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Saad S. Kenderian
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Journal Articles

Lisocabtagene Maraleucel (liso-cel) in Patients (pts) with Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Updated Follow-up of Transcend CLL 004

Tanya Siddiqi, Jordan Gauthier, Saad S. Kenderian, Danielle M. Brander, Kathleen Dorritie, Jacob D. Soumerai, Peter A. Riedell, Nirav N. Shah, Rajneesh Nath, Charalambos Andreadis, Daniel A. Ermann, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Sherilyn A. Tuazon, Serena K. Perna, San-San Ou, Neha Rane, Eniko Papp, Yizhe Chen, William G. Wierda
Journal: Blood
Blood (2024) 144 (Supplement 1): 4633.
https://doi.org/10.1182/blood-2024-200840
Published: 2024
Journal Articles

Serum Immunoglobulins Are an Independent Prognostic Marker of Time to First Therapy in Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) and Monoclonal B-Cell Lymphocytosis (MBL)

Yuan Yao, Kari G. Rabe, Cristine Allmer, Geffen Kleinstern, Nicholas J. Boddicker, Shulan Tian, Laura A. Bruins, Daniel R. O'Brien, Aaron D. Norman, Huihuang Yan, Timothy G. Call, Paul J. Hampel, Yucai Wang, Eli Muchtar, Saad S. Kenderian, Neil E. Kay, Celine M. Vachon, James R. Cerhan, Susan L. Slager, Esteban Braggio, Sameer A. Parikh
Journal: Blood
Blood (2024) 144 (Supplement 1): 4616.
https://doi.org/10.1182/blood-2024-194925
Published: 2024
Journal Articles

Intrinsic Immunosuppressive Features of Monocytes Suppress CART19 through IL-1 Pathway Modulation in Mantle Cell Lymphoma

Kun Yun, R. Leo Sakemura, Ismail Can, Omar Gutierrez Ruiz, Ekene Ogbodo, Shuwen Zhang, Truc Huynh, Claudia Manriquez Roman, Olivia L. Sirpilla, Carli M. Stewart, James H. Girsch, Jennifer M. Feigin, Long K. Mai, Hong Xia, Brooke L. Kimball, Lionel A Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Fariborz Rakhshan Rohakhtar, Vernadette Simon, Elizabeth L. Siegler, Mike Mattie, Sao-Mai Nguyen-Mau, Simone Filosto, Saad S. Kenderian
Journal: Blood
Blood (2024) 144 (Supplement 1): 908.
https://doi.org/10.1182/blood-2024-205905
Published: 2024
Journal Articles

Caspase-1 Inhibition Ameliorates CAR T-Cell Apoptosis and Tumor Cell Pyroptosis to Enhance the Efficacy and Safety of CAR T-Cell Therapy

Wannakorn Khopanlert, Truc Huynh, Brooke L. Kimball, Grace E. DeFranco, Sophia Y. Goldberg, Dominic A. Skeele, Jennifer M. Feigin, James H. Girsch, Olivia L. Sirpilla, Carli M. Stewart, Kun Yun, Claudia Manriquez Roman, Ismail Can, Omar Gutierrez Ruiz, Ekene Ogbodo, Long K. Mai, Hong Xia, Mehrdad Hefazi, Lionel Aurelien Kankeu Fonkoua, Michael W. Ruff, Elizabeth L. Siegler, Saad S. Kenderian, R. Leo Sakemura
Journal: Blood
Blood (2024) 144 (Supplement 1): 907.
https://doi.org/10.1182/blood-2024-202661
Published: 2024
Journal Articles

Distinct Functional Impacts of Cytokine Receptor Blockade on CART Cells

Kun Yun, Evandro Bezerra, R. Leo Sakemura, Emmanuel Contreras Guzman, Ismail Can, Omar Gutierrez Ruiz, Ekene Ogbodo, Truc Huynh, Claudia Manriquez Roman, Olivia L. Sirpilla, Carli M. Stewart, Jennifer M. Feigin, Grace E. DeFranco, Sophia Y. Goldberg, Dominic A. Skeele, Long K. Mai, Hong Xia, Brooke L. Kimball, Lionel A Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2024) 144 (Supplement 1): 7166.
https://doi.org/10.1182/blood-2024-211119
Published: 2024
Journal Articles

Cytokine Profile Comparisons Among Cytokine Release Syndrome (CRS), Macrophage Activation-like Syndrome (MAS-L) and Immune Effector Cell-Associated Hemophagocytic Syndrome (IEC-HS) in CAR-T Therapy

Supriya Gupta, Andre Corraes, Hassan B Alkhateeb, Alice Gallo de Moraes, Paschalis Vergidis, Radhika Bansal, Saad S. Kenderian, Urshila Durani, Jonas Paludo, Arushi Khurana, Joselle Cook, N. Nora Bennani, Jose C. Villasboas Bisneto, Mithun V Shah, Taxiarchis Kourelis, Nadine Abdallah, Yucai Wang, Morie A. Gertz, Rahma M Warsame, Suzanne R Hayman, Prashant Kapoor, Stephen M. Ansell, Shaji Kumar, David Dingli, Tyler B. Sandahl, Adrienne N. Nedved, Jason Barreto, Robert C Wolf, Patrick B. Johnston, Yi Lin, Nelson Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 7165.
https://doi.org/10.1182/blood-2024-211111
Published: 2024
Journal Articles

Outcomes with Venetoclax-Based Treatment in Patients with Covalent Bruton Tyrosine Kinase Inhibitor (cBTKi)-Treated, Chemotherapy-Naïve Chronic Lymphocytic Leukemia (CLL): An International Retrospective Study

Paul J. Hampel, Kari G. Rabe, Romain Guieze, Yucai Wang, Emmanuelle Ferrant, Saad S. Kenderian, Marie Sarah Dilhuydy, Eli Muchtar, Anne-Sophie Michallet, Jose F. Leis, Luca Inchiappa, Mazie Tsang, Aline Clavert, Talal Hilal, Stephane Lepretre, Ricardo D. Parrondo, Emmanuelle Tchernonog, Amber Koehler, Lin Wang, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Luc-Matthieu Fornecker, Sameer A. Parikh, Loic Ysebaert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2024-198200
Published: 2024
Journal Articles

Lisocabtagene Maraleucel (liso-cel) Combined with Ibrutinib (ibr) for Patients (pts) with Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Primary Results from the Open-Label, Phase 1/2 Transcend CLL 004 Study

William G. Wierda, Kathleen Dorritie, Jordan Gauthier, Rajneesh Nath, Thomas J. Kipps, Peter A. Riedell, Herbert A. Eradat, Saad S. Kenderian, Mohamed A. Kharfan-Dabaja, Nirav N. Shah, Scott R. Solomon, Daniel A. Ermann, Jon E. Arnason, Abhinav Deol, Tatyana Feldman, Charalambos Andreadis, Monalisa Ghosh, Shuo Ma, Stephen J. Schuster, Usama Gergis, Julie M. Vose, Jacob D. Soumerai, Koen van Besien, Sherilyn A. Tuazon, Serena K. Perna, San-San Ou, Neha Rane, Eniko Papp, Yizhe Chen, Tanya Siddiqi
Journal: Blood
Blood (2024) 144 (Supplement 1): 887.
https://doi.org/10.1182/blood-2024-200339
Published: 2024
Journal Articles

Correlation between Pre-Apheresis Biomarkers and Development of Severe Cytopenias and Therapy-Related Myeloid Neoplasms in Non-Hodgkin Lymphoma Patients Undergoing Chimeric Antigen Receptor T-Cell Therapy

Andre De Menezes Silva Corraes, Anmol Baranwal, Radhika Bansal, Mark Gurney, Allison C. Rosenthal, Mohamed A. Kharfan-Dabaja, Arushi Khurana, Patrick B. Johnston, Stephen M. Ansell, Prashant Kapoor, Morie A. Gertz, Shaji Kumar, David Dingli, Urshila Durani, Jose C. Villasboas Bisneto, Saad S. Kenderian, Hassan B Alkhateeb, Yi Lin, Yucai Wang, Mithun V Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 2372.
https://doi.org/10.1182/blood-2024-210474
Published: 2024
Journal Articles

Real World Outcomes with Evolving Management of Cytokine Release Syndrome in CAR-T Therapy

Radhika Bansal, Andre Corraes, Monica Shaw, Lucy Holmes, Allison Kosobud, Kelsey L Haugen, Arushi Khurana, Paul J. Hampel, Urshila Durani, Suzanne R Hayman, Yucai Wang, Moritz Binder, Jonas Paludo, Saad S. Kenderian, N. Nora Bennani, Patrick B. Johnston, Stephen M. Ansell, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 2274.
https://doi.org/10.1182/blood-2024-203370
Published: 2024
Journal Articles

Identification of T Cell Senescence As a Cell Fate Limiting the Antitumor Activity of 41BB-Costimulated CART Cells

Ismail Can, R. Leo Sakemura, Olivia L. Sirpilla, Claudia Manriquez Roman, Carli M. Stewart, Kun Yun, Truc Huynh, Ekene Ogbodo, Lionel A Kankeu Fonkoua, Jennifer M. Feigin, Omar Gutierrez Ruiz, Long K. Mai, Hong Xia, Brooke L. Kimball, Mehrdad Hefazi, Michael W. Ruff, Elizabeth L. Siegler, H. Atakan Ekiz, Berke Alkan, Fatih Sezer, Saad S. Kenderian
Journal: Blood
Blood (2024) 144 (Supplement 1): 4808.
https://doi.org/10.1182/blood-2024-207818
Published: 2024
Journal Articles

CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS

R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Elizabeth L. Siegler, James H. Girsch, Olivia L. Sirpilla, Carli M. Stewart, Kun Yun, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Brooke L. Kimball, Long K. Mai, Truc N. Huynh, Wendy K. Nevala, Kristina Ilieva, Christian Augsberger, Maria Patra-Kneuer, Jürgen Schanzer, Jan Endell, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Saad S. Kenderian
Journal: Blood
Blood (2024) 143 (3): 258–271.
https://doi.org/10.1182/blood.2022018905
Published: 2024
Includes: Supplemental data
Journal Articles

Chronic Lymphoproliferative Disorder of Natural Killer Cells: Patient Characteristics, Laboratory Features, and Clinical Outcomes

Richard C. Godby, Kari G. Rabe, Steven R. Hwang, Hadiyah Audil, Susan L. Slager, Saad S. Kenderian, Neil E. Kay, Yucai Wang, Paul J Hampel, Sameer A. Parikh, Wei Ding, Min Shi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4446.
https://doi.org/10.1182/blood-2023-182545
Published: 2023
Journal Articles

Affinity of Anti-CD19 Antibodies Determines Subsequent CART19 Activation, Apoptosis and CRS in Preclinical Models

R. Leo Sakemura, Claudia Manriquez Roman, Long K. Mai, Brooke L. Kimball, Truc Huynh, Jennifer M. Feigin, James H. Girsch, Olivia L. Sirpilla, Kun Yun, Carli M. Stewart, Omar Gutierrez Ruiz, Ismail Can, Ekene Ogbodo, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Jan Jaehrling, Kristina Ilieva, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2023) 142 (Supplement 1): 6796.
https://doi.org/10.1182/blood-2023-179408
Published: 2023
Journal Articles

Cytokine Release Syndrome Results in Reduced AML Killing By CD123 CAR T Cells

Anand S Bhagwat, Leonel Torres, Olga Shestova, Maksim Shestov, Noelle V. Frey, Elizabeth O Hexner, Selina M Luger, Alison W Loren, Mary Ellen Martin, Shannon R McCurdy, Alexander Perl, Edward A. Stadtmauer, James K. Mangan, Jennifer Brogdon, Joseph A Fraietta, Wei-Ting Hwang, Don L. Siegel, Saad S. Kenderian, David L. Porter, Carl June, Saar Gill
Journal: Blood
Blood (2023) 142 (Supplement 1): 217.
https://doi.org/10.1182/blood-2023-182104
Published: 2023
Journal Articles

Lisocabtagene Maraleucel (liso-cel) in R/R CLL/SLL: 24-Month Median Follow-up of TRANSCEND CLL 004

Tanya Siddiqi, David G Maloney, Saad S. Kenderian, Danielle M Brander, Kathleen Dorritie, Jacob Soumerai, Peter A Riedell, Nirav N. Shah, Rajneesh Nath, Bita Fakhri, Deborah M. Stephens, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Serena K. Perna, Sherilyn A. Tuazon, San-San Ou, Neha Rane, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 330.
https://doi.org/10.1182/blood-2023-179529
Published: 2023
Journal Articles

Early Predictors of Severe Cytopenia Post CAR-T for Identification of Patients for Potential Stem Cell Collection

Andre De Menezes Silva Corraes, Radhika Bansal, Larissa Argenau Marques Brunaldi, Sikander Ailawadhi, Arushi Khurana, Paul J Hampel, Urshila Durani, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yucai Wang, Moritz Binder, Saad S. Kenderian, Taxiarchis Kourelis, Rahma M Warsame, N. Nora Bennani, Morie A. Gertz, Patrick B Johnston, Stephen M Ansell, Rafael Fonseca, P. Leif Bergsagel, Shaji Kunnathu Kumar, Ricardo Parrondo, Saurabh Chhabra, Yi Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 6927.
https://doi.org/10.1182/blood-2023-189683
Published: 2023
Journal Articles

Incidence of Richter Transformation in Patients with Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL): A Cohort Study Evaluating Different Therapeutic Eras

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Steven R Hwang, Saad S. Kenderian, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Wei Ding, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2023-185076
Published: 2023
Journal Articles

Outpatient Management of CAR-T and Teclistamab for Patients with Lymphoma and Multiple Myeloma

Radhika Bansal, Jonas Paludo, Andre Corraes, Megan Spychalla, Kelsey Haugen, Arushi Khurana, Paul J. Hampel, Urshila Durani, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yucai Wang, Moritz Binder, Saad S. Kenderian, Taxiarchis Kourelis, Shaji Kunnathu Kumar, Rahma M Warsame, N. Nora Bennani, Morie A. Gertz, Patrick B Johnston, Stephen M Ansell, Yi Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 253.
https://doi.org/10.1182/blood-2023-187186
Published: 2023
Journal Articles

Clinical Outcomes with Venetoclax-Based Treatment Regimens in Patients with Chronic Lymphocytic Leukemia (CLL)

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Saad S. Kenderian, Wei Ding, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3276.
https://doi.org/10.1182/blood-2023-183007
Published: 2023