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Journal Articles

Multicenter phase 2 study of subcutaneous isatuximab plus bortezomib , lenalidomide and dexamethasone (Isa Sc-VRd) in transplant ineligible newly diagnosed multiple myeloma: Final analysis of the isasocut study (IFM 2022-05)

Free
Arthur Bobin, Rick Zhang, Mony Morisse, Anais Schavgoulidze, Stéphanie Ragot, Christophe Roul, Thomas Chalopin, Lydia Montes, Mamoun Dib, Mourad Tiab, Frederique Orsini Piocelle, Thorsten Braun, Julie Gay, Carla Araujo, Reza Tabrizi, Laure Vincent, Alberto Santagostino, karine Garnier, Douaa Dhahri, Mohamad Mohty, Magaret Macro, Murielle Roussel, Lionel Karlin, Philippe Moreau, Cyrille Touzeau, Aurore Perrot, Thierry Facon, Cyrille Hulin, Jill Corre, Salomon Manier, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 2275.
https://doi.org/10.1182/blood-2025-2275
Published: 2025
Journal Articles

Clinical and biological correlates of blast-transformed chronic myelomonocytic leukemia (CMML): A multicenter study of 493 paired cases at chronic phase and at blast transformation

Free
Clifford Csizmar, Guillermo Montalban-Bravo, Leila Cysique-Foinlan, Anuya Natu, Terra Lasho, Christy Finke, Aref Al-Kali, Hassan Alkhateeb, Ali Alsugair, Kebede Begna, Saubia Fathima, Naseema Gangat, Abhishek Mangaonkar, Antoine Saliba, Ayalew Tefferi, Margot Morabito, Nathalie Droin, Cyril Quivoron, Benjamin Podvin, Nicolas Duployez, Olivier Kosmider, Christophe Marzac, Sylvain Thépot, Mathieu Meunier, Céline Berthon, Thorsten Braun, Christophe Willekens, Stephane De Botton, Lionel Ades, Alexandre Bazinet, Kelly Chien, Danielle Hammond, Courtney DiNardo, Tapan Kadia, Rashmi Kanagal-Shamanna, Sanam Loghavi, Naveen Pemmaraju, Farhad Ravandi, Koji Sasaki, Hagop Kantarjian, Pierre Fenaux, Eric Solary, Guillermo Garcia-Manero, Aline Renneville, Mrinal Patnaik
Journal: Blood
Blood (2025) 146 (Supplement 1): 2081.
https://doi.org/10.1182/blood-2025-2081
Published: 2025
Journal Articles

Real-world patterns of treatment intensity and prognostic model performance in older AML: Insights from the french ALFA-PPP cohort

Free
Lin-Pierre Zhao, Céline Berthon, Lauren Fenwarth, Stephane De Botton, Thomas Cluzeau, Laure Farnault, Sylvain Chantepie, Pierre Arnautou, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Ahmad Aljijakli, Isabelle Plantier, Ollivier Legrand, Juliette Lambert, Christophe Willekens, Emmanuel Raffoux, Claire Bories, Emilie Lemasle, Kevin-James Wattebled, Ambroise Marçais, Celia Salanoubat, Pascal Turlure, Jamilé Frayfer, Benjamin Carpentier, Madalina Uzunov, Reda Garidi, Ioana Vaida, Renaud Buffet, Alexandra COELHO, Karine Celli-Lebras, Raphael Itzykson, Claude Preudhomme, Nicolas Duployez, Hervé Dombret, Lionel Ades
Journal: Blood
Blood (2025) 146 (Supplement 1): 454.
https://doi.org/10.1182/blood-2025-454
Published: 2025
Journal Articles

Real life treatments and outcomes of older patients aged more than 60 years with FLT3-mutated acute myeloid leukemia: Report from the multicentric french observational ALFA-PPP study

Free
Ramy Rahmé, Emmanuel Raffoux, Lionel Ades, Stephane De Botton, Nicolas Duployez, Alexandra COELHO, Jean-Baptiste Micol, Sylvain Chantepie, Thomas Cluzeau, Delphine Lebon, Pierre Arnautou, Mathieu Leclerc, Laure Farnault, Ollivier Legrand, Ahmad Aljijakli, Céline Berthon, Juliette Lambert, Claire Bories, Ambroise Marçais, Julia HIEULLE, Celia Salanoubat, Pascal Turlure, Kevin-James Wattebled, Benjamin Carpentier, Jamile Frayfer, Ioana Vaida, Madalina Uzunov, Reda Garidi, Luca Inchiappa, Karine Celli-Lebras, Dominique Penther, Raynier Devillier, Raphael Itzykson, Claude Preudhomme, Renaud Buffet, Herve Dombret, Thorsten Braun
Journal: Blood
Blood (2025) 146 (Supplement 1): 449.
https://doi.org/10.1182/blood-2025-449
Published: 2025
Journal Articles

Secondary-type acute myeloid leukemia is associated with a higher risk of invasive fungal infection during intensive induction therapy. a correlative study on the ALFA 0702 trial.

Free
Jean-Eudes Fahrner, Mauricette Michallet, Laurene Fenwarth, Mohamad Sobh, Stéphane Morisset, Alexandre Deloire, Emmanuel Raffoux, Stephane De Botton, Sylvain Chantepie, Stephane Girault, Céline Berthon, Sarah Bertoli, Stephane Lepretre, Pierre Yves Dumas, Juliette Lambert, Delphine Lebon, Cecile Pautas, Jean Valère Malfuson, Norbert Vey, Thorsten Braun, Felipe Suarez, Aline Schmidt, Remy Gressin, Caroline Bonmati, Karine Celli-Lebras, Mael Heiblig, Mohamed El-Hamri, Claude Preudhomme, Hervé Dombret, Anne Bergeron, Nicolas Duployez, Raphael Itzykson
Journal: Blood
Blood (2025) 146 (Supplement 1): 994.
https://doi.org/10.1182/blood-2025-994
Published: 2025
Journal Articles

Therapy-related core binding factor Acute Myeloid Leukemia – a Study of the french acute leukemia intergroup

Free
Mathilde Chanut, Loïc Vasseur, Matthieu Duchmann, Pierre Hirsch, Céline Berthon, Mael Heiblig, Thorsten Braun, Mathieu Leclerc, Jean Valère Malfuson, Delphine Lebon, Madalina Uzunov, Jean-Noel Bastie, Gian Matteo Pica, Marie-Anne Hospital, Thomas Cluzeau, Juliette Lambert, Lauris Gastaud, Karine Celli-Lebras, Arnaud Pigneux, Stephane De Botton, Christian Recher, Claude Preudhomme, Eric Jourdan, Herve Dombret, Nicolas Boissel, Nicolas Duployez, Raphael Itzykson, Jean-Baptiste Micol
Journal: Blood
Blood (2025) 146 (Supplement 1): 37.
https://doi.org/10.1182/blood-2025-37
Published: 2025
Journal Articles

Prognosis of the IGLV3-21 R110 Mutation in a Real-Life Chronic Lymphocytic Leukemia Cohort

Free
Merieme Bensalah, Amal Messaoudi, Carole Fleury, Giulia Tueur, Rémi Letestu, Marine Armand, Sabine Brechignac, Sarah Ivanoff, Valérie Vidal, Ramy Rahmé, Chadi Al Nawakil, Thorsten Braun, Catherine Thieblemont, Cymbalista Florence, Vincent Levy, Fanny Baran-Marszak, Grégory Lazarian
Journal: Blood
Blood (2024) 144 (Supplement 1): 3241.
https://doi.org/10.1182/blood-2024-200665
Published: 2024
Journal Articles

Reducing Infection Risks of Anti-BCMA Bispecific Antibodies in Multiple Myeloma: In-Hospital Vs. Hospital-at-Home Treatment

Free
Romain Winer, Marguerite Vignon, Mathis Collier, Guillemette Fouquet, Olivier Hermine, Clarisse Cazelles, Laurent Frenzel, Sylvain Choquet, Laurent Garderet, Karim Belhadj Merzoug, Thorsten Braun, Didier Bouscary, Marie-Laure Brandely-Piat, Clement Leclaire, Maya Gutierrez, Frederique Moufle, Cecile Chauvin, Arnaud Soulignac, Arsene Zogo, Philippe Moreau, Jeremie Zerbit
Journal: Blood
Blood (2024) 144 (Supplement 1): 2286.
https://doi.org/10.1182/blood-2024-204695
Published: 2024
Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Free
Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Free
Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Treatment of Adverse-Risk and Refractory/Relapsed Acute Myeloid Leukemia (AML) Patients with FLAG-IDA ± Venetoclax and CLAG-M: A Monocentric Experience

Free
Ramy Rahmé, Valérie Vidal, Thomas Hueso, Lucie Le Meur, Marthe Rigal, Sarah Ivanoff, Sabine Brechignac, Regis Peffault De Latour, Claude Gardin, Thorsten Braun
Journal: Blood
Blood (2023) 142 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2023-174356
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Free
Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

Gemtuzumab Ozogamicin for Patients with Newly Diagnosed CD33 Positive Acute Myeloid Leukemia: Results from a French Retrospective Observational Study

Free
Juliette Lambert, Emmanuel Raffoux, Delphine Lebon, Thorsten Braun, Mael Heiblig, Alberto Santagostino, Karin Gogat-Marchant, Cécile Pautas
Journal: Blood
Blood (2023) 142 (Supplement 1): 2893.
https://doi.org/10.1182/blood-2023-179575
Published: 2023
Journal Articles

CPX-351 in Patients with Newly Diagnosed Post Myeloproliferative Neoplasms Acute Myeloid Leukemia

Free
Sylvain Garciaz, Amine Belhabri, Romain Guieze, Laure Goursaud, Pierre Peterlin, Marie-Pierre Ledoux, Hunault-Berger Mathilde, Safia Chebrek, Jean-Baptiste Robin, Arnaud Pigneux, Sarah Bonnet, Caroline Bonmati, Sarah Bertoli, Thorsten Braun, Sylvain Chantepie, Mathieu Meunier, Mael Heiblig, Thomas Cluzeau, Eric Jourdan, Alban Villate, Christian Recher, Norbert Vey, Jerome Rey
Journal: Blood
Blood (2023) 142 (Supplement 1): 2917.
https://doi.org/10.1182/blood-2023-184591
Published: 2023
Journal Articles

Involvement of the JAK-STAT Pathway in the Molecular Landscape of Fusion-Free Myeloid Neoplasms with Eosinophilia

Free
Matthieu Groh, Laurène Fenwarth, Augustin Boudry, Elise Fournier, Alice Marceau-Renaut, Julie Abraham, Marly Barry, Philippe Blanche, Quentin Bodard, Thorsten Braun, Safia Chebrek, Rafael Daltro De Oliveira, Matthieu Decamp, Cécile Audrey Durel, Edouard Forcade, Mathieu Gerfaud-Valentin, Camille Golfier, Clement Gourguechon, Nathalie Grardel, Olivier Kosmider, Mathilde Labro, Sarah Melboucy Belkhir, Fatiha Merabet, Adrien Michon, Nihal Martis, Cécile Morice, Stephane Moreau, Antoine Néel, Franck E. Nicolini, Laurent Pascal, Florence Pasquier, Andrea Pieragostini, Catherine Roche-Lestienne, Philippe Rousselot, Anne Thiebaut, Jean-Francois Viallard, Mathieu Wemeau, Claude Preudhomme, Jean-Emmanuel Kahn, Guillaume Lefèvre, Nicolas Duployez
Journal: Blood
Blood (2023) 142 (Supplement 1): 78.
https://doi.org/10.1182/blood-2023-181250
Published: 2023
Journal Articles

Ixazomib, Pomalidomide and Dexamethasone (IxPd) in Relapsed or Refractory Multiple Myeloma (RRMM) Characterized with High-Risk Cytogenetics. IFM 2014-01

Free
Arthur Bobin, Salomon Manier, Joe De Keizer, Cyrille Hulin, Lionel Karlin, Denis Caillot, Clara Mariette, Carla Araujo, Bertrand Arnulf, Benoit Bareau, Karim Belhadj Merzoug, Lotfi Benboubker, Thorsten Braun, Claire Calmettes, Olivier Decaux, Mamoun Dib, Helene Demarquette, Pierre Feugier, Cécile Sonntag, Arnaud Jaccard, Pascal Lenain, Margaret Macro, Valentine Richez, Mourad Tiab, Laure Vincent, Hacene Zerazhi, Marie-Odile Petillon, Cyrille Touzeau, Aurore Perrot, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6724.
https://doi.org/10.1182/blood-2023-186599
Published: 2023
Journal Articles

Multicenter Open Label Phase 2 Study of Quadruplet-Based Regimen Iskpd (isatuximab plus pomalidomide and dexamethasone with carfilzomib) in Early Relapsed or Refractory Multiple Myeloma - IFM2018-03

Free
Arthur Bobin, Jerome Lambert, Stéfanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Lotfi Benboubker, Thomas Chalopin, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faiza Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini Piocelle, Laure Vincent, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6742.
https://doi.org/10.1182/blood-2023-185792
Published: 2023
Journal Articles

An unexpected partnership targeting FLT3wt AML

Free
Thorsten Braun
Journal: Blood
Blood (2022) 140 (24): 2529–2530.
https://doi.org/10.1182/blood.2022017344
Published: 2022
Journal Articles

Olutasidenib (FT-2102) Induces Durable Complete Remissions in Patients with Relapsed/Refractory mIDH1 Acute Myeloid Leukemia. Results from a Planned Interim Analysis of a Phase 2 Pivotal Clinical Trial

Free
Jorge E. Cortes, Pierre Fenaux, Karen Yee, Christian Recher, Andrew H. Wei, Pau Montesinos, David C Taussig, Arnaud Pigneux, Thorsten Braun, Antonio Curti, Carolyn Grove, Brian A. Jonas, Asim Khwaja, Pierre Peterlin, Olga Polyanskaya, Jennifer Sweeney, Julie Brevard, Emma Barrett, Stephane De Botton
Journal: Blood
Blood (2022) 140 (Supplement 1): 6193–6196.
https://doi.org/10.1182/blood-2022-167330
Published: 2022
Journal Articles

Prognostic Impact of Monoallelic Versus Biallelic TP53 Alterations in Intensively-Treated Adults AML Patients: A Retrospective Study from the ALFA Group

Free
Laurène Fenwarth, Loïc Vasseur, Nicolas Duployez, Claude Gardin, Christine Terré, Juliette Lambert, Stéphane de Botton, Karine Celli-Lebras, Pascal Turlure, Thomas Cluzeau, Thorsten Braun, Xavier Thomas, Christian Recher, Sylvain Chantepie, Cécile Pautas, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2022) 140 (Supplement 1): 737–738.
https://doi.org/10.1182/blood-2022-163044
Published: 2022