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Sruthi Ravindranathan
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Journal Articles

Modulating the Vasoactive Intestinal Peptide (VIP) Pathway Reprograms Superior CAR T Cells

Heather K. Lin, Dejah Blake, Kory Wells, Ruby Freeman, Abhijay Mudigonda, William Liu, Alysa N Evans, Subir Goyal, Tongrui Liu, Christopher Ronald Funk, Tanisha Sinha, Elyse Christensen, Naeman Mahmood, Fan Fei, Brad Heller, Paul Chun, Tenzin Passang, Sruthi Ravindranathan, Jodi Dougan, Christopher C. Porter, Chrystal Paulos, Anupam Patgiri, Lily Yang, Edmund K. Waller, Sarwish Rafiq
Journal: Blood
Blood (2024) 144 (Supplement 1): 7154.
https://doi.org/10.1182/blood-2024-208090
Published: 2024
Journal Articles

Antagonizing Vasoactive Intestinal Peptide (VIP) Receptors on CAR T Cells Improves Efficacy and Persistence

Heather Lin, Dejah Blake, Abhijay Mudigonda, Alysa N Evans, Ruby Freeman, Tanisha Sinha, Fan Fei, Elyse Christensen, Tenzin Passang Fnu, Sruthi Ravindranathan, Tongrui Liu, Lily Yang, Edmund K. Waller, Sarwish Rafiq
Journal: Blood
Blood (2023) 142 (Supplement 1): 4806.
https://doi.org/10.1182/blood-2023-182952
Published: 2023
Journal Articles

Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression

Jingru Zhu, Yitong Wang, Jingxia Li, Pankoj Kumar Das, Hanwen Zhang, Tenzin Passang, Jian Ming Li, Tamas Nagy, Khanjan Gandhi, Sruthi Ravindranathan, Cynthia R. Giver, Mojibade Hassan, Yiwen Li, Alina Ulezko Antonova, Shuhua Wang, John D. Roback, Edmund K. Waller
Journal: Blood
Blood (2022) 140 (12): 1431–1447.
https://doi.org/10.1182/blood.2021012561
Published: 2022
Includes: Supplemental data
Journal Articles

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

Christopher Ronald Funk, Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar, Vikas A. Gupta, Shanmuganathan Chandrakasan, Jaquelyn T. Zoine, Andrew Fedanov, Sunil S. Raikar, Jean L. Koff, Christopher R. Flowers, Silvia Coma, Jonathan A. Pachter, Sruthi Ravindranathan, H. Trent Spencer, Mala Shanmugam, Edmund K. Waller
Journal: Blood
Blood (2022) 139 (4): 523–537.
https://doi.org/10.1182/blood.2021011597
Published: 2022
Includes: Supplemental data
Journal Articles

Inhibition of Vasoactive Intestinal Peptide Signaling with More Potent Inhibitors Augments T-Cell Activation and Prolongs Survival in Leukemic Mice

Tenzin Passang Fnu, Jianming Li, Sruthi Ravindranathan, Edmund K. Waller
Journal: Blood
Blood (2021) 138 (Supplement 1): 1868.
https://doi.org/10.1182/blood-2021-151879
Published: 2021
Journal Articles

PI3K δ /γ Inhibition Enhances the Expansion and Anti-Tumor Cytotoxicity of CART Cells for CLL Patients

Shuhua Wang, Christopher R. Funk, Sruthi Ravindranathan, Kevin Chen, Edmund K. Waller
Journal: Blood
Blood (2021) 138 (Supplement 1): 4795.
https://doi.org/10.1182/blood-2021-152163
Published: 2021
Journal Articles

Donor Plasmacytoid Dendritic Cells Regulate GvHD in a VIP Dependent Manner in Allogeneic BMT Recipients

Jingru Zhu, Pankoj Kumar Das, Yitong Wang, Jingxia Li, Tamas Nagy, Khajan Ghandhi, Sruthi Ravindranathan, Cynthia R. Giver, Jian-Ming Li, Yiwen Li, Alina Ulezko Antonova, John D Roback, Shuhua Wang, Edmund K. Waller
Journal: Blood
Blood (2021) 138 (Supplement 1): 1687.
https://doi.org/10.1182/blood-2021-152945
Published: 2021