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Journal Articles

Rbm38 Deficiency Impairs Erythroid Heme Biosynthesis and Induces Porphyria via Reduced Ferrochelatase Expression

Blood blood.2025028783.

https://doi.org/10.1182/blood.2025028783

Published: 2025

Includes: Supplemental data

Journal Articles

Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study

Blood (2025) 145 (24): 2914–2926.

https://doi.org/10.1182/blood.2024027336

Published: 2025

Includes: Supplemental data

Journal Articles

Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy

Wei Liu, Xiaolei Pei, Bingqi Xu, Xinyue Dai, Feng Xue, Linging Chen, Yuhua Wang, Yunfei Chen, Xiaofan Liu, Rongfeng Fu, Wentian Wang, Ying Chi, Huiyuan Li, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 3583.

https://doi.org/10.1182/blood-2024-199915

Published: 2024

Journal Articles

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Feng Xue, Mankai Ju, Tienan Zhu, ZePing Zhou, Jing Sun, Linhua Yang, Zhenyu Yan, Hu Zhou, Xin Du, Changcheng Zheng, Xia Wu, Xiao Xiao, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 3582.

https://doi.org/10.1182/blood-2024-204715

Published: 2024

Journal Articles

Targeting PRMT9 Overcomes Venetoclax Resistance in AML By Modulating Splicing and Inhibiting Translation

Yang Li, Xin He, Haojie Dong, Lei Zhang, Umesh Yadav, Meng Liu, Lianjun Zhang, Guido Marcucci, Shaoyuan Wang, Ling Li

Blood (2024) 144 (Supplement 1): 54.

https://doi.org/10.1182/blood-2024-203923

Published: 2024

Journal Articles

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Wei Liu, Hu Zhou, Ruibin Huang, Xin Du, ZePing Zhou, Changcheng Zheng, Shifeng Lou, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 1213.

https://doi.org/10.1182/blood-2024-199149

Published: 2024

Journal Articles

Strikingly Reduced Toxicities of Fotemustine-Based Chemotherapeutics Than High-Dose Methotrexate-Containing Regimens with Comparable Efficacy

Blood (2024) 144 (Supplement 1): 6458.

https://doi.org/10.1182/blood-2024-202107

Published: 2024

Journal Articles

A First-in-Human Dose Escalation Clinical Trial of Engineered Natural Killer Cell Therapy in Non-Small Cell Lung Cancer Patients Refractory to Immune Check Point Inhibitors

Miguel A Villalona, Lei Tian, Xiaochen Li, Joycelynne Michelle Palmer, Claudia Aceves, Hans Meisen, Catherine Cortez, Tim W Synold, Colt Egelston, Jeffery Vandeusen, Ivone Bruno, Lei Zhang, Eliezer Romeu-Bonilla, Omer Butt, Stephen J. Forman, Michael A Caligiuri, Jianhua Yu

Blood (2024) 144 (Supplement 1): 7206.

https://doi.org/10.1182/blood-2024-202132

Published: 2024

Journal Articles

Optimized Recombinant Human Thrombopoietin(rhTPO) Regimen Versus Eltrombopag for Pre-Treated Patients with Primary Immune Thrombocytopenia: Interim Results from a Prospective, Multicenter, Randomized Trial (TE-ITP study)

Yunfei Chen, Ting Sun, Da Gao, Wei Wang, ZePing Zhou, Guangxun Gao, Yi Wang, Hu Zhou, Yanping Song, Yinghui Lai, Zhenyu Yan, Jinsong Yan, Jie Bai, Lei Zhang

Blood (2024) 144 (Supplement 1): 3937.

https://doi.org/10.1182/blood-2024-202716

Published: 2024

Journal Articles

Artificial Intelligence-Based Quantitative Bone Marrow Pathology Analysis for Myeloproliferative Neoplasms

Dandan Yu, Hong-Ju Zhang, Yanyan Song, Yuan Tao, Fengyuan Zhou, Ziyi Wang, Rongfeng Fu, Ting Sun, Huan Dong, Wenjing Gu, Renchi Yang, Zhijian Xiao, Qi Sun, Lei Zhang

Blood (2024) 144 (Supplement 1): 3182.

https://doi.org/10.1182/blood-2024-201265

Published: 2024

Journal Articles

Targeting Cytidine Triphosphate Synthase 1 Promotes Anti-AML Immunity

Meng Liu, Lei Zhang, Haojie Dong, Xin He, Yang Li, Umesh Yadav, Guido Marcucci, Ling Li

Blood (2024) 144 (Supplement 1): 3590.

https://doi.org/10.1182/blood-2024-203905

Published: 2024

Journal Articles

Efficacy and Safety of Oral Bruton Tyrosine Kinase Inhibitor (BTKi) Rilzabrutinib in Adults with Previously Treated Immune Thrombocytopenia (ITP): A Phase 3, Placebo-Controlled, Parallel-Group, Multicenter Study (LUNA 3)

Blood (2024) 144 (Supplement 1): 5.

https://doi.org/10.1182/blood-2024-199718

Published: 2024

Journal Articles

TGF-β1 Reverses Hemoglobin Switching in Erythroid Progenitor Cells before Erythropoietin Induction

Wentian Wang, Yuanyuan Tuo, Yuchen Gao, Qianyu Huo, Jiaying Liu, Lei Zhang, Ying Chi, Huiyuan Li, Xiaolei Pei, Zhixu He

Blood (2024) 144 (Supplement 1): 2474.

https://doi.org/10.1182/blood-2024-204590

Published: 2024

Journal Articles

Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia

Yu Yang, Huiyuan Li, Xiaofan Liu, Hong Wang, Lei Zhang, Renchi Yang

Blood (2024) 144 (Supplement 1): 2553.

https://doi.org/10.1182/blood-2024-203209

Published: 2024

Journal Articles

Proteomics and Single-Cell Transcriptomics Reveal Differentiation Patterns of pDC-like LSCs and Poor Prognosis in AML with pDC Expansion

Xingcheng Yang, Juan Peng, Lei Zhang, Yicheng Zhang, Xia Mao, Jue Wang, Jia Wei

Blood (2024) 144 (Supplement 1): 2935.

https://doi.org/10.1182/blood-2024-202707

Published: 2024

Journal Articles

High HDAC8 Creates Targetable Vulnerabilities in Acute Myeloid Leukemia through Dysregulation of BRCA1-Related RNA Splicing Machinery and Defective DNA Damage Repair

Lianjun Zhang, Yu-Hsuan Fu, Wei-Kai Hua, Le Xuan Truong Nguyen, Xin He, Wancheng Guo, Yinghui Zhu, Ying-Chieh Chen, Zhenhua Chen, Haojie Dong, Lei Zhang, Bin Zhang, Jeremy Stark, Ling Li, Guido Marcucci, Ya-Huei Kuo

Blood (2024) 144 (Supplement 1): 1398.

https://doi.org/10.1182/blood-2024-208137

Published: 2024

Journal Articles

Identification of Metabolic Biomarkers Associated with the Efficacy of Intravenous Immunoglobulin in the Treatment of Immune Thrombocytopenia Based on Machine Learning

Yang Li, Chen Jia, Ting Sun, Yunfei Chen, Lei Zhang

Blood (2024) 144 (Supplement 1): 5442.

https://doi.org/10.1182/blood-2024-205473

Published: 2024

Journal Articles

A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia

Rongfeng Fu, Xiaofan Liu, Xinmiao Qu, Feng Xue, Wei Liu, Yunfei Chen, Ting Sun, Mankai Ju, Huan Dong, Wenjing Gu, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 5438.

https://doi.org/10.1182/blood-2024-204932

Published: 2024

Journal Articles

A Novel F12 Gene Pathogenic Mutation Identified in a Consanguineous Pedigree with Clustered Thrombotic and Pulmonary Disease

Xinmiao Qu, Xiaofan Liu, Rongfeng Fu, Yujiao Jia, Yuhua Wang, Feng Xue, Wei Liu, Yunfei Chen, Ting Sun, Mankai Ju, Huan Dong, Wenjing Gu, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 5558.

https://doi.org/10.1182/blood-2024-202375

Published: 2024

Journal Articles

Outcomes and Prognostic Factors of the Alternative Regimens for Angioimmunoblastic T Cell Lymphoma: A Retrospective Study

Jiaqin Yan, Bingjie Wang, Yankui Wei, Shasha Zhang, Lei Zhang, Ling Li, Xin Li, Xiaorui Fu, Xinhua Wang, Zhenchang Sun, Xudong Zhang, Mingzhi Zhang

Blood (2024) 144 (Supplement 1): 6408.

https://doi.org/10.1182/blood-2024-206732

Published: 2024

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Rbm38 Deficiency Impairs Erythroid Heme Biosynthesis and Induces Porphyria via Reduced Ferrochelatase Expression

Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study

Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Targeting PRMT9 Overcomes Venetoclax Resistance in AML By Modulating Splicing and Inhibiting Translation

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Strikingly Reduced Toxicities of Fotemustine-Based Chemotherapeutics Than High-Dose Methotrexate-Containing Regimens with Comparable Efficacy

A First-in-Human Dose Escalation Clinical Trial of Engineered Natural Killer Cell Therapy in Non-Small Cell Lung Cancer Patients Refractory to Immune Check Point Inhibitors

Optimized Recombinant Human Thrombopoietin(rhTPO) Regimen Versus Eltrombopag for Pre-Treated Patients with Primary Immune Thrombocytopenia: Interim Results from a Prospective, Multicenter, Randomized Trial (TE-ITP study)

Artificial Intelligence-Based Quantitative Bone Marrow Pathology Analysis for Myeloproliferative Neoplasms

Targeting Cytidine Triphosphate Synthase 1 Promotes Anti-AML Immunity

Efficacy and Safety of Oral Bruton Tyrosine Kinase Inhibitor (BTKi) Rilzabrutinib in Adults with Previously Treated Immune Thrombocytopenia (ITP): A Phase 3, Placebo-Controlled, Parallel-Group, Multicenter Study (LUNA 3)

TGF-β1 Reverses Hemoglobin Switching in Erythroid Progenitor Cells before Erythropoietin Induction

Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia

Proteomics and Single-Cell Transcriptomics Reveal Differentiation Patterns of pDC-like LSCs and Poor Prognosis in AML with pDC Expansion

High HDAC8 Creates Targetable Vulnerabilities in Acute Myeloid Leukemia through Dysregulation of BRCA1-Related RNA Splicing Machinery and Defective DNA Damage Repair

Identification of Metabolic Biomarkers Associated with the Efficacy of Intravenous Immunoglobulin in the Treatment of Immune Thrombocytopenia Based on Machine Learning

A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia

A Novel F12 Gene Pathogenic Mutation Identified in a Consanguineous Pedigree with Clustered Thrombotic and Pulmonary Disease

Outcomes and Prognostic Factors of the Alternative Regimens for Angioimmunoblastic T Cell Lymphoma: A Retrospective Study

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