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Journal Articles

Hematopoietic Differentiation from Single Codon Perspective

Marius Külp, Adrien Jolly, Tessa Schmachtel, Björn Häupl, Thomas Oellerich, Halvard Bonig, Michael A. Rieger
Journal: Blood
Blood (2024) 144 (Supplement 1): 433.
https://doi.org/10.1182/blood-2024-209604
Published: 2024
Journal Articles

Characterizing the Microbiome-Immune Axis in Hematopoietic Stem Cell Recipients

Sabrina A. Becker, Julius C. Enssle, Anne C. Wilke, Sylvia Pfundt, Nico Zeltner, Ana Jankovic, Sebastian Wolf, Thomas A. Wichelhaus, Volkard A. J. Kempf, Maria J. G. T. Vehreschild, Hubert Serve, Thomas Oellerich, Björn Steffen, Sebastian Scheich
Journal: Blood
Blood (2024) 144 (Supplement 1): 2022.
https://doi.org/10.1182/blood-2024-207279
Published: 2024
Journal Articles

Posttranslational Changes in Histone Modification Driven By USP48 Loss Increase Sensitivity to Hypomethylating Agents in Acute Myeloid Leukemia

Constanze Schneider, Gabriela Alexe, Ashleigh Meyer, Lucy A Merickel, Allen T Basanthakumar, Audrey Taillon, Silvi Salhotra, Yara Rodriguez, Björn Häupl, David E. Root, Thomas Oellerich, Kimberly Stegmaier
Journal: Blood
Blood (2024) 144 (Supplement 1): 205.
https://doi.org/10.1182/blood-2024-206333
Published: 2024
Journal Articles

The Transcriptional Activators p300/Crebbp Are Context-Dependent Functional Repressors of Interferon Genes, Offering Therapeutic Promise in AML

Markus Meyerhöfer, Viral Shah, Aarón Gallego-Crespo, Malte Andreas Behrendt, Yawen Zhou, Maria Saura-Pañella, Björn Häupl, Thomas Kindler, Matthias Theobald, Falk Butter, George S Vassiliou, Michael Kühn, Brian J P Huntly, Thomas Oellerich, Daniel Sasca
Journal: Blood
Blood (2024) 144 (Supplement 1): 152.
https://doi.org/10.1182/blood-2024-194781
Published: 2024
Journal Articles

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Julius C. Enssle, Björn Häupl, Arber Qoku, Boya Wang, George W. Wright, Sharon Barrans, Matthew Anthony Care, Cathy Burton, Caitlin Gribbin, Sebastian Scheich, Sebastian Wolf, James D. Phelan, Da Wei Huang, Andrea diFonzo, Martine Pape, Marion Bodach, Dominique Jahn, Uwe Plessmann, Daniel J Hodson, Bernhard Kuster, Roland Schmitz, Henning Urlaub, Reuben Tooze, Giorgio Inghirami, Florian Buettner, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2024) 144 (Supplement 1): 229.
https://doi.org/10.1182/blood-2024-204606
Published: 2024
Journal Articles

Genetic Subclones Reveal Phenotypic Heterogeneity in Diffuse Large B-Cell Lymphoma

Boya Wang, George W. Wright, Julius C. Enssle, Yandan Yang, Da Wei Huang, Xin Yu, Arvin E Ruiz, James D. Phelan, Arthur L Shaffer, III, Thomas Oellerich, Giorgio Inghirami, Louis M. Staudt
Journal: Blood
Blood (2024) 144 (Supplement 1): 451.
https://doi.org/10.1182/blood-2024-204201
Published: 2024
Journal Articles

Real-World Evidence of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, Lenalidomide with or without Polatuzumab (VIPOR(P)) for Relapsed/Refractory Large B-Cell Lymphoma

Rebecca Wurm-Kuczera, Khouloud Kouidri, Meng Wang, Salahedine Ali, Shashwat Sahay, David Winkler, Ann-Kristin Leskien, Samixa Pudasaini, Joseph Kauer, Isabelle Krämer, Marcel Teichert, Niklas Gebauer, Ulf Schnetzke, Thomas Weber, Lukas Peter Frenzel, Anna-Carina Hund, Evgenii Shumilov, Mirjeta Berisha, Jakob Daniel Rudzki, Christian W. Scholz, Dimitrios Mougiakakos, Georg Lenz, Gerald Wulf, Martin Schmidt-Hieber, Bastian von Tresckow, Peter Dreger, Martin Dreyling, Oliver Weigert, Naveed Ishaque, Ulrich Keller, Christiane Pott, Thomas Oellerich, Björn Chapuy
Journal: Blood
Blood (2024) 144 (Supplement 1): 6494.
https://doi.org/10.1182/blood-2024-200002
Published: 2024
Journal Articles

Incidence, Risk Factors, and Outcomes of Candida Bloodstream Infections in Hematological and Oncological Patients

Sebastian Wolf, Sarah Weber, Aaron Janetta, Friederike Klein, Julius C. Enssle, Michael Hogardt, Volkard A. J. Kempf, Johanna Kessel, Maria J. G. T. Vehreschild, Björn Steffen, Thomas Oellerich, Hubert Serve, Sebastian Scheich
Journal: Blood
Blood (2024) 144 (Supplement 1): 2866.
https://doi.org/10.1182/blood-2024-205960
Published: 2024
Journal Articles

Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia

Eloísa Felipe Fumero, Carolin Walter, Joris Maximillian Frenz, Franca Seifert, Vijay Alla, Thorben Hennig, Linus Angenendt, Wolfgang Hartmann, Sebastian Wolf, Hubert Serve, Thomas Oellerich, Georg Lenz, Carsten Müller-Tidow, Christoph Schliemann, Otmar Huber, Martin Dugas, Matthias Mann, Ashok Kumar Jayavelu, Jan-Henrik Mikesch, Maria Francisca Arteaga
Journal: Blood
Blood (2024) 143 (22): 2284–2299.
https://doi.org/10.1182/blood.2023021640
Published: 2024
Includes: Supplemental data
Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Molecular Determinants of Sensitivity to Polatuzumab-Vedotin in Diffuse Large B-Cell Lymphoma

Sean R Corcoran, Jaewoo Choi, Rachel E Fenner, Xin Yu, Sebastian Scheich, Tony Hsiao, Galina Schevchenko, Vivian M Morris, James D Phelan, Evangelia K Papachristou, Kamal Kishore, Clive S D'Santos, Yanlong Ji, Stefania Pittaluga, George Wright, Henning Urlaub, Kuan-Ting Pan, Thomas Oellerich, Jagan R. Muppidi, Daniel James Hodson, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2819.
https://doi.org/10.1182/blood-2023-178059
Published: 2023
Journal Articles

Molecular Mechanism of Action of Glucocorticoids in Lymphoma Therapy

Jaewoo Choi, Michele Ceribelli, James D Phelan, Björn Häupl, Da Wei Huang, George Wright, Tony Hsiao, Vivian M Morris, Francesco Ciccarese, Boya Wang, Sean R Corcoran, Sebastian Scheich, Xin Yu, Weihong Xu, Yandan Yang, Joyce Zhou, Grace Zhang, Jagan R. Muppidi, Giorgio Inghirami, Thomas Oellerich, Craig J. Thomas, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2986.
https://doi.org/10.1182/blood-2023-174325
Published: 2023
Journal Articles

Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies

Johannes Adrian Hildebrand, Sarah Haebe, Verena Passerini, Michael Heide, William Keay, Louisa Adolph, Lukas Ulrich, Natyra Tahiri, Raphael Koch, Jessica Duffy, Haley Martin, Liam Hackett, Jeremy Zhang, Christina Ludwig, Stefanie Wilhelm, Björn Häupl, Carmen Doebele, Michael von Bergwelt-Baildon, Axel Lechner, Tobias Herold, Christian Kellner, Martina Rudelius, Thomas Oellerich, Marc Schmidt-Supprian, Abner Louissaint, Matthew S Davids, Oliver Weigert
Journal: Blood
Blood (2023) 142 (Supplement 1): 4358.
https://doi.org/10.1182/blood-2023-174384
Published: 2023
Journal Articles

Immune Responses after One Versus Two Influenza A/B Vaccinations in Patients with Multiple Myeloma

Julius Enssle, Tonio Brinkschmidt, Ralf Dürrwald, Sebastian Wolf, David Zurmeyer, Björn Steffen, Evelyn Ullrich, Hubert Serve, Thomas Oellerich, Ivana von Metzler
Journal: Blood
Blood (2023) 142 (Supplement 1): 4737.
https://doi.org/10.1182/blood-2023-180096
Published: 2023
Journal Articles

Alternative Splicing of Bcap (PIK3AP1) Enhances Oncogenic Signaling in Subsets of Activated B-Cell Diffuse Large B-Cell Lymphoma

Andy Itsara, Sebastian Scheich, Björn Häupl, Xin Yu, Thomas Oellerich, Louis M. Staudt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6394–6395.
https://doi.org/10.1182/blood-2022-163619
Published: 2022
Journal Articles

Analysis of Patient-Level Data from 3 Cooperative Group Trials Confirms a Survival Advantage for NPM1 m Patients Achieving MRD-Negative CR after Intensive Induction

Konstanze Döhner, Hartmut Döhner, Daniela Weber, Silke Kapp-Schwoerer, Amanda Gilkes, Ian Thomas, Sean Johnson, Nicola Potter, Yana Bevan, Jad Othman, Nigel H. Russell, Christoph Röllig, Christian Thiede, Martin Bornhaeuser, Thomas Oellerich, Jenna Elder, Luis A. Carvajal, Zung To, Jorge DiMartino, Richard Dillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 6293–6294.
https://doi.org/10.1182/blood-2022-159212
Published: 2022
Journal Articles

Breaking the Pump: Targeting the Sodium-Potassium Pump As a Therapeutic Strategy in Acute Myeloid Leukemia

Constanze Schneider, Hermes Spaink, Gabriela Alexe, Neekesh V. Dharia, Ashleigh Meyer, Delan Khalid, Sebastian Scheich, Björn Häupl, Louis M. Staudt, Thomas Oellerich, Kimberly Stegmaier
Journal: Blood
Blood (2022) 140 (Supplement 1): 4936–4937.
https://doi.org/10.1182/blood-2022-168226
Published: 2022
Journal Articles

Proteomic Characterization of Acute Myeloid Leukemia

Sebastian Wolf, Ashok Kumar Jayavelu, Florian Buettner, Gabriela Alexe, Björn Häupl, Constanze Schneider, Anne C Wilke, Alena Zindel, Dominique Jahn, Bianca Splettstoesser, Julius Christoph Enssle, Anjali Cremer, Christoph Röllig, Christian Thiede, Björn Steffen, Martin Bornhäuser, Henning Urlaub, Kimberly Stegmaier, Hubert Serve, Matthias Mann, Thomas Oellerich
Journal: Blood
Blood (2022) 140 (Supplement 1): 3456–3457.
https://doi.org/10.1182/blood-2022-169242
Published: 2022
Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Anne C. Wilke, Carmen Doebele, Alena Zindel, Kwang Seok Lee, Sara A. Rieke, Michele Ceribelli, Federico Comoglio, James D. Phelan, James Q. Wang, Yana Pikman, Dominique Jahn, Björn Häupl, Constanze Schneider, Sebastian Scheich, Frances A. Tosto, Hanibal Bohnenberger, Philipp Stauder, Frank Schnütgen, Mikolaj Slabicki, Zana A. Coulibaly, Sebastian Wolf, Kamil Bojarczuk, Björn Chapuy, Christian H. Brandts, Philipp Stroebel, Caroline A. Lewis, Michael Engelke, Xincheng Xu, Hahn Kim, Thanh Hung Dang, Roland Schmitz, Daniel J. Hodson, Kimberly Stegmaier, Henning Urlaub, Hubert Serve, Clemens A. Schmitt, Fernando Kreuz, Gero Knittel, Joshua D. Rabinowitz, Hans Christian Reinhardt, Matthew G. Vander Heiden, Craig Thomas, Louis M. Staudt, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2022) 139 (4): 538–553.
https://doi.org/10.1182/blood.2021012081
Published: 2022
Includes: Supplemental data
Journal Articles

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Entospletinib in Combination with Intensive Induction and Consolidation Chemotherapy in Adults with Newly Diagnosed N ucleophosmin 1- mutated Acute Myeloid Leukemia

John C. Byrd, Jorge E. Cortes, Mark D. Minden, Thomas Oellerich, Eytan M. Stein, Jenna Elder, Pavan Kumar, Gordon Bray, Jorge DiMartino, Wendy Stock
Journal: Blood
Blood (2021) 138 (Supplement 1): 1282.
https://doi.org/10.1182/blood-2021-145773
Published: 2021