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Harrison C. Brown
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Journal Articles

Ancestral L-Asparaginases Are Cytotoxic Against ALL Cell Lines with Predicted Reduced Immunogenicity

Free
Kristopher Adrian Knight, Harrison C. Brown, Mathew S. Karpen, H. Trent Spencer, Christopher B. Doering, Sunil S Raikar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4169.
https://doi.org/10.1182/blood-2024-205342
Published: 2024
Journal Articles

Development of a Novel L-Asparaginase with Enhanced Properties Using Ancestral Sequence Reconstruction

Free
Kristopher A Knight, Harrison C. Brown, Kinnede R. White, H. Trent Spencer, Christopher B Doering, Sunil S. Raikar
Journal: Blood
Blood (2023) 142 (Supplement 1): 4191.
https://doi.org/10.1182/blood-2023-190281
Published: 2023
Journal Articles

Bioengineered Coagulation Factor VIII Enables Long-Term Correction Of Murine Hemophilia A Following Liver-Directed Adeno-Associated Viral Vector Delivery

Free
Harrison C. Brown, BBA, Jordan E Shields, Shangzhen Zhou, MD, J. Fraser Wright, PhD, H. Trent Spencer, PhD, Christopher B Doering, PhD
Journal: Blood
Blood (2013) 122 (21): 4210.
https://doi.org/10.1182/blood.V122.21.4210.4210
Published: 2013
Journal Articles

BCL11A Polymorphism and HbF Response to Hydroxyurea in Adult Patients with Sickle Cell Disease

Free
Philip Sobash, Ferdane Kutlar, MD, Harrison C. Brown, BBA, Betsy Clair, Abdullah Kutlar, MD
Journal: Blood
Blood (2011) 118 (21): 1051.
https://doi.org/10.1182/blood.V118.21.1051.1051
Published: 2011
Journal Articles

Exploratory Study of Haptoglobin Levels by Genotype in Adult Sickle Cell Patients

Free
Harrison C. Brown, BBA, Ferdane Kutlar, MD, Betsy Clair, Abdullah Kutlar, MD
Journal: Blood
Blood (2011) 118 (21): 2145.
https://doi.org/10.1182/blood.V118.21.2145.2145
Published: 2011
Journal Articles

Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein

Free
Ryan J. Summers, Shannon L. Meeks, John F. Healey, Harrison C. Brown, Ernest T. Parker, Christine L. Kempton, Christopher B. Doering, Pete Lollar
Journal: Blood
Blood (2011) 117 (11): 3190–3198.
https://doi.org/10.1182/blood-2010-09-307074
Published: 2011
Includes: Supplemental data
Journal Articles

Differential Engagement of the Unfolded Protein Response by Human and Porcine Factor VIII

Free
Harrison C. Brown, BBA, Bagirath Gangadharan, MS, Christopher Doering, PhD
Journal: Blood
Blood (2010) 116 (21): 2224.
https://doi.org/10.1182/blood.V116.21.2224.2224
Published: 2010
Journal Articles

N1922S Mutation In the Factor VIII A3 Domain Produces a Rate-Limiting, Domain-Specific Folding Defect Leading to Hyposecretion of a Functional Protein

Free
Ryan J. Summers, B.S., Shannon L. Meeks, MD, John F. Healey, B.S., Harrison C. Brown, BBA, Ernest T Parker, BA, Christopher Doering, PhD, Christine L. Kempton, MD, MSc, John (Pete) S. Lollar, III, MD
Journal: Blood
Blood (2010) 116 (21): 2209.
https://doi.org/10.1182/blood.V116.21.2209.2209
Published: 2010