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Journal Articles

Deficiency of neutrophil gelatinase-associated lipocalin elicits Hemophilia-like bleeding and clotting disorder

Min Xue, Shaoying Wang, Changjiang Li, Yuewei Wang, Ming Liu, Xiaoshan Huang, Gan Wang, Qikai Yin, Dandan Xiao, Shuo Yang, Musan Yan, Liyuan Niu, Muhammad Awais, Chuanbin Shen, Jianxun Wang, Ren Lai, Heyu Ni, Xiaopeng Tang

Blood blood.2024026476.

https://doi.org/10.1182/blood.2024026476

Published: 2024

Includes: Supplemental data

Journal Articles

Targeting Deacetylase Sirt-1 Reprograms Treg Function in Immune Thrombocytopenia

Yu Hou, Haoyi Wang, Mingfang Zhu, Heyu Ni, Ming Hou

Blood (2024) 144 (Supplement 1): 2548.

https://doi.org/10.1182/blood-2024-202842

Published: 2024

Journal Articles

The Role of Gpibα in Control of Megakaryocyte Reactivity to Thrombopoietin

Fengjiao Han, Qiuyu Guo, Yun Wang, Zihan Zhang, Qi Feng, Jun Peng, Ming Hou, Heyu Ni, Miao Xu

Blood (2023) 142 (Supplement 1): 1219.

https://doi.org/10.1182/blood-2023-179047

Published: 2023

Journal Articles

Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

Blood (2022) 140 (19): 2063–2075.

https://doi.org/10.1182/blood.2022016410

Published: 2022

Includes: Supplemental data

Journal Articles

Snake Venom Botrocetin Induces GPIb-Independent Platelet Aggregation

Chuanbin Shen, Daniel Mackeigan, Guangheng Zhu, Miguel A. D. Neves, Wenjing Ma, Eric Cerenzia, Heyu Ni

Blood (2021) 138 (Supplement 1): 4203.

https://doi.org/10.1182/blood-2021-152314

Published: 2021

Journal Articles

Thiol Isomerase Activity of β 3 Integrin Psi Domain and L33P Polymorphism: Implications in Blood Coagulation and Anti-Thrombotic Therapy

Eric Gaetano Cerenzia, Tyler W. Stratton, Daniel Mackeigan, Zhenze Liu, Guangheng Zhu, Xi Lei, Preeti Bhoria, Heyu Ni

Blood (2021) 138 (Supplement 1): 1052.

https://doi.org/10.1182/blood-2021-151294

Published: 2021

Journal Articles

Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells

Danielle Karakas, June Li, Heyu Ni

Blood (2021) 138 (Supplement 1): 3139.

https://doi.org/10.1182/blood-2021-145985

Published: 2021

Journal Articles

Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model

Xiuzhang Xu, Dawei Chen, Xin Ye, Wenjie Xia, Yaori Xu, Yangkai Chen, Yuan Shao, Jing Deng, Haoqiang Ding, Jing Liu, Jiali Wang, Heyu Ni, Yongshui Fu, Sentot Santoso

Blood (2021) 138 (18): 1757–1767.

https://doi.org/10.1182/blood.2021011131

Published: 2021

Includes: Supplemental data

Journal Articles

Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fcγ receptor inhibition

Peter A. A. Norris, Gurleen Kaur, Ramsha Khan, Guangheng Zhu, Heyu Ni, Alan H. Lazarus

Blood (2021) 137 (15): 2114–2124.

https://doi.org/10.1182/blood.2020009497

Published: 2021

Includes: Supplemental data

Journal Articles

The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation

Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai

Blood (2020) 136 (8): 974–988.

https://doi.org/10.1182/blood.2019002314

Published: 2020

Includes: Supplemental data

Journal Articles

Alpha-Dystroglycan Supports Platelet Aggregation and Thrombus Formation

Yiming Wang, MD PhD, Reid C. Gallant, MSc, Miguel A. D. Neves, PhD MSc, Xi Lei, MSc, Sahil Gupta, MSc, Rodrigo Coelho, BSc, Tatianna Wong, MSc, Ronald D. Cohn, MD, Kevin P. Campbell, PhD, Heyu Ni, MD MSc, PhD

Blood (2019) 134 (Supplement_1): 11.

https://doi.org/10.1182/blood-2019-131521

Published: 2019

Journal Articles

Coenzyme Q10 Attenuates Platelet Integrin αIIbβ3 Outside-in Signaling through Targeting cAMP/PKA Pathway and Inhibits Atherosclerosis

Yan Yang, MD PhD, Xiaohong Ruby Xu, MD PhD, Heyu Ni, MD MSc, PhD, Liping Ma, MD, Wenhua Ling, Fuli Ya

Blood (2018) 132 (Supplement 1): 2423.

https://doi.org/10.1182/blood-2018-99-120196

Published: 2018

Journal Articles

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

Tyler W. Stratton, MSc, Guangheng Zhu, MD, Yiming Wang, MD PhD, Pingguo Chen, PhD, Miguel A. D. Neves, PhD MSc, Reid C. Gallant, MSc, Peter A. A. Norris, BSc, John J. Freedman, MD, Heyu Ni, MD MSc, PhD

Blood (2018) 132 (Supplement 1): 1246.

https://doi.org/10.1182/blood-2018-99-119964

Published: 2018

Journal Articles

GPIbα is required for platelet-mediated hepatic thrombopoietin generation

Miao Xu, June Li, Miguel Antonio Dias Neves, Guangheng Zhu, Naadiya Carrim, Ruoying Yu, Sahil Gupta, John Marshall, Ori Rotstein, Jun Peng, Ming Hou, Shinji Kunishima, Jerry Ware, Donald R. Branch, Alan H. Lazarus, Zaverio M. Ruggeri, John Freedman, Heyu Ni

Blood (2018) 132 (6): 622–634.

https://doi.org/10.1182/blood-2017-12-820779

Published: 2018

Includes: Supplemental data

Journal Articles

Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents

Xiaohong Ruby Xu, George M. Yousef, Heyu Ni

Blood (2018) 131 (16): 1777–1789.

https://doi.org/10.1182/blood-2017-05-743187

Published: 2018

Includes: Supplemental data

Journal Articles

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets

M. Edward Quach, Matthew A. Dragovich, Wenchun Chen, Anum K. Syed, Wenpeng Cao, Xin Liang, Wei Deng, Simon F. De Meyer, Guangheng Zhu, Jun Peng, Heyu Ni, Carolyn M. Bennett, Ming Hou, Jerry Ware, Hans Deckmyn, X. Frank Zhang, Renhao Li

Blood (2018) 131 (7): 787–796.

https://doi.org/10.1182/blood-2017-05-784975

Published: 2018

Includes: Supplemental data

Journal Articles

Multimerin-1 Binds to Specific Motifs in Vessel Wall Collagens and Contributes to Thrombosis: Novel Insights Regarding the Mechanisms That Support Human and Mouse Platelet Adhesion

Alexander Leatherdale, BA, D'Andra Parker, PhD, Subia Tasneem, Yiming Wang, PhD, Arkadiusz Bonna, PhD MSc, Peter L. Gross, MD, Heyu Ni, MD MSc, PhD, Bradley Doble, PhD, Richard W. Farndale, MA, PhD, Catherine P.M. Hayward, MD

Blood (2017) 130 (Supplement 1): 549.

https://doi.org/10.1182/blood.V130.Suppl_1.549.549

Published: 2017

Journal Articles

Erythrocyte-Specific Antibodies As a Potential New Therapeutic Modality in Autoimmune and Inflammatory Disorders Beyond Immune Thrombocytopenia (ITP)

Andrew R Crow, BRT, Rick Kapur, MDPhDMSc, Mark Jen, MSc, Patrick J Mott, MSc, Danielle Marjoram, MSc, Alaa Amash, PhD, Simrat S Kahlon, BSc, Issaka Yougbare, PhD, Heyu Ni, MD MSc, PhD, Michael Kim, BSc, John W Semple, PhD, Alan H Lazarus, PhD

Blood (2017) 130 (Supplement 1): 231.

https://doi.org/10.1182/blood.V130.Suppl_1.231.231

Published: 2017

Journal Articles

Antibodies Against Macrophage CD44 Protect Platelets from FcγR-Mediated Phagocytosis: A Potential Mechanism for CD44 Antibody Amelioration of Murine Immune Thrombocytopenia

Peter A A Norris, BSc, Yawen Wang, MD, Guangheng Zhu, MD, Lin Wang, MD, Ming Huo, MD, Gregory D Fairn, PhD, Heyu Ni, MD MSc, PhD, Alan H Lazarus, PhD

Blood (2017) 130 (Supplement 1): 3639.

https://doi.org/10.1182/blood.V130.Suppl_1.3639.3639

Published: 2017

Journal Articles

Maternal Anti-αIIb Antibodies Target Fetal Hematopoietic Stem Cells and May Lead to Pancytopenia and Miscarriage in Fnait

Jade Sullivan, BSc, Brigitta Elaine Oswald, B.Sc, Brian Vadasz, BSc, June Li, MSc, Pingguo Chen, PhD, Mortimer Poncz, MD, John J. Freedman, MD, Heyu Ni, MD MSc, PhD

Blood (2017) 130 (Supplement 1): 233.

https://doi.org/10.1182/blood.V130.Suppl_1.233.233

Published: 2017

NARROW

Deficiency of neutrophil gelatinase-associated lipocalin elicits Hemophilia-like bleeding and clotting disorder

Targeting Deacetylase Sirt-1 Reprograms Treg Function in Immune Thrombocytopenia

The Role of Gpibα in Control of Megakaryocyte Reactivity to Thrombopoietin

Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

Snake Venom Botrocetin Induces GPIb-Independent Platelet Aggregation

Thiol Isomerase Activity of β 3 Integrin Psi Domain and L33P Polymorphism: Implications in Blood Coagulation and Anti-Thrombotic Therapy

Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells

Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model

Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fcγ receptor inhibition

The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation

Alpha-Dystroglycan Supports Platelet Aggregation and Thrombus Formation

Coenzyme Q10 Attenuates Platelet Integrin αIIbβ3 Outside-in Signaling through Targeting cAMP/PKA Pathway and Inhibits Atherosclerosis

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

GPIbα is required for platelet-mediated hepatic thrombopoietin generation

Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets

Multimerin-1 Binds to Specific Motifs in Vessel Wall Collagens and Contributes to Thrombosis: Novel Insights Regarding the Mechanisms That Support Human and Mouse Platelet Adhesion

Erythrocyte-Specific Antibodies As a Potential New Therapeutic Modality in Autoimmune and Inflammatory Disorders Beyond Immune Thrombocytopenia (ITP)

Antibodies Against Macrophage CD44 Protect Platelets from FcγR-Mediated Phagocytosis: A Potential Mechanism for CD44 Antibody Amelioration of Murine Immune Thrombocytopenia

Maternal Anti-αIIb Antibodies Target Fetal Hematopoietic Stem Cells and May Lead to Pancytopenia and Miscarriage in Fnait

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American Society of Hematology

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ASH Publications

American Society of Hematology

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