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Journal Articles

Small Molecule Inhibitors of EYA2 Slow Proliferation of SIX1-Expressing Pediatric Leukemias

Waitman Aumann, Dongdong Chen, Lyndsey Alexander, Travis Reese, Lukas Gardner, Xiang Wang, Rui Zhou, Heide Ford, Daniel S. Wechsler

Blood (2024) 144 (Supplement 1): 5837.

https://doi.org/10.1182/blood-2024-209244

Published: 2024

Journal Articles

Genetic and Pharmacological Interruption of the SIX1/EYA2 Axis Impairs Leukemia Proliferation

Waitman Aumann, Catherine Lavau, Dongdong Chen, Travis Reese, Joan Kim, Heide Ford, Daniel S. Wechsler

Blood (2023) 142 (Supplement 1): 6069.

https://doi.org/10.1182/blood-2023-188014

Published: 2023

Journal Articles

A Single Cell Atlas and Interactive Web-Resource of Pediatric Cancers and Healthy Bone Marrow

Hope L Mumme, Swati S Bhasin, Mariam Nawaz, Beena E Thomas, Chenbin Huang, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin

Blood (2022) 140 (Supplement 1): 2278–2279.

https://doi.org/10.1182/blood-2022-169153

Published: 2022

Journal Articles

A SIX1/EYA2 Inhibitor Impairs CALM-AF10 and Jurkat Leukemia Cell Proliferation

Waitman Kurt Aumann, Catherine P. Lavau, Dongdong Julie Chen, Amanda E. Conway, Heide Ford, Daniel S. Wechsler

Blood (2021) 138 (Supplement 1): 4331.

https://doi.org/10.1182/blood-2021-154156

Published: 2021

Journal Articles

Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias

Hope L Mumme, Swati S Bhasin, Beena E Thomas, Bhakti Dwivedi, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin

Blood (2021) 138 (Supplement 1): 3488.

https://doi.org/10.1182/blood-2021-154282

Published: 2021

Journal Articles

Establishing the Role of EPS15, DVL2 and Cortactin in CALM-AF10 Leukemogenesis

Rafi Kazi, Waitman Kurt Aumann, Pritha Bagchi, Donald Tope, Daniel S. Wechsler

Blood (2021) 138 (Supplement 1): 3312.

https://doi.org/10.1182/blood-2021-152644

Published: 2021

Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142513

Published: 2020

Journal Articles

Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis

Rafi Kazi, MD, Waitman K. Aumann, MDMS, Pritha Bagchi, PhD, Daniel S. Wechsler, MD PhD

Blood (2020) 136 (Supplement 1): 14.

https://doi.org/10.1182/blood-2020-138816

Published: 2020

Journal Articles

The SIX1 homeobox Gene Is a Novel Therapeutic Target in CALM-AF10 Leukemogenesis

Waitman K. Aumann, MDMS, Catherine P. Lavau, DVM, PhD, Amanda Harrington, MD, Donald Tope, Amanda E. Conway, PhD, Hengbo Zhou, PhD, Heide Ford, PhD, Daniel S. Wechsler, MD PhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-140754

Published: 2020

Journal Articles

The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice

Waitman K. Aumann, MDMS, Sei-Gyung K. Sze, MD, Veerain Gupta, Katelyn Ripple, Sarah Port, Ralph Kehlenbach, PhD, Daniel S. Wechsler, MD PhD, Catherine P. Lavau, DVM, PhD

Blood (2019) 134 (Supplement_1): 1434.

https://doi.org/10.1182/blood-2019-130530

Published: 2019

Journal Articles

SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia

Waitman K. Aumann, MDMS, Catherine P. Lavau, DVM, PhD, Amanda Harrington, MD, Amanda E. Conway, PhD, Daniel S. Wechsler, MD PhD

Blood (2019) 134 (Supplement_1): 5035.

https://doi.org/10.1182/blood-2019-130178

Published: 2019

Journal Articles

A Role for the CRM1 Nuclear Export Receptor in HOXA Gene Deregulation and CALM-AF10 Leukemogenesis

Waitman K. Aumann, MD, Jessica L. Heath, MD, Sei-Gyung K. Sze, MD, Amanda E. Conway, PhD, Catherine P. Lavau, DVM, PhD, Daniel S. Wechsler, MD PhD

Blood (2017) 130 (Supplement 1): 369.

https://doi.org/10.1182/blood.V130.Suppl_1.369.369

Published: 2017

Journal Articles

The CRM1 Nuclear Export Receptor Activates HOXA Gene Expression in Leukemogenesis

Catherine P Lavau, DVM, PhD, Jessica L Heath, MD, William H Lee, Amanda E Conway, PhD, Daniel S Wechsler, MD PhD

Blood (2014) 124 (21): 2190.

https://doi.org/10.1182/blood.V124.21.2190.2190

Published: 2014

Journal Articles

A CALM-derived nuclear export signal is essential for CALM-AF10–mediated leukemogenesis

Amanda E. Conway, Paula B. Scotland, Catherine P. Lavau, Daniel S. Wechsler

Blood (2013) 121 (23): 4758–4768.

https://doi.org/10.1182/blood-2012-06-435792

Published: 2013

Includes: Supplemental data

Journal Articles

Iron Deprivation Impairs Proliferation of CALM-AF10 leukemia Cells in Vitro and in Vivo

Jessica L Heath, MD, Joshua Weiss, Paula B. Scotland, PhD, Catherine P. Lavau, DVM, PhD, Daniel S. Wechsler, MD, PhD

Blood (2012) 120 (21): 1386.

https://doi.org/10.1182/blood.V120.21.1386.1386

Published: 2012

Journal Articles

WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4

Qian Liu, Haoqian Chen, Teresa Ojode, Xiangxi Gao, Sandra Anaya-O'Brien, Nicholas A. Turner, Jean Ulrick, Rosamma DeCastro, Corin Kelly, Adela R. Cardones, Stuart H. Gold, Eugene I. Hwang, Daniel S. Wechsler, Harry L. Malech, Philip M. Murphy, David H. McDermott

Blood (2012) 120 (1): 181–189.

https://doi.org/10.1182/blood-2011-12-395608

Published: 2012

Includes: Supplemental data

Journal Articles

CALM Insufficiency Impairs Leukemia Cell Proliferation by Limiting Iron Uptake

Catherine P. Lavau, DVM, PhD, Jessica L Heath, MD, Paula B. Scotland, PhD, Daniel S. Wechsler, MD, PhD

Blood (2011) 118 (21): 1478.

https://doi.org/10.1182/blood.V118.21.1478.1478

Published: 2011

Journal Articles

Complete Responses in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Using the mTOR Inhibitor Sirolimus (rapamycin)

Davi d T. Teachey, MD, Robert J Greiner, MD, Dirk Schwabe, MD, Jack Bleesing, MD, PhD, Catherine Scott Manno, MD, Kathleen Sullivan, MD, PhD, Daniel S. Wechsler, MD, PhD, Stephan A. Grupp, MD, PhD

Blood (2008) 112 (11): 2569.

https://doi.org/10.1182/blood.V112.11.2569.2569

Published: 2008

Journal Articles

Perturbed Endocytosis as a Mechanism of CALM-Dependent Leukemogenesis: Identification of Specific CALM Domains Required for Internalization and Demonstration of Prolonged JAK2 Signaling in Response to GM-CSF.

Natasha L. Brooks, MS, David A. Erichsen, Daniel S. Wechsler, MD, PhD

Blood (2007) 110 (11): 1817.

https://doi.org/10.1182/blood.V110.11.1817.1817

Published: 2007

Journal Articles

Perturbed Endocytosis by Leukemogenic CALM -Containing Fusion Proteins Is Associated with Prolonged Growth Factor Signaling and Enhanced Cellular Proliferation.

Mwe Mwe Chao, MD, David A. Erichsen, BS, Megan L. Krajewski, BS, Stefan K. Bohlander, MD, Daniel S. Wechsler, MD, PhD

Blood (2005) 106 (11): 2476.

https://doi.org/10.1182/blood.V106.11.2476.2476

Published: 2005

NARROW

Small Molecule Inhibitors of EYA2 Slow Proliferation of SIX1-Expressing Pediatric Leukemias

Genetic and Pharmacological Interruption of the SIX1/EYA2 Axis Impairs Leukemia Proliferation

A Single Cell Atlas and Interactive Web-Resource of Pediatric Cancers and Healthy Bone Marrow

A SIX1/EYA2 Inhibitor Impairs CALM-AF10 and Jurkat Leukemia Cell Proliferation

Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias

Establishing the Role of EPS15, DVL2 and Cortactin in CALM-AF10 Leukemogenesis

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis

The SIX1 homeobox Gene Is a Novel Therapeutic Target in CALM-AF10 Leukemogenesis

The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice

SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia

A Role for the CRM1 Nuclear Export Receptor in HOXA Gene Deregulation and CALM-AF10 Leukemogenesis

The CRM1 Nuclear Export Receptor Activates HOXA Gene Expression in Leukemogenesis

A CALM-derived nuclear export signal is essential for CALM-AF10–mediated leukemogenesis

Iron Deprivation Impairs Proliferation of CALM-AF10 leukemia Cells in Vitro and in Vivo

WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4

CALM Insufficiency Impairs Leukemia Cell Proliferation by Limiting Iron Uptake

Complete Responses in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Using the mTOR Inhibitor Sirolimus (rapamycin)

Perturbed Endocytosis as a Mechanism of CALM-Dependent Leukemogenesis: Identification of Specific CALM Domains Required for Internalization and Demonstration of Prolonged JAK2 Signaling in Response to GM-CSF.

Perturbed Endocytosis by Leukemogenic CALM -Containing Fusion Proteins Is Associated with Prolonged Growth Factor Signaling and Enhanced Cellular Proliferation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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