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Journal Articles

Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children

Kristin A. Shimano, Amanda B. Grimes, Melissa J Rose, Shipra Kaicker, Sanjay J. Shah, Michael Briones, Elizabeth Gunn, Taizo A. Nakano, Jeffrey D Lebensburger, Michele P. Lambert, Stephanie A. Fritch Lilla, Rohith Jesudas, Cathy A. Lee-Miller, Alexis Thompson, Rukhmi Bhat, Stacey Rifkin-Zenenberg, Suvankar Majumdar, Manpreet Kochhar, Shelley E Crary, Kerry Hege, Jennifer A. Rothman, James B. Ford, Joshua J Bies, John Fort, Loan Hsieh, Maritza E. Ruiz, Kathryn M. Carrier, Bogdan Dinu, Julia MW Wong, Pei-Chi Kao, Wendy B. London, Staci D. Arnold, Carolyn M. Bennett, Jenny Despotovic, Robert J. Klaassen, Ellis J. Neufeld, Cindy E Neunert, Rachael F. Grace
Journal: Blood
Blood (2024) 144 (Supplement 1): 709.
https://doi.org/10.1182/blood-2024-193644
Published: 2024
Journal Articles

mTOR inhibition attenuates cTfh cell dysregulation and chronic T-cell activation in multilineage immune cytopenias

Brief Report
Deepak Kumar, Thinh H. Nguyen, Carolyn M. Bennett, Chengyu Prince, Laura Lucas, Sunita Park, Taylor Lawrence, Karin Chappelle, Mariam Ishaq, Edmund K. Waller, Sampath Prahalad, Michael Briones, Shanmuganathan Chandrakasan
Journal: Blood
Blood (2023) 141 (3): 238–243.
https://doi.org/10.1182/blood.2022015966
Published: 2023
Includes: Supplemental data
Journal Articles

T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome

Deepak Kumar, Chengyu Prince, Carolyn M. Bennett, Michael Briones, Laura Lucas, Athena Russell, Kiran Patel, Satheesh Chonat, Sara Graciaa, Holly Edington, Michael H. White, Lisa Kobrynski, Manar Abdalgani, Suhag Parikh, Sharat Chandra, Jack Bleesing, Rebecca Marsh, Sunita Park, Edmund K. Waller, Sampath Prahalad, Shanmuganathan Chandrakasan
Journal: Blood
Blood (2022) 139 (3): 369–383.
https://doi.org/10.1182/blood.2021012924
Published: 2022
Includes: Supplemental data
Journal Articles

Standardizing the Diagnostic and Therapeutic Approach to Newly Diagnosed Children with ITP: An ITP Consortium of North America (ICON) Quality Improvement Initiative

Alexander W. Rankin, Sherif M. Badawy, Carolyn M. Bennett, Taylah Buissereth, Kristen Campbell, Hannah Elkus, Rachael F. Grace, Allison Remiker, Stacey Rifkin, Taizo A. Nakano
Journal: Blood
Blood (2021) 138 (Supplement 1): 755.
https://doi.org/10.1182/blood-2021-146936
Published: 2021
Journal Articles

Introducing a Novel Biophysical Platelet Function Panel to Investigate Disorders of Primary Hemostasis and Bleeding of Unknown Cause

Sally Azer, Oluwamayokun Oshinowo, Meredith E. Fay, Yumiko Sakurai, Yongzhi Qiu, Carolyn M. Bennett, Shannon Meeks, Megan C. Brown, David R. Myers, Wilbur A. Lam
Journal: Blood
Blood (2021) 138 (Supplement 1): 2072.
https://doi.org/10.1182/blood-2021-153324
Published: 2021
Journal Articles

A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children

Kristin A. Shimano, MD, Rachael F. Grace, MD, Carolyn M. Bennett, MDMSc, Robert J Klaassen, MD FRCPC, Cindy Neunert, MD, Ellis J. Neufeld, MD, Clement Ma, PhD, Wendy B. London, PhD, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2369.
https://doi.org/10.1182/blood-2019-125487
Published: 2019
Journal Articles

Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia

Oluwamayokun T. Oshinowo, BS, Renee Copeland, BS, Christina Caruso, MD, Meredith E. Fay, BS, Traci Leong, PhD, Carolyn M. Bennett, MDMSc, Wilbur A. Lam, MD PhD, David R. Myers, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1096.
https://doi.org/10.1182/blood-2019-129573
Published: 2019
Journal Articles

Early Prophylaxis Provides Continued Joint Protection in Severe Hemophilia A: Results of the Joint Outcome Continuation Study

Beth Boulden Warren, MD MS, Dianne Thornhill, PhD, Jill Stein, MD, Michael Fadell, MD, Sharon Funk, DPT, Heidi D. Lane, DPT, Carolyn M. Bennett, MD MSc, Amy Shapiro, Michael Recht, MD PhD, Marilyn J Manco-Johnson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 382.
https://doi.org/10.1182/blood-2018-99-117413
Published: 2018
Journal Articles

Platelet Contraction Force As a Biophysical Biomarker for Bleeding Risk in Patients with Immune Thrombocytopenia

Oluwamayokun T. Oshinowo, Renee Copeland, BS, Carolyn M. Bennett, MD MSc, Wilbur A Lam, MD PhD, David R. Myers, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 517.
https://doi.org/10.1182/blood-2018-99-115292
Published: 2018
Journal Articles

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets

M. Edward Quach, Matthew A. Dragovich, Wenchun Chen, Anum K. Syed, Wenpeng Cao, Xin Liang, Wei Deng, Simon F. De Meyer, Guangheng Zhu, Jun Peng, Heyu Ni, Carolyn M. Bennett, Ming Hou, Jerry Ware, Hans Deckmyn, X. Frank Zhang, Renhao Li
Journal: Blood
Blood (2018) 131 (7): 787–796.
https://doi.org/10.1182/blood-2017-05-784975
Published: 2018
Includes: Supplemental data
Journal Articles

Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)

Rachael F. Grace, MD, Robert J Klaassen, MD FRCPC, Rukhmi Bhat, MDMS, Michelle Neier, MD, Melissa J. Rose, DO, Jenny M. Despotovic, DO, MS, Carolyn M. Bennett, MD MSc, James B. Bussel, MD, Jennifer A. Rothman, MD, Vicky R. Breakey, BSc,MDFRCPC, Kerry Hege, MD, Kristin A. Shimano, MD, Kristina M. Haley, DO, Amy E. Geddis, MD, George R. Buchanan, MD, Adonis Lorenzano, MD, Cindy Neunert, MD, Michael R. Jeng, MD, Yves D. Pastore, MD, Shelley Crary, MD MS, Ellis J Neufeld, MD PhD, Nolan Neu, BS, Peter Forbes, BS, Michele P. Lambert, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 752.
https://doi.org/10.1182/blood.V130.Suppl_1.752.752
Published: 2017
Journal Articles

Platelet Contraction Cytometry: A Biophysical, High-Throughput Research-Enabling and Diagnostic Platform

Oluwamayokun T. Oshinowo, Aaron W. Lam, Benjamin Brainard, VMD, Dipl ACVAA, ACVECC, Carolyn M. Bennett, MD MSc, Wilbur A. Lam, MDPhD, David R. Myers, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2301.
https://doi.org/10.1182/blood.V130.Suppl_1.2301.2301
Published: 2017
Journal Articles

Outcomes of Immunosuppressive Therapy for Pediatric Aplastic Anemia: A North American Pediatric Aplastic Anemia Consortium (NAPAAC) Study

Zora R. Rogers, MD, Taizo Allen Nakano, MD, Timothy S. Olson, MD PhD, Alison A. Bertuch, MD PhD, Anjulika Chawla, MD, Paul Castillo, MD, Winfred Wang, MD, Alfred Gillio, MD, Grzegorz Nalepa, MD PhD, Peter Kurre, MD, Carolyn M. Bennett, MD MSc, Rabi Hanna, MD, Christopher Gamper, Gary M. Kupfer, MD, Jennifer A. Rothman, MD, Jessica Boklan, MD, Alexis A Thompson, MD MPH, Amy E. Geddis, MD, Bertil Glader, MD, James N. Huang, MD, Thomas D. Coates, MD, Michaela Cada, MD FRCPC, FAAP, MPH, Kelly J. Walkovich, MD, Sarita Joshi, MBBS,MD, Adrianna Vlachos, MD, Edie A. Weller, David A. Williams, MD, Akiko Shimamura, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1168.
https://doi.org/10.1182/blood.V130.Suppl_1.1168.1168
Published: 2017
Journal Articles

Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study

Rachael F Grace, MD, Robert J. Klaassen, MD, Jennifer A Rothman, MD, Kerry Hege, MD, Ellis J Neufeld, MD PhD, Carolyn M. Bennett, Michele Lambert, MD, Vicky R. Breakey, BSc, MD MD FRCPC, James B. Bussel, MD, George R. Buchanan, MD, Melissa J. Rose, DO, Amy Geddis, MD PhD, Kristin Shimano, MD, Kristina M. Haley, DO, Adonis Lorenzana, MD, Cindy Neunert, MD, Alexis A. Thompson, MD MPH, Yves D. Pastore, MD, Michael Jeng, MD, Shelley E. Crary, MD MSCS, Michelle Neier, MD, Travis Brown, Peter Forbes, BS, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2016) 128 (22): 249.
https://doi.org/10.1182/blood.V128.22.249.249
Published: 2016
Journal Articles

Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP

Michele P. Lambert, MD MTR, Rachael F Grace, MD, Cindy Neunert, MD, Jenny M. Despotovic, DO, MS, Rukhmi Bhat, MDMS, Yves D. Pastore, MD, George R. Buchanan, MD, Robert J. Klaassen, MD, Carolyn M. Bennett, Jennifer A Rothman, MD, Vicky R. Breakey, BSc, MD MD FRCPC, James B. Bussel, MD, Melissa J. Rose, DO, Amy Geddis, MD PhD, Kristin Shimano, MD, Kerry Hege, MD, Kristina M. Haley, DO, Adonis Lorenzana, MD, Michael Jeng, MD, Shelley E. Crary, MD MSCS, Michelle Neier, MD, Travis Brown, Peter Forbes, BS, Ellis J Neufeld, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1008.
https://doi.org/10.1182/blood.V128.22.1008.1008
Published: 2016
Journal Articles

Long Term Safety and Efficacy of Recombinant Factor IX Fc Fusion Protein (rFIXFc) Prophylaxis in Children with Hemophilia B: Interim Results of the B-Yond Extension Study

Jonathan M. Ducore, Kathelijn Fischer, Roshni Kulkarni, MD, Beatrice Nolan, Carolyn M. Bennett, David J Perry, Huixing Yuan, Alejandra Ramirez-Santiago, Francesca Ferrante, Stefan Lethagen
Journal: Blood
Blood (2016) 128 (22): 4976.
https://doi.org/10.1182/blood.V128.22.4976.4976
Published: 2016
Journal Articles

Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study

Breakey R. Vicky, MD MD FRCPC, Rachael F Grace, MD, Carolyn M. Bennett, Jenny M. Despotovic, DO, MS, Jennifer A Rothman, MD, Yves D. Pastore, MD, Ellis J Neufeld, MD PhD, Robert J. Klaassen, MD, Michele Lambert, MD, James B. Bussel, MD, George R. Buchanan, MD, Melissa J. Rose, DO, Amy E. Geddis, MD PhD, Kristin Shimano, MD, Kerry Hege, MD, Kristina M. Haley, DO, Adonis Lorenzana, MD, Alexis A. Thompson, MD MPH, Michael Jeng, MD, Shelley E. Crary, MD MSCS, Michelle Neier, MD, Travis Brown, Peter Forbes, BS, Cindy Neunert, MD
Journal: Blood
Blood (2016) 128 (22): 4752.
https://doi.org/10.1182/blood.V128.22.4752.4752
Published: 2016
Journal Articles

Genes Influencing the Development and Severity of Chronic ITP Identified through Whole Exome Sequencing

Jenny M. Despotovic, DO, MS, Linda M. Polfus, PhD, Jonathan M. Flanagan, PhD, Carolyn M. Bennett, Michele P Lambert, MD, Cindy Neunert, MD, Manjusha Kumar, MD, Robert J. Klaassen, MD FRCP, Courtney Thornburg, MD MS, Michael Jeng, MD, Michael Recht, MD PhD, Susan E. Kirk, PA-C, Alexis A. Thompson, MD, Diane J. Nugent, MD, Ellis J. Neufeld, MD PhD, James B. Bussel, MD, Eric Boerwinkle, PhD, Rachael F. Grace, MD
Journal: Blood
Blood (2015) 126 (23): 73.
https://doi.org/10.1182/blood.V126.23.73.73
Published: 2015
Journal Articles

Clinical Outcomes in Children with Hemophilia B Treated Long Term with rFIXFc: Interim Results of the B-YOND Extension Study

Roshni Kulkarni, Beatrice Nolan, Carolyn M. Bennett, Kathelijn Fischer, David J Perry, Christopher Barnes, Huixing Yuan, Alejandra Ramirez-Santiago, Glenn F Pierce, Baisong Mei
Journal: Blood
Blood (2015) 126 (23): 1093.
https://doi.org/10.1182/blood.V126.23.1093.1093
Published: 2015
Journal Articles

Validation Study Of The Composite Score To Identify Von Willebrand Disease in Children

Lynn M. Malec, MD, Charity G. Moore, MSPH, PhD, Carolyn M. Bennett, MD, MS, Donald L Yee, MD, Bryce A. Kerlin, MD, Char Witmer, MD, Sriya Gunawardena, MD, Roshni Kulkarni, MD, Sweta Gupta, MBBS, MD, Peter A. Kouides, MD, Deborah Brown, Heather L. Bujnicki, MD, Margaret V. Ragni, MD, MPH
Journal: Blood
Blood (2013) 122 (21): 2356.
https://doi.org/10.1182/blood.V122.21.2356.2356
Published: 2013