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Journal Articles

Distinct Functional Impacts of Cytokine Receptor Blockade on CART Cells

Blood (2024) 144 (Supplement 1): 7166.

https://doi.org/10.1182/blood-2024-211119

Published: 2024

Journal Articles

Identification of T Cell Senescence As a Cell Fate Limiting the Antitumor Activity of 41BB-Costimulated CART Cells

Blood (2024) 144 (Supplement 1): 4808.

https://doi.org/10.1182/blood-2024-207818

Published: 2024

Journal Articles

Intrinsic Immunosuppressive Features of Monocytes Suppress CART19 through IL-1 Pathway Modulation in Mantle Cell Lymphoma

Blood (2024) 144 (Supplement 1): 908.

https://doi.org/10.1182/blood-2024-205905

Published: 2024

Journal Articles

Caspase-1 Inhibition Ameliorates CAR T-Cell Apoptosis and Tumor Cell Pyroptosis to Enhance the Efficacy and Safety of CAR T-Cell Therapy

Blood (2024) 144 (Supplement 1): 907.

https://doi.org/10.1182/blood-2024-202661

Published: 2024

Journal Articles

Affinity of Anti-CD19 Antibodies Determines Subsequent CART19 Activation, Apoptosis and CRS in Preclinical Models

Blood (2023) 142 (Supplement 1): 6796.

https://doi.org/10.1182/blood-2023-179408

Published: 2023

Journal Articles

Identification of IL-4 As a Key Regulator of CAR T-Cell Exhaustion Using Functional Genomics and Correlates of the Zuma-1 Clinical Trial

Carli M. Stewart, Michelle J. Cox, Reona Leo Sakemura, Ekene J. Ogbodo, Ismail Can, Claudia Manriquez-Roman, Kun Yun, Olivia Sirpilla, James H. Girsch, Truc Huynh, Elizabeth L. Siegler, Jenny J Kim, Mike Mattie, Nathalie Scholler, Simone Filosto, Saad S. Kenderian

Blood (2022) 140 (Supplement 1): 4536–4537.

https://doi.org/10.1182/blood-2022-160219

Published: 2022

Journal Articles

Immunosuppressive Monocyte Modulation of CAR T Cell Functions and Impact on Response to CART19

Kun Yun, Reona Leo Sakemura, Michelle J. Cox, Truc Huynh, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, James H. Girsch, Ekene J. Ogbodo, Ismail Can, Brooke Kimball, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Elizabeth L. Siegler, Mike Mattie, Sao-Mai Nguyen-Mau, Simone Filosto, Saad S. Kenderian

Blood (2022) 140 (Supplement 1): 10263–10264.

https://doi.org/10.1182/blood-2022-164706

Published: 2022

Journal Articles

Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models

Olivia Sirpilla, Reona Leo Sakemura, Mehrdad Hefazi, James H. Girsch, Truc Huynh, Michelle J. Cox, Kendall J. Schick, Claudia Manriquez-Roman, Ismail Can, Kun Yun, Carli M. Stewart, Ekene J. Ogbodo, Elizabeth L. Siegler, Saad S. Kenderian

Blood (2022) 140 (Supplement 1): 1579–1580.

https://doi.org/10.1182/blood-2022-158872

Published: 2022

Journal Articles

Differential Susceptibility to Senescence in CART Cells Based on Co-Stimulatory Signaling

Ismail Can, Reona Leo Sakemura, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, Kun Yun, Michelle J. Cox, Truc Huynh, James H. Girsch, Ekene J. Ogbodo, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Justin C. Boysen, Elizabeth L. Siegler, Atakan Ekiz, Saad S. Kenderian, Neil E. Kay

Blood (2022) 140 (Supplement 1): 8600–8601.

https://doi.org/10.1182/blood-2022-163446

Published: 2022

Journal Articles

CD19 Antigen Occupancy on Cancer Cells with the CD19 Monoclonal Antibody Tafasitamab Improves the Activation, Antitumor Efficacy, and Safety Profile of CART19 Cell Therapy

Blood (2022) 140 (Supplement 1): 2362–2364.

https://doi.org/10.1182/blood-2022-158273

Published: 2022

Journal Articles

Targeting a Dominant Negative Splice Variant of TRAIL to Enhance CART Cell Functions

Ismail Can, Sekar Natesampillai, Reona Leo Sakemura, Elizabeth L. Siegler, Claudia Manriquez-Roman, Shahrzad Jalali, Truc Huynh, Ashton Krogman, Mark Maynes, Andrew D. Badley, Saad S. Kenderian, Mehrdad Hefazi

Blood (2022) 140 (Supplement 1): 632–633.

https://doi.org/10.1182/blood-2022-163677

Published: 2022

NARROW

Distinct Functional Impacts of Cytokine Receptor Blockade on CART Cells

Identification of T Cell Senescence As a Cell Fate Limiting the Antitumor Activity of 41BB-Costimulated CART Cells

Intrinsic Immunosuppressive Features of Monocytes Suppress CART19 through IL-1 Pathway Modulation in Mantle Cell Lymphoma

Caspase-1 Inhibition Ameliorates CAR T-Cell Apoptosis and Tumor Cell Pyroptosis to Enhance the Efficacy and Safety of CAR T-Cell Therapy

Affinity of Anti-CD19 Antibodies Determines Subsequent CART19 Activation, Apoptosis and CRS in Preclinical Models

Identification of IL-4 As a Key Regulator of CAR T-Cell Exhaustion Using Functional Genomics and Correlates of the Zuma-1 Clinical Trial

Immunosuppressive Monocyte Modulation of CAR T Cell Functions and Impact on Response to CART19

Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models

Differential Susceptibility to Senescence in CART Cells Based on Co-Stimulatory Signaling

CD19 Antigen Occupancy on Cancer Cells with the CD19 Monoclonal Antibody Tafasitamab Improves the Activation, Antitumor Efficacy, and Safety Profile of CART19 Cell Therapy

Targeting a Dominant Negative Splice Variant of TRAIL to Enhance CART Cell Functions

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American Society of Hematology

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American Society of Hematology

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