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Ryan J Summers
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Journal Articles

Nelarabine Is Active in Pediatric T/Myeloid Mixed Phenotype Acute Leukemia

Ryan J Summers, Hope L Mumme, Anjali Khanna, Manoj Bhasin, Tamara P. Miller, Sunil S Raikar
Journal: Blood
Blood (2024) 144 (Supplement 1): 5902.
https://doi.org/10.1182/blood-2024-205142
Published: 2024
Journal Articles

SNPing away poor outcomes in T-ALL

Ryan J. Summers, David T. Teachey
Journal: Blood
Blood (2024) 144 (9): 924–925.
https://doi.org/10.1182/blood.2024024594
Published: 2024
Journal Articles

How I treat early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) in children

Ryan J Summers, David Trent Teachey, Stephen P Hunger
Journal: Blood
Blood blood.2023023155.
https://doi.org/10.1182/blood.2023023155
Published: 2024
Journal Articles

Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children’s Oncology Group study

Clinical Trials & Observations
Brent L. Wood, Meenakshi Devidas, Ryan J. Summers, Zhiguo Chen, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Naomi J. Winick, Michael J. Borowitz, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Kimberly P. Dunsmore, David T. Teachey, Stuart S. Winter
Journal: Blood
Blood (2023) 142 (24): 2069–2078.
https://doi.org/10.1182/blood.2023020678
Published: 2023
Includes: Supplemental data
Journal Articles

High-Efficiency Multi-Drug Functional Profiling in a Microfluidic Device Towards Personalized Predictions in Pediatric Leukemia

Evelyn Kendall Williams, Dan Y. Zhang, Ryan J Summers, Jamie Oakley, Melissa L. Kemp, Christopher C. Porter, Wilbur A. Lam
Journal: Blood
Blood (2022) 140 (Supplement 1): 7848–7849.
https://doi.org/10.1182/blood-2022-162384
Published: 2022
Journal Articles

Analysis of Single Cell Transcriptomics in Paired Pediatric T-ALL Samples Collected at Diagnosis and Following End of Induction Therapy Reveals an MRD-Associated Stem Cell Signature

Swati S Bhasin, Beena E Thomas, Ryan J Summers, Debasree Sarkar, Hope L Mumme, Mohammed Emam Mansour, William Pilcher, Sunita I. Park, Sharon M. Castellino, Deborah DeRyckere, Manoj Bhasin, Douglas K Graham
Journal: Blood
Blood (2021) 138 (Supplement 1): 1311.
https://doi.org/10.1182/blood-2021-153841
Published: 2021
Journal Articles

Microfluidic Multi-Drug and Multi-Dose Functional Profiling Towards Personalized Clinical Predictions in Pediatric Leukemia

Evelyn Kendall Williams, Dan Y. Zhang, Ryan J Summers, Jamie Oakley, Christopher C. Porter, Wilbur A. Lam
Journal: Blood
Blood (2021) 138 (Supplement 1): 2960.
https://doi.org/10.1182/blood-2021-152079
Published: 2021
Journal Articles

Therapeutic Targeting of Mertk and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia

Ryan J Summers, Juhi Jain, Eleana Vasileiadi, Brittany Smith, Madison Stout, James Kelvin, Xiaodong Wang, Stephen V Frye, H. Shelton Earp, Jeffrey W. Tyner, Erik Dreaden, Deborah DeRyckere, Douglas K Graham
Journal: Blood
Blood (2021) 138 (Supplement 1): 1184.
https://doi.org/10.1182/blood-2021-151726
Published: 2021
Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-142513
Published: 2020
Journal Articles

Characterization of T-ALL-Specific Heterogenous Blast Populations Using High Resolution Single Cell Profiling

Swati S Bhasin, PhD, Ryan J Summers, MD, Beena E Thomas, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Sharon M. Castellino, MD MSc, Manoj Bhasin, PhD, Douglas K Graham, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-143017
Published: 2020
Journal Articles

Mertk Is a Therapeutic Target in Early T-Precursor Acute Lymphoblastic Leukemia

Ryan J Summers, MD, Katherine A Minson, MD, Stephen V Frye, PhD, Xiaodong Wang, PhD, H. Shelton Earp, III, MD, Deborah DeRyckere, PhD, Douglas K. Graham, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2536.
https://doi.org/10.1182/blood.V130.Suppl_1.2536.2536
Published: 2017
Journal Articles

Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein

Ryan J. Summers, Shannon L. Meeks, John F. Healey, Harrison C. Brown, Ernest T. Parker, Christine L. Kempton, Christopher B. Doering, Pete Lollar
Journal: Blood
Blood (2011) 117 (11): 3190–3198.
https://doi.org/10.1182/blood-2010-09-307074
Published: 2011
Includes: Supplemental data
Journal Articles

N1922S Mutation In the Factor VIII A3 Domain Produces a Rate-Limiting, Domain-Specific Folding Defect Leading to Hyposecretion of a Functional Protein

Ryan J. Summers, B.S., Shannon L. Meeks, MD, John F. Healey, B.S., Harrison C. Brown, BBA, Ernest T Parker, BA, Christopher Doering, PhD, Christine L. Kempton, MD, MSc, John (Pete) S. Lollar, III, MD
Journal: Blood
Blood (2010) 116 (21): 2209.
https://doi.org/10.1182/blood.V116.21.2209.2209
Published: 2010