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Journal Articles

The IFM2017-03 Phase 3 Trial: A Dexamethasone Sparing-Regimen with Daratumumab and Lenalidomide for Frail Patients with Newly-Diagnosed Multiple Myeloma

Salomon Manier, Jérome Lambert, Cyrille Hulin, Kamel Laribi, Carla Araujo, Gian Matteo Pica, Cyrille Touzeau, Pascal Godmer, Bohrane Slama, Lionel Karlin, Frederique Orsini Piocelle, Mamoun Dib, Magaret Macro, Laurence Sanhes, Lydia Montes, Abderrazak El Yamani, Mourad Tiab, Reza Tabrizi, Laurent Garderet, Bruno Royer, Benoit Bareau, Aurore Perrot, Jean Yves Mary, Jill Corre, Herve Avet Loiseau, Philippe Moreau, Xavier Leleu, Thierry Facon
Journal: Blood
Blood (2024) 144 (Supplement 1): 774.
https://doi.org/10.1182/blood-2024-203045
Published: 2024
Journal Articles

Ixazomib, Pomalidomide and Dexamethasone (IxPd) in Relapsed or Refractory Multiple Myeloma (RRMM) Characterized with High-Risk Cytogenetics. IFM 2014-01

Arthur Bobin, Salomon Manier, Joe De Keizer, Cyrille Hulin, Lionel Karlin, Denis Caillot, Clara Mariette, Carla Araujo, Bertrand Arnulf, Benoit Bareau, Karim Belhadj Merzoug, Lotfi Benboubker, Thorsten Braun, Claire Calmettes, Olivier Decaux, Mamoun Dib, Helene Demarquette, Pierre Feugier, Cécile Sonntag, Arnaud Jaccard, Pascal Lenain, Margaret Macro, Valentine Richez, Mourad Tiab, Laure Vincent, Hacene Zerazhi, Marie-Odile Petillon, Cyrille Touzeau, Aurore Perrot, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6724.
https://doi.org/10.1182/blood-2023-186599
Published: 2023
Journal Articles

Multicenter Open Label Phase 2 Study of Quadruplet-Based Regimen Iskpd (isatuximab plus pomalidomide and dexamethasone with carfilzomib) in Early Relapsed or Refractory Multiple Myeloma - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéfanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Lotfi Benboubker, Thomas Chalopin, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faiza Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini Piocelle, Laure Vincent, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6742.
https://doi.org/10.1182/blood-2023-185792
Published: 2023
Journal Articles

Multicenter Open Label Phase 2 Study of Isatuximab Plus Pomalidomide and Dexamethasone with Carfilzomib in Relapsed or Refractory Multiple Myeloma. Iskpd - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéphanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Cyrille Hulin, Lotfi Benboubker, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faida Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4452–4453.
https://doi.org/10.1182/blood-2022-166870
Published: 2022
Journal Articles

A Dexamethasone Sparing-Regimen with Daratumumab and Lenalidomide in Frail Patients with Newly-Diagnosed Multiple Myeloma: Efficacy and Safety Analysis of the Phase 3 IFM2017-03 Trial

Salomon Manier, Jill Corre, Cyrille Hulin, Kamel Laribi, Carla Araujo, Gian-Matteo Pica, Cyrille Touzeau, Pascal Godmer, Bohrane Slama, Lionel Karlin, Frederique Orsini-Piocelle, Mamoun Dib, Margaret Macro, Laurence Sanhes, Aurore Perrot, Jean Yves Mary, Jerome Lambert, Herve Avet-Loiseau, Philippe Moreau, Xavier Leleu, Thierry Facon
Journal: Blood
Blood (2022) 140 (Supplement 1): 1369–1370.
https://doi.org/10.1182/blood-2022-159933
Published: 2022
Journal Articles

Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Clinical Trials & Observations
Murielle Roussel, Valérie Lauwers-Cances, Margaret Macro, Xavier Leleu, Bruno Royer, Cyrille Hulin, Lionel Karlin, Aurore Perrot, Cyrille Touzeau, Marie-Lorraine Chrétien, Sophie Rigaudeau, Mamoun Dib, Emmanuelle Nicolas-Virelizier, Martine Escoffre-Barbe, Karim Belhadj, Clara Mariette, Anne-Marie Stoppa, Carla Araujo, Chantal Doyen, Jean Fontan, Brigitte Kolb, Laurent Garderet, Sabine Brechignac, Jean-Valère Malfuson, Arnaud Jaccard, Pascal Lenain, Cécile Borel, Benjamin Hebraud, Omar Benbrahim, Véronique Dorvaux, Salomon Manier, Karine Augeul-Meunier, Marie-Christiane Vekemans, Edouard Randriamalala, Driss Chaoui, Jo Caers, Carine Chaleteix, Lofti Benboubker, Laure Vincent, Sylvie Glaisner, Patricia Zunic, Borhane Slama, Jean-Richard Eveillard, Catherine Humbrecht-Kraut, Véronique Morel, Philippe Mineur, Jean-Claude Eisenmann, Hélène Demarquette, Valentine Richez, Marguerite Vignon, Denis Caillot, Thierry Facon, Philippe Moreau, Anne-Laurène Colin, Pascale Olivier, Soraya Wuilleme, Hervé Avet-Loiseau, Jill Corre, Michel Attal
Journal: Blood
Blood (2022) 139 (18): 2747–2757.
https://doi.org/10.1182/blood.2021014635
Published: 2022
Includes: Supplemental data
Journal Articles

Phase II Study of the Combination of Pomalidomide with Dexamethasone As Maintenance Therapy after First Relapse Treatment with PCD Followed or Not By Autologous Stem Cell Transplant in Multiple Myeloma Patients

Laurent Garderet, Frédérique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric G. Voog, Lotfi Benboubker, Olivier Thierry Allangba, Eric Jourdan, Frédérique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2021) 138 (Supplement 1): 2753.
https://doi.org/10.1182/blood-2021-152136
Published: 2021
Journal Articles

Real-Life Survival Data after Triple-Exposure to Proteasome Inhibitors (PI), Immunomodulators (IMID) and Anti-CD38 in Multiple Myeloma Patients in the Emmy Cohort

Aurore Perrot, Cyrille Hulin, Margaret Macro, Laurent Frenzel, Carla Araujo, Philippe Moreau, Bruno Royer, Karim Belhadj, Denis Caillot, Xavier Leleu, Anne Vekhoff, Samantha Schulmann, Salomon Manier, Lionel Karlin, Laure Vincent, Sophie Rigaudeau, Driss Chaoui, Ronan Garlantezec, Nathalie Texier, Marion Willaime, Catherine Boccaccio, Olivier Decaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2021-149433
Published: 2021
Journal Articles

RD Vs. VRD: What Is the First-Line, Real-Life Management of Multiple Myeloma Patients Ineligible for Stem Cell Auto Transplantation in the Emmy Cohort?

Olivier Decaux, Aurore Perrot, Laurent Frenzel, Bruno Royer, Carla Araujo, Karim Belhadj, Philippe Moreau, Denis Caillot, Xavier Leleu, Agathe Farge, Anne Vekhoff, Samantha Schulmann, Jean Fontan, Frederique Orsini, Laurence Sanhes, Valentine Richez, Arnaud Jaccard, Ronan Garlantezec, Nathalie Texier, Raphael Germain, Catherine Boccaccio, Cyrille Hulin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3766.
https://doi.org/10.1182/blood-2021-149480
Published: 2021
Journal Articles

Maintenance with Weekly Carfilzomib in Elderly Newly Diagnosed Multiple Myeloma (IFM 2012-03)

Arthur Bobin, Guillemette Fouquet, Alain Duhamel, PU/PH, Salomon Manier, MD PhD, Lionel Karlin, MD, Brigitte Kolb, MD, Mourad Tiab, MD, Carla Araujo, MD, Nathalie Meuleman, PhD MD, Jean Valère Malfuson, MD, Pascal Bourquard, MD, Pascal Lenain, MD, Arnaud Jaccard, MD PhD, Karim Belhadj, MD, Michel Attal, MD PhD, Philippe Moreau, MD, Cyrille Hulin, MD, Xavier Leleu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3190.
https://doi.org/10.1182/blood-2019-131793
Published: 2019
Journal Articles

Pomalidomide, cyclophosphamide, and dexamethasone for relapsed multiple myeloma

Clinical Trials & Observations
Laurent Garderet, Frederique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric Voog, Lofti Benboubker, Olivier Allangba, Eric Jourdan, Frederique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean-Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2018) 132 (24): 2555–2563.
https://doi.org/10.1182/blood-2018-07-863829
Published: 2018
Includes: Supplemental data
Journal Articles

Light Chain Escape in Multiple Myeloma

Thomas Dejoie, MD, Guillemette Fouquet, Cyrille Hulin, Murielle Roussel, Benjamin Hebraud, Lionel Karlin, MD, Brigitte Kolb, MD, Carla Araujo, MD, Nathalie Meuleman, PhD MD, Mourad Tiab, MD, Jean Valère Malfuson, MD, Pascal Bourquard, MD, Pascal Lenain, MD, Arnaud Jaccard, MD PhD, Karim Belhadj, Gérard Lepeu, MD, Marie Lorraine Chretien, MD, Denis Caillot, Jean Fontan, MD, Philippe Rodon, MD, Anna Schmitt, Laurent Voillat, MD, Sophie Cereja, MD, Brigitte Pegourie, MD, Frederique Kuhnowski, MD, Sophie Rigaudeau, MD, Olivier Decaux, MD, Catherine Humbrecht-Kraut, MD, Jamilé Frayfer, MD, Laurent Garderet, Damien Roos-Weil, MD, Jean Claude Eisenmann, MD, Veronique Dorvaux, MD, Eric G. Voog, MD, Claire Mathiot, MD, Jean-Paul Fermand, MD, Thierry Facon, Hervé Avet-Loiseau, MD PhD, Jean Luc Harousseau, MD, Philippe Moreau, Michel Attal, MD PhD, Xavier Leleu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1881.
https://doi.org/10.1182/blood-2018-99-112396
Published: 2018
Journal Articles

Bortezomib and High-Dose Melphalan Vs. High-Dose Melphalan As Conditioning Regimen before Autologous Stem Cell Transplantation in De Novo Multiple Myeloma Patients: A Phase 3 Study of the Intergroupe Francophone Du Myelome (IFM 2014-02)

Murielle Roussel, Benjamin Hebraud, MD, Valerie Lauwers-Cances, MD, Margaret Macro, MD, Xavier Leleu, MD PhD, Cyrille Hulin, MD, Lionel Karlin, MD, Bruno Royer, MD, Aurore Perrot, MD, Philippe Moreau, MDPhD, Denis Caillot, MD, Sophie Rigaudeau, MD, Mamoun Dib, MD, Emmanuelle Nicolas-Virelizier, MD, Martine Escoffre-Barbe, MD, Karim Belhadj, MD, Brigitte Pegourie, MD, Anne-Marie Stoppa, MD, Carla Araujo, MD, Chantal Doyen, MD, Jean Fontan, MD, Brigitte Kolb, MD, Laurent Garderet, MD PhD, Sabine Brechignac, MD, Jean Valere Malfuson, MD, Veronique Dorvaux, MD, Pascal Lenain, MD, Omar Benbrahim, MD, Arnaud Jaccard, Cecile Borel, MD, Herve Avet Loiseau, MD PhD, Michel Attal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 398.
https://doi.org/10.1182/blood.V130.Suppl_1.398.398
Published: 2017
Journal Articles

Dynamic of Telomeric Parameters in Relapsing or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL), an Analysis of the Filo ICLL001 Bomp Trial

Laura Bounaix, Andrei Tchirkov, MD PhD, Florence Nguyen-Khac, MD PhD, Patricia Combes, Pierre Feugier, MD, Laurence Sanhes, Marie-Sarah Dilhuydy, MD, Hussam Saad, MD, Loic Ysebaert, MD PhD, Choquet Sylvain, Jean-Pierre Vilque, Annie Brion, Carla Araujo, MD, Emmanuelle Ferrant, Brigitte Dreyfus, Alain Jacques Delmer, MD, Malgorzata Truchan-Graczyk, Stéphane Leprêtre, MD, Sophie de Guibert, Romain Guieze, MD PhD, Lauren Veronese, MD PhD, Richard Lemal, MD, Philippe Vago, Jacques-Olivier Bay, MD PhD, Marc G. Berger, MD PhD, Anna Schuh, MD PhD, Christophe Ferrand, PhD, Roselyne Delepine, Véronique Leblond, Olivier Tournilhac, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4285.
https://doi.org/10.1182/blood.V130.Suppl_1.4285.4285
Published: 2017
Journal Articles

A Multicenter Open Label Phase II Study of Pomalidomide, Cyclophosphamide and Dexamethasone in Relapse Multiple Myeloma Patients Initially Treated with Lenalidomide, Bortezomib and Dexamethasone

Laurent Garderet, MD PhD, Frederique Kuhnowski, MD, jean Yves Mary, MD, Murielle Roussel, Martine Escoffre-Barbe, MD, Ingrid Lafon, MD, Thierry Facon, MD, Lionel Karlin, MD, Aurore Perrot, MD, Philippe Moreau, MDPhD, Gerald Marit, MD, Anne-Marie Stoppa, MD, Jean-Pierre Marolleau, MD PhD, Carine Chaleteix, MD, Mourad Tiab, Carla Araujo, MD, Pascal Lenain, MD, Margaret Macro, MD, Eric Voog, MD, Lofti Benboubker, MD, Olivier Allangba, MD, Eric Jourdan, MD, Mohamad Mohty, MD PhD, Herve Avet Loiseau, MD PhD, Claire Mathiot, MD, Michel Attal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 837.
https://doi.org/10.1182/blood.V130.Suppl_1.837.837
Published: 2017
Journal Articles

R-DHA-Oxaliplatin before Autologous Stem Cell Transplantation Prolongs PFS and OS As Compared to R-DHA-Carboplatin and R-DHA-Cisplatin in Patients with Mantle Cell Lymphoma, a Subgroup Analysis of the LyMa Trial

Steven Le Gouill, MD PhD, Catherine Thieblemont, MD PhD, Lucie Oberic, MD, Krimo Bouabdallah, MD, Emmanuel Gyan, MD PhD, Gandhi Damaj, MD, Thomas Gastinne, MD, Vincent Ribrag, Carla Araujo, MD, Eric Deconinck, MD PhD, Joel Fleury, MD, Pierre Morel, MD, Emmanuelle Nicolas-Virelizier, MD, Reda Bouabdallah, MD, Jamilé Frayfer, MD, Eric Jourdan, MD, Richard Delarue, MD, Laurence Sahnes, Alain Delmer, Anne Moreau, MD, Marie C Bene, PharmD,DPhil, Gilles Andre Salles, MD PhD, Herve Tilly, Thierry Lamy, Pr, MD PhD, Remy Gressin, MD, Olivier Hermine, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1496.
https://doi.org/10.1182/blood.V130.Suppl_1.1496.1496
Published: 2017
Journal Articles

Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma

CME
Thomas Dejoie, Jill Corre, Helene Caillon, Cyrille Hulin, Aurore Perrot, Denis Caillot, Eileen Boyle, Marie-Lorraine Chretien, Jean Fontan, Karim Belhadj, Sabine Brechignac, Olivier Decaux, Laurent Voillat, Philippe Rodon, Olivier Fitoussi, Carla Araujo, Lotfi Benboubker, Charlotte Fontan, Mourad Tiab, Pascal Godmer, Odile Luycx, Olivier Allangba, Jean-Michel Pignon, Jean-Gabriel Fuzibet, Laurence Legros, Anne Marie Stoppa, Mamoun Dib, Brigitte Pegourie, Frederique Orsini-Piocelle, Lionel Karlin, Bertrand Arnulf, Murielle Roussel, Laurent Garderet, Mohamad Mohty, Nathalie Meuleman, Chantal Doyen, Pascal Lenain, Margaret Macro, Xavier Leleu, Thierry Facon, Philippe Moreau, Michel Attal, Herve Avet-Loiseau
Journal: Blood
Blood (2016) 128 (25): 2941–2948.
https://doi.org/10.1182/blood-2016-07-726778
Published: 2016
Journal Articles

IFM2012-03

Xavier Leleu, Guillemette Fouquet, Lionel Karlin, MD, Brigitte Kolb, Mourad Tiab, Carla Araujo, Nathalie Meuleman, MD PhD, Jv Malfuson, Pascal Bourquard, MD, Pascal Lenain, Murielle Roussel, MD, Arnaud Jaccard, MD PhD, Marie-Odile Petillon, MD, Karim Belhadj-Merzoug, Gerard Lepeu, Marie-Lorraine Chretien, Jean Fontan, Philippe Rodon, MD, Anna Schmitt, MD, Fritz Offner, Laurent Voillat, Sophie Cereja, Frederique Kuhnowski, Sophie Rigaudeau, Olivier Decaux, MD PhD, Catherine Humbrecht-Kraut, Jamile Frayfer, MD, Olivier Fitoussi, MD, Damien Roos Weil, Jean Claude Eisenmann, MD, Veronique Dorvaux, Eric G. Voog, MD, Cyrille Hulin, Michel Attal, Philippe Moreau, Thierry Facon, MD
Journal: Blood
Blood (2016) 128 (22): 2128.
https://doi.org/10.1182/blood.V128.22.2128.2128
Published: 2016
Journal Articles

VTD is superior to VCD prior to intensive therapy in multiple myeloma: results of the prospective IFM2013-04 trial

Clinical Trials & Observations
Philippe Moreau, Cyrille Hulin, Margaret Macro, Denis Caillot, Carine Chaleteix, Murielle Roussel, Laurent Garderet, Bruno Royer, Sabine Brechignac, Mourad Tiab, Mathieu Puyade, Martine Escoffre, Anne-Marie Stoppa, Thierry Facon, Brigitte Pegourie, Driss Chaoui, Arnaud Jaccard, Borhane Slama, Gerald Marit, Karim Laribi, Pascal Godmer, Odile Luycx, Jean-Claude Eisenmann, Olivier Allangba, Mamoun Dib, Carla Araujo, Jean Fontan, Karim Belhadj, Marc Wetterwald, Véronique Dorvaux, Jean-Paul Fermand, Philippe Rodon, Brigitte Kolb, Sylvie Glaisner, Jean-Valere Malfuson, Pascal Lenain, Laetitia Biron, Lucie Planche, Helene Caillon, Herve Avet-Loiseau, Thomas Dejoie, Michel Attal
Journal: Blood
Blood (2016) 127 (21): 2569–2574.
https://doi.org/10.1182/blood-2016-01-693580
Published: 2016
Journal Articles

Bortezomib, Thalidomide and Dexamethasone (VTD) Is Superior to Bortezomib, Cyclophosphamide and Dexamethasone (VCD) Prior to Autologous Stem Cell Transplantation for Patients with De Novo Multiple Myeloma. Results of the Prospective IFM 2013-04 Trial

Philippe Moreau, Cyrille Hulin, Margaret MACRO, MD, Denis Caillot, Carine Chaleteix, Murielle Roussel, Laurent Garderet, MD, Bruno Royer, MD, Sabine Brechignac, MD, Mourad Tiab, MD, Mathieu Puyade, MD, Martine Escoffre, Anne-Marie Stoppa, MD, Thierry Facon, Brigitte Pégourie, Driss Chaoui, MD, Arnaud Jaccard, MD PhD, Borhane Slama, Gerald Marit, Kamel Laribi, Pascal Godmer, MD, Odile Luycx, Jean Claude Eisenmann, MD, Olivier Allangha, Sylvie Glaisner, Mamoun Dib, Carla Araujo, Jean Fontan, Karim Belhadj, MD, Marc Wetterwald, MD PhD, Veronique Dorvaux, Jean-Paul Fermand, Philippe Rodon, MD, Brigitte Kolb, Pascal Lenain, MD, Lucie Planche, Laetitia Biron, Helene Caillon, Herve Avet-Loiseau, Thomas Dejoie, Michel Attal
Journal: Blood
Blood (2015) 126 (23): 393.
https://doi.org/10.1182/blood.V126.23.393.393
Published: 2015