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Gudrun Goehring
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Journal Articles

The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL

Johanna Stachelscheid, Qu Jiang, Christoph Aszyk, Kathrin Warner, Nadine Bley, Tony Müller, Olga Vydzhak, Konstantinos Symeonidis, Giuliano Crispatzu, Petra Mayer, Stuart James Blakemore, Gudrun Goehring, Sebastian Newrzela, Stephanie Hippler, Sandra Robrecht, Karl-Anton Kreuzer, Christian Pallasch, Marcus Krüger, Axel Lechner, Kirsten Fischer, Stephan Stilgenbauer, Dirk Beutner, Michael Hallek, Daniel Auguin, Stefan Hüttelmaier, Johannes Bloehdorn, Elena Vasyutina, Marco Herling
Journal: Blood
Blood (2023) 141 (12): 1425–1441.
https://doi.org/10.1182/blood.2022015494
Published: 2023
Includes: Supplemental data
Journal Articles

Mutational Profile and Karyotypic Abnormalities of a Cohort of Clinical Trial Patients with Higher-Risk Myelodysplastic Syndromes (MDS) Following Failure of Hypomethylating Agents (HMAs): Impact on Response to Rigosertib Therapy

Ghulam J Mufti, FRCP, FRCPath, MD, Steven Best, PhD, Nicholas Lea, PhD, Lewis R. Silverman, MD, Guillermo Garcia-Manero, MD, Nozar Azarnia, PhD, Francois Wilhelm, MD PhD, Gudrun Goehring, MD
Journal: Blood
Blood (2014) 124 (21): 3258.
https://doi.org/10.1182/blood.V124.21.3258.3258
Published: 2014
Journal Articles

The Metabolite R-2-Hydroxyglutarate (R2HG) Collaborates with HoxA9 to Induce Monocytic Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, PhD, Ramya Goparaju, Vishwas Sharma, PhD, Adrian Schwarzer, MDPhD, Kerstin Goerlich, Renate Schottmann, Eduard A. Struys, PhD, Erwin E. Jansen, Robert Geffers, PhD, Gudrun Goehring, MD, Felicitas Thol, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 366.
https://doi.org/10.1182/blood.V124.21.366.366
Published: 2014
Journal Articles

Casein Kinase 1A1 (CSNK1A1) Is Recurrently Mutated in MDS Patients with Deletion of Chromosome 5q

Michael Heuser, MD, Manja Meggendorfer, PhD, Michelle Maria Araujo Cruz, Larissa Koehler, Gudrun Goehring, MD, Christina Ganster, Annika Gutermuth, Victoria Panagiota, MD, Jana Fabisch, Claudia Haferlach, MD, Christian Koenecke, MD, Uwe Platzbecker, Christian Thiede, MD, Ulrich Germing, Thomas Schroeder, MD, Guido Kobbe, MD, Steve Ehrlich, MD, Kathrin Stamer, MD, Brigitte Schlegelberger, MD, Nicolaus Kröger, MD, Arnold Ganser, Detlef Haase, Torsten Haferlach, Felicitas Thol, MD
Journal: Blood
Blood (2014) 124 (21): 4643.
https://doi.org/10.1182/blood.V124.21.4643.4643
Published: 2014
Journal Articles

The Clinical and Prognostic Influence Of Mutations In The Cohesin Complex In Acute Myeloid Leukemia

Felicitas Thol, MD, Robin Bollin, Marten Gehlhaar, Carolin Walter, Martin Dugas, MD, Karl Suchanek, Aylin Kirchner, Liu Huang, Anuhar Chaturvedi, PhD, Martin Wichmann, Lutz Wiehlmann, Frederik Damm, MD, Gudrun Goehring, Brigitte Schlegelberger, MD, PhD, Richard F. Schlenk, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Jürgen Krauter, MD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2013) 122 (21): 1314.
https://doi.org/10.1182/blood.V122.21.1314.1314
Published: 2013
Journal Articles

Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG)

Verena I. Gaidzik, Richard F. Schlenk, Peter Paschka, Anja Stölzle, Daniela Späth, Andrea Kuendgen, Marie von Lilienfeld-Toal, Wolfram Brugger, Hans Günter Derigs, Stephan Kremers, Richard Greil, Aruna Raghavachar, Mark Ringhoffer, Helmut R. Salih, Mohammed Wattad, Heinz G. Kirchen, Volker Runde, Gerhard Heil, Andreas L. Petzer, Michael Girschikofsky, Michael Heuser, Sabine Kayser, Gudrun Goehring, Maria-Veronica Teleanu, Brigitte Schlegelberger, Arnold Ganser, Jürgen Krauter, Lars Bullinger, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2013) 121 (23): 4769–4777.
https://doi.org/10.1182/blood-2012-10-461624
Published: 2013
Includes: Supplemental data
Journal Articles

Lenalidomide reexposure After Short Interruption In Del(5q) MDS Patients at Relapse of Transfusion Dependence

Robert Marek Radkowski, Sabine Haase, Brigitte Schlegelberger, MD, PhD, Gudrun Goehring, Stefanie Banisch, MD, Michael Heinsch, Carlo Aul, Aristoteles Giagounidis
Journal: Blood
Blood (2010) 116 (21): 2923.
https://doi.org/10.1182/blood.V116.21.2923.2923
Published: 2010
Journal Articles

Favorable Prognostic Impact of WT1 SNP rs16754 in Cytogenetically Normal AML Independent of MN1, BAALC, and ERG Expression.

Frederik Damm, M.D., Juergen Krauter, Iyas Hamwi, Michael A. Morgan, Ph.D., Gudrun Goehring, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2009) 114 (22): 1622.
https://doi.org/10.1182/blood.V114.22.1622.1622
Published: 2009
Journal Articles

RBC Transfusion Independence and Safety Profile of Lenalidomide 5 or 10 mg in Pts with Low- or Int-1-Risk MDS with Del5q: Results From a Randomized Phase III Trial (MDS-004).

Pierre Fenaux, Aristotle Giagounidis, Dominik Selleslag, MD, Odile Beyne-Rauzy, MD, PhD, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath, Moshe Mittelman, MD, Petra Muus, MD, PhD, Peter te Boekhorst, MD, PhD, Guillermo Sanz, MD, PhD, Consuelo del Cañizo, Agnes Guerci-Bresler, Brigitte Schlegelberger, M.D., Carlo Aul, Hans Kreipe, MD, Gudrun Goehring, Robert Knight, MD, John Francis, Tommy Fu, Eva Hellstrom-Lindberg, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 944.
https://doi.org/10.1182/blood.V114.22.944.944
Published: 2009
Journal Articles

Secondary AML After a History of Myelodysplastic Syndrome Is An Independent Adverse Prognostic Factor for Achievement of Complete Remission, Relapse-Free and Overall Survival. An Analysis of 2,819 Adult Patients with Newly Diagnosed AML Enrolled On Seven AMLSG Treatment Trials.

Sabine Kayser, Konstanze Doehner, Juergen Krauter, Heinz A. Horst, Marie von Lilienfeld-Toal, Ulrich Germing, Katharina Goetze, Michael Pfreundschuh, Walter Fiedler, MD, Daniela Spaeth, Silja Groner, Brigitte Schlegelberger, Gudrun Goehring, Arnold Ganser, MD, Hartmut Doehner, Richard F. Schlenk
Journal: Blood
Blood (2009) 114 (22): 2621.
https://doi.org/10.1182/blood.V114.22.2621.2621
Published: 2009
Journal Articles

Treatment-Related AML Is An Independent Adverse Prognostic Factor for Relapse-Free and Overall Survival. An Analysis of 2,868 Adult Patients with Newly Diagnosed AML Enrolled On Seven AMLSG Treatment Trials.

Sabine Kayser, Konstanze Doehner, Juergen Krauter, Heinz A. Horst, Marie von Lilienfeld-Toal, Ulrich Germing, Katharina Goetze, Michael Pfreundschuh, Walter Fiedler, MD, Daniela Spaeth, Silja Groner, Brigitte Schlegelberger, Gudrun Goehring, Arnold Ganser, MD, Hartmut Doehner, Richard F. Schlenk
Journal: Blood
Blood (2009) 114 (22): 578.
https://doi.org/10.1182/blood.V114.22.578.578
Published: 2009
Journal Articles

Phase I/II Gene Therapy Study for Chronic Granulomatous Disease: Results, Lessons and Perspectives.

Marion G. Ott, MD, Stefan Stein, PhD, Stephan Schultze-Strasser, Anna Jauch, PhD, Barbara Burwinkel, PhD, Brigitte Schlegelberger, PhD, Gudrun Goehring, PhD, Carolin Preiss, Rolf Kramer, Kerstin Schwarzwaelder, PhD, Ulrike Koehl, PhD, Hanna Kunkel, Klaus Kuehlcke, PhD, Andrea Schilz, PhD, Manfred Schmidt, PhD, Christof von Kalle, MD, Adrian Trasher, MD, Dieter Hoelzer, MD, Reinhard Seger, MD, Manuel Grez, PhD
Journal: Blood
Blood (2007) 110 (11): 503.
https://doi.org/10.1182/blood.V110.11.503.503
Published: 2007