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Michelle Maria Araujo Cruz
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Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2018-99-110159
Published: 2018
Journal Articles

Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, PhD, Ramya Goparaju, PhD, Razif Gabdoulline, Renate Schottmann, Kerstin Görlich, Arnold Kloos, Felicitas Thol, MD, Robert Geffers, PhD, Dimitrios Mougiakakos, Peter Carmeliet, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 759.
https://doi.org/10.1182/blood-2018-99-110425
Published: 2018
Journal Articles

Impact of Molecular Genetics on Disease-Free Survival in Myelofibrosis Patients Following Allogeneic Stem Cell Transplantation

Nicolaus Kroeger, MD, Victoria Panagiota, MD, Tatjana Zabelina, MD, Michelle Maria Araujo Cruz, MD, Rabia Shahswar, MD, Anita Badbaran, Ioanna N Triviai, PhD, Francis Ayuk, MD, Marten Gehlhaar, MD, Christine Wolschke, MD, Robin Bollin, MD, Ulrich Lehmann, MD, Christian Koenecke, MD, Anuhar Chaturvedi, PhD MS, BPharm, Haefaa Alchalby, MD, Michael Stadler, MD, Matthias Eder, MD, Maximilian Christopeit, MD, Gudrun Göhring, MD, Michael Koenigsmann, MD, Brigitte Schlegelberger, MD Prof., Hans Heinrich Kreipe, MD, Arnold Ganser, MD, Boris Fehse, PhD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2015) 126 (23): 352.
https://doi.org/10.1182/blood.V126.23.352.352
Published: 2015
Journal Articles

Casein Kinase 1A1 (CSNK1A1) Is Recurrently Mutated in MDS Patients with Deletion of Chromosome 5q

Michael Heuser, MD, Manja Meggendorfer, PhD, Michelle Maria Araujo Cruz, Larissa Koehler, Gudrun Goehring, MD, Christina Ganster, Annika Gutermuth, Victoria Panagiota, MD, Jana Fabisch, Claudia Haferlach, MD, Christian Koenecke, MD, Uwe Platzbecker, Christian Thiede, MD, Ulrich Germing, Thomas Schroeder, MD, Guido Kobbe, MD, Steve Ehrlich, MD, Kathrin Stamer, MD, Brigitte Schlegelberger, MD, Nicolaus Kröger, MD, Arnold Ganser, Detlef Haase, Torsten Haferlach, Felicitas Thol, MD
Journal: Blood
Blood (2014) 124 (21): 4643.
https://doi.org/10.1182/blood.V124.21.4643.4643
Published: 2014
Journal Articles

Prognostic Impact of Splicing Factor Mutations in Patients with Myelofibrosis Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Victoria Panagiota, MD, Michael Heuser, MD, Michelle Maria Araujo Cruz, Anita Badbaran, Rabia Shahswar, Ioanna N Triviai, PhD, Boris Fehse, MD, Haefaa Alchalby, MD, Ulrich Lehmann, MD, Christian Koenecke, MD, Anuhar Chaturvedi, PhD, Michael Stadler, MD, Matthias Eder, MD, Gudrun Göhring, MD, Michael Koenigsmann, MD, Brigitte Schlegelberger, MD, Hans Heinrich Kreipe, MD, Arnold Ganser, MD, Felicitas Thol, MD, Nicolaus Kröger, MD
Journal: Blood
Blood (2014) 124 (21): 3171.
https://doi.org/10.1182/blood.V124.21.3171.3171
Published: 2014
Journal Articles

A Novel Inhibitor of Mutant IDH1 Induces Differentiation in Vivo and Prolongs Survival in a Mouse Model of Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Ramya Goparaju, Nidhi Jyotsana, Heike Baehre, PhD, Kerstin Goerlich, Renate Schottmann, Matthias Preller, PhD, Eduard A. Struys, PhD, Arnold Kloos, PhD, Volkhard Kaever, PhD, Arnold Ganser, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 3598.
https://doi.org/10.1182/blood.V124.21.3598.3598
Published: 2014
Journal Articles

The Metabolite R-2-Hydroxyglutarate (R2HG) Collaborates with HoxA9 to Induce Monocytic Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, PhD, Ramya Goparaju, Vishwas Sharma, PhD, Adrian Schwarzer, MDPhD, Kerstin Goerlich, Renate Schottmann, Eduard A. Struys, PhD, Erwin E. Jansen, Robert Geffers, PhD, Gudrun Goehring, MD, Felicitas Thol, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 366.
https://doi.org/10.1182/blood.V124.21.366.366
Published: 2014
Journal Articles

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

Anuhar Chaturvedi, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, Matthias Preller, Felicitas Thol, Johann Meyer, Reinhard Haemmerle, Eduard A. Struys, Erwin E. Jansen, Ute Modlich, Zhixiong Li, Laura M. Sly, Robert Geffers, Robert Lindner, Dietmar J. Manstein, Ulrich Lehmann, Jürgen Krauter, Arnold Ganser, Michael Heuser
Journal: Blood
Blood (2013) 122 (16): 2877–2887.
https://doi.org/10.1182/blood-2013-03-491571
Published: 2013
Includes: Supplemental data
Journal Articles

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, MD, Matthias Preller, PhD, Felicitas Thol, MD, Johann Meyer, PhD, Reinhard Haemmerle, Eduard A. Struys, PhD, Erwin E. Jansen, Ute Modlich, DVM, PhD, Zhixiong Li, MD, Laura M. Sly, PhD, Robert Geffers, PhD, Robert Lindner, PhD, Dietmar J. Manstein, PhD, Urlich Lehmann, PhD, Jürgen Krauter, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2012) 120 (21): 770.
https://doi.org/10.1182/blood.V120.21.770.770
Published: 2012