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Romain Guieze
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Journal Articles

Outcomes with Venetoclax-Based Treatment in Patients with Covalent Bruton Tyrosine Kinase Inhibitor (cBTKi)-Treated, Chemotherapy-Naïve Chronic Lymphocytic Leukemia (CLL): An International Retrospective Study

Paul J. Hampel, Kari G. Rabe, Romain Guieze, Yucai Wang, Emmanuelle Ferrant, Saad S. Kenderian, Marie Sarah Dilhuydy, Eli Muchtar, Anne-Sophie Michallet, Jose F. Leis, Luca Inchiappa, Mazie Tsang, Aline Clavert, Talal Hilal, Stephane Lepretre, Ricardo D. Parrondo, Emmanuelle Tchernonog, Amber Koehler, Lin Wang, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Luc-Matthieu Fornecker, Sameer A. Parikh, Loic Ysebaert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2024-198200
Published: 2024
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Final Results of the Eradic Trial from the Filo Group

Anne Sophie Michallet, Remi Letestu, Magali Legarff, Stéphane Morisset, Therese Aurran-Schleinitz, Kamel Laribi, Vincent Levy, Laurence Simon, Damien Roos Weil, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc-Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Omar Benbrahim, Xavier Cahu, Florence Nguyen Khac, Valerie Rouillé, Loic Ysebaert, Anne Quinquenel
Journal: Blood
Blood (2024) 144 (Supplement 1): 584.
https://doi.org/10.1182/blood-2024-194593
Published: 2024
Journal Articles

Valemetostat Monotherapy in Patients with Relapsed or Refractory Large B-Cell Lymphoma: Primary Results of the Phase 2 Valym Study from the Lysa

Emmanuel Bachy, Bernard Drenou, Fabrice Jardin, Keiko Nakajima, Katell Le Du, Gandhi Damaj, Fontanet Bijou, Borhane Slama, Gian Matteo Pica, Gaetan Vanstraelen, Charles Herbaux, Roch Houot, Francois Lemonnier, Julie Gay, Pierre Sujobert, Marguerite Fournier, Marlene Ochmann, Romain Guieze, Jorge Zeron, Alexandra Traverse-Glehen, Jean Marc Schiano De Colella, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2024-193960
Published: 2024
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Interim Results of MRD Kinetics in the Eradic Trial from the Filo Group

Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Tavernier Magali, Stéphane Morisset, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos Weil, Veronique Leblond, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valerie Rouillé, Alain Jacques Delmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2023-173341
Published: 2023
Journal Articles

Fms-like Tyrosine Kinase 3 Ligand Kinetic Profile Is the Strongest Factor Predicting Refractoriness after Induction and Event-Free Survival in Adults with AML: A Filo Prospective Multicentric Study

Pierre Peterlin, Joëlle Gaschet, Sarah Bertoli, Marc Bernard, Martin Carre, Pierre-Yves Dumas, Mathilde Hunault, Amine Belhabri, Anne Banos, Caroline Bonmati, Emmanuelle Tavernier, Gaelle Guillerm, Sarah Bonnet, Justine Decroocq, Alain Saad, Mario Ojeda-Uribe, Romain Guieze, Tony Marchand, Christian Recher, Alice Garnier, Marie-Anne Vibet, Patrice Chevallier
Journal: Blood
Blood (2023) 142 (Supplement 1): 975.
https://doi.org/10.1182/blood-2023-173518
Published: 2023
Journal Articles

Outcomes of CLL Patients Exposed to Venetoclax+/-R after Ibrutinib in France: The Resist Retrospective Study from the Filo-CLL Group

Loic Ysebaert, Emmanuelle Ferrant, Marie Sarah Dilhuydy, Anne-Sophie Michallet, Luca Inchiappa, Romain Guieze, Emmanuelle Tchernonog, Ana Cavillon, Marie Christine Bene, Luc-Matthieu Fornecker
Journal: Blood
Blood (2023) 142 (Supplement 1): 3273.
https://doi.org/10.1182/blood-2023-180696
Published: 2023
Journal Articles

Post-Transplant Lymphoproliferative Disorders (PTLD) in Real Life: Data from the French K-Virogref Registry on 525 Adult Patients

Antoine Tichadou, Elise Toussaint, Luc Matthieu Fornecker, Veronique Morel, Inès Boussen, Damien Roos Weil, Marine Baron, Madalina Uzunov, Laetitia Souchet, Louise Roulin, Nabih Azar, Stéphane Lepretre, Bijou Fontanet, Caroline Jacquet, Eric Durot, David Boutboul, Felipe Suarez, Thomas Cluzeau, Mohamed Touati, Emmanuel Bachy, Roch Houot, Fabrice Jardin, Romain Guieze, Loic Ysebaert, Laure Farnault de Lassus, Sylvain Choquet
Journal: Blood
Blood (2023) 142 (Supplement 1): 443.
https://doi.org/10.1182/blood-2023-189133
Published: 2023
Journal Articles

Tazemetostat in Combination with R-CHOP in Patients with High-Risk, Frontline Follicular Lymphoma (Epi-RCHOP): A Phase II Study from the Lysa

Loic Ysebaert, Francois Lemonnier, Gabriel Brisou, Olivier Casasnovas, Gian Matteo Pica, Emmanuel Bachy, Ludovic Fouillet, Julie Abraham, Stephanie Guidez, Marc André, Guillaume Cartron, Romain Guieze, Sylvain Carras, Benoit Tessoulin, Roch Houot, Bohrane Slama, Christophe Bonnet, Luc-Matthieu Fornecker, Marie-Helene Delfau, Clementine Sarkozy, Camille Laurent, Vincent Ribrag, Franck Morschhauser
Journal: Blood
Blood (2023) 142 (Supplement 1): 297.
https://doi.org/10.1182/blood-2023-185057
Published: 2023
Journal Articles

Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Gaspar Aspas Requena, Pierre Yves Dumas, Rebeca Rodriguez Veiga, Sarah Bertoli, Cristina Gil, Celestine Simand, Fernando Jesús Ramos-Ortega, Pierre Peterlin, Josefina Serrano, Rudy Birsen, Teresa Bernal Del Castillo, Emmanuelle Tavernier, Mar Tormo, Martin Carre, Maria Jose Garcia, Adrien Contejean, Rosalia Riaza Grau, Corentin Orvain, Jose Antonio Pérez-Simón, Esther Perez Santaolla, Lauren Veronese, Beatriz De Rueda Ciller, Eric Delabesse, Antonio Gutiérrez, Ariane Mineur, Adolfo De La Fuente Burguera, Romain Guieze, Arnaud Pigneux, Pau Montesinos, Christian Recher, David Matínez-Cuadrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 2864.
https://doi.org/10.1182/blood-2023-190128
Published: 2023
Journal Articles

CPX-351 in Patients with Newly Diagnosed Post Myeloproliferative Neoplasms Acute Myeloid Leukemia

Sylvain Garciaz, Amine Belhabri, Romain Guieze, Laure Goursaud, Pierre Peterlin, Marie-Pierre Ledoux, Hunault-Berger Mathilde, Safia Chebrek, Jean-Baptiste Robin, Arnaud Pigneux, Sarah Bonnet, Caroline Bonmati, Sarah Bertoli, Thorsten Braun, Sylvain Chantepie, Mathieu Meunier, Mael Heiblig, Thomas Cluzeau, Eric Jourdan, Alban Villate, Christian Recher, Norbert Vey, Jerome Rey
Journal: Blood
Blood (2023) 142 (Supplement 1): 2917.
https://doi.org/10.1182/blood-2023-184591
Published: 2023
Journal Articles

Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples

Jasneet Kaur Khalsa, Justin Cha, Filippo Utro, Aishath Naeem, Ishwarya Murali, Yanan Kuang, Kevin Vasquez, Liang Li, Svitlana Tyekucheva, Stacey M. Fernandes, Lauren Veronese, Romain Guieze, Binu Kandathilparambil Sasi, Zixu Wang, John-Hanson Machado, Harrison Bai, Maryam Alasfour, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Matthew S. Davids, Cloud P. Paweletz, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown
Journal: Blood
Blood (2023) 142 (5): 421–433.
https://doi.org/10.1182/blood.2022016600
Published: 2023
Includes: Supplemental data
Journal Articles

ZNF683 (Hobit) Marks a CD8+ T Cell Population Associated with Anti-Tumor Immunity Following Anti-PD-1 Therapy for Richter Syndrome

Camilla K Lemvigh, Erin Michelle Parry, Stephanie L Deng, Nathan J Dangle, Neil Ruthen, Binyamin A. Knisbacher, Julien Broséus, Sébastien Hergalant, Romain Guieze, Shuqiang Li, Shanye Yin, Teddy Huang, Kenneth J Livak, Gad Getz, Donna S. Neuberg, Pierre Feugier, Peter Kharchenko, William G. Wierda, Lars Rønn Olsen, Nitin Jain, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1807–1808.
https://doi.org/10.1182/blood-2022-162550
Published: 2022
Journal Articles

Dexaml-02 : A Phase II Study of Dexamethasone Added to Induction and Postremission Therapy in Older Patients with Newly Diagnosed AML. a French Innovative Leukemia Organization (FILO) Study

Christian Recher, Sarah Bertoli, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Yosr Hicheri, Omar Benbrahim, Martin Carre, Hunault-Berger Mathilde, Anne Banos, Marc Bernard, Emmanuel Gyan, Alain Saad, Safia Chebrek, Gabrielle Roth Guepin, Veronique Dorvaux, Laurence Sanhes, Maria Pilar Gallego Hernanz, Carole Exbrayat, Laure Vincent, Chantal Himberlin, Laetitia Largeaud, Eric Delabesse, Francois Vergez, Norbert Vey, Ariane C Mineur, Célestine Simand, Isabelle Luquet, Arnaud Pigneux
Journal: Blood
Blood (2022) 140 (Supplement 1): 6149–6151.
https://doi.org/10.1182/blood-2022-158665
Published: 2022
Journal Articles

Gilteritinib Activity in Refractory or Relapsed FLT3 -Mutated Acute Myeloid Leukemia Patients Previously Treated By Intensive Chemotherapy and Midostaurin: A Study from the French AML Intergroup ALFA/Filo

Pierre-Yves Dumas, Emmanuel Raffoux, Emilie Berard, Sarah Bertoli, Marie Anne Hospital, Mael Heiblig, Yohan Desbrosses, Caroline Bonmati, Cecile Pautas, Juliette Lambert, Corentin Orvain, Anne Banos, Florence Pasquier, Pierre Peterlin, Tony Marchand, Madalina Uzunov, Jamilé Frayfer, Pascal Turlure, Thomas Cluzeau, Eric Jourdan, Chantal Himberlin, Emmanuelle Tavernier, Alban Villate, Stéphanie Haiat, Marie-Lorraine Chretien, Martin Carre, Sylvain Chantepie, Iona Vaida, Mathieu Wemeau, Safia Chebrek, Gaëlle Guillerm, Romain Guieze, Houria Debarri, Eve Gehlkopf, Kamel Laribi, Ambroise Marçais, Alberto Santagostino, Marie C Bene, Ariane C Mineur, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 8996–8998.
https://doi.org/10.1182/blood-2022-159125
Published: 2022
Journal Articles

Combined Treatment with Ibrutinib and Anti-CD38 Monoclonal Antibody Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia with TP53 Aberrations: Results of the Filo Phase II Study IDA53

Therese Aurran-Schleinitz, Cécile Tomowiak, Damien Roos-Weil, Emmanuelle Ferrant, Béatrice Mahé, Lysiane Molina, Loic Ysebaert, Luc Mathieu Fornecker, Anne-Sophie Michallet, Vincent Levy, Romain Guieze, Alain Delmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 7030–7031.
https://doi.org/10.1182/blood-2022-163096
Published: 2022
Journal Articles

Epag 2015 : A Phase II Randomized Placebo-Controlled Study to Assess the Impact on Outcome of Eltrombopag Administered to Elderly Patients with Acute Myeloid Leukemia Receiving Induction Chemotherapy. a French Innovative Leukemia Organization (FILO) Study

Arnaud Pigneux, Pierre-Yves Dumas, Marc Bernard, Norbert Vey, Audrey Bidet, Ariane Mineur, Mathilde Hunault, Martin Carre, Mario Ojeda, Anne Banos, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Gabrielle Roth Guepin, Celestine Simand, Thibaut Leguay, Emmanuel Gyan, Eric Jourdan, Jean-Philippe Vial, Tony Marchand, Yosr Hicheri, Marie C Bene, Jean Francois Hamel, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 6142–6144.
https://doi.org/10.1182/blood-2022-167000
Published: 2022
Journal Articles

Anti-CD19 CAR T-Cell Therapy for Patients with Richter Syndrome: A Lysa Study from the Descar-T Registry

Hedi Bensaber, Emmanuel Bachy, David Beauvais, Remy Dulery, Thomas Gastinne, Bruno Villemagne, Louise Roulin, Etienne Paubelle, Cristina Castilla-Llorente, Thomas Longval, Elodie Gat, Amandine Fayard, Jacques-Olivier Bay, Steven Le Gouill, Roch Houot, Romain Guieze
Journal: Blood
Blood (2022) 140 (Supplement 1): 3803–3804.
https://doi.org/10.1182/blood-2022-158807
Published: 2022
Journal Articles

Preliminary Results of the Filo Phase 2 Trial for Untreated Fit Patients with Intermediate Risk Chronic Lymphocytic Leukemia Comparing Ibrutinib Plus Venetoclax (IV) Versus FCR: Results of the Month 15 MRD Evaluation

Anne Quinquenel, Rémi Letestu, Magali Le Garff-Tavernier, Fabien Subtil, Therese Aurran-Schleinitz, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos-Weil, Véronique Leblond, Marie-Sarah Dilhuydy, Caroline Dartigeas, Cecile Tomowiak, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie de Guibert, Pierre Feugier, Fatiha Merabet, Stephane Lepretre, Philippe Carassou, Julie Gay, Bénédicte Hivert, Luc Mathieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valérie Rouille, Alain Delmer, Anne-Sophie Michallet
Journal: Blood
Blood (2022) 140 (Supplement 1): 7007–7009.
https://doi.org/10.1182/blood-2022-159678
Published: 2022
Journal Articles

Real-World Efficacy and Safety of Venetoclax Alone and in Combination with Rituximab in Patients with Chronic Lymphocytic Leukemia: Interim Results of the Verone Study

Loic Ysebaert, Xavier Troussard, Vincent Levy, Ronan Le Calloch, Romain Guieze, Kamel Laribi, Stephane Lepretre, Anne-Sophie Michallet, Véronique Leblond, Pierre Feugier, Elhem Lahjibi, Julien Ramier, Alain Delmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 12395–12396.
https://doi.org/10.1182/blood-2022-162319
Published: 2022
Journal Articles

Evolutionary History of Transformation from Chronic Lymphocytic Leukemia to Richter Syndrome

Erin Michelle Parry, Romain Guieze, Ignaty Leshchiner, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla K Lemvigh, Julien Broséus, Sébastien Hergalant, Connor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Shuqiang Li, Geoffrey G Fell, Robert A. Redd, Ziao Lin, Binyamin A. Knisbacher, Christof Schneider, Stacey M. Fernandes, Julian M. Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William G. Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S. Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1530–1533.
https://doi.org/10.1182/blood-2022-160335
Published: 2022