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Journal Articles

CLL with Mutated IGHV4-34 Antigen Receptors Is Clinically Heterogeneous: Antigen Receptor Stereotypy Makes the Difference

Aliki Xochelli, Panagiotis Baliakas, Andreas Agathangelidis, Anastasia Hadzidimitriou, Lesley-Ann Sutton, Eva Minga, Eugen Tausch, MD, Xiao J. Yan, Tait D. Shanafelt, MD, Karla Plevova, PhD, Myriam Boudjogra, Davide Rossi, MD PhD, Zadie Davis, Alba Navarro, Yorick Sandberg, Fie Juhl Vojdeman, Lydia Scarfo, Niki Stavroyianni, Andrey B. Sudarikov, PhD, Silvio Veronese, Tatiana Tzenou, MD, Teodora Karan-Djurasevic, Mark Catherwood, PhD, Dirk Kienle, Maria Chatzouli, Monica Facco, MS, Jasmin Bahlo, Lone Bredo Pedersen, Larry Mansouri, Karin E Smedby, MD PhD, Charles C Chu, Véronique Giudicelli, Marie-Paule Lefranc, Panagiotis Panagiotidis, Gunnar Juliusson, Achilles Anagnostopoulos, Darko Antic, Livio Trentin, Marco Montillo, Carsten Niemann, Hartmut Döhner, MD, Anton W. Langerak, Nikos Darzentas, Sarka Pospisilova, Michael Hallek, MD, Elias Campo, Nicholas Chiorazzi, MD, David Oscier, Gianluca Gaidano, MD PhD, Chrysoula Belessi, Diane F. Jelinek, Stephan Stilgenbauer, MD, Frederic Davi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos

Blood (2015) 126 (23): 5263.

https://doi.org/10.1182/blood.V126.23.5263.5263

Published: 2015

Journal Articles

Charting Unique Signatures of Somatic Hypermutation Amongst Chronic Lymphocytic Leukemia Patients Expressing IGHV4-34 Clonotypic B Cell Receptors

Blood (2014) 124 (21): 1969.

https://doi.org/10.1182/blood.V124.21.1969.1969

Published: 2014

Journal Articles

Telomere length in mantle cell lymphoma

Billy Michael Chelliah Jebaraj, Dirk Kienle, André Lechel, Daniel Mertens, Maria Heuberger, German Ott, Andreas Rosenwald, Thomas F. E. Barth, Peter Möller, Thorsten Zenz, Hartmut Döhner, Stephan Stilgenbauer

Blood (2013) 121 (7): 1184–1187.

https://doi.org/10.1182/blood-2012-08-452649

Published: 2013

Includes: Supplemental data

Journal Articles

Telomere Length in Mantle Cell Lymphoma.

Billy Michael Chelliah Jebaraj, M.Sc., Dirk Kienle, MD, German Ott, MD, Andreas Rosenwald, MD, Thomas F.E. Barth, Peter Möller, MD, Thorsten Zenz, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD

Blood (2012) 120 (21): 2509.

https://doi.org/10.1182/blood.V120.21.2509.2509

Published: 2012

Journal Articles

miR-34a as part of the resistance network in chronic lymphocytic leukemia

Thorsten Zenz, Julia Mohr, Eric Eldering, Arnon P. Kater, Andreas Bühler, Dirk Kienle, Dirk Winkler, Jan Dürig, Marinus H. J. van Oers, Daniel Mertens, Hartmut Döhner, Stephan Stilgenbauer

Blood (2009) 113 (16): 3801–3808.

https://doi.org/10.1182/blood-2008-08-172254

Published: 2009

Includes: Supplemental data

Journal Articles

Quantitative Gene Expression Analysis of Surrogate Markers for Genetic Risk Groups and Survival in CLL

Dirk Kienle, Axel Benner, Dirk Winkler, Manfred Hensel, M.D., Riccardo Dalla-Favera, Peter Lichter, Stephan Stilgenbauer, MD, PhD, Hartmut Döhner

Blood (2008) 112 (11): 4170.

https://doi.org/10.1182/blood.V112.11.4170.4170

Published: 2008

Journal Articles

Mir-34a as Part of the Chemotherapy Resistance Network in Chronic Lymphocytic Leukemia.

Thorsten Zenz, Julia Mohr, Eric Eldering, Arnon P Kater, Andreas Bühler, Dirk Winkler, Dirk Kienle, Jan Dürig, Daniel Mertens, Hartmut Döhner, Stephan Stilgenbauer

Blood (2008) 112 (11): 1209.

https://doi.org/10.1182/blood.V112.11.1209.1209

Published: 2008

Journal Articles

17p Deletion in CLL: Detailed Analysis of TP53 Mutations, Alternative Mechanisms of p53 Inactivation, Clone Size and Clonal Evolution

Thorsten Zenz, Antonio Sarno, Sonja Häbe, Tina Denzel, Julia Mohr, Dominik Vollmer, Maria Heuberger, Dirk Winkler, Dirk Kienle, Andreas Bühler, Sim Truong, Nancy Patten, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer

Blood (2008) 112 (11): 782.

https://doi.org/10.1182/blood.V112.11.782.782

Published: 2008

Journal Articles

Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia

Göran Roos, Alexander Kröber, Pawel Grabowski, Dirk Kienle, Andreas Bühler, Hartmut Döhner, Richard Rosenquist, Stephan Stilgenbauer

Blood (2008) 111 (4): 2246–2252.

https://doi.org/10.1182/blood-2007-05-092759

Published: 2008

Journal Articles

Clonal Evolution in Chronic Lymphocytic Leukemia: Acquisition of High-Risk Genomic Aberrations Associated with Unmutated VH, Resistance to Therapy, and Short Survival.

Stephan Stilgenbauer, MD, Sandrine Sander, MD, Lars Bullinger, MD, Axel Benner, MD, Elke Leupolt, MD, Dirk Winkler, Alexander Kröber, Dirk Kienle, Peter Lichter, Hartmut Döhner

Blood (2006) 108 (11): 296.

https://doi.org/10.1182/blood.V108.11.296.296

Published: 2006

Journal Articles

Array-CGH Based Genomic Profiling in B-Cell Chronic Lymphocytic Leukemia Reveals Specific Correlations of Genomic Imbalances and Prognostic Subgroups and Underlines the Consistency of Chromosomal Aberration Patterns within This Disease.

Carsten Schwaenen, MD, Dirk Kienle, MD, Alexander Krober, MD, Sandra Ruf, Dirk Winkler, MD, Holger Kohlhammer, MD, Hans A. Kestler, PhD, Peter Lichter, PhD, Swen Wessendorf, MD, Hartmut Dohner, MD, Stephan Stilgenbauer, MD

Blood (2006) 108 (11): 2083.

https://doi.org/10.1182/blood.V108.11.2083.2083

Published: 2006

Journal Articles

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in V H 3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status

Blood (2006) 107 (7): 2889–2894.

https://doi.org/10.1182/blood-2005-06-2227

Published: 2006

Includes: Supplemental data

Journal Articles

Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes

Dirk Kienle, Axel Benner, Alexander Kröber, Dirk Winkler, Daniel Mertens, Andreas Bühler, Till Seiler, Ulrich Jäger, Peter Lichter, Hartmut Döhner, Stephan Stilgenbauer

Blood (2006) 107 (5): 2090–2093.

https://doi.org/10.1182/blood-2005-04-1483

Published: 2006

Includes: Supplemental data

Journal Articles

17p Deletion Predicts for Inferior Overall Survival after Fludarabine - Based First Line Therapy in Chronic Lymphocytic Leukemia: First Analysis of Genetics in the CLL4 Trial of the GCLLSG.

Stephan Stilgenbauer, MD, Alexander Kröber, MD, Raymonde Busch, PhD, Barabara Eichhorst, MD, Dirk Kienle, MD, Dirk Winkler, MD, Georg Hopfinger, MD, Peter Lichter, MD, Bertold Emmerich, MD, Michael Hallek, MD, Hartmut Döhner, MD, The GCLLSG

Blood (2005) 106 (11): 715.

https://doi.org/10.1182/blood.V106.11.715.715

Published: 2005

Journal Articles

The Paternally Expressed Gene 10 (PEG10) on Chromosome 7q21 Is Overexpressed and Imprinted in High-Risk B-CLL.

Blood (2005) 106 (11): 1221.

https://doi.org/10.1182/blood.V106.11.1221.1221

Published: 2005

Journal Articles

Strikingly Homologous Immunoglobulin Gene Rearrangements and Poor Outcome in V H 3-21-Utilizing Chronic Lymphocytic Leukemia Independent of Geographical Origin and Mutational Status.

Fiona Murray, Mia Thorselius, Alexander Krober, Ulf Thunberg, Gerard Tobin, Andreas Buhler, Dirk Kienle, Emilia Albesiano, Lan-Phuong Dao-Ung, James Wiley, Juhani Vilpo, Anna Laurell, Goran Roos, Karin Karlsson, Nicholas Chiorazzi, Roberto Marasca, Hartmut Dohner, Stephan Stilgenbauer, Richard Rosenquist

Blood (2005) 106 (11): 175.

https://doi.org/10.1182/blood.V106.11.175.175

Published: 2005

Journal Articles

Subcutaneous Campath-1H (Alemtuzumab) in Fludarabine-Refractory Cll: Interim Analysis of the CLL2h Study of the German Cll Study Group (GCLLSG).

Stephan Stilgenbauer, MD, Dirk Winkler, MD, Alexander Kröber, MD, Dirk Kienle, MD, Michael Hallek, MD, Manfred Hensel, MD, Eva Lengfelder, MD, Lorenz Trümper, MD, Peter Dreger, MD, Ulrich Jäger, MD, Hartmut Döhner, MD, the GCLLSG

Blood (2004) 104 (11): 478.

https://doi.org/10.1182/blood.V104.11.478.478

Published: 2004

Journal Articles

ZAP-70 Expression, VH-Mutation Status, Genomic Aberrations and Prognosis in Chronic Lymphocytic Leukemia.

Alexander Kröber, Dirk Kienle, Dirk Winkler, Andreas Bühler, Till Seiler, Christine Schöpflin, Sabrina Kless, Claire Paulus, Hartmut Döhner, Stephan Stilgenbauer

Blood (2004) 104 (11): 1920.

https://doi.org/10.1182/blood.V104.11.1920.1920

Published: 2004

Journal Articles

High ZAP-70 and Differential Expression of B-Cell Receptor Related Genes in Chronic Lymphocytic Leukemia with V3-21 Gene Usage.

Dirk Kienle, Alexander Kröber, Dirk Winkler, Daniel Mertens, Annett Habermann, Peter Lichter, Hartmut Döhner, Stephan Stilgenbauer

Blood (2004) 104 (11): 773.

https://doi.org/10.1182/blood.V104.11.773.773

Published: 2004

Journal Articles

Correlation of Quantitative Gene Expression by RQ-PCR with Clinical and Biologic Factors in Mantle Cell Lymphoma.

Dirk Kienle, Doreen Saupe, Tiemo Katzenberger, Axel Benner, Elke Leupolt, Andreas Rosenwald, German Ott, Peter Lichter, Hartmut Döhner, Stephan Stilgenbauer

Blood (2004) 104 (11): 696.

https://doi.org/10.1182/blood.V104.11.696.696

Published: 2004

NARROW

CLL with Mutated IGHV4-34 Antigen Receptors Is Clinically Heterogeneous: Antigen Receptor Stereotypy Makes the Difference

Charting Unique Signatures of Somatic Hypermutation Amongst Chronic Lymphocytic Leukemia Patients Expressing IGHV4-34 Clonotypic B Cell Receptors

Telomere length in mantle cell lymphoma

Telomere Length in Mantle Cell Lymphoma.

miR-34a as part of the resistance network in chronic lymphocytic leukemia

Quantitative Gene Expression Analysis of Surrogate Markers for Genetic Risk Groups and Survival in CLL

Mir-34a as Part of the Chemotherapy Resistance Network in Chronic Lymphocytic Leukemia.

17p Deletion in CLL: Detailed Analysis of TP53 Mutations, Alternative Mechanisms of p53 Inactivation, Clone Size and Clonal Evolution

Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia

Clonal Evolution in Chronic Lymphocytic Leukemia: Acquisition of High-Risk Genomic Aberrations Associated with Unmutated VH, Resistance to Therapy, and Short Survival.

Array-CGH Based Genomic Profiling in B-Cell Chronic Lymphocytic Leukemia Reveals Specific Correlations of Genomic Imbalances and Prognostic Subgroups and Underlines the Consistency of Chromosomal Aberration Patterns within This Disease.

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in V H 3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status

Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes

17p Deletion Predicts for Inferior Overall Survival after Fludarabine - Based First Line Therapy in Chronic Lymphocytic Leukemia: First Analysis of Genetics in the CLL4 Trial of the GCLLSG.

The Paternally Expressed Gene 10 (PEG10) on Chromosome 7q21 Is Overexpressed and Imprinted in High-Risk B-CLL.

Strikingly Homologous Immunoglobulin Gene Rearrangements and Poor Outcome in V H 3-21-Utilizing Chronic Lymphocytic Leukemia Independent of Geographical Origin and Mutational Status.

Subcutaneous Campath-1H (Alemtuzumab) in Fludarabine-Refractory Cll: Interim Analysis of the CLL2h Study of the German Cll Study Group (GCLLSG).

ZAP-70 Expression, VH-Mutation Status, Genomic Aberrations and Prognosis in Chronic Lymphocytic Leukemia.

High ZAP-70 and Differential Expression of B-Cell Receptor Related Genes in Chronic Lymphocytic Leukemia with V3-21 Gene Usage.

Correlation of Quantitative Gene Expression by RQ-PCR with Clinical and Biologic Factors in Mantle Cell Lymphoma.

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American Society of Hematology

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American Society of Hematology

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