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Journal Articles

Targeting Deacetylase Sirt-1 Reprograms Treg Function in Immune Thrombocytopenia

Yu Hou, Haoyi Wang, Mingfang Zhu, Heyu Ni, Ming Hou
Journal: Blood
Blood (2024) 144 (Supplement 1): 2548.
https://doi.org/10.1182/blood-2024-202842
Published: 2024
Journal Articles

Sirolimus Combined Dexamethasone As the First-Line Therapy for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Multicenter, Open-Label, Prospective, Randomized Controlled Clinical Trial

Yimei Feng, Hanqing Zeng, Yi Liao, Yi Yang, Wenzheng Yu, Changyong Yuan, Guojun Li, Zhanshu Liu, Huae Shu, Guoxiang Zhang, Yaqing Feng, Chunfang Peng, Xiaoli Chen, Jia Liu, Han Yao, Ming Hou, Xi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1187.
https://doi.org/10.1182/blood-2024-207041
Published: 2024
Journal Articles

Subgroup Analyses of Phase 2 Study: Evaluating the Efficacy of Fully Human BCMA-Targeting CAR T Cells (Zevorcabtagene Autoleucel) in Patients with Relapsed/Refractory Multiple Myeloma

Wenming Chen, Chengcheng Fu, Baijun Fang, Aibin Liang, Zhongjun Xia, Yanjuan He, Jin Lu, Hui Liu, Ming Hou, Zhen Cai, Wei Yang, Siguo Hao, Songfu Jiang, Hongmei Jing, Jing Liu, Xin Du, Rong Fu, Heng Mei, Zunmin Zhu, Yanli Yang, Hong Liu, Xingxing Meng, Nishanthan Rajakumaraswamy, Wei Zheng, Huamao Wang, Zonghai Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 4762.
https://doi.org/10.1182/blood-2024-204620
Published: 2024
Journal Articles

Weekly Selinexor, Bortizomib and Dexamethasone (SVd) Versus Twice Weekly Bortizomib and Dexamethasone (Vd) in Chinese Patients with Relapsed and Refractory Multiple Myeloma (RRMM): Primary Analysis of Phase 3 Bench Study

Jin Lu, Liangquan Geng, Lijuan Chen, Peng Liu, Yuping Zhong, Zhuogang Liu, Zhongjun Xia, Jianqing Mi, Chunrui Li, Xi Zhang, Yanjuan He, Yongqiang Wei, Baijun Fang, Fei Li, Zhen Cai, Yafei Wang, Dongping Huang, Hong Liu, Ming Hou, Rong Fu, Xin Du, Xiaosheng Fang, Qingshu Zeng, Wen Gao, Wei Wang, Chunkang Chang, Guifang Ouyang, Jing Liu, Jianyu Weng, Xiaobing Huang, Yang Yu, Zhi Guo, Jun Zhao, Jian Hou
Journal: Blood
Blood (2024) 144 (Supplement 1): 4748.
https://doi.org/10.1182/blood-2024-202893
Published: 2024
Journal Articles

Ponatinib 2-Year Efficacy, Safety and Health-Related Quality of Life in Patients with Philadelphia Chromosome-Positive Leukemia: An Open-Label, Multicenter, Phase 2 Clinical Trial in China

Lu Yu, Huifang Wang, Xiaoli Liu, Bingcheng Liu, Xielan Zhao, Qun He, Qingshu Zeng, Zimin Sun, Ting Liu, Huanling Zhu, Zhuogang Liu, Xin Du, Jie Jin, Li Meng, Ming Hou, Suning Chen, Linhua Yang, Mingji Xian, Yoshitaka Kotobuki, Shuang Zhang, Qian Jiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6602.
https://doi.org/10.1182/blood-2024-208258
Published: 2024
Journal Articles

Eltrombopag plus diacerein vs eltrombopag in patients with ITP: a multicenter, randomized, open-label phase 2 trial

Clinical Trials & Observations
Lu Sun, Xiaoyang Huang, Juan Wang, Chenglu Yuan, Hongyu Zhao, Daqi Li, Ruirong Xu, Yan Wang, Ping Qin, Yan Shi, Jun Peng, Ming Hou, Yu Hou
Journal: Blood
Blood (2024) 144 (17): 1791–1799.
https://doi.org/10.1182/blood.2024025067
Published: 2024
Includes: Supplemental data
Journal Articles

Platelet-derived TGF-β1 induces functional reprogramming of myeloid-derived suppressor cells in immune thrombocytopenia

Lingjun Wang, Haoyi Wang, Mingfang Zhu, Xiaofei Ni, Lu Sun, Wanru Wang, Jie Xie, Yubin Li, Yitong Xu, Ruting Wang, Shouqing Han, Ping Zhang, Jun Peng, Ming Hou, Yu Hou
Journal: Blood
Blood (2024) 144 (1): 99–112.
https://doi.org/10.1182/blood.2023022738
Published: 2024
Includes: Supplemental data
Journal Articles

Recommendations on Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia Treated with Combination of All- Trans Retinoic Acid and Arsenic Trioxide

Li Chen, Hongming Zhu, Fangyi Dong, Yan Li, Qifa Liu, Yu Hu, Yicheng Zhang, Jie Jin, Jianda Hu, Ting Liu, Depei Wu, Jieping Chen, Yongrong Lai, Jianxiang Wang, Juan Li, Jianyong Li, Xin Du, Xin Wang, Mingzhen Yang, Jinsong Yan, Guifang Ouyang, Li Liu, Ming Hou, Xiaojun Huang, Wen Jin, Yongmei Zhu, Jian Li, Kankan Wang, Zhu Chen, Sai-Juan Chen, Junmin Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2023-184433
Published: 2023
Journal Articles

Platelet-Derived TGF-β1 Induces Functional Reprogramming of Myeloid-Derived Suppressor Cells in Immune Thrombocytopenia

Yu Hou, Lingjun Wang, Haoyi Wang, Lu Sun, Ruting Wang, Yubin Li, Ming Hou
Journal: Blood
Blood (2023) 142 (Supplement 1): 2562.
https://doi.org/10.1182/blood-2023-182619
Published: 2023
Journal Articles

The Therapeutic Efficacy of CD19 Chimeric Antigen Receptor T Cells in Immune Thrombocytopenia Model

Yun Wang, Fengjiao Han, Qiuyu Guo, Qi Feng, Jun Peng, Ming Hou, Miao Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 688.
https://doi.org/10.1182/blood-2023-178649
Published: 2023
Journal Articles

Olverembatinib (HQP1351) Demonstrates Efficacy Vs. Best Available Therapy (BAT) in Patients (Pts) with Tyrosine Kinase Inhibitor (TKI)-Resistant Chronic Myeloid Leukemia Chronic-Phase (CML-CP) in a Registrational Randomized Phase 2 Study

Qian Jiang, Zongru Li, Gongli Zhang, Yu Hu, Weiming Li, Yongping Song, Junmin Li, Li Zhou, Bingcheng Liu, Xiaoli Liu, Na Xu, Suning Chen, Zhenfang Liu, Huanling Zhu, Jie Jin, He Huang, Sixuan Qian, Li Meng, Xin Du, Xielan Zhao, Sujun Gao, Yang Liang, Ming Hou, Wei Wang, Zi Chen, Qian Niu, Lichuang Men, Dajun Yang, Yifan Zhai, Xiaojun Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 869.
https://doi.org/10.1182/blood-2023-187740
Published: 2023
Journal Articles

A Single Institutional Experience Using Avatrombopag to Manage Severe and Refractory Treatment Related Thrombocytopenia in Solid Tumor and Hematologic Malignancy Patients

Linlin Shao, Lu Liu, Yu Hou, Xiaolin Zhang, Lin Wang, Shuqian Xu, Ping Qin, Qiang Song, Jun Peng, Ming Hou, Yan Shi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5447.
https://doi.org/10.1182/blood-2023-188831
Published: 2023
Journal Articles

The Proactive Diagnostic Value of Thrombin-Antithrombin Complex and Antithrombin III in Disseminated Intravascular Coagulation

Qiuyu Guo, Fengjiao Han, Jun Peng, Ming Hou, Tichao Shan, Miao Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1268.
https://doi.org/10.1182/blood-2023-178993
Published: 2023
Journal Articles

Efficacy and Safety of Clifutinib, a Novel, Highly Selective, Oral FLT3 Inhibitor, in Patients with FLT3-Mutated Relapsed or Refractory Acute Myeloid Leukemia：Updated Results from a Phase I Study

Jie Jin, Huafeng Wang, Wen-Juan Yu, Zheng Ge, Xudong Wei, Yuhua Li, Zhongxing Jiang, Yiqing Li, Xin Du, Linhua Yang, Lie Lin, Jishi Wang, Yazhou Yao, Xiaoping Hu, Jianping Lan, Xiuzhi Deng, Tong Chen, Xianqi Feng, Dengju Li, Ming Hou, Rong Fu, Siyong Huang, Jingbo Wang, Xin Du, Hui Yang, Haiping Yang, Yingzhi Jiang, Zhijie Wang, Deng Li, Bing Liu, Ning Kang, Yulei Zhuang, Yingjun Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2023-188961
Published: 2023
Journal Articles

The Role of Gpibα in Control of Megakaryocyte Reactivity to Thrombopoietin

Fengjiao Han, Qiuyu Guo, Yun Wang, Zihan Zhang, Qi Feng, Jun Peng, Ming Hou, Heyu Ni, Miao Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1219.
https://doi.org/10.1182/blood-2023-179047
Published: 2023
Journal Articles

The Lack of Tolerable Treatments Options That Can Induce Durable Responses without Fear of Relapse after Discontinuation Represents a Significant Unmet Need for Patients (Pts) with Immune Thrombocytopenia (ITP): Results from the ITP World Impact Survey (I-WISh) 2.0

James B. Bussel, Nichola Cooper, Waleed Ghanima, Drew Provan, Yoshiaki Tomiyama, Ming Hou, Donald Arnold, Cristina Santoro, Francesco Zaja, Barbara Lovrencic, Mervyn Morgan, Leron Lahav, Michal Winograd, Jennifer MacWhirter - DiRaimo, Tom Bailey, Moyra Aziz, Roberto Abi Rached, Caroline Kruse
Journal: Blood
Blood (2023) 142 (Supplement 1): 1212.
https://doi.org/10.1182/blood-2023-188527
Published: 2023
Journal Articles

Low-dose decitabine modulates myeloid-derived suppressor cell fitness via LKB1 in immune thrombocytopenia

Xiaofei Ni, Lingjun Wang, Haoyi Wang, Tianshu Yu, Jie Xie, Guosheng Li, Yanfeng Liu, Hai Zhou, Miao Xu, Ming Hou, Jun Peng, Yu Hou
Journal: Blood
Blood (2022) 140 (26): 2818–2834.
https://doi.org/10.1182/blood.2022016029
Published: 2022
Includes: Supplemental data
Journal Articles

Switching from Eltrombopag to Hetrombopag in Patients with Primary Immune Thrombocytopenia (ITP): Post-Hoc Analysis of a Multicenter, Randomized Phase III Trial

Yu Hu, Renchi Yang, Ting Niu, Heng Mei, Liu Xiaofan, Yan Li, Hu Zhou, Ying Feng, Guangxun Gao, Peng Cheng, Ruibin Huang, Linhua Yang, Jianda Hu, Ming Hou, Yazhou Yao, Li Liu, Yi Wang, De-Pei Wu, Xuliang Shen, Jie Jin, Jianmin Luo, Zeng Yun, Xin Zhou, Ruixiang Xiang, Zhongxing Jiang, Yuansong Bai, Junye Xiong, Runzi Li, Jianjun Zou
Journal: Blood
Blood (2022) 140 (Supplement 1): 5543–5545.
https://doi.org/10.1182/blood-2022-162945
Published: 2022
Journal Articles

Eltrombopag Plus Diacerein Versus Eltrombopag in Adult Primary Immune Thrombocytopenia: Interim Analysis of a Multicenter, Randomized, Controlled, Phase 2 Trial

Lu Sun, Ping Qin, Ruirong Xu, Juandong Wang, Hongyu Zhao, Yan Wang, Juan Wang, Xin Wang, Yu Hou, Ming Hou
Journal: Blood
Blood (2022) 140 (Supplement 1): 8410–8411.
https://doi.org/10.1182/blood-2022-165239
Published: 2022
Journal Articles

Rapamycin Inhibits Cytotoxic T Lymphocytes-Mediated Platelet Destruction in Immune Thrombocytopenia

Xiaofei Ni, Yajing Zhao, Tianshu Yu, Haoyi Wang, Lingjun Wang, Pengcheng Xu, Hai Zhou, Yanfeng Liu, Xinguang Liu, Yu Hou, Jihua Qiu, Ming Hou
Journal: Blood
Blood (2022) 140 (Supplement 1): 8404–8405.
https://doi.org/10.1182/blood-2022-166345
Published: 2022