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Sunil S. Raikar
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Journal Articles

Ancestral L-Asparaginases Are Cytotoxic Against ALL Cell Lines with Predicted Reduced Immunogenicity

Kristopher Adrian Knight, Harrison C. Brown, Mathew S. Karpen, H. Trent Spencer, Christopher B. Doering, Sunil S Raikar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4169.
https://doi.org/10.1182/blood-2024-205342
Published: 2024
Journal Articles

Obesity Attenuates CAR T-Cell Function in Pediatric B-Cell Acute Lymphoblastic Leukemia

Jessica Maaskant, Anthony J Ross, Karmella A Haynes, Alysa N Evans, Emily C Sullivan, Elizabeth P Weinzerl, Heather Lin, Dejah Blake, Liora Michal Schultz, Sunil S Raikar, Sarwish Rafiq, Curtis J Henry
Journal: Blood
Blood (2024) 144 (Supplement 1): 4807.
https://doi.org/10.1182/blood-2024-212050
Published: 2024
Journal Articles

CAR-Machine: CAR-T Cell Target Identification Platform for Pediatric Acute Leukemia and Implementation to Identify Novel Targets for Pediatric AML

Hope L Mumme, Siddhartha Mantrala, Chenbin Huang, Denis Ohlstrom, Sarthak Satpathy, Swati Bhasin, Sunil S Raikar, Manoj Bhasin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4302.
https://doi.org/10.1182/blood-2024-210175
Published: 2024
Journal Articles

Nelarabine Is Active in Pediatric T/Myeloid Mixed Phenotype Acute Leukemia

Ryan J Summers, Hope L Mumme, Anjali Khanna, Manoj Bhasin, Tamara P. Miller, Sunil S Raikar
Journal: Blood
Blood (2024) 144 (Supplement 1): 5902.
https://doi.org/10.1182/blood-2024-205142
Published: 2024
Journal Articles

Preclinical Evaluation of Combination Allogeneic Gamma Delta (γδ) T Cell Therapy with Azacitidine and Venetoclax for T-Cell Acute Lymphoblastic Leukemia

Gianna M. Branella, Brandon J. Fanelli, Areeba A. Hashmi, Emily C Sullivan, Sunil S Raikar
Journal: Blood
Blood (2024) 144 (Supplement 1): 7191.
https://doi.org/10.1182/blood-2024-205762
Published: 2024
Journal Articles

Real-World Performance of 2022 Revised World Health Organization (WHO) Criteria for Mixed Phenotype Acute Leukemia (MPAL) B/Myeloid Defined Only By Isolated MPO Expression (isoMPO)

Alexandra E. Kovach, Sunil S. Raikar, Jemily Malvar, Matthew J. Oberley, Gerald Wertheim, Karen R. Rabin, Jyotinder N. Punia, Alix Seif, Reuven J. Schore, Dragos C. Luca, Terri L. Guinipero, William G. Woods, Viviane Cahen, Yueh-Yun Chi, Maurice R.G. O'Gorman, Brent L. Wood, Etan Orgel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1467.
https://doi.org/10.1182/blood-2023-174110
Published: 2023
Journal Articles

Development of a Novel L-Asparaginase with Enhanced Properties Using Ancestral Sequence Reconstruction

Kristopher A Knight, Harrison C. Brown, Kinnede R. White, H. Trent Spencer, Christopher B Doering, Sunil S. Raikar
Journal: Blood
Blood (2023) 142 (Supplement 1): 4191.
https://doi.org/10.1182/blood-2023-190281
Published: 2023
Journal Articles

Utilizing Chemotherapy to Enhance the Anti-Tumor Properties of Ex Vivo Expanded Gamma Delta (γδ) T Cells Against Acute Myeloid Leukemia

Navdep Jhita, Kinnede R. White, Sunil S. Raikar
Journal: Blood
Blood (2023) 142 (Supplement 1): 6843.
https://doi.org/10.1182/blood-2023-190161
Published: 2023
Journal Articles

Project Evolve, Evaluation of Lineage Switch (LS), an International Initiative: Preliminary Results Reveal Dismal Outcomes in Patients with LS

Sara K. Silbert, Cynthia Harrison, D. Nathan Biery, Alexandra Semchenkova, Elena Zerkalenkova, Anna Alonso-Saladrigues, Kaylyn Utley, Ibrahim Aldoss, Liping Zhao, Sneha Fernandes, Jeremy D. Rubinstein, Naomi Torres Carapia, Bill H. Chang, Anant Vatsayan, Barbara De Moerloose, Holly L. Pacenta, Dennis John Kuo, Gabriele Escherich, Benjamin J. Lee, Michele S. Redell, Mandi R. Fitzjohn, Daniel P. Larson, Nicolas Duployez, Raymund S. Cuevo, Rui Rochelle He, David Dickens, Firas El Chaer, Kelly Reed, Matthias Wolfl, Sunil S. Raikar, Süreyya Savaşan, Latika Puri, Zhubin J. Gahvari, Aimee C. Talleur, Hisham Abdel-Azim, Aghiad Chamdin, Marlie R.M. Provost, Vanessa A. Fabrizio, Kerstin Mezger, Alexandra McLean Stevens, Emily M. Hsieh, Hao-Wei Wang, Constance M. Yuan, Ulrich A. Duffner, Jing Pan, Sara Ghorashian, Susana Rives, Chloe Hoang, Kara L. Davis, Elad Jacoby, Alexander Popov, Adam Lamble, Nirali N. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 4202.
https://doi.org/10.1182/blood-2023-182293
Published: 2023
Journal Articles

A Single Cell Atlas and Interactive Web-Resource of Pediatric Cancers and Healthy Bone Marrow

Hope L Mumme, Swati S Bhasin, Mariam Nawaz, Beena E Thomas, Chenbin Huang, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin
Journal: Blood
Blood (2022) 140 (Supplement 1): 2278–2279.
https://doi.org/10.1182/blood-2022-169153
Published: 2022
Journal Articles

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

Christopher Ronald Funk, Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar, Vikas A. Gupta, Shanmuganathan Chandrakasan, Jaquelyn T. Zoine, Andrew Fedanov, Sunil S. Raikar, Jean L. Koff, Christopher R. Flowers, Silvia Coma, Jonathan A. Pachter, Sruthi Ravindranathan, H. Trent Spencer, Mala Shanmugam, Edmund K. Waller
Journal: Blood
Blood (2022) 139 (4): 523–537.
https://doi.org/10.1182/blood.2021011597
Published: 2022
Includes: Supplemental data
Journal Articles

Standardization in the Diagnosis of Mixed Phenotype Acute Leukemia (MPAL): Semiquantitative, Universally Applicable Flow Cytometric Criteria for Immunophenotypic Lineage Assignment and Isolated MPO

Alexandra E. Kovach, Sunil S. Raikar, Matthew J. Oberley, Gerald Wertheim, Karen R Rabin, Jyotinder N. Punia, Alix E. Seif, Reuven J Schore, Dragos C. Luca, Terri Guinipero, William G Woods, Viviane Cahen, Maurice R.G. O'Gorman, Etan Orgel, Brent L. Wood
Journal: Blood
Blood (2021) 138 (Supplement 1): 4475.
https://doi.org/10.1182/blood-2021-154295
Published: 2021
Journal Articles

Single Cell RNA Sequencing Driven Characterization of Rare B/Myeloid and T/Myeloid Mixed Phenotype Acute Leukemia

Hope L Mumme, Swati S Bhasin, Beena E Thomas, Deborah DeRyckere, Sharon M. Castellino, Douglas K Graham, Sunil S. Raikar, Manoj Bhasin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3455.
https://doi.org/10.1182/blood-2021-153776
Published: 2021
Journal Articles

Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias

Hope L Mumme, Swati S Bhasin, Beena E Thomas, Bhakti Dwivedi, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3488.
https://doi.org/10.1182/blood-2021-154282
Published: 2021
Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-142513
Published: 2020
Journal Articles

Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia

Anthony Ross, MD, Miyoung Lee, PhD, Jamie Hamilton, Raira Ank, Priscilla Do, PhD, Jamie Story, Sunil S. Raikar, MD, Erik Dreaden, PhD, Christopher C. Porter, MD, Curtis J. Henry, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-136573
Published: 2020
Journal Articles

Clinical Outcomes in Pediatric Mixed Phenotype Acute Leukemia (MPAL) Differ Depending on Disease Classification Criteria; A Multi-Center Cohort Study

Matthew J. Oberley, MD PhD, Gerald Wertheim, MD, PhD, Sunil S. Raikar, MD, Jemily Malvar, Richard Sposto, PhD, Jyotinder N. Punia, MD, Karen R. Rabin, MD PhD, Alix E. Seif, MD, Reuven J. Schore, MD, Dragos C. Luca, MD, Terri Guinipero, MD, William G. Woods, MD, Maurice R.G. O'Gorman, MD PhD, Etan Orgel, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4080.
https://doi.org/10.1182/blood-2018-99-117377
Published: 2018
Journal Articles

Minimal Residual Disease Risk-Stratification in Pediatric Mixed Phenotype Acute Leukemia: Results of a Multi-Center Cohort Study

Matthew J. Oberley, MD PhD, Sunil S. Raikar, MD, Jemily Malvar, Gerald Wertheim, MD, PhD, Alix E. Seif, MD, Terri Guinipero, MD, Richard Sposto, PhD, Karen R. Rabin, MD PhD, Jyotinder N. Punia, MD, Reuven J. Schore, MD, Dragos C. Luca, MD, William G. Woods, MD, Maurice R.G. O'Gorman, MD PhD, Etan Orgel, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 558.
https://doi.org/10.1182/blood-2018-99-113606
Published: 2018
Journal Articles

Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival

Clinical Trials & Observations
Sunil S. Raikar, Sunita I. Park, Traci Leong, David L. Jaye, Frank G. Keller, John T. Horan, William G. Woods
Journal: Blood
Blood (2018) 131 (5): 573–577.
https://doi.org/10.1182/blood-2017-09-807602
Published: 2018
Includes: Supplemental data
Journal Articles

Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5

Sunil S Raikar, MD, Lauren C Fleischer, Robert Moot, B.S., Na Yoon Paik, B.S., Kristopher Knight, B.S., Christopher B Doering, PhD, H. Trent Spencer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4462.
https://doi.org/10.1182/blood.V130.Suppl_1.4462.4462
Published: 2017