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Nicolas Boissel
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Journal Articles

Handling of Allograft As an Intercurrent Event in Randomized Controlled Trials in Acute Leukemias: A Systematic Review

Roxane Couturier, Loic Vasseur, Nicolas Boissel, Hervé Dombret, Sylvie Chevret, Jérôme Lambert
Journal: Blood
Blood (2024) 144 (Supplement 1): 7449.
https://doi.org/10.1182/blood-2024-194149
Published: 2024
Journal Articles

Determinants of Isolated CNS Relapse in Adults with Philadelphia-Negative Acute Lymphoblastic Leukemia. from Graall-2005 to -2014 Trials

Nicolas Boissel, Emilie Lemasle, Sylvain Chantepie, Thibaut Leguay, Corentin Orvain, Françoise Huguet, Yosr Hicheri, Nathalie Dhédin, Patrice Chevallier, Marie Balsat, Sébastien Maury, Hunault-Berger Mathilde, Karin Bilger, Eolia Brissot, Sebastian Wittnebel, Julie Guerder, Sarah Bonnet, Pascal Turlure, Anne Huynh, Claire Bories, Michael Gregor, Natacha Mauz, Ahmad Aljijakli, Carlos Graux, Yves Chalandon, Norbert Ifrah, Vahid Asnafi, Emmanuelle Clappier, Véronique Lheritier, Hervé Dombret
Journal: Blood
Blood (2024) 144 (Supplement 1): 731.
https://doi.org/10.1182/blood-2024-198614
Published: 2024
Journal Articles

WU-CART-007 (WT-7), an Allogeneic CAR T-Cell Targeting CD7 in Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL): Phase 2 Results

Armin Ghobadi, Ibrahim Aldoss, Shannon L. Maude, Deepa Bhojwani, Rawan Faramand, Ashish Bajel, Friso G. J. Calkoen, Alan S. Wayne, Bhagirathbhai Dholaria, Ryan J Mattison, Anita W. Rijneveld, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Michael P. Rettig, Maria del Rosario, Stephen Moran, Alexander Hamil, Ouiam Bakkacha, Deborah Masters, Justo L. Gonzalez, Michael Munroe, Laura Simpson, Preeta Dasgupta, Tony Wu, John Muth, Haley Irons, Brett Ramsey, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 3450.
https://doi.org/10.1182/blood-2024-202005
Published: 2024
Journal Articles

WUC007-03: A Phase 2 Study of Anti-CD7 Allogenic CAR-T Cells (WT-7) in Patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL)

Armin Ghobadi, Shannon L. Maude, Ibrahim Aldoss, Ashish Bajel, Ryan J Mattison, Deepa Bhojwani, Alan S. Wayne, Rawan Faramand, Bhagirathbhai Dholaria, Seong Lin Khaw, Anita W. Rijneveld, Friso G. J. Calkoen, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Andrej Lissat, Stefan Schwartz, Peter Bader, Fabian Lang, Michael P. Rettig, Haley Irons, Brett Ramsey, John Muth, Laura Simpson, Preeta Dasgupta, Stephen Moran, Michael Munroe, Maria del Rosario, Tony Wu, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Alexander Hamil, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 7225.
https://doi.org/10.1182/blood-2024-201825
Published: 2024
Journal Articles

Resolve AML 001: An Adaptive Open-Label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of Cctx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients with r/r AML

Marion Subklewe, Nicolas Boissel, Stephan Mielke, Pere Barba, Elisa Sala, Eric Deconinck, Olivia Fiere, Jonathan Jaeger, Chloe Vasseghi, Marina Deschamps, Christophe Ferrand, Edouard De Dreuzy, Richard Sainson, Jens Hasskarl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2883.2.
https://doi.org/10.1182/blood-2024-203204
Published: 2024
Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

How to Administer Pegaspargase during Induction Treatment of Acute Lymphoblastic Leukemia in Children and Adolescents? Results of the Caall-F01, a Multicentre Randomized Clinical Trial from the French Pediatric Cancer Society (SFCE)

Marion Strullu, Arnaud Petit, Carine Halfon-Domenech, Anne-France Ray-Lunven, Paul Saultier, Wadih Abou Chahla, Stéphane Ducassou, Marlène Pasquet, Caroline Thomas, Cécile Pochon, Virginie Gandemer, Catherine Paillard, Alexandre Theron, Claire Pluchart, Pascale Schneider, Damien Bodet, Isabelle Pellier, Pierre Simon Rohrlich, Anne-France Jourdain, Pauline Simon, Frederic Millot, Liana Carausu, Corinne Armari Alla, Camille Leglise, Justyna Kanold, Claire Desplantes, Sandrine Thouvenin, Christophe Piguet, Nicolas Boissel, Wendy Cuccuini, Vahid Asnafi, Aurélie Caye-Eude, Hélène Cavé, Guy Leverger, Jean-François Benoist, Yves Bertrand, Sylvie Chevret, André Baruchel
Journal: Blood
Blood (2024) 144 (Supplement 1): 2814.
https://doi.org/10.1182/blood-2024-205327
Published: 2024
Journal Articles

Switch of Asparaginase Formulation Based on Antibody Monitoring in Adults with Philadelphia-Negative Adult Lymphoblastic Leukemia. Results of the Graall-2014 Trial

Marie Balsat, Corentin Orvain, Jean-François Benoist, Nicolas De Roux, Thibaut Leguay, Françoise Huguet, Patrice Chevallier, Cendrine Josson, Christine Bain-Wendlinger, Yosr Hicheri, Anne Thiebaut, Martine Escoffre-Barbe, Thomas Cluzeau, Florence Pasquier, Ana Berceanu, Florence Van Obbergh, Jamilé Frayfer, Gaëlle Guillerm, Victoria Cacheux, Isabelle Plantier, Laurence Sanhes, Chantal Himberlin, Jacques Vargaftig, Sabine Tricot, Yves Chalandon, Carlos Graux, Véronique Lheritier, Hervé Dombret, Hunault-Berger Mathilde, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1434.
https://doi.org/10.1182/blood-2024-199110
Published: 2024
Journal Articles

Characteristics and Outcome Determinants in Children, Adolescents and Young Adults Who Failed Tisagenlecleucel for B-Cell Acute Lymphoblastic Leukemia

Nicolas Lecornec, Florence Rabian, Marie-Emilie Dourthe, Florian Chevillon, Karima Yakouben, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Rathana Kim, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, André Baruchel, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1433.
https://doi.org/10.1182/blood-2024-209895
Published: 2024
Journal Articles

MP0533 (CD33 x CD123 x CD70 x CD3), a Tetra-Specific CD3-Engaging Darpin for the Treatment of Patients with Relapsed/Refractory AML or MDS/AML: Results of an Ongoing Phase 1/2a Study

Mojca Jongen-Lavrencic, Thomas Pabst, Pierre Bories, Laimonas Griškevičius, Gerwin Huls, David C. de Leeuw, Steffen Boettcher, Arnaud Pigneux, Nicolas Boissel, Mariola Dymkowska, Christiane Andrieu, Oliver Schönborn-Kellenberger, Paul G. Baverel, Zita Arany, Elena Fernandez, Ana-Maria Florescu, Michael P. Sanderson, Anne Goubier, Vladimir Kirkin, Philippe Legenne, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 2881.
https://doi.org/10.1182/blood-2024-199211
Published: 2024
Journal Articles

IL-1RAP Is a Targetable Surface Antigen in Relapsed/Refractoy AML

Mohamad Sabbah, Morgane Fontaine, Kim Pacchiardi, Alexis Delabrière, Stephane De Botton, Catherine Lonchamp, Renaud Buffet, Laure Farnault, Jean-Baptiste Micol, Typhaine Dumas-Rivero, Emmanuel Raffoux, Lionel Ades, Nicolas Boissel, Juliette Lambert, Kevin-James Wattebled, Matthieu Duchmann, Karine Celli-Lebras, Alexandra Coelho, Hervé Dombret, Edouard De Dreuzy, Marina Deschamps, Christophe Ferrand, Jens Hasskarl, Richard Sainson, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 4311.
https://doi.org/10.1182/blood-2024-199673
Published: 2024
Journal Articles

NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients

Clinical Trials & Observations
Mathieu Simonin, Loïc Vasseur, Etienne Lengliné, Ludovic Lhermitte, Aurélie Cabannes-Hamy, Marie Balsat, Aline Schmidt, Marie-Emilie Dourthe, Aurore Touzart, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Françoise Huguet, Stéphane Ducassou, Véronique Lhéritier, Yves Chalandon, Norbert Ifrah, Hervé Dombret, Elizabeth Macintyre, Arnaud Petit, Philippe Rousselot, Jérôme Lambert, André Baruchel, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (15): 1570–1580.
https://doi.org/10.1182/blood.2023023754
Published: 2024
Includes: Supplemental data
Journal Articles

Cerebrospinal fluid distribution and pharmacokinetics of ponatinib in Ph1 + acute lymphoblastic leukemia

Pierre Walczak, Sofiane Fodil, Nicolas Vignal, Aurélie Cabannes-Hamy, Nicolas Boissel, Emmanuel Raffoux, Jean-Michel Cayuela, Lauriane Goldwirt, Etienne Lengliné
Journal: Blood
Blood (2024) 144 (10): 1127–1130.
https://doi.org/10.1182/blood.2024024838
Published: 2024
Journal Articles

Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL

Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe, Patrick Villarese, Stéphane Ducassou, Isabelle Arnoux, Jean-Michel Cayuela, Marie Balsat, Lucien Courtois, Guillaume Andrieu, Aurore Touzart, Françoise Huguet, Arnaud Petit, Norbert Ifrah, Hervé Dombret, André Baruchel, Elizabeth Macintyre, Claude Preudhomme, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (9): 988–1000.
https://doi.org/10.1182/blood.2023022154
Published: 2024
Includes: Supplemental data
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Diagnosis, prognostic factors, and assessment of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1891–1902.
https://doi.org/10.1182/blood.2023020794
Published: 2024
Includes: Supplemental data
Journal Articles

Management of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1903–1930.
https://doi.org/10.1182/blood.2023023568
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Frontline Consolidation with Nelarabine for Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia. Results of the Graall-2014/T Atriall Phase 2 Study

Nicolas Boissel, Carlos Graux, Francoise Huguet, Florence Pasquier, Aurore Touzart, Thomas Cluzeau, Ludovic Lhermitte, Eric Delabesse, Patrice Chevallier, Mathilde Hunault, Cedric Pastoret, Sebastien Maury, Nathalie Grardel, Martine Escoffre Barbe, Pascal Turlure, Beat Schafer, Marie Balsat, Philippe Rousselot, Thibaut Leguay, Eric Jourdan, Delphine Pranger, Michael Gregor, Emilie Lemasle, Anne Marie Ronchetti, Ana Berceanu, Ingrid Lafon, Madalina Uzunov, Etienne Lengline, Norbert Ifrah, Yves Chalandon, Véronique Lhéritier, Vahid Asnafi, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 962.
https://doi.org/10.1182/blood-2023-177696
Published: 2023
Journal Articles

Low Disease Burden Pre-CAR-T Cell Therapy for Children and AYA with B-ALL Is Associated with an Impaired Outcome When Obtained through Intensification of the Bridging Therapy

Nicolas Lecornec, Marie-Emilie Dourthe, Florence Rabian, Karima Yakouben, Florian Chevillon, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, Nicolas Boissel, André Baruchel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2134.
https://doi.org/10.1182/blood-2023-175045
Published: 2023