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Tina Denzel
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Journal Articles

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial

Clinical Trials & Observations
Thorsten Zenz, Sonja Häbe, Tina Denzel, Julia Mohr, Dirk Winkler, Andreas Bühler, Antonio Sarno, Silja Groner, Daniel Mertens, Raymonde Busch, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2009) 114 (13): 2589–2597.
https://doi.org/10.1182/blood-2009-05-224071
Published: 2009
Includes: Supplemental data
Journal Articles

TP53 Abnormalities in Chronic Lymphocytic Leukemia Exhibit a Disease Specific Profile: Meta-Analysis of 270 Mutations.

Thorsten Zenz, Jana Smadova, Dominik Vollmer, Martin Trbusek, Axel Benner, Sonja Häbe, Tina Denzel, Jitka Malcikova, Sim Truong, Nancy Patten, David Oscier, Rachel Ibbotson, Anne Gardiner, Ian Tracy, Ke Lin, Andrew Pettitt, Sarka Popsilova, Jiri Mayer, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2008) 112 (11): 2077.
https://doi.org/10.1182/blood.V112.11.2077.2077
Published: 2008
Journal Articles

17p Deletion in CLL: Detailed Analysis of TP53 Mutations, Alternative Mechanisms of p53 Inactivation, Clone Size and Clonal Evolution

Thorsten Zenz, Antonio Sarno, Sonja Häbe, Tina Denzel, Julia Mohr, Dominik Vollmer, Maria Heuberger, Dirk Winkler, Dirk Kienle, Andreas Bühler, Sim Truong, Nancy Patten, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2008) 112 (11): 782.
https://doi.org/10.1182/blood.V112.11.782.782
Published: 2008
Journal Articles

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

Thorsten Zenz, Alexander Kröber, Katrin Scherer, Sonja Häbe, Andreas Bühler, Axel Benner, Tina Denzel, Dirk Winkler, Jennifer Edelmann, Carsten Schwänen, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2008) 112 (8): 3322–3329.
https://doi.org/10.1182/blood-2008-04-154070
Published: 2008
Journal Articles

p53 Inactivation in CLL: Pattern of 110 TP53 Mutations.

Thorsten Zenz, MD, Martin Trbusek, PhD, Jana Smardova, PhD, Sonja Häbe, Tina Denzel, Jitka Malcikova, Michael Doubek, PhD, Jiri Schwarz, MD, Hartmut Dohner, MD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2007) 110 (11): 2064.
https://doi.org/10.1182/blood.V110.11.2064.2064
Published: 2007
Journal Articles

Influence of MDM2 Single Nucleotide Polymorphism SNP309 on Disease Onset and Course in CLL.

Thorsten Zenz, MD, Sonja Häbe, Andreas Bühler, MD, Alexander Kröber, MD, Tina Denzel, Hartmut Döhner, MD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2006) 108 (11): 4938.
https://doi.org/10.1182/blood.V108.11.4938.4938
Published: 2006