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Journal Articles

Evaluation of Revised International Staging System for Transplant-Eligible Multiple Myeloma Patients

Veronica Gonzalez-Calle, MD, Abigail Slack, Susan Luft, M.S., R.N., Kathryn Pearce, Rhett P. Ketterling, MD, Tania Jain, M.B., B.S, Sinto Sebastian Chirackal, PhD, Craig B. Reeder, MD, Joseph Mikhael, MD, Leif Bergsagel, MD, Pierre Noel, MD, Angela Mayo, P.A.-C., M.S., James L. Slack, MD, Roberta H. Adams, MD, Gregory Ahmann, Esteban Braggio, PhD, Keith Stewart, M.B., Ch.B., Scott Van Wier, Rafael Fonseca, MD

Blood (2016) 128 (22): 3452.

https://doi.org/10.1182/blood.V128.22.3452.3452

Published: 2016

Journal Articles

Complementary Activation of Ccnd, MYC, RAS and NFkB By Mutations in Multiple Myeloma

Kristine Misund, PhD, Niamh Keane, MD, Yan W Asmann, PhD, Scott Van Wier, Daniel Riggs, PhD, Gregory Ahmann, Marta Chesi, PhD, K. Martin Körtum, MD, Rafael Fonseca, MD, A. Keith Stewart, MD, Esteban Braggio, PhD, P. Leif Bergsagel, MD

Blood (2016) 128 (22): 355.

https://doi.org/10.1182/blood.V128.22.355.355

Published: 2016

Journal Articles

Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN)

Sinto Sebastian Chirackal, PhD, Esteban Braggio, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Scott Van Wier, Gregory Ahmann, Veronica Gonzalez-Calle, MD, Marta Chesi, PhD, Leif Bergsagel, MD, Keith Stewart, M.B., Ch.B., Rafael Fonseca, MD

Blood (2016) 128 (22): 4482.

https://doi.org/10.1182/blood.V128.22.4482.4482

Published: 2016

Journal Articles

Development Of a 47 Gene Sequencing Panel For Common Mutations Present In Multiple Myeloma : Preliminary Results In 77 p53 Deleted Patients

K. Martin Kortuem, MD, Christian Langer, MD, Esteban Braggio, Ph.D., Scott Van Wier, Jan Egan, PhD, Laura Bruins, Jessica Schmidt, Lars Bullinger, MD, PhD, Miriam Kull, MD, Stefan Knop, MD, Hermann Einsele, MD, A. Keith Stewart, MBA, MB, CHB

Blood (2013) 122 (21): 4449.

https://doi.org/10.1182/blood.V122.21.4449.4449

Published: 2013

Journal Articles

Genomic Landscape and Clonal Heterogeneity Underlying Progression and Relapse In Chronic Lymphocytic Leukemia (CLL)

Juhi Ojha, PhD, Jackline Ayres-Silva, Charla Secreto, Scott Van Wier, Susan L Slager, PhD, Rafael Fonseca, M.D., Tait D Shanafelt, MD, Neil E. Kay, MD, Esteban Braggio, Ph.D.

Blood (2013) 122 (21): 2855.

https://doi.org/10.1182/blood.V122.21.2855.2855

Published: 2013

Journal Articles

The Genomic Landscape Of Primary Central Nervous System Lymphomas

Esteban Braggio, Ph.D., Brian Patrick O'Neill, MD, Scott Van Wier, Juhi Ojha, PhD, Jackline ayres-Silva, Riccardo Valdez, MD, Jan Egan, PhD, Ellen McPhail, MD, Maria Beatriz Lopes, David Schiff, MD, Raoul Tibes, MD, Keith Stewart, MBA, MB, CHB, Rafael Fonseca, M.D.

Blood (2013) 122 (21): 504.

https://doi.org/10.1182/blood.V122.21.504.504

Published: 2013

Journal Articles

Promiscuous Cryptic Rearrangements of the MYC Locus Cis-Dysregulate MYC Expression and Are Present in the Majority of Patients with Hyperdiploid Myeloma

P Leif Bergsagel, MD, Maurizio Affer, PhD, Oleg K Glebov, PhD, Wei-Dong D Chen, PhD, Jonathan J Keats, PhD, Leslie A Brents, Marta Chesi, PhD, Scott Van Wier, Sandra K Badar, Rafael Fonseca, MD, W Michael Kuehl, MD

Blood (2012) 120 (21): 724.

https://doi.org/10.1182/blood.V120.21.724.724

Published: 2012

Journal Articles

Clonal competition with alternating dominance in multiple myeloma

Jonathan J. Keats, Marta Chesi, Jan B. Egan, Victoria M. Garbitt, Stephen E. Palmer, Esteban Braggio, Scott Van Wier, Patrick R. Blackburn, Angela S. Baker, Angela Dispenzieri, Shaji Kumar, S. Vincent Rajkumar, John D. Carpten, Michael Barrett, Rafael Fonseca, A. Keith Stewart, P. Leif Bergsagel

Blood (2012) 120 (5): 1067–1076.

https://doi.org/10.1182/blood-2012-01-405985

Published: 2012

Includes: Supplemental data

Journal Articles

Comprehensive High-Resolution Studies Differentiate and Characterize Hypodiploid Multiple Myeloma

Scott Van Wier, Esteban Braggio, PhD, Rafael Fonseca, MD

Blood (2011) 118 (21): 2869.

https://doi.org/10.1182/blood.V118.21.2869.2869

Published: 2011

Journal Articles

Longitudinal Genome Wide Analysis of Patients with Chronic Lymphocytic Leukemia Reveals Complex Evolution of Clonal Architecture At Disease Progression and At the Time of Relapse

Esteban Braggio, PhD, Neil Kay, MD, Scott Van Wier, Renee C. Tschumper, Stephanie A. Smoley, Jeanette E. Eckel-Passow, Ph.D., Traci Sassoon, Daniel L. Van Dyke, Ph.D., John C. Byrd, MD, Diane F. Jelinek, Ph.D., Tait D. Shanafelt, MD, Rafael Fonseca, MD

Blood (2011) 118 (21): 2838.

https://doi.org/10.1182/blood.V118.21.2838.2838

Published: 2011

Journal Articles

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Laura A. Bruins, Jessica E. Schmidt, Scott Van Wier, Xiu-Bao Chang, Chad C. Bjorklund, Rafael Fonseca, P. Leif Bergsagel, Robert Z. Orlowski, A. Keith Stewart

Blood (2011) 118 (18): 4771–4779.

https://doi.org/10.1182/blood-2011-05-356063

Published: 2011

Includes: Supplemental data

Journal Articles

Longitudinal Genomic Analyses In Chronic Lymphocytic Leukemia (CLL) Patients Reveal Clonal Relationship and Genomic Evolution In Disease Progression and After Therapy

Esteban Braggio, Neil E. Kay, Scott Van Wier, Stephanie Smoley, Jeanette Eckel-Passow, Traci Sassoon, Daniel L. Van Dyke, PhD, Diane F. Jelinek, PhD, Tait Shanafelt, MD, Renee Tschumper, Mike Barrett, Thomas J. Kipps, MD, PhD, John C. Byrd, MD, Rafael Fonseca

Blood (2010) 116 (21): 3605.

https://doi.org/10.1182/blood.V116.21.3605.3605

Published: 2010

Journal Articles

Analysis of Serial Patient Samples Reveals a Variety of Clonal Dynamics In Multiple Myeloma

Jonathan J Keats, PhD, Esteban Braggio, Scott Van Wier, Patrick Blackburn, BS, Angela Baker, Michael Barrett, John Carpten, Rafael Fonseca, Keith Stewart, MBA, MB, CHB, P. Leif Bergsagel

Blood (2010) 116 (21): 1923.

https://doi.org/10.1182/blood.V116.21.1923.1923

Published: 2010

Journal Articles

Progressive but Previously Untreated CLL Patients with Greater Array CGH Complexity Exhibit A Less Durable Response to Chemoimmunotherapy

Neil E. Kay, Jeanette Eckel Passow, Esteban Braggio, Scott Van Wier, Tait Shanafelt, Daniel L. Van Dyke, PhD, Diane F. Jelinek, PhD, Renee Tschumper, Thomas J. Kipps, MD, PhD, John C. Byrd, MD, Rafael Fonseca

Blood (2010) 116 (21): 2406.

https://doi.org/10.1182/blood.V116.21.2406.2406

Published: 2010

Journal Articles

Impact of IgVH Gene Mutational Status and VH Family Usage on Chromosomal Aberrations Detected by High-Resolution Array-CGH in B-CLL.

Jose F Leis, MD, PhD, Esteban Braggio, PhD, Scott Van Wier, Jonathan J Keats, PhD, Diane F. Jelinek, PhD, Daniel van Dyke, Clive S. Zent, MD, Tait D. Shanafelt, M.D., Timothy G Call, MD, Neil E. Kay, MD, Rafael Fonseca

Blood (2009) 114 (22): 1246.

https://doi.org/10.1182/blood.V114.22.1246.1246

Published: 2009

Journal Articles

Association of High Levels of Free Light Chain and the Presence of Igh Translocations in Multiple Myeloma and Prognostic Implications.

Shaji Kumar, Lijun Zhang, Angela Dispenzieri, Scott Van Wier, Jerry Katzmann, Melissa Snyder, Emily Blood, Roberta DeGoey, Kim Henderson, Arthur Bradwell, Robert Kyle, Philip Greipp, S. Vincent Rajkumar, Rafael Fonseca

Blood (2008) 112 (11): 1677.

https://doi.org/10.1182/blood.V112.11.1677.1677

Published: 2008

Journal Articles

Loss of p53 Is a Marker of Progression in Plasma Cell Neoplasias and Is a Negative Prognostic Factor in Relapsed Disease.

Soledad Molnar, MD, Victor J Jimenez Zepeda, Scott Van Wier, Esteban Braggio, Jonathan Keats, Michael Kuehl, Tammy Price-Troska, Greg Ahmann, Rachel Rempel, Kim Henderson, MD, S. Vincent Rajkumar, MD, Philip. R Greipp, MD, Daniel Auclair, John Carpten, Angela Baker, Keith Stewart, MD, P. Leif Bergsagel, MD, Wee Joo Chng, MD, Rafael Fonseca, MD

Blood (2008) 112 (11): 1663.

https://doi.org/10.1182/blood.V112.11.1663.1663

Published: 2008

Journal Articles

TRAF3 and TNFAIP3, Two Negative Regulators of NF-Kb Signaling Pathways, Are Mutated in Waldenström’s Macroglobulinemia

Blood (2008) 112 (11): 619.

https://doi.org/10.1182/blood.V112.11.619.619

Published: 2008

Journal Articles

Inactivation of Tumor Necrosis Factor 3 Gene (TRAF3) Is Frequently Identified in Waldenström’s Macroglobulinemia Patients.

Esteban Braggio, PhD, Jonathan J. Keats, PhD, Scott Van Wier, Tammy Price-Troska, Kimberly Henderson, Marta Chesi, PhD, John Carpten, PhD, Leif P. Bergsagel, MD, Rafael Fonseca, MD

Blood (2007) 110 (11): 2476.

https://doi.org/10.1182/blood.V110.11.2476.2476

Published: 2007

Journal Articles

Comparative High Resolution Array-Based CGH (aCGH) in B-Cell Malignancies.

Esteban Braggio, PhD, Jonathan J. Keats, PhD, Wee-Joo Chng, MD, Victor H. Jimenez, MD, Roelandt Schop, MD, Alexander Sekulik, MD, PhD, Angela Baker, Scott Van Wier, Tammy Price-Troska, Michael Barrett, PhD, John Carpten, PhD, Ellen Remstein, MD, Ahmet Dogan, MD, Leif P. Bergsagel, MD, Rafael Fonseca, MD

Blood (2007) 110 (11): 2479.

https://doi.org/10.1182/blood.V110.11.2479.2479

Published: 2007

NARROW

Evaluation of Revised International Staging System for Transplant-Eligible Multiple Myeloma Patients

Complementary Activation of Ccnd, MYC, RAS and NFkB By Mutations in Multiple Myeloma

Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN)

Development Of a 47 Gene Sequencing Panel For Common Mutations Present In Multiple Myeloma : Preliminary Results In 77 p53 Deleted Patients

Genomic Landscape and Clonal Heterogeneity Underlying Progression and Relapse In Chronic Lymphocytic Leukemia (CLL)

The Genomic Landscape Of Primary Central Nervous System Lymphomas

Promiscuous Cryptic Rearrangements of the MYC Locus Cis-Dysregulate MYC Expression and Are Present in the Majority of Patients with Hyperdiploid Myeloma

Clonal competition with alternating dominance in multiple myeloma

Comprehensive High-Resolution Studies Differentiate and Characterize Hypodiploid Multiple Myeloma

Longitudinal Genome Wide Analysis of Patients with Chronic Lymphocytic Leukemia Reveals Complex Evolution of Clonal Architecture At Disease Progression and At the Time of Relapse

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

Longitudinal Genomic Analyses In Chronic Lymphocytic Leukemia (CLL) Patients Reveal Clonal Relationship and Genomic Evolution In Disease Progression and After Therapy

Analysis of Serial Patient Samples Reveals a Variety of Clonal Dynamics In Multiple Myeloma

Progressive but Previously Untreated CLL Patients with Greater Array CGH Complexity Exhibit A Less Durable Response to Chemoimmunotherapy

Impact of IgVH Gene Mutational Status and VH Family Usage on Chromosomal Aberrations Detected by High-Resolution Array-CGH in B-CLL.

Association of High Levels of Free Light Chain and the Presence of Igh Translocations in Multiple Myeloma and Prognostic Implications.

Loss of p53 Is a Marker of Progression in Plasma Cell Neoplasias and Is a Negative Prognostic Factor in Relapsed Disease.

TRAF3 and TNFAIP3, Two Negative Regulators of NF-Kb Signaling Pathways, Are Mutated in Waldenström’s Macroglobulinemia

Inactivation of Tumor Necrosis Factor 3 Gene (TRAF3) Is Frequently Identified in Waldenström’s Macroglobulinemia Patients.

Comparative High Resolution Array-Based CGH (aCGH) in B-Cell Malignancies.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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