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Journal Articles

Transplant Related Outcomes in Patients with Hemophagocytic Lymphohistiocytosis Treated with Emapalumab As a Bridge to Hematopoietic Stem Cell Transplantation: The Real-HLH Study

Carl E Allen, Shanmuganathan Chandrakasan, Michael B. Jordan, Jennifer W Leiding, Michael Marrone, Abiola Oladapo, Priti Pednekar, Kelly J. Walkovich, John Yee

Blood (2024) 144 (Supplement 1): 3489.

https://doi.org/10.1182/blood-2024-204680

Published: 2024

Journal Articles

Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD

Jennifer W. Leiding, Danielle E. Arnold, Suhag Parikh, Brent Logan, Rebecca A. Marsh, Linda M. Griffith, Ruizhe Wu, Sharon Kidd, Kanwaldeep Mallhi, Deepak Chellapandian, Stephanie J. Si Lim, Eyal Grunebaum, E. Liana Falcone, Luis Murguia-Favela, Debbi Grossman, Vinod K. Prasad, Jennifer R. Heimall, Fabien Touzot, Lauri M. Burroughs, Jack Bleesing, Neena Kapoor, Jasmeen Dara, Olatundun Williams, Malika Kapadia, Benjamin R. Oshrine, Jeffrey J. Bednarski, Ahmad Rayes, Hey Chong, Geoffrey D. E. Cuvelier, Lisa R. Forbes Satter, Caridad Martinez, Mark T. Vander Lugt, Lolie C. Yu, Shanmuganathan Chandrakasan, Avni Joshi, Susan E. Prockop, Blachy J. Dávila Saldaña, Victor Aquino, Larisa A. Broglie, Christen L. Ebens, Lisa M. Madden, Kenneth DeSantes, Jordan Milner, Hemalatha G. Rangarajan, Ami J. Shah, Alfred P. Gillio, Alan P. Knutsen, Holly K. Miller, Theodore B. Moore, Pamela Graham, Andrea Bauchat, Nancy J. Bunin, Pierre Teira, Aleksandra Petrovic, Sharat Chandra, Hisham Abdel-Azim, Morna J. Dorsey, Olga Birbrayer, Morton J. Cowan, Christopher C. Dvorak, Elie Haddad, Donald B. Kohn, Luigi D. Notarangelo, Sung-Yun Pai, Jennifer M. Puck, Michael A. Pulsipher, Troy R. Torgerson, Harry L. Malech, Elizabeth M. Kang

Blood (2023) 142 (24): 2105–2118.

https://doi.org/10.1182/blood.2022019586

Published: 2023

Includes: Supplemental data

Journal Articles

Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis

Jenny Shim, Sunita Park, Suresh Venkateswaran, Deepak Kumar, Chengyu Prince, Vaunita Parihar, Larkin Maples, Edmund K. Waller, Subra Kugathasan, Michael Briones, Miyoung Lee, Curtis J. Henry, Sampath Prahalad, Shanmuganathan Chandrakasan

Blood (2023) 142 (23): 1972–1984.

https://doi.org/10.1182/blood.2023020426

Published: 2023

Includes: Supplemental data

Journal Articles

Real-World Treatment Patterns and Outcomes Among Patients with Secondary Hemophagocytic Lymphohistiocytosis Treated with Emapalumab in the United States: The Real-HLH Study

Carl E Allen, Shanmuganathan Chandrakasan, Michael B. Jordan, Jennifer W Leiding, Abiola Oladapo, Priti Pednekar, Kelly Walkovich, John Yee

Blood (2023) 142 (Supplement 1): 3909.

https://doi.org/10.1182/blood-2023-186948

Published: 2023

Journal Articles

Real-World Treatment Patterns and Outcomes Among Patients with Primary Hemophagocytic Lymphohistiocytosis with and without Infection at Diagnosis and Treated with Emapalumab: The Real-HLH Study

Carl E Allen, Shanmuganathan Chandrakasan, Michael B. Jordan, Jennifer W Leiding, Abiola Oladapo, Priti Pednekar, Kelly Walkovich, John Yee

Blood (2023) 142 (Supplement 1): 2534.

https://doi.org/10.1182/blood-2023-181777

Published: 2023

Journal Articles

mTOR inhibition attenuates cTfh cell dysregulation and chronic T-cell activation in multilineage immune cytopenias

Deepak Kumar, Thinh H. Nguyen, Carolyn M. Bennett, Chengyu Prince, Laura Lucas, Sunita Park, Taylor Lawrence, Karin Chappelle, Mariam Ishaq, Edmund K. Waller, Sampath Prahalad, Michael Briones, Shanmuganathan Chandrakasan

Blood (2023) 141 (3): 238–243.

https://doi.org/10.1182/blood.2022015966

Published: 2023

Includes: Supplemental data

Journal Articles

Real-World Demographics, Clinical Characteristics, and Treatment Patterns of Patients Treated with Emapalumab for Primary Hemophagocytic Lymphohistiocytosis in the United States: The Real-HLH Study

Carl E. Allen, Shanmuganathan Chandrakasan, Michael B Jordan, Jennifer W Leiding, Abiola Oladapo, Priti Pednekar, Kelly J. Walkovich, John Yee

Blood (2022) 140 (Supplement 1): 2595–2596.

https://doi.org/10.1182/blood-2022-166649

Published: 2022

Journal Articles

Pediatric Evans Syndrome Displays Broad Immune Dysregulation Characterized By Extra-Follicular B-Cell Responses and Unique Autoantibody Repertoire

Deepak Kumar, Chengyu Prince, Tyler Hulett, Pedro Ramos, Oscar Candelario, Laura Youngblood, Michael Briones, Carolyn Bennett, Shanmuganathan Chandrakasan

Blood (2022) 140 (Supplement 1): 1646–1647.

https://doi.org/10.1182/blood-2022-169527

Published: 2022

Journal Articles

HLA-DR + CD38 high Expression in T Cells Is Excellent in Quantifying the Amplitude of T-Cell Activation in a Spectrum of Hyperinflammatory Disorders Including HLH

Thinh H Nguyen, Deepak Kumar, Chengyu Prince, Michael Briones, Shanmuganathan Chandrakasan

Blood (2022) 140 (Supplement 1): 8329–8330.

https://doi.org/10.1182/blood-2022-170987

Published: 2022

Journal Articles

Lentiviral Gene Therapy with Low Dose Conditioning for X-Linked SCID Results in Complete Immune Reconstitution and No Evidence of Clonal Expansion

Blood (2022) 140 (Supplement 1): 7770–7771.

https://doi.org/10.1182/blood-2022-159979

Published: 2022

Journal Articles

Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC

Geoffrey D. E. Cuvelier, Brent R. Logan, Susan E. Prockop, Rebecca H. Buckley, Caroline Y. Kuo, Linda M. Griffith, Xuerong Liu, Alison Yip, Michael S. Hershfield, Paul G. Ayoub, Theodore B. Moore, Morna J. Dorsey, Richard J. O’Reilly, Neena Kapoor, Sung-Yun Pai, Malika Kapadia, Christen L. Ebens, Lisa R. Forbes Satter, Lauri M. Burroughs, Aleksandra Petrovic, Deepak Chellapandian, Jennifer Heimall, David C. Shyr, Ahmad Rayes, Jeffrey J. Bednarski, Sharat Chandra, Shanmuganathan Chandrakasan, Alfred P. Gillio, Lisa Madden, Troy C. Quigg, Emi H. Caywood, Blachy J. Dávila Saldaña, Kenneth DeSantes, Hesham Eissa, Frederick D. Goldman, Jacob Rozmus, Ami J. Shah, Mark T. Vander Lugt, Monica S. Thakar, Roberta E. Parrott, Caridad Martinez, Jennifer W. Leiding, Troy R. Torgerson, Michael A. Pulsipher, Luigi D. Notarangelo, Morton J. Cowan, Christopher C. Dvorak, Elie Haddad, Jennifer M. Puck, Donald B. Kohn

Blood (2022) 140 (7): 685–705.

https://doi.org/10.1182/blood.2022016196

Published: 2022

Includes: Supplemental data

Journal Articles

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

Christopher Ronald Funk, Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar, Vikas A. Gupta, Shanmuganathan Chandrakasan, Jaquelyn T. Zoine, Andrew Fedanov, Sunil S. Raikar, Jean L. Koff, Christopher R. Flowers, Silvia Coma, Jonathan A. Pachter, Sruthi Ravindranathan, H. Trent Spencer, Mala Shanmugam, Edmund K. Waller

Blood (2022) 139 (4): 523–537.

https://doi.org/10.1182/blood.2021011597

Published: 2022

Includes: Supplemental data

Journal Articles

T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome

Blood (2022) 139 (3): 369–383.

https://doi.org/10.1182/blood.2021012924

Published: 2022

Includes: Supplemental data

Journal Articles

Real-World Treatment Patterns and Outcomes in Patients with Hemophagocytic Lymphohistiocytosis (HLH) and Other Clinical Conditions Treated with Emapalumab: The Real-HLH Study Design

Carl E. Allen, Jennifer Leiding, Shanmuganathan Chandrakasan, Kelly J. Walkovich, Abiola Oladapo, John Yee, Priti Pednekar, Sajjad Raza, Michael B Jordan

Blood (2021) 138 (Supplement 1): 4991.

https://doi.org/10.1182/blood-2021-148555

Published: 2021

Journal Articles

Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies

Blood (2021) 137 (3): 349–363.

https://doi.org/10.1182/blood.2020007292

Published: 2021

Includes: Supplemental data

Journal Articles

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Lauri M. Burroughs, Aleksandra Petrovic, Ruta Brazauskas, Xuerong Liu, Linda M. Griffith, Hans D. Ochs, Jack J. Bleesing, Stephanie Edwards, Christopher C. Dvorak, Sonali Chaudhury, Susan E. Prockop, Ralph Quinones, Frederick D. Goldman, Troy C. Quigg, Shanmuganathan Chandrakasan, Angela R. Smith, Suhag Parikh, Blachy J. Dávila Saldaña, Monica S. Thakar, Rachel Phelan, Shalini Shenoy, Lisa R. Forbes, Caridad Martinez, Deepak Chellapandian, Evan Shereck, Holly K. Miller, Neena Kapoor, Jessie L. Barnum, Hey Chong, David C. Shyr, Karin Chen, Rolla Abu-Arja, Ami J. Shah, Katja G. Weinacht, Theodore B. Moore, Avni Joshi, Kenneth B. DeSantes, Alfred P. Gillio, Geoffrey D. E. Cuvelier, Michael D. Keller, Jacob Rozmus, Troy Torgerson, Michael A. Pulsipher, Elie Haddad, Kathleen E. Sullivan, Brent R. Logan, Donald B. Kohn, Jennifer M. Puck, Luigi D. Notarangelo, Sung-Yun Pai, David J. Rawlings, Morton J. Cowan

Blood (2020) 135 (23): 2094–2105.

https://doi.org/10.1182/blood.2019002939

Published: 2020

Journal Articles

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

Blood (2018) 132 (20): 2115–2124.

https://doi.org/10.1182/blood-2018-07-862334

Published: 2018

Includes: Supplemental data

Journal Articles

Early B Cell Development Is Impaired in Patients with Active Hemophagocytic Lymphohistiocytosis

Jenny Shim, MD, Sunita Park, MD, Shanmuganathan Chandrakasan, MD

Blood (2017) 130 (Supplement 1): 1006.

https://doi.org/10.1182/blood.V130.Suppl_1.1006.1006

Published: 2017

Journal Articles

Day 100 Levels of Blood Immune Cells Are Prognostic Biomarkers for Allogeneic Hematopoietic Stem Cell Transplant Outcomes: Results from BMT CTN 0201

Shanelle M. Fernando, Brent R. Logan, PhD, Mingwei Fei, MS, Stephanie J. Lee, MD PhD, Dennis Confer, MD, Alan Howard, PhD, Shanmuganathan Chandrakasan, MD, Cynthia R. Giver, PhD, Claudio Anasetti, MD, Edmund K. Waller, MD

Blood (2017) 130 (Supplement 1): 516.

https://doi.org/10.1182/blood.V130.Suppl_1.516.516

Published: 2017

Journal Articles

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG /NEMO mutations

Blood (2017) 130 (12): 1456–1467.

https://doi.org/10.1182/blood-2017-03-771600

Published: 2017

Includes: Supplemental data

NARROW

Transplant Related Outcomes in Patients with Hemophagocytic Lymphohistiocytosis Treated with Emapalumab As a Bridge to Hematopoietic Stem Cell Transplantation: The Real-HLH Study

Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD

Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis

Real-World Treatment Patterns and Outcomes Among Patients with Secondary Hemophagocytic Lymphohistiocytosis Treated with Emapalumab in the United States: The Real-HLH Study

Real-World Treatment Patterns and Outcomes Among Patients with Primary Hemophagocytic Lymphohistiocytosis with and without Infection at Diagnosis and Treated with Emapalumab: The Real-HLH Study

mTOR inhibition attenuates cTfh cell dysregulation and chronic T-cell activation in multilineage immune cytopenias

Real-World Demographics, Clinical Characteristics, and Treatment Patterns of Patients Treated with Emapalumab for Primary Hemophagocytic Lymphohistiocytosis in the United States: The Real-HLH Study

Pediatric Evans Syndrome Displays Broad Immune Dysregulation Characterized By Extra-Follicular B-Cell Responses and Unique Autoantibody Repertoire

HLA-DR + CD38 high Expression in T Cells Is Excellent in Quantifying the Amplitude of T-Cell Activation in a Spectrum of Hyperinflammatory Disorders Including HLH

Lentiviral Gene Therapy with Low Dose Conditioning for X-Linked SCID Results in Complete Immune Reconstitution and No Evidence of Clonal Expansion

Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome

Real-World Treatment Patterns and Outcomes in Patients with Hemophagocytic Lymphohistiocytosis (HLH) and Other Clinical Conditions Treated with Emapalumab: The Real-HLH Study Design

Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

Early B Cell Development Is Impaired in Patients with Active Hemophagocytic Lymphohistiocytosis

Day 100 Levels of Blood Immune Cells Are Prognostic Biomarkers for Allogeneic Hematopoietic Stem Cell Transplant Outcomes: Results from BMT CTN 0201

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG /NEMO mutations

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American Society of Hematology

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American Society of Hematology

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