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Journal Articles

Preliminary Efficacy and Safety of the CK1ε/PI3Kδ Dual Inhibitor HZ-H08905 in Patients with Relapsed and/or Refractory Peripheral T-Cell Lymphomas: Results from the Phase 1 HZ-H08905-101 Study

Free
Juying Wei, Wenjuan Yu, Zhengming Jin, Keshu Zhou, Haiyan Yang, Fei Li, Lanfang Li, Bo Zhang, Miao Hu, Yanping Zhang, Xinglu Zhou, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3057.
https://doi.org/10.1182/blood-2024-201210
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of the CK1ε/PI3Kδ Dual Inhibitor HZ-H08905 in Patients with Relapsed and/or Refractory B-Cell Lymphomas: Results from the Phase 1 HZ-H08905-101 Study

Free
Juying Wei, Wenjuan Yu, Zhengming Jin, Keshu Zhou, Haiyan Yang, Fei Li, Lanfang Li, Bo Zhang, Miao Hu, Yanping Zhang, Xinglu Zhou, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3015.
https://doi.org/10.1182/blood-2024-201190
Published: 2024
Journal Articles

Rocbrutinib, a New-Generation BTK Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Non-GCB Diffuse Large B Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3119.
https://doi.org/10.1182/blood-2024-194561
Published: 2024
Journal Articles

Phase 1/2 Studies of DZD8586, a Non-Covalent BBB Penetrant LYN/BTK Dual Inhibitor, in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia (CLL) and Other B-Cell Non-Hodgkin Lymphoma (B-NHL)

Free
Yuqin Song, Keshu Zhou, Hongmei Jing, Geoffrey Chong, Jianqiu Wu, Wei Liu, Zengjun Li, Ming Jiang, Mei Lan, Kaiyang Ding, Guohui CUI, Tingyu Wang, Xutao Guo, Sujun Gao, Constantine S. Tam, Haiyan Yang, Fang Zhu, Wei Yang, Jian-Qing Mi, Liping Su, Ke Fang, Ziyi Liu, Lindsey Roeker, Chan Y. Cheah, Jianyong Li, Lu-Gui Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3248.
https://doi.org/10.1182/blood-2024-197877
Published: 2024
Journal Articles

Spatial Multi-Omics Treatment Paradigms in a Phase II Clinical Study of Early Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Free
Meijuan Wu, Xi Chen, Jialiang Lu, Weihao Zhuang, Chang He, Cong Li, Haifeng Yu, Tao Lei, Xiaowu Dong, Jianpeng Sheng, Haiyan Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2996.
https://doi.org/10.1182/blood-2024-203388
Published: 2024
Journal Articles

Final Analysis of a Phase 1 Study of Zanubrutinib Plus Lenalidomide in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Free
Zheng Song, Ying Cheng, Haiyan Yang, Liling Zhang, Liqun Zou, Ye Guo, Junning Cao, Huiqiang Huang, Zhao Wang, Sha Huang, Yiqian Fang, Jiaoyan Lyu, Keshu Zhou, Huilai Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 986.
https://doi.org/10.1182/blood-2024-193167
Published: 2024
Journal Articles

Effectiveness and Safety of Polatuzumab Vedotin-Based Therapy for Diffuse Large B-Cell Lymphoma: Real-Life Experience from China

Free
Xi Chen, Haifeng Yu, Cong Li, Jieyu Xu, Tao Lei, Shuiyun Han, Shuailing Peng, Haiyan Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7782.
https://doi.org/10.1182/blood-2024-207832
Published: 2024
Journal Articles

Novel Combination Regimen Brentuximab Vedotin-Bege Achieves Remarkable Efficacy in Patients with Relapsed/Refractory Classical Hodgkin Lymphoma

Free
Xi Chen, Huilin Peng, Haifeng Yu, Cong Li, Tao Lei, Shuiyun Han, Shuailing Peng, Haiyan Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2024-207627
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of Bruton Tyrosine Kinase (BTK) Inhibitor HZ-a-018 in Adult Patients with Relapsed and/or Refractory (R/R) Central Nervous System Lymphoma or Treatment-Naïve (TN) Central Nervous System Lymphoma, Results from the Phase Ib Combination Part of HZ-a-018-102 Study

Free
Wenbin Li, Zhuang Kang, Feng Chen, Shenglan Li, Xi Chen, Xianggui Yuan, Haiyan Yang, Wenbin Qian, Miao Hu, Yanping Zhang, Xinglu Zhou
Journal: Blood
Blood (2024) 144 (Supplement 1): 6482.
https://doi.org/10.1182/blood-2024-201166
Published: 2024
Journal Articles

MBS303, a Novel 2:1 CD20×CD3 Bispecific Antibody, Demonstrated a Favorable Safety and Potent Antitumor Activity in Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma: Preliminary Results from a Phase Ⅰ, Dose-Escalation Trial

Free
Yuqin Song, Haiyan Yang, Youchao Jia, Lixia Sheng, Lijuan Deng, Xi Chen, Yongjing Tang, Xifang Liu, Sijun Liu, Min Wei, Feng Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 6481.
https://doi.org/10.1182/blood-2024-199342
Published: 2024
Journal Articles

Efficacy and Safety of Bendamustine, Pomalidomide, Sintilimab in Patients with Recurrent or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study

Free
Haiyan Yang, Shengsheng Zhou, Fengxiang Huang, Meiwei Li, Wenguang Bao, Man Wang, Dong Lan, Zhigang Peng
Journal: Blood
Blood (2024) 144 (Supplement 1): 6519.
https://doi.org/10.1182/blood-2024-204441
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of Bruton Tyrosine Kinase (BTK) Inhibitor HZ-a-018 in Adult Patients with Relapsed and/or Refractory(R/R)Central Nervous System Lymphoma, Results from the Phase Ia Monotherapy of HZ-a-018-102 Study

Free
Wenbin Li, Zhuang Kang, Feng Chen, Shenglan Li, Xi Chen, Xianggui Yuan, Haiyan Yang, Wenbin Qian, Miao Hu, Yanping Zhang, Xinglu Zhou
Journal: Blood
Blood (2024) 144 (Supplement 1): 6510.
https://doi.org/10.1182/blood-2024-201137
Published: 2024
Journal Articles

Safety and Efficacy of Rocbrutinib in Patients with Relapsed/Refractory Marginal Zone Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1635.
https://doi.org/10.1182/blood-2024-194572
Published: 2024
Journal Articles

Preclinical Study of a Novel USP28 Inhibitor for the Treatment of Burkitt Lymphoma

Free
Jieyu Xu, Shu Sun, Wen Gao, Pumin Zhang, Haiyan Yang, Honghu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 5838.
https://doi.org/10.1182/blood-2024-209311
Published: 2024
Journal Articles

Phase II, Single-Center, Prospective Study of Intrathecal Thiotepa for the Prophylaxis of Secondary Central Nervous System Involvement in Highly Aggressive B-Cell Lymphoma

Free
Cong Li, Tao Lei, Haifeng Yu, Xi Chen, Shuailing Peng, Shuiyun Han, Haiyan Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6227.
https://doi.org/10.1182/blood-2023-184694
Published: 2023
Journal Articles

A Prospective, Exploratory, Phase II Study of the Xpo-1 Inhibitor Selinexor in Combination with RCHOP in Double/Triple-Hit Large B-Cell Lymphoma

Free
Cong Li, Tao Lei, Haifeng Yu, Xi Chen, Shuailing Peng, Shuiyun Han, Haiyan Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6242.
https://doi.org/10.1182/blood-2023-184634
Published: 2023
Journal Articles

A Multicenter Phase2 Trial of Linperlisib in Relapsed or Refractory Peripheral T/NK Cell Lymphomas

Free
Yuqin Song, Zengjun Li, Huijing Wu, Jie Jin, Hui Zhou, Keshu Zhou, Liling Zhang, Zhigang Peng, Zhiye Zhang, Hong Cen, Youchao Jia, Yuerong Shuang, Zhiming Li, Haiyan Yang, Liqun Zou, Zhifeng Li, Zhihui Zhang, Junmin Li, Junning Cao, Lugui Qiu, Shaojie Wu, Tiejun Gong, Xiaohong Xu, Zhen Wang, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 306.
https://doi.org/10.1182/blood-2023-180137
Published: 2023
Journal Articles

Anti-Btla Antibody Tifcemalimab As a Single Agent or in Combination with Toripalimab in Relapsed/Refractory Lymphomas

Free
Yuqin Song, JUN MA, Yan Xie, Huilai Zhang, Zhigang Peng, Yuerong Shuang, Fei Li, Yufu Li, Haiyan Yang, Xiuhua Sun, Liqun Zou, Yunhong Huang, Weili Zhao, Wenrong Huang, Hui Zhou, Mingying Liu, Weiwei Wang, Jing Xu, Yajie Wang, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4458.
https://doi.org/10.1182/blood-2023-181385
Published: 2023
Journal Articles

A Phase Ib Open-Label Study of MRG001 in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)

Free
Jun Zhu, Yuqin Song, Ye Guo, Keshu Zhou, Wenyu Li, Yu Yang, Qingqing Cai, Zhao Wang, Haiyan Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3089.
https://doi.org/10.1182/blood-2023-189675
Published: 2023
Journal Articles

Safety and Efficacy Results from the Phase I Study of a Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2023-180694
Published: 2023