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Axel Lechner
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Journal Articles

High Grade B-Cell Lymphoma with BCL2 and MYC Rearrangement (Double-Hit High-Grade Lymphoma; DH-HGL): Establishment of a Human Model System for Ex Vivo and In Vivo Studies

Alisa Maier, Lukas Ulrich, Binje Vick, William David Keay, Johannes Adrian Hildebrand, Carolin Dorothea Strobl, Verena Passerini, Louisa Adolph, Michael Heide, Tabea Felicitas Freyholdt, Gerulf Hänel, Axel Lechner, Susanne Thieme, Leon Kaulen, Louisa von Baumgarten, Daniel J Hodson, Martina Rudelius, Irmela Jeremias, Oliver Weigert
Journal: Blood
Blood (2024) 144 (Supplement 1): 2957.
https://doi.org/10.1182/blood-2024-194493
Published: 2024
Journal Articles

Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies

Johannes Adrian Hildebrand, Sarah Haebe, Verena Passerini, Michael Heide, William Keay, Louisa Adolph, Lukas Ulrich, Natyra Tahiri, Raphael Koch, Jessica Duffy, Haley Martin, Liam Hackett, Jeremy Zhang, Christina Ludwig, Stefanie Wilhelm, Björn Häupl, Carmen Doebele, Michael von Bergwelt-Baildon, Axel Lechner, Tobias Herold, Christian Kellner, Martina Rudelius, Thomas Oellerich, Marc Schmidt-Supprian, Abner Louissaint, Matthew S Davids, Oliver Weigert
Journal: Blood
Blood (2023) 142 (Supplement 1): 4358.
https://doi.org/10.1182/blood-2023-174384
Published: 2023
Journal Articles

The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL

Johanna Stachelscheid, Qu Jiang, Christoph Aszyk, Kathrin Warner, Nadine Bley, Tony Müller, Olga Vydzhak, Konstantinos Symeonidis, Giuliano Crispatzu, Petra Mayer, Stuart James Blakemore, Gudrun Goehring, Sebastian Newrzela, Stephanie Hippler, Sandra Robrecht, Karl-Anton Kreuzer, Christian Pallasch, Marcus Krüger, Axel Lechner, Kirsten Fischer, Stephan Stilgenbauer, Dirk Beutner, Michael Hallek, Daniel Auguin, Stefan Hüttelmaier, Johannes Bloehdorn, Elena Vasyutina, Marco Herling
Journal: Blood
Blood (2023) 141 (12): 1425–1441.
https://doi.org/10.1182/blood.2022015494
Published: 2023
Includes: Supplemental data
Journal Articles

CHOP but Not Bendamustine Reverses EZH2 Y641 Mutation Induced MHC-I/II Loss in Human Lymphoma Models

Louisa Catharina Adolph, Quentin Fichaux, Carolin Dorothea Strobl, Martina Antoniolli, Verena Passerini, William David Keay, Vindi Jurinovic, Axel Lechner, Daniel J. Hodson, Michael von Bergwelt, Marion Subklewe, Martina Rudelius, Oliver Weigert
Journal: Blood
Blood (2021) 138 (Supplement 1): 2391.
https://doi.org/10.1182/blood-2021-144803
Published: 2021