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Journal Articles

Racial and ethnic disparities in u.S. chronic lymphocytic leukemia clinical trial enrollment: A participation-to-prevalence analysis

Free
Anushka Bhaskar, Anna Oh, William Shomali, Gabriel Mannis, Michaela Liedtke, Jason Gotlib, Tait Shanafelt, Bita Fakhri
Journal: Blood
Blood (2025) 146 (Supplement 1): 6308.
https://doi.org/10.1182/blood-2025-6308
Published: 2025
Journal Articles

Novel therapeutics for SF3B1 mutant cancers which exploit the missplicing of DCAF16

Free
Michal Sekrecki, Agata Sekrecka, Rohan Lattupally, Kenny Le, Xunhong Cao, Vicky Chen, Zhe Zhuang, Brendan Dwyer, Crystal Zhou, Charu Tiwari, Austin Gabel, Won Jun Kim, Robert Stanley, Salima Benbarche, Jose Pineda, Nathanael Gray, Tian Zhang, Peter Greenberg, Jason Gotlib, Gabriel Mannis, William Shomali, Giselle Salmasi, Tait Shanafelt, Capucine van Rechem, Xiaoyu Zhang, Bita Fakhri, Sydney Lu
Journal: Blood
Blood (2025) 146 (Supplement 1): 1474.
https://doi.org/10.1182/blood-2025-1474
Published: 2025
Journal Articles

The predictive value of mosaic chromosomal alterations for lymphoid malignancies varies by monoclonal B-cell lymphocytosis status

Free
Rosalie Griffin, Tait Shanafelt, Sameer Parikh, Nicholas Boddicker, Kari Rabe, Cristine Allmer, Aaron Norman, Yuan Yao, Bryan Vallejo, Stacey Lehman, Janet Olson, Yucai Wang, Lindsey Roeker, Paul Hampel, Esteban Braggio, Mrinal Patnaik, Celine Vachon, James Cerhan, Curtis Hanson, Susan Slager
Journal: Blood
Blood (2025) 146 (Supplement 1): 3545.
https://doi.org/10.1182/blood-2025-3545
Published: 2025
Journal Articles

Ibrutinib enhances 41BB-costimulated CART19 function and persistence through immune reprogramming: Insights from the phase 3 ECOG-ACRIN E1912 clinical Trial

Free
Truc Huynh, Victoria Wang, Jennifer Feigin, Elizabeth Siegler, Brooke Kimball, Carli Stewart, Kun Yun, Long Mai, Claudia Manriquez Roman, Hong Xia, R. Leo Sakemura, Ismail Can, Omar Gutierrez Ruiz, Ekene Ogbodo, Olivia Sirpilla, Grace DeFranco, Sophia Goldberg, Ateka Saleh, Dominic Skeele, Sara Foote, Yoh Yamaguchi, Lionel Kankeu Fonkoua, Mehrdad Hefazi Torghabeh, Sameer Parikh, Vitoria Cantinho Pereira, Paul Buckley, Alan Ramsay, Tait Shanafelt, Neil Kay, Saad Kenderian
Journal: Blood
Blood (2025) 146 (Supplement 1): 2101.
https://doi.org/10.1182/blood-2025-2101
Published: 2025
Journal Articles

Non-CLL-type MBL and chip are associated precursor conditions: Insights from Mayo Clinic's MBL screening cohort

Free
Yuan Yao, Tait Shanafelt, Sameer Parikh, Paul Hampel, Lindsey Roeker, Yucai Wang, Aaron Norman, Kari Rabe, Janet Olson, Rosalie Griffin, Soren Basnet, Dennis Robinson, Mingma Hoel, Bryan Vallejo, Alyssa Clay-Gilmour, Stacey Lehman, Mrinal Patnaik, Timothy Call, James Cerhan, Celine Vachon, Neil Kay, Esteban Braggio, Curtis Hanson, Nicholas Boddicker, Susan Slager
Journal: Blood
Blood (2025) 146 (Supplement 1): 128.
https://doi.org/10.1182/blood-2025-128
Published: 2025
Journal Articles

Prevalence and Overall Survival of Low Count Monoclonal B-Cell Lymphocytosis (LC-MBL): A Screening Study of 8,297 Individuals from the Mayo Clinic Biobank

Free
Susan L. Slager, Sameer A. Parikh, Sara J. Achenbach, Geffen Kleinstern, Nicholas J. Boddicker, Aaron D. Norman, Kari G. Rabe, Connie E. Lesnick, Timothy G. Call, Janet E. Olson, James R. Cerhan, Neil E. Kay, Celine M. Vachon, Esteban Braggio, Curtis A. Hanson, Tait Shanafelt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2021-153320
Published: 2021
Journal Articles

Quality of Life in Patients <=70 Years of Age with Chronic Lymphocytic Leukemia Treated Frontline with Ibrutinib-Rituximab Versus Fludarabine Cyclophosphamide Rituximab: Analysis from ECOG-ACRIN E1912

Free
Priyanka A Pophali, Xin Victoria Wang, Fengmin Zhao, Neil E. Kay, Curtis A. Hanson, Mary L. Thomas, Susan M. O'Brien, Jacqueline Barrientos, Elisabeth M. Paietta, Jose F. Leis, Cong Christine Zhang, Steven Coutre, Paul M. Barr, Amanda Cashen, Anthony R. Mato, Avina Singh, Richard F. Little, Harry P. Erba, Richard M. Stone, Mark R. Litzow, Martin S. Tallman, Tait Shanafelt, Lynne I. Wagner
Journal: Blood
Blood (2021) 138 (Supplement 1): 1562.
https://doi.org/10.1182/blood-2021-150462
Published: 2021
Journal Articles

Relationship and Susceptibility to Serious Infections Among Monoclonal B-Cell Lymphocytosis (MBL), Monoclonal Gammopathy of Undetermined Significance (MGUS), and Clonal Hematopoiesis (CH) Premalignant Conditions

Free
Nicholas J. Boddicker, Sameer A. Parikh, Geffen Kleinstern, Aaron D. Norman, Kari G. Rabe, Timothy G. Call, Janet E. Olson, Angela Dispenzieri, David L Murray, S. Vincent Rajkumar, Shaji Kumar, James R. Cerhan, Neil E. Kay, Esteban Braggio, Curtis A. Hanson, Tait Shanafelt, Celine M. Vachon, Susan L. Slager
Journal: Blood
Blood (2021) 138 (Supplement 1): 3739.
https://doi.org/10.1182/blood-2021-151929
Published: 2021
Journal Articles

Long-Term Efficacy of First-Line Ibrutinib Treatment for Chronic Lymphocytic Leukemia (CLL) With 4 Years of Follow-Up in Patients With TP53 Aberrations (del(17p) or TP53 Mutation): A Pooled Analysis From 4 Clinical Trials

Free
John N. Allan, MD, Tait Shanafelt, MD, Adrian Wiestner, MD PhD, Carol Moreno, MD PhD, Susan M. O'Brien, MD, Esteban Braggio, PhD, Emily Liu, MS, James P. Dean, MD PhD, Dominic Lai, PharmD, Inhye E. Ahn, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-134431
Published: 2020
Journal Articles

Polygenic Risk Score and Risk of Chronic Lymphocytic Leukemia, Monoclonal B-Cell Lymphocytosis (MBL), and MBL Subtypes

Free
Geffen Kleinstern, PhD, J. Brice Weinberg, MD, Sameer A. Parikh, MD, Esteban Braggio, PhD, Dennis P. Robinson, Aaron D. Norman, MPH, Kari G Rabe, Celine M. Vachon, PhD, Connie E. Lesnick, Timothy G. Call, MD, Danielle M. Brander, MD, Janet E. Olson, PhD, James R. Cerhan, MD PhD, Neil E. Kay, MD, Curtis A. Hanson, MD, Richard R. Furman, MD, Tait Shanafelt, MD, Susan L. Slager, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-136548
Published: 2020
Journal Articles

Clinical Characteristics and Outcomes of Newly Diagnosed Patients with Chronic Lymphocytic Leukemia Who Are 80 Years of Age or Older

Free
Paul J. Hampel, MD, Timothy G. Call, MD, Kari G Rabe, Sara J. Achenbach, Eli Muchtar, MD, Saad S. Kenderian, MB, ChB, Yucai Wang, MDPhD, Amber B. Koehler, PA-C, MS, Jose F. Leis, MD PhD, Susan M. Schwager, Daniel L. Van Dyke, PhD, Min Shi, MDPhD, Curtis A. Hanson, MD, Tait Shanafelt, MD, Esteban Braggio, PhD, Susan L. Slager, PhD, Neil E. Kay, MD, Wei Ding, MD PhD, Sameer A. Parikh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-137578
Published: 2020
Journal Articles

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

Free
Clinical Trials & Observations Brief Report
Panagiotis Baliakas, Andreas Agathangelidis, Anastasia Hadzidimitriou, Lesley-Ann Sutton, Eva Minga, Athina Tsanousa, Lydia Scarfò, Zadie Davis, Xiao-Jie Yan, Tait Shanafelt, Karla Plevova, Yorick Sandberg, Fie Juhl Vojdeman, Myriam Boudjogra, Tatiana Tzenou, Maria Chatzouli, Charles C. Chu, Silvio Veronese, Anne Gardiner, Larry Mansouri, Karin E. Smedby, Lone Bredo Pedersen, Denis Moreno, Kirsten Van Lom, Véronique Giudicelli, Hana Skuhrova Francova, Florence Nguyen-Khac, Panagiotis Panagiotidis, Gunnar Juliusson, Lefteris Angelis, Achilles Anagnostopoulos, Marie-Paule Lefranc, Monica Facco, Livio Trentin, Mark Catherwood, Marco Montillo, Christian H. Geisler, Anton W. Langerak, Sarka Pospisilova, Nicholas Chiorazzi, David Oscier, Diane F. Jelinek, Nikos Darzentas, Chrysoula Belessi, Frederic Davi, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos
Journal: Blood
Blood (2015) 125 (5): 856–859.
https://doi.org/10.1182/blood-2014-09-600874
Published: 2015
Includes: Supplemental data
Journal Articles

Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia

Free
Juhi Ojha, Jackline Ayres, Charla Secreto, Renee Tschumper, Kari Rabe, Daniel Van Dyke, Susan Slager, Tait Shanafelt, Rafael Fonseca, Neil E. Kay, Esteban Braggio
Journal: Blood
Blood (2015) 125 (3): 492–498.
https://doi.org/10.1182/blood-2014-06-580563
Published: 2015
Includes: Supplemental data
Journal Articles

Charting Unique Signatures of Somatic Hypermutation Amongst Chronic Lymphocytic Leukemia Patients Expressing IGHV4-34 Clonotypic B Cell Receptors

Free
Aliki Xochelli, Ioannis Kavakiotis, Andreas Agathangelidis, Dirk Kienle, Zadie Davis, Xiao J. Yan, Tait Shanafelt, Myriam Boudjogra, Karla Plevova, Maria Chatzouli, Lone Bredo Pedersen, Silvio Veronese, Monica Facco, Denis Moreno, Charles C Chu, Veronique Giudicelli, Panagiotis Panagiotidis, Ioannis Vlahavas, Achilles Anagnostopoulos, Nikolaos Maglaveras, Livio Trentin, Mark Catherwood, Marco Montillo, Christian H. Geisler, Anton W Langerak, Sarka Pospisilova, Marie-Paule Lefranc, Nicholas Chiorazzi, MD, David Oscier, Diane F. Jelinek, Stephan Stilgenbauer, MD, Chrysoula Belessi, Paolo Ghia, Frederic Davi, Richard Rosenquist, Nikos Darzentas, Ioanna Chouvarda, Lesley-Ann Sutton, Anastasia Hadzidimitriou, Kostas Stamatopoulos
Journal: Blood
Blood (2014) 124 (21): 1969.
https://doi.org/10.1182/blood.V124.21.1969.1969
Published: 2014
Journal Articles

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL

Free
Anna Vardi, Antonis Dagklis, Lydia Scarfò, Diane Jelinek, Darren Newton, Fiona Bennett, Julia Almeida, Arancha Rodriguez-Caballero, Sallie Allgood, Mark Lanasa, Agostino Cortelezzi, Ester Orlandi, Silvio Veronese, Marco Montillo, Andy Rawstron, Tait Shanafelt, Alberto Orfao, Kostas Stamatopoulos, Paolo Ghia
Journal: Blood
Blood (2013) 121 (22): 4521–4528.
https://doi.org/10.1182/blood-2012-12-471698
Published: 2013
Includes: Supplemental data
Journal Articles

Infectious Complications In a Prospective Cohort of Community Based Newly Diagnosed Patients with Chronic Lymphocytic Leukemia (CLL).

Free
Jonathan Moreira, MD, Timothy Call, MD, Kari Rabe, Randy Wendt, Clive S. Zent, MD, Neil E. Kay, MD, Deborah Bowen, Jose Leis, MD, Susan Slager, PhD, Jon Wilson, MD, Tait Shanafelt, MD
Journal: Blood
Blood (2010) 116 (21): 4610.
https://doi.org/10.1182/blood.V116.21.4610.4610
Published: 2010
Journal Articles

Longitudinal Genomic Analyses In Chronic Lymphocytic Leukemia (CLL) Patients Reveal Clonal Relationship and Genomic Evolution In Disease Progression and After Therapy

Free
Esteban Braggio, Neil E. Kay, Scott Van Wier, Stephanie Smoley, Jeanette Eckel-Passow, Traci Sassoon, Daniel L. Van Dyke, PhD, Diane F. Jelinek, PhD, Tait Shanafelt, MD, Renee Tschumper, Mike Barrett, Thomas J. Kipps, MD, PhD, John C. Byrd, MD, Rafael Fonseca
Journal: Blood
Blood (2010) 116 (21): 3605.
https://doi.org/10.1182/blood.V116.21.3605.3605
Published: 2010
Journal Articles

Stromal Rescue of Drug Exposed CLL Cells Can Be Overcome by the Green Tea Extract Epigallocatechin 3 Gallate

Free
Connie 1Lesnick, Neil E. Kay, Betsy LaPlant, Tait Shanafelt, MD
Journal: Blood
Blood (2010) 116 (21): 3610.
https://doi.org/10.1182/blood.V116.21.3610.3610
Published: 2010
Journal Articles

Survival of Patients with Clinically Identified Monoclonal B-Cell Lymphocytosis (MBL) Relative to the Age and Sex Matched General Population

Free
Tait Shanafelt, MD, Neil E. Kay, Kari Rabe, Timothy Call, MD, Clive S. Zent, MD, Susan Schwager, Jose Leis, Diane F. Jelinek, PhD, Susan Slager, PhD, Curtis Hanson
Journal: Blood
Blood (2010) 116 (21): 700.
https://doi.org/10.1182/blood.V116.21.700.700
Published: 2010
Journal Articles

A Novel Receptor Tyrosine Kinase Axl is Constitutively Active in B-Cell Chronic Lymphocytic Leukemia and Acts as a Docking Site of Non-Receptor Kinases: Implications for Therapy

Free
Asish K Ghosh, PhD, Charla Secreto, Justin Boysen, Traci Sassoon, Sacha Holland, Tait Shanafelt, MD, Debabrata Mukhopadhyay, Neil E. Kay
Journal: Blood
Blood (2010) 116 (21): 54.
https://doi.org/10.1182/blood.V116.21.54.54
Published: 2010