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Christopher C. Porter
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Journal Articles

Single-Cell Profiling of the Immune Response Following Siglec 15 Knockout in Leukemia Cells

Marina E Michaud, Jodi Dougan, Dailia B. Francis, Mojtaba Bakhtiari, Christopher C. Porter, Manoj Bhasin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1365.
https://doi.org/10.1182/blood-2024-194233
Published: 2024
Journal Articles

Modulating the Vasoactive Intestinal Peptide (VIP) Pathway Reprograms Superior CAR T Cells

Heather K. Lin, Dejah Blake, Kory Wells, Ruby Freeman, Abhijay Mudigonda, William Liu, Alysa N Evans, Subir Goyal, Tongrui Liu, Christopher Ronald Funk, Tanisha Sinha, Elyse Christensen, Naeman Mahmood, Fan Fei, Brad Heller, Paul Chun, Tenzin Passang, Sruthi Ravindranathan, Jodi Dougan, Christopher C. Porter, Chrystal Paulos, Anupam Patgiri, Lily Yang, Edmund K. Waller, Sarwish Rafiq
Journal: Blood
Blood (2024) 144 (Supplement 1): 7154.
https://doi.org/10.1182/blood-2024-208090
Published: 2024
Journal Articles

The Immune Checkpoint Siglec-15 in Promoting Immune Dysregulation in Non-Hodgkin's Lymphomas

Dailia B. Francis, Jodi Dougan, Claire Pillsbury, Sunita Park, Solomon Langermann, Jean L. Koff, Ziyi Li, Christopher R. Flowers, Christopher C. Porter
Journal: Blood
Blood (2023) 142 (Supplement 1): 4367.
https://doi.org/10.1182/blood-2023-190405
Published: 2023
Journal Articles

A Single Cell Atlas and Interactive Web-Resource of Pediatric Cancers and Healthy Bone Marrow

Hope L Mumme, Swati S Bhasin, Mariam Nawaz, Beena E Thomas, Chenbin Huang, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin
Journal: Blood
Blood (2022) 140 (Supplement 1): 2278–2279.
https://doi.org/10.1182/blood-2022-169153
Published: 2022
Journal Articles

High-Efficiency Multi-Drug Functional Profiling in a Microfluidic Device Towards Personalized Predictions in Pediatric Leukemia

Evelyn Kendall Williams, Dan Y. Zhang, Ryan J Summers, Jamie Oakley, Melissa L. Kemp, Christopher C. Porter, Wilbur A. Lam
Journal: Blood
Blood (2022) 140 (Supplement 1): 7848–7849.
https://doi.org/10.1182/blood-2022-162384
Published: 2022
Journal Articles

Siglec-15 Is a Novel Immunomodulatory Protein and Therapeutic Target in Acute Lymphoblastic Leukemia

Claire E. Pillsbury, Jairo A. Fonseca, Jodi Dougan, Hasan Abukharma, Gloria Gonzalez-Flamenco, Sunita I. Park, Linda N. Liu, Christopher C. Porter
Journal: Blood
Blood (2021) 138 (Supplement 1): 515.
https://doi.org/10.1182/blood-2021-153647
Published: 2021
Journal Articles

Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias

Hope L Mumme, Swati S Bhasin, Beena E Thomas, Bhakti Dwivedi, Deborah DeRyckere, Sharon M. Castellino, Daniel S. Wechsler, Sunil S. Raikar, Christopher C. Porter, Douglas K Graham, Manoj Bhasin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3488.
https://doi.org/10.1182/blood-2021-154282
Published: 2021
Journal Articles

Microfluidic Multi-Drug and Multi-Dose Functional Profiling Towards Personalized Clinical Predictions in Pediatric Leukemia

Evelyn Kendall Williams, Dan Y. Zhang, Ryan J Summers, Jamie Oakley, Christopher C. Porter, Wilbur A. Lam
Journal: Blood
Blood (2021) 138 (Supplement 1): 2960.
https://doi.org/10.1182/blood-2021-152079
Published: 2021
Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-142513
Published: 2020
Journal Articles

Siglec-15 Is a Novel Immunomodulatory Protein and Therapeutic Target in Childhood Leukemia

Claire E. Pillsbury, Jairo A. Fonseca, MD, Jodi Dougan, Hasan Abukharma, Linda N. Liu, PhD, Christopher C. Porter, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-142833
Published: 2020
Journal Articles

Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia

Anthony Ross, MD, Miyoung Lee, PhD, Jamie Hamilton, Raira Ank, Priscilla Do, PhD, Jamie Story, Sunil S. Raikar, MD, Erik Dreaden, PhD, Christopher C. Porter, MD, Curtis J. Henry, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-136573
Published: 2020
Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2316.
https://doi.org/10.1182/blood-2019-132032
Published: 2019
Journal Articles

ETV6-related thrombocytopenia and leukemia predisposition

Jorge Di Paola, Christopher C. Porter
Journal: Blood
Blood (2019) 134 (8): 663–667.
https://doi.org/10.1182/blood.2019852418
Published: 2019
Includes: Supplemental data
Journal Articles

Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms

Lucy Godley, MD PhD, Xi Luo, PhD, Justyne Ross, Sarah Jackson, Anupriya Agarwal, PhD, Panagiotis Baliakas, MD PhD, Alison A. Bertuch, MD PhD, Anna L. Brown, PhD BSc, Michael C. Chicka, PhD, Courtney D. DiNardo, MD MSc, Mark D. Fleming, MD DPhil, Sioban Keel, MD, Chimene Kesserwan, MD, Zejuan Li, MD, Minjie Luo, PhD, Luca Malcovati, MD, Shannon K. McWeeney, PhD, Kim E. Nichols, MD, Christopher C. Porter, MD, Anna Raimbault, PhD, Lesley Rawlings, PhD, Mark Routbort, MD PhD, Gabriella Ryan, Jean Soulier, MD PhD, Nancy E. Speck, PhD, Tom Vulliamy, Michael Francis Walsh, MD, Ying Wang, Liying Zhang, Sharon Plon, MD PhD, David Wu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5849.
https://doi.org/10.1182/blood-2018-99-118979
Published: 2018
Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1035.
https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035
Published: 2017
Journal Articles

ETV6 Regulates Pax5 Expression in Early B Cell Development

Courtney L. Jones, PhD, Gregory Kirkpatrick, Courtney Fleenor, Welsh Seth, Leila J Noetzli, BS, Susan Fosmire, Dmitry Baturin, Xiayuan Liang, MD, Giovanny Hernandez, Eric Martin Pietras, PhD, Craig T Jordan, PhD, Jesse W Rowley, PhD, Jorge Di Paola, MD, James R. Hagman, Christopher C. Porter, MD
Journal: Blood
Blood (2016) 128 (22): 2655.
https://doi.org/10.1182/blood.V128.22.2655.2655
Published: 2016
Journal Articles

IFN-γ Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils

Michael A Ellison, PhD, Christy M Gearheart, PhD, Christopher C. Porter, MD, Daniel R. Ambruso, MD
Journal: Blood
Blood (2016) 128 (22): 1328.
https://doi.org/10.1182/blood.V128.22.1328.1328
Published: 2016
Journal Articles

A Dominant Negative Mutation (p.P214L) in ETV6 is Associated with Megakaryocyte and Erythroid Transcript Misregulation

Leila Noetzli, BS, Jesse W Rowley, PhD, Michael U Callaghan, MD, Madhvi Rajpurkar, MD, Alisa B. Lee-Sherick, MD, Christopher C. Porter, MD, Andrew S. Weyrich, PhD, Jorge A. Di Paola, MD
Journal: Blood
Blood (2015) 126 (23): 76.
https://doi.org/10.1182/blood.V126.23.76.76
Published: 2015
Journal Articles

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia

Courtney L. Jones, Christy M. Gearheart, Susan Fosmire, Cristina Delgado-Martin, Nikki A. Evensen, Karen Bride, Angela J. Waanders, Faye Pais, Jinhua Wang, Teena Bhatla, Danielle S. Bitterman, Simone R. de Rijk, Wallace Bourgeois, Smita Dandekar, Eugene Park, Tamara M. Burleson, Pillai Pallavi Madhusoodhan, David T. Teachey, Elizabeth A. Raetz, Michelle L. Hermiston, Markus Müschen, Mignon L. Loh, Stephen P. Hunger, Jinghui Zhang, Michael J. Garabedian, Christopher C. Porter, William L. Carroll
Journal: Blood
Blood (2015) 126 (19): 2202–2212.
https://doi.org/10.1182/blood-2015-04-639138
Published: 2015
Includes: Supplemental data
Journal Articles

Combined Inhibition of Wee1 and Poly(ADP Ribose) Polymerase1/2 Synergistically Inhibits Acute Myeloid Leukemia Cells By Enhancing DNA Damage and the Induction of Apoptosis

Jonathan C Snedeker, Tamara M Burleson, Raoul Tibes, MD PhD, Christopher C. Porter, MD
Journal: Blood
Blood (2014) 124 (21): 3621.
https://doi.org/10.1182/blood.V124.21.3621.3621
Published: 2014