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Journal Articles

Cancer Pathway Connectivity Resolved By Drug Perturbation and RNA Sequencing

Thi Huong Lan Do, Caroline Lohoff, Ferris Jung, Sandra Kummer, Vladimir Benes, Wolfgang Huber, Junyan Lu, Thorsten Zenz

Blood (2024) 144 (Supplement 1): 3584.

https://doi.org/10.1182/blood-2024-201366

Published: 2024

Journal Articles

Unraveling Molecular Subgroup-Specific Pathway Dependencies in Chronic Lymphocytic Leukemia through Drug-Perturbed Transcriptomic Profiling and Statistical Modeling

Caroline Lohoff, Thi Huong Lan Do, Ferris Jung, Sandra Kummer, Vladimir Benes, Wolfgang Huber, Thorsten Zenz, Junyan Lu

Blood (2024) 144 (Supplement 1): 276.

https://doi.org/10.1182/blood-2024-210844

Published: 2024

Journal Articles

Durability of Complete Responses in Patients from the ECHELON-3 Study

Blood (2024) 144 (Supplement 1): 3101.

https://doi.org/10.1182/blood-2024-194158

Published: 2024

Journal Articles

Dissecting the Single Cell Landscape of Leukemic Mantle Cell Lymphoma

Tobias Wertheimer, Hosna Baniadam, Stefanie Reisenauer, Marcel Pohly, Lukas Rindlisbacher, Minqi Lin, Stefanie Kreutmair, Susanne Unger, Jarno Kivioja, Andreas Moor, Burkhard Becher, Wolfgang Huber, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 180.

https://doi.org/10.1182/blood-2023-185576

Published: 2023

Journal Articles

The Gene Expression Landscape of BTK Inhibitor Treatment in Chronic Lymphocytic Leukemia Exposed By Shallow Depth RNA Sequencing

Thi Huong Lan Do, Caroline Lohoff, Ferris Jung, Vladimir Benes, Wolfgang Huber, Junyan Lu, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 4633.

https://doi.org/10.1182/blood-2023-178562

Published: 2023

Journal Articles

Deciphering the Dynamics of the B-NHL Single-Cell Landscape during BTK Inhibition

Hosna Baniadam, Tobias Wertheimer, Stefanie Reisenauer, Odit Gutwein, Thi Huong Lan Do, Marcel Pohly, Ester Cannizzaro, Lukas Rindlisbacher, Stefanie Kreutmair, Susanne Unger, Can Ulutekin, Marijne Vermeer, Colin Sparano, Andreas Moor, Wolfgang Huber, Burkhard Becher, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 3007.

https://doi.org/10.1182/blood-2023-189735

Published: 2023

Journal Articles

DNA Methylation-Based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma

Blood (2023) 142 (Supplement 1): 174.

https://doi.org/10.1182/blood-2023-189835

Published: 2023

Journal Articles

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Lisa Brandmeier, Veronika Ecker, Martina Stumpf, Piero Giansanti, Aida Varela Moreira, Lisa Pfeuffer, Marcel Fens, Junyan Lu, Bernhard Küster, Thomas Engleitner, Simon Heidegger, Ingo Ringshausen, Thorsten Zenz, Clemens-Martin Wendtner, Markus Müschen, Jürgen Ruland, Maike Buchner

Blood (2022) 140 (Supplement 1): 9840–9841.

https://doi.org/10.1182/blood-2022-160103

Published: 2022

Journal Articles

Functional Anti-Apoptotic Protein Dependence and Its Relation to Genomic Prognostic Markers and Response to Treatment in Chronic Lymphocytic Leukemia

Stephen Jun Fei Chong, Junyan Lu, Rebecca Valentin, Timothy Z. Lehmberg, Mary C Collins, Charles Herbaux, Carsten Utoft Niemann, Wolfgang Huber, Thorsten Zenz, Matthew S. Davids

Blood (2022) 140 (Supplement 1): 4119–4120.

https://doi.org/10.1182/blood-2022-165936

Published: 2022

Journal Articles

Development of a Novel Chromatin Activation Score As a Powerful Independent Prognostic Factor in Chronic Lymphocytic Leukemia

Vicente Chapaprieta, Alba Maiques-Diaz, Guillem Clot, Ferran Nadeu, Judith Mateos-Jaimez, Anna Vidal, Stella Charalampopoulou, Martí Duran-Ferrer, Romina Royo, Junyan Lu, Thorsten Zenz, Julio Delgado, Armando Lopez-Guillermo, Elías Campo, José I. Martín-Subero

Blood (2022) 140 (Supplement 1): 4123–4124.

https://doi.org/10.1182/blood-2022-158919

Published: 2022

Journal Articles

A Comprehensive DNA Methylome Analysis of Stereotyped and Non-Stereotyped CLL Reveals an Epigenetic Signature with Strong Clinical Impact Encompassing IGHV Status, Stereotypes and IGLV3-21 R110

Blood (2022) 140 (Supplement 1): 1800–1802.

https://doi.org/10.1182/blood-2022-165181

Published: 2022

Journal Articles

CAR T Cells and Their Immune Environment Synergize to Shape Distinct Immune Profiles in Response Versus Toxicity in B Cell Lymphoma Patients

Stefanie Kreutmair, Maximilian M Schaefer, Sebastian Stolz, Carla Merten, Can Ulutekin, Florian Ingelfinger, Susanne Unger, Chiara Alberti, Tobias Wertheimer, Aakriti Sethi, Thorsten Zenz, Markus G Manz, Antonia Maria Susanne Müller, Corinne C Widmer, Burkhard Becher

Blood (2022) 140 (Supplement 1): 7504–7505.

https://doi.org/10.1182/blood-2022-168905

Published: 2022

Journal Articles

Genetic and phenotypic attributes of splenic marginal zone lymphoma

Ferdinando Bonfiglio, Alessio Bruscaggin, Francesca Guidetti, Lodovico Terzi di Bergamo, Martin Faderl, Valeria Spina, Adalgisa Condoluci, Luisella Bonomini, Gabriela Forestieri, Ricardo Koch, Deborah Piffaretti, Katia Pini, Maria Cristina Pirosa, Micol Giulia Cittone, Alberto Arribas, Marco Lucioni, Guido Ghilardi, Wei Wu, Luca Arcaini, Maria Joao Baptista, Gabriela Bastidas, Silvia Bea, Renzo Boldorini, Alessandro Broccoli, Marco Matteo Buehler, Vincenzo Canzonieri, Luciano Cascione, Luca Ceriani, Sergio Cogliatti, Paolo Corradini, Enrico Derenzini, Liliana Devizzi, Sascha Dietrich, Angela Rita Elia, Fabio Facchetti, Gianluca Gaidano, Juan Fernando Garcia, Bernhard Gerber, Paolo Ghia, Maria Gomes da Silva, Giuseppe Gritti, Anna Guidetti, Felicitas Hitz, Giorgio Inghirami, Marco Ladetto, Armando Lopez-Guillermo, Elisa Lucchini, Antonino Maiorana, Roberto Marasca, Estella Matutes, Veronique Meignin, Michele Merli, Alden Moccia, Manuela Mollejo, Carlos Montalban, Urban Novak, David Graham Oscier, Francesco Passamonti, Francesco Piazza, Stefano Pizzolitto, Alessandro Rambaldi, Elena Sabattini, Gilles Salles, Elisa Santambrogio, Lydia Scarfò, Anastasios Stathis, Georg Stüssi, Julia T. Geyer, Gustavo Tapia, Corrado Tarella, Catherine Thieblemont, Thomas Tousseyn, Alessandra Tucci, Giorgio Vanini, Carlo Visco, Umberto Vitolo, Renata Walewska, Francesco Zaja, Thorsten Zenz, Pier Luigi Zinzani, Hossein Khiabanian, Arianna Calcinotto, Francesco Bertoni, Govind Bhagat, Elias Campo, Laurence De Leval, Stefan Dirnhofer, Stefano A. Pileri, Miguel A. Piris, Alexandra Traverse-Glehen, Alexander Tzankov, Marco Paulli, Maurilio Ponzoni, Luca Mazzucchelli, Franco Cavalli, Emanuele Zucca, Davide Rossi

Blood (2022) 139 (5): 732–747.

https://doi.org/10.1182/blood.2021012386

Published: 2022

Includes: Supplemental data

Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Blood (2022) 139 (4): 538–553.

https://doi.org/10.1182/blood.2021012081

Published: 2022

Includes: Supplemental data

Journal Articles

The protein landscape of chronic lymphocytic leukemia

Blood (2021) 138 (24): 2514–2525.

https://doi.org/10.1182/blood.2020009741

Published: 2021

Includes: Supplemental data

Journal Articles

Different Prognostic Impact of Recurrent Gene Mutations in IGHV-Mutated and IGHV-Unmutated Chronic Lymphocytic Leukemia: A Retrospective, Multi-Center Cohort Study By Eric, the European Research Initiative on CLL, in Harmony

Larry Mansouri, Birna Thorvaldsdottir, Lesley-Ann Sutton, Manja Meggendorfer, Ferran Nadeu, Christian Brieghel, Helen Parker, Stamatia Laidou, Riccardo Moia, Davide Rossi, Mark Catherwood, Jana Kotaskova, Julio Delgado, Ana E Rodríguez-Vicente, Rocio Benito, Gian Matteo Rigolin, Silvia Bonfiglio, Lydia Scarfo, Mattias Mattsson, Zadie Davis, Ajay Gogia, Lata Rani, Panagiotis Baliakas, Cecilia Jylhä, Aron Skaftason, Inmaculada Rapado, Fatima Miras, Joaquin Martinez-Lopez, Javier de la Serna, Jesús M Hernández Rivas, Patrick Thornton, Maria Jose Larrayoz, María José Calasanz, Zoltán Mátrai, Csaba Bodor, Karin E. Smedby, Blanca Espinet, Anna Puiggros, Ritu Gupta, Lars Bullinger, Francesc Bosch, Bárbara Tazón, Fanny Baran-Marszak, David Oscier, Florence Nguyen-Khac, Thorsten Zenz, María José Terol, Antonio Cuneo, María Hernández-Sánchez, Sarka Pospisilova, Ken I Mills, Gianluca Gaidano, Carsten Utoft Niemann, Elías Campo, Jonathan C Strefford, Paolo Ghia, Kostas Stamatopoulos, Richard Rosenquist

Blood (2021) 138 (Supplement 1): 2617.

https://doi.org/10.1182/blood-2021-150648

Published: 2021

Journal Articles

IGLV3-21 R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics

Ferran Nadeu, Romina Royo, Guillem Clot, Martí Duran-Ferrer, Alba Navarro, Silvia Martín, Junyan Lu, Thorsten Zenz, Tycho Baumann, Pedro Jares, Xose S. Puente, José I. Martín-Subero, Julio Delgado, Elías Campo

Blood (2021) 137 (21): 2935–2946.

https://doi.org/10.1182/blood.2020008311

Published: 2021

Includes: Supplemental data

Journal Articles

The IGLV3-21 R110 Defines a Subset of Chronic Lymphocytic Leukemia with Intermediate Epigenetic Subtype and Poor Outcome

Ferran Nadeu, Romina Royo, Guillem Clot, Martí Duran-Ferrer, Alba Navarro, PhD, Silvia Martín, Junyan Lu, Thorsten Zenz, Tycho Baumann, Pedro Jares, Xose S Puente, PhD, Jose Ignacio Martin-Subero, Julio Delgado, MD PhD, Elias Campo, MDPhD

Blood (2020) 136 (Supplement 1): 43–44.

https://doi.org/10.1182/blood-2020-134786

Published: 2020

Journal Articles

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-137528

Published: 2020

Journal Articles

Identification of 2 DNA methylation subtypes of Waldenström macroglobulinemia with plasma and memory B-cell features

Damien Roos-Weil, Brian Giacopelli, Marine Armand, Véronique Della-Valle, Hussein Ghamlouch, Camille Decaudin, Marlen Metzner, Junyan Lu, Magali Le Garff-Tavernier, Véronique Leblond, Paresh Vyas, Thorsten Zenz, Florence Nguyen-Khac, Olivier A. Bernard, Christopher C. Oakes

Blood (2020) 136 (5): 585–595.

https://doi.org/10.1182/blood.2020005081

Published: 2020

Includes: Supplemental data

NARROW

Cancer Pathway Connectivity Resolved By Drug Perturbation and RNA Sequencing

Unraveling Molecular Subgroup-Specific Pathway Dependencies in Chronic Lymphocytic Leukemia through Drug-Perturbed Transcriptomic Profiling and Statistical Modeling

Durability of Complete Responses in Patients from the ECHELON-3 Study

Dissecting the Single Cell Landscape of Leukemic Mantle Cell Lymphoma

The Gene Expression Landscape of BTK Inhibitor Treatment in Chronic Lymphocytic Leukemia Exposed By Shallow Depth RNA Sequencing

Deciphering the Dynamics of the B-NHL Single-Cell Landscape during BTK Inhibition

DNA Methylation-Based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma

Negative Feedback Regulation of MAPK Signaling Is an Important Driver of CLL Progression

Functional Anti-Apoptotic Protein Dependence and Its Relation to Genomic Prognostic Markers and Response to Treatment in Chronic Lymphocytic Leukemia

Development of a Novel Chromatin Activation Score As a Powerful Independent Prognostic Factor in Chronic Lymphocytic Leukemia

A Comprehensive DNA Methylome Analysis of Stereotyped and Non-Stereotyped CLL Reveals an Epigenetic Signature with Strong Clinical Impact Encompassing IGHV Status, Stereotypes and IGLV3-21 R110

CAR T Cells and Their Immune Environment Synergize to Shape Distinct Immune Profiles in Response Versus Toxicity in B Cell Lymphoma Patients

Genetic and phenotypic attributes of splenic marginal zone lymphoma

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

The protein landscape of chronic lymphocytic leukemia

Different Prognostic Impact of Recurrent Gene Mutations in IGHV-Mutated and IGHV-Unmutated Chronic Lymphocytic Leukemia: A Retrospective, Multi-Center Cohort Study By Eric, the European Research Initiative on CLL, in Harmony

IGLV3-21 R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics

The IGLV3-21 R110 Defines a Subset of Chronic Lymphocytic Leukemia with Intermediate Epigenetic Subtype and Poor Outcome

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Identification of 2 DNA methylation subtypes of Waldenström macroglobulinemia with plasma and memory B-cell features

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American Society of Hematology

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American Society of Hematology

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