free
Yuqin Song, Keshu Zhou, Hongmei Jing, Geoffrey Chong, Jianqiu Wu, Wei Liu, Zengjun Li, Ming Jiang, Mei Lan, Kaiyang Ding, Guohui CUI, Tingyu Wang, Xutao Guo, Sujun Gao, Constantine S. Tam, Haiyan Yang, Fang Zhu, Wei Yang, Jian-Qing Mi, Liping Su, Ke Fang, Ziyi Liu, Lindsey Roeker, Chan Y. Cheah, Jianyong Li, Lu-Gui Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3248.
https://doi.org/10.1182/blood-2024-197877
Published: 2024
Journal Articles

Phase 2 Search Study：XPO1 Inhibitor (ATG-010) Monotherapy in Heavily Pretreated Chinese Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Qingyuan Zhang, Xiuhua Sun, Haiyan Yang, Zhihua Yao, Liqun Zou, Liling Zhang, Junning Cao, Tingyu Wang, Lanfang Li, Yao Liu, Hongmei Jing, Sujun Gao, Kaiyang Ding, Bingshan Liu, Jun Zhao, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6234.
https://doi.org/10.1182/blood-2023-180413
Published: 2023