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Louis M. Staudt
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Journal Articles

A Phase 2 Response-Adapted Study of Daratumumab, Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple Myeloma

Roshani Patel, Amrit Bhaskarla, Max J Gordon, Michael Emanuel, Dana I. Delgado Colon, Hao-Wei Wang, Constance M. Yuan, Liza Lindenberg, Esther Mena, Baris Turkbey, Nick Micheletti, Laura M Yee, Nisha Patel, Irina Maric, Raul C. Braylan, Katherine R. Calvo, Louis M. Staudt, Ryan M. Young, Mark Roschewski, Dickran Kazandjian, Elizabeth Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 7059.
https://doi.org/10.1182/blood-2024-201563
Published: 2024
Journal Articles

A Pilot Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (VIPOR) for Diffuse Large B-Cell Lymphoma Involving the Central Nervous System

Disha Dalela, Rahul Lakhotia, Christopher Melani, Stefania Pittaluga, James D. Phelan, Jagan R. Muppidi, Sarah Evans, Amynah Pradhan, Atekelt Tadese, Candis Morrison, Seth M. Steinberg, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1724.
https://doi.org/10.1182/blood-2024-194482
Published: 2024
Journal Articles

Phase 1/2 Study of Polatuzumab in Combination with Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR-P) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Preliminary Safety, Efficacy, and Molecular Analysis

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D. Phelan, Jagan R. Muppidi, Max J Gordon, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Da Wei Huang, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Anna M Juanitez, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Allison P. Jacob, Heidi Simmons, Seth M. Steinberg, Elaine S. Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1722.
https://doi.org/10.1182/blood-2024-197987
Published: 2024
Journal Articles

An Llmpp Study: Genomic Characterization of Novel PTCL- Biological Subtypes Reveal Distinctive Therapeutic Vulnerabilities

Dylan T. Jochum, Alyssa Bouska, Sunandini Sharma, Suchita Vishwakarma, Catalina Amador, Waseem Gul Lone, Ab Rauf Shah, Abdul Rouf Mir, Mahfuza Afroz Soma, Syed Mohsin Mehmood, Zaina Nasser, Andrew L. Feldman, Timothy C. Greiner, Julie M. Vose, James R. Cook, Sarah L. Ondrejka, Elaine S. Jaffe, Andreas Rosenwald, German Ott, Phillipp W. Raess, Kerry J. Savage, Graham W. Slack, David W. Scott, Joo Y Song, Elias Campo, Louis M. Staudt, Lisa M. Rimsza, Dennis D Weisenburger, Giorgio Inghirami, Amar Natarajan, Javeed Iqbal, Wing Chung Chan
Journal: Blood
Blood (2024) 144 (Supplement 1): 456.
https://doi.org/10.1182/blood-2024-209396
Published: 2024
Journal Articles

Romidepsin, Azacitidine, Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-Cell Lymphoma

Max J Gordon, Milos D Miljkovic, Samuel Ng, Rahul Lakhotia, Christopher Melani, Kevin Conlon, James D. Phelan, Bonita Bryant, Laura M Yee, Stefania Pittaluga, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 984.
https://doi.org/10.1182/blood-2024-199196
Published: 2024
Journal Articles

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Andrew L. Feldman, Guangzhen Hu, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Jimena B. Gimenez, Farah M. Salama, Min Shi, Elías Campo, Wing Chung Chan, James R. Cook, Giorgio Inghirami, Elaine S. Jaffe, Ryan Morin, Phillipp W. Raess, Andreas Rosenwald, Kerry J. Savage, Louis M. Staudt, George W. Wright, Catalina Amador, Jan Delabie, Timothy C. Greiner, Javeed Iqbal, Laura K. Hilton, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Graham W. Slack, Susan L. Slager, Joo Y. Song, Hao-Wei Wang, Ahmed A. Aljudi, Stephen M. Ansell, Carlos Barrionuevo, James R. Cerhan, Jennifer R. Chapman-Fredricks, Weina Chen, Laurence de Leval, Alejandro A. Gru, David L. Jaye, Liuyan Jiang, Brad S. Kahl, Kennosuke Karube, Young Hyeh Ko, Eric Mou, Matthew J. Maurer, L. Jeffrey Medeiros, Roberto N. Miranda, Naoki Oishi, Perry M. Anamarija, Akira Satou, Xueju Wang, Ryan A. Wilcox, Xiaojun Wu, Tadashi Yoshino, Yu Zeng
Journal: Blood
Blood (2024) 144 (Supplement 1): 2974.
https://doi.org/10.1182/blood-2024-202410
Published: 2024
Journal Articles

Phase 1 Study of Escalating Doses of Ibrutinib in Teddi-R with Isavuconazole for Relapsed and Refractory Primary DLBCL of the CNS

Mark Roschewski, Christopher Melani, Rahul Lakhotia, Tatyana Gavrilova, Jagan R. Muppidi, James D. Phelan, Michail S. Lionakis, Kieron Dunleavy, Lode J. Swinnen, Matthias Holdhoff, Catherine E. Lai, Sami Ibrahimi, Michael Glantz, Jan Drappatz, John A. Butman, Stefania Pittaluga, Kim Johnson, Candis Morrison, Nick Micheletti, John D. Heiss, William D. Figg, Elaine S. Jaffe, S. Percy Ivy, Richard Little, Louis M. Staudt, Wyndham H. Wilson
Journal: Blood
Blood (2024) 144 (Supplement 1): 3122.
https://doi.org/10.1182/blood-2024-199168
Published: 2024
Journal Articles

Circulating Tumor DNA Predicts Time to First Treatment in Previously Untreated Follicular Lymphoma: Analysis from a Prospective Clonal Evolution Study

Rahul Lakhotia, Stefania Pittaluga, James D. Phelan, Allison Graeter, Christopher Melani, Max J Gordon, Jagan R. Muppidi, Sam Y. Ng, Sumaya Berg, Sarah Evans, Amynah Pradhan, Atekelt Tadese, Candis Morrison, Bonita Bryant, Yandan Yang, Theresa Davies-Hill, Liza Lindenberg, Mark Ahlman, Esther Mena, Ethan Bergvall, Nick Micheletti, Laura M Yee, Allison P. Jacob, Monica Gallucci, Heidi Simmons, Alexander Bagaev, Mark Meerson, Ekaterina Postovalova, Olga Kudryashova, Nikita Kotlov, Nathan H. Fowler, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 2958.
https://doi.org/10.1182/blood-2024-201711
Published: 2024
Journal Articles

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Julius C. Enssle, Björn Häupl, Arber Qoku, Boya Wang, George W. Wright, Sharon Barrans, Matthew Anthony Care, Cathy Burton, Caitlin Gribbin, Sebastian Scheich, Sebastian Wolf, James D. Phelan, Da Wei Huang, Andrea diFonzo, Martine Pape, Marion Bodach, Dominique Jahn, Uwe Plessmann, Daniel J Hodson, Bernhard Kuster, Roland Schmitz, Henning Urlaub, Reuben Tooze, Giorgio Inghirami, Florian Buettner, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2024) 144 (Supplement 1): 229.
https://doi.org/10.1182/blood-2024-204606
Published: 2024
Journal Articles

Phase 1b/2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR) in Relapsed/Refractory and Treatment-Naïve Mantle Cell Lymphoma: Preliminary Analysis of Safety, Efficacy, and Minimal Residual Disease

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D. Phelan, Jagan R. Muppidi, Max J Gordon, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Da Wei Huang, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Anna M Juanitez, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Colleen Ramsower, Lisa M. Rimsza, Allison P. Jacob, Heidi Simmons, Seth M. Steinberg, Elaine S. Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2024) 144 (Supplement 1): 750.
https://doi.org/10.1182/blood-2024-197956
Published: 2024
Journal Articles

Genetic Subclones Reveal Phenotypic Heterogeneity in Diffuse Large B-Cell Lymphoma

Boya Wang, George W. Wright, Julius C. Enssle, Yandan Yang, Da Wei Huang, Xin Yu, Arvin E Ruiz, James D. Phelan, Arthur L Shaffer, III, Thomas Oellerich, Giorgio Inghirami, Louis M. Staudt
Journal: Blood
Blood (2024) 144 (Supplement 1): 451.
https://doi.org/10.1182/blood-2024-204201
Published: 2024
Journal Articles

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

Laura K. Hilton, Brett Collinge, Susana Ben-Neriah, Waleed Alduaij, Haya Shaalan, Andrew P. Weng, Manuela Cruz, Graham W. Slack, Pedro Farinha, Tomoko Miyata-Takata, Merrill Boyle, Barbara Meissner, James R. Cook, Sarah L. Ondrejka, German Ott, Andreas Rosenwald, Elias Campo, Catalina Amador, Timothy C. Greiner, Philipp W. Raess, Joo Y. Song, Giorgio Inghirami, Elaine S. Jaffe, Dennis D. Weisenburger, Wing C. Chan, Klaus Beiske, Kai Fu, Jan Delabie, Stefania Pittaluga, Javeed Iqbal, George Wright, Laurie H. Sehn, Kerry J. Savage, Andrew J. Mungall, Andrew L. Feldman, Louis M. Staudt, Christian Steidl, Lisa M. Rimsza, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2024) 144 (5): 525–540.
https://doi.org/10.1182/blood.2024024251
Published: 2024
Includes: Supplemental data
Journal Articles

Phase Ib/II Study of Multi-Targeted Therapy with Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR) in Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D Phelan, Da Wei Huang, George Wright, Jillian Simard, Jagan R. Muppidi, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Svetlana Pack, Cody J Peer, Oluwatobi Arisa, Esther Mena, Maria L. Lindenberg, Ethan Bergvall, Craig A. Portell, Rafic J Farah, Seung Tae Lee, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Anna M Juanitez, Crystal Lu, Allison P. Jacob, Heidi Simmons, William D Figg, Seth M. Steinberg, Elaine S Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2023) 142 (Supplement 1): 434.
https://doi.org/10.1182/blood-2023-180173
Published: 2023
Journal Articles

Inhibition of NOTCH4 Sensitizes FLT3/ITD Acute Myeloid Leukemia Cells to FLT3 Tyrosine Kinase Inhibition

Ruiqi Zhu, Courtney Shirley, Haihua Chu, Li Li, Bao Nguyen, Jaesung Seo, Tessa Seale, Amy Duffield, Louis M. Staudt, Mark J. Levis, Yu Hu, Donald Small
Journal: Blood
Blood (2023) 142 (Supplement 1): 5769.
https://doi.org/10.1182/blood-2023-190696
Published: 2023
Journal Articles

Preliminary Analysis of an Ongoing Phase II Study of Response-Adapted Therapy with Copanlisib and Rituximab for Untreated Follicular Lymphoma

Rahul Lakhotia, Christopher Melani, Jagan R. Muppidi, Stefania Pittaluga, James D Phelan, Colleen Ramsower, Lisa M. Rimsza, Ryan S Robertorye, George Wright, Mark Meerson, Ekaterina Postovalova, Alexander Bagaev, Nathan Fowler, Liza Lindenberg, Esther Mena, Ethan Bergvall, Amynah Pradhan, Atekelt Tadese, Candis Morrison, Sarah Evans, Sumaya Berg, Seth M. Steinberg, William Figg, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 1676.
https://doi.org/10.1182/blood-2023-185038
Published: 2023
Journal Articles

Phase I Study of Response-Adapted Treatment with Venetoclax, Obinutuzumab, and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-Cell Malignancies

Rahul Lakhotia, Christopher Melani, Stefania Pittaluga, James D Phelan, Amynah Pradhan, Atekelt Tadese, Candis Morrison, Sarah Evans, Seth M. Steinberg, William Figg, Elaine S Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 6172.
https://doi.org/10.1182/blood-2023-178766
Published: 2023
Journal Articles

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Catalina Amador, Elias Campo, Wing C. Chan, James R. Cook, Jan Delabie, Pedro Farinha, Kai Fu, Timothy C. Greiner, Giorgio Inghirami, Javeed Iqbal, Elaine S. Jaffe, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Phil Raess, Andreas Rosenwald, Kerry J. Savage, Graham Slack, Susan L. Slager, Joo Y. Song, Louis M. Staudt, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A. Wilcox, Xueju Wang, Akira Satou, Anamarija M. Perry, Roberto Miranda, L. Jeffrey Medeiros, Matthew J. Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S. Kahl, Liuyan Jiang, David L Jaye, Laurence de Leval, Weina Chen, Jennifer R. Chapman-Fredricks, James R. Cerhan, Carlos Barrionuevo, Stephen M Ansell, Ahmed Aljudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 847.
https://doi.org/10.1182/blood-2023-186969
Published: 2023
Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Phase 2 Response-Adapted Study of Ibrutinib with Temozolomide, Etoposide, Liposomal Doxorubicin, Dexamethasone, and Rituximab (TEDDI-R) for Secondary CNS Lymphoma

Jillian Simard, James D Phelan, Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, Jagan R. Muppidi, Michail Lionakis, Cody J Peer, Amynah Pradhan, Matthias Holdhoff, Lode J. Swinnen, Kieron Dunleavy, Catherine Lai, Sami Ibrahimi, Michael Glantz, John A Butman, Kim Johnson, Seth M. Steinberg, William Figg, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 854.
https://doi.org/10.1182/blood-2023-177994
Published: 2023
Journal Articles

Molecular Determinants of Sensitivity to Polatuzumab-Vedotin in Diffuse Large B-Cell Lymphoma

Sean R Corcoran, Jaewoo Choi, Rachel E Fenner, Xin Yu, Sebastian Scheich, Tony Hsiao, Galina Schevchenko, Vivian M Morris, James D Phelan, Evangelia K Papachristou, Kamal Kishore, Clive S D'Santos, Yanlong Ji, Stefania Pittaluga, George Wright, Henning Urlaub, Kuan-Ting Pan, Thomas Oellerich, Jagan R. Muppidi, Daniel James Hodson, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2819.
https://doi.org/10.1182/blood-2023-178059
Published: 2023