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Journal Articles

Fla-IDA Chemotherapy with or without Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 3315–3316.

https://doi.org/10.1182/blood-2022-163430

Published: 2022

Journal Articles

Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 5259.

https://doi.org/10.1182/blood-2018-99-113037

Published: 2018

Journal Articles

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

Zengkai Pan, MD PhD, Min Yang, Kezhi Huang, MD PhD, Guntram Buesche, MD, Gudrun Göhring, MD, Michaela Scherr, PhD, Matthias Gaestel, PhD, Matthias Eder, MD, Julia Skokowa, MDPhD, Jianfeng Zhou, PhD, Karl Welte, Li-Gen Liu, MD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2018) 132 (Supplement 1): 771.

https://doi.org/10.1182/blood-2018-99-110770

Published: 2018

Journal Articles

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Kezhi Huang, Min Yang, Zengkai Pan, Florian H. Heidel, MD, Michaela Scherr, PhD, Matthias Eder, MD, Thomas Fischer, MD, Guntram Buesche, MD, Nils von Neuhoff, PhD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2015) 126 (23): 1383.

https://doi.org/10.1182/blood.V126.23.1383.1383

Published: 2015

Journal Articles

Targeting Rac-Gtpases Reverses Stroma-Induced Resistance to Notch and mTOR-Inhibition in Acute T-Cell Leukemia

Adrian Schwarzer, MD PhD, Martin May, Harald Genth, Zhixiong Li, MD, Christopher Baum, MD, Axel Schambach, MD PhD

Blood (2015) 126 (23): 1326.

https://doi.org/10.1182/blood.V126.23.1326.1326

Published: 2015

Journal Articles

Activation of TRKB receptor in murine hematopoietic stem/progenitor cells induced mastocytosis

Min Yang, Kezhi Huang, Guntram Büsche, Arnold Ganser, Zhixiong Li

Blood (2014) 124 (7): 1196–1197.

https://doi.org/10.1182/blood-2014-03-560466

Published: 2014

Includes: Supplemental data

Journal Articles

Investigating Synthetic Lethality Between mTOR Hyperactivation and Cap-Dependent mRNA Translation In a Receptor Tyrosine Kinase Driven Model Of Acute T-Cell Leukemia

Adrian Schwarzer, MD PhD, Helmut Holtmann, PhD, Celina Schauerte, M.Sc., Nomme Benn, Jan Völkel, Sabine Knöß, Johannes Zuber, MD, Zhixiong Li, MD, Axel Schambach, MD PhD, Christopher Baum, MD

Blood (2013) 122 (21): 3913.

https://doi.org/10.1182/blood.V122.21.3913.3913

Published: 2013

Journal Articles

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

Blood (2013) 122 (16): 2877–2887.

https://doi.org/10.1182/blood-2013-03-491571

Published: 2013

Includes: Supplemental data

Journal Articles

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Blood (2012) 120 (21): 770.

https://doi.org/10.1182/blood.V120.21.770.770

Published: 2012

Journal Articles

Receptor Tyrosine Kinases, Notch Mutations and PTEN Loss Converge On mTOR in T-ALL and Cause Addiction to Cap Dependent mRNA Translation.

Adrian Schwarzer, MD, Helmut Holtmann, PhD, Martijn Brugman, PhD, Johann Meyer, PhD, Doris Steinemann, PhD, Brigitte Schlegelberger, Zhixiong Li, MD, Christopher Baum, MD

Blood (2012) 120 (21): 2415.

https://doi.org/10.1182/blood.V120.21.2415.2415

Published: 2012

Journal Articles

Evidence for Cooperation of Receptor Tyrosine Kinases and Activating NOTCH Mutations to Hyperactivate mTOR in T-Cell Leukemia: A Rationale Basis for Targeted Therapy

Adrian Schwarzer, MD, Johann Meyer, PhD, Martijn Brugman, PhD, Axel Schambach, MD PhD, Martin Stanulla, MD, MSc, Martin Schrappe, MD, Doris Steinemann, PhD, Brigitte Schlegelberger, M.D., Christopher Baum, MD, Zhixiong Li, MD

Blood (2011) 118 (21): 1381.

https://doi.org/10.1182/blood.V118.21.1381.1381

Published: 2011

Journal Articles

Polyclonal fluctuation of lentiviral vector–transduced and expanded murine hematopoietic stem cells

Tobias Maetzig, Martijn H. Brugman, Stefan Bartels, Niels Heinz, Olga S. Kustikova, Ute Modlich, Zhixiong Li, Melanie Galla, Bernhard Schiedlmeier, Axel Schambach, Christopher Baum

Blood (2011) 117 (11): 3053–3064.

https://doi.org/10.1182/blood-2010-08-303222

Published: 2011

Includes: Supplemental data

Journal Articles

High-affinity neurotrophin receptors and ligands promote leukemogenesis

Zhixiong Li, Gernot Beutel, Mathias Rhein, Johann Meyer, Christian Koenecke, Thomas Neumann, Min Yang, Jürgen Krauter, Nils von Neuhoff, Michael Heuser, Helmut Diedrich, Gudrun Göhring, Ludwig Wilkens, Brigitte Schlegelberger, Arnold Ganser, Christopher Baum

Blood (2009) 113 (9): 2028–2037.

https://doi.org/10.1182/blood-2008-05-155200

Published: 2009

Includes: Supplemental data

Journal Articles

Leukemia Induced by Altered TRK-Signaling Is Sensitive to Rapamycin Treatment in a Preclinical Model

Mathias Rhein, Min Yang, Volkhard Kaever, PhD, Johann Meyer, PhD, Christopher Baum, MD, Zhixiong Li, MD

Blood (2008) 112 (11): 2851.

https://doi.org/10.1182/blood.V112.11.2851.2851

Published: 2008

Journal Articles

Ectopic Expression of the Extracellular Domain of Mpl Is Sufficient to Induce a Hematopoietic Population Crisis

Daniel C. Wicke, Johann Meyer, Guntram Büsche, MD, Hans Kreipe, MD, Zhixiong Li, MD, Karl Welte, Matthias Ballmaier, Christopher Baum, Ute Modlich

Blood (2008) 112 (11): 2886.

https://doi.org/10.1182/blood.V112.11.2886.2886

Published: 2008

Journal Articles

Cell-Intrinsic Heterogeneity Plays An Important Role in the Development of Clonal Dominance after Retroviral Gene Transfer into Hematopoietic Stem Cells

Olga S. Kustikova, Bernhard Schiedlmeier, Martijn H. Brugman, Maike Stahlhut, Zhixiong Li, Christopher Baum

Blood (2008) 112 (11): 819.

https://doi.org/10.1182/blood.V112.11.819.819

Published: 2008

Journal Articles

Resistance of mature T cells to oncogene transformation

Sebastian Newrzela, Kerstin Cornils, Zhixiong Li, Christopher Baum, Martijn H. Brugman, Marianne Hartmann, Johann Meyer, Sylvia Hartmann, Martin-Leo Hansmann, Boris Fehse, Dorothee von Laer

Blood (2008) 112 (6): 2278–2286.

https://doi.org/10.1182/blood-2007-12-128751

Published: 2008

Includes: Supplemental data

Journal Articles

The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress

Deidre Daria, Marie-Dominique Filippi, Erik S. Knudsen, Roberta Faccio, Zhixiong Li, Theodosia Kalfa, Hartmut Geiger

Blood (2008) 111 (4): 1894–1902.

https://doi.org/10.1182/blood-2007-02-071746

Published: 2008

Includes: Supplemental data

Journal Articles

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

Zhixiong Li, MD, Gernot Beutel, MD, Johann Meyer, PhD, Christian Koenecke, MD, Thomas Neumann, Min Yang, Juergen Krauter, MD, Mathias Rhein, Msc, Nils von Neuhoff, PhD, Michael Heuser, MD, Helmut Diedrich, MD, Ludwig Wilkens, MD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Christopher Baum, MD

Blood (2007) 110 (11): 696.

https://doi.org/10.1182/blood.V110.11.696.696

Published: 2007

Journal Articles

Retroviral vector insertion sites associated with dominant hematopoietic clones mark “stemness” pathways

Olga S. Kustikova, Hartmut Geiger, Zhixiong Li, Martijn H. Brugman, Stuart M. Chambers, Chad A. Shaw, Karin Pike-Overzet, Dick de Ridder, Frank J. T. Staal, Gottfried von Keudell, Kerstin Cornils, Kalpana Jekumar Nattamai, Ute Modlich, Gerard Wagemaker, Margaret A. Goodell, Boris Fehse, Christopher Baum

Blood (2006) 109 (5): 1897–1907.

https://doi.org/10.1182/blood-2006-08-044156

Published: 2006

Includes: Supplemental data

NARROW

Fla-IDA Chemotherapy with or without Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Targeting Rac-Gtpases Reverses Stroma-Induced Resistance to Notch and mTOR-Inhibition in Acute T-Cell Leukemia

Activation of TRKB receptor in murine hematopoietic stem/progenitor cells induced mastocytosis

Investigating Synthetic Lethality Between mTOR Hyperactivation and Cap-Dependent mRNA Translation In a Receptor Tyrosine Kinase Driven Model Of Acute T-Cell Leukemia

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Receptor Tyrosine Kinases, Notch Mutations and PTEN Loss Converge On mTOR in T-ALL and Cause Addiction to Cap Dependent mRNA Translation.

Evidence for Cooperation of Receptor Tyrosine Kinases and Activating NOTCH Mutations to Hyperactivate mTOR in T-Cell Leukemia: A Rationale Basis for Targeted Therapy

Polyclonal fluctuation of lentiviral vector–transduced and expanded murine hematopoietic stem cells

High-affinity neurotrophin receptors and ligands promote leukemogenesis

Leukemia Induced by Altered TRK-Signaling Is Sensitive to Rapamycin Treatment in a Preclinical Model

Ectopic Expression of the Extracellular Domain of Mpl Is Sufficient to Induce a Hematopoietic Population Crisis

Cell-Intrinsic Heterogeneity Plays An Important Role in the Development of Clonal Dominance after Retroviral Gene Transfer into Hematopoietic Stem Cells

Resistance of mature T cells to oncogene transformation

The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

Retroviral vector insertion sites associated with dominant hematopoietic clones mark “stemness” pathways

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American Society of Hematology

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ASH Publications

American Society of Hematology

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