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Journal Articles

Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia

Nicola Gökbuget, Hervé Dombret, Massimiliano Bonifacio, Albrecht Reichle, Carlos Graux, Christoph Faul, Helmut Diedrich, Max S. Topp, Monika Brüggemann, Heinz-August Horst, Violaine Havelange, Julia Stieglmaier, Hendrik Wessels, Vincent Haddad, Jonathan E. Benjamin, Gerhard Zugmaier, Dirk Nagorsen, Ralf C. Bargou

Blood (2018) 131 (14): 1522–1531.

https://doi.org/10.1182/blood-2017-08-798322

Published: 2018

Includes: Supplemental data

Journal Articles

Long-term survival and T-cell kinetics in relapsed/refractory ALL patients who achieved MRD response after blinatumomab treatment

Gerhard Zugmaier, Nicola Gökbuget, Matthias Klinger, Andreas Viardot, Matthias Stelljes, Svenja Neumann, Heinz-A. Horst, Reinhard Marks, Christoph Faul, Helmut Diedrich, Albrecht Reichle, Monika Brüggemann, Chris Holland, Margit Schmidt, Hermann Einsele, Ralf C. Bargou, Max S. Topp

Blood (2015) 126 (24): 2578–2584.

https://doi.org/10.1182/blood-2015-06-649111

Published: 2015

Includes: Supplemental data

Journal Articles

Long-Term Outcomes after Blinatumomab Treatment: Follow-up of a Phase 2 Study in Patients (Pts) with Minimal Residual Disease (MRD) Positive B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)

Nicola Gökbuget, MD, Hervé Dombret, MDPhD, Massimiliano Bonifacio, MD, Albrecht Reichle, MD, Carlos Graux, MDPhD, Christoph Faul, MD, Helmut Diedrich, MD, Max S. Topp, MD, Monika Brüggemann, MD, Heinz A. Horst, MD PhD, Julia Stieglmaier, PhD, Hendrik Wessels, MD, Vincent Haddad, MSc, Gerhard Zugmaier, MD, Dirk Nagorsen, MD, Ralf C Bargou, MD

Blood (2015) 126 (23): 680.

https://doi.org/10.1182/blood.V126.23.680.680

Published: 2015

Journal Articles

Significant Improvement Of Outcome In Adolescents and Young adults (AYAs) Aged 15-35 Years With Acute Lymphoblastic Leukemia (ALL) With a Pediatric Derived Adult ALL Protocol; Results Of 1529 AYAs In 2 Consecutive Trials Of The German Multicenter Study Group For Adult ALL (GMALL)

Blood (2013) 122 (21): 839.

https://doi.org/10.1182/blood.V122.21.839.839

Published: 2013

Journal Articles

Prognostic Value Of Plasma Biomarkers Compared To Urinary Proteome Patterns

Christin Human, Sylvia Borchers, PhD, Michael Stadler, MD, Helmut Diedrich, Jürgen Krauter, MD, PhD, Christine Falk, Arnold Ganser, Eva M Weissinger, MD

Blood (2013) 122 (21): 4593.

https://doi.org/10.1182/blood.V122.21.4593.4593

Published: 2013

Journal Articles

Investigation of Urine/Plasma Biomarkers to Predict Tolerance and Graft-Versus-Host Disease Post Allogeneic Stem Cell Transplantation.

Christin Human, Sylvia Borchers, PhD, Michael Stadler, MD, Helmut Diedrich, Jürgen Krauter, MD, PhD, Christine Falk, Arnold Ganser, Eva M Mischak-Weissinger, MD

Blood (2012) 120 (21): 3049.

https://doi.org/10.1182/blood.V120.21.3049.3049

Published: 2012

Journal Articles

Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation

Blood (2012) 120 (10): 2032–2041.

https://doi.org/10.1182/blood-2011-12-399287

Published: 2012

Includes: Supplemental data

Journal Articles

Prospective Validation of a Chronic GvHD-Specific Proteome Pattern (cGvHD-MS14) Post Allogeneic Hematopoietic Stem Cell Transplantation

Eva M. Weissinger, MD, Daniel Wolff, Jochen Metzger, Christiane E Dobbelstein, MD, Stefanie Buchholz, MD, Elke Dammann, Uwe Borchert, Annika Krons, Helmut Diedrich, Michael Stadler, MD, Anne M Dickinson, PhD, Ernst Holler, M.D., Hildegard T. Greinix, MD, Juergen Krauter, MD, Arnold Ganser, MD

Blood (2011) 118 (21): 1970.

https://doi.org/10.1182/blood.V118.21.1970.1970

Published: 2011

Journal Articles

High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation

Nicola Gökbuget, Nadezda Basara, Herrad Baurmann, Joachim Beck, Monika Brüggemann, Helmut Diedrich, Björn Güldenzoph, Gernot Hartung, Heinz-August Horst, Andreas Hüttmann, Guido Kobbe, Ralph Naumann, Richard Ratei, Albrecht Reichle, Hubert Serve, Matthias Stelljes, Andreas Viardot, Mohammed Wattad, Dieter Hoelzer

Blood (2011) 118 (13): 3504–3511.

https://doi.org/10.1182/blood-2011-01-329441

Published: 2011

Journal Articles

PEG-Asparaginase Intensification In Adult Acute Lymphoblastic Leukemia (ALL): Significant Improvement of Outcome with Moderate Increase of Liver Toxicity In the German Multicenter Study Group for Adult ALL (GMALL) Study 07/2003

Nicola Goekbuget, MD, Anja Baumann, MD, Joachim Beck, MD, Monika Brueggemann, MD, Helmut Diedrich, MD, Andreas Huettmann, MD, Lothar Leimer, MD, Stefan Zewen, MD, Martin Mohren, MD, Albrecht Reichle, MD, Markus Schaich, MD, Kerstin Schaefer-Eckart, MD, Marc Schmalzing, MD, Mathias Schmid, MD, Hubert Serve, MD, Reingard Stuhlmann, MD, Theis H Terwey, MD, Dieter Hoelzer, MD

Blood (2010) 116 (21): 494.

https://doi.org/10.1182/blood.V116.21.494.494

Published: 2010

Journal Articles

Proteomic Screening Applied to the Diagnosis of Chronic Graft-Versus-Host-Disease.

Eva M. Mischak-Weissinger, MD, Michael Stadler, MD, Ernst Holler, PhD, Michael Schleuning, Hildegard Greinix, MD, Hans-Jochem Kolb, MD, Anne M Dickinson, PhD, Annika Krons, Helmut Diedrich, MD, Julia Kontsendorn, Norbert Hahn, Jochen Metzger, PhD, Arnold Ganser, MD

Blood (2009) 114 (22): 1164.

https://doi.org/10.1182/blood.V114.22.1164.1164

Published: 2009

Journal Articles

Limited efficacy of imatinib in severe pulmonary chronic graft-versus-host disease

Michael Stadler, Renate Ahlborn, Haytham Kamal, Helmut Diedrich, Stefanie Buchholz, Matthias Eder, Arnold Ganser

Blood (2009) 114 (17): 3718–3719.

https://doi.org/10.1182/blood-2009-07-231159

Published: 2009

Journal Articles

High-affinity neurotrophin receptors and ligands promote leukemogenesis

Zhixiong Li, Gernot Beutel, Mathias Rhein, Johann Meyer, Christian Koenecke, Thomas Neumann, Min Yang, Jürgen Krauter, Nils von Neuhoff, Michael Heuser, Helmut Diedrich, Gudrun Göhring, Ludwig Wilkens, Brigitte Schlegelberger, Arnold Ganser, Christopher Baum

Blood (2009) 113 (9): 2028–2037.

https://doi.org/10.1182/blood-2008-05-155200

Published: 2009

Includes: Supplemental data

Journal Articles

PEG-Asparaginase in Adult Acute Lymphoblastic Leukemia (ALL): Efficacy and Feasibility Analysis with Increasing Dose Levels

Nicola Goekbuget, MD, Anja Baumann, MD, Joachim Beck, MD, Joachim Boos, MD, PhD, Monika Brueggemann, MD, PhD, Helmut Diedrich, MD, Andreas Hüttmann, MD, Lothar Leimer, MD, Thomas Lipp, MD, Ralph Naumann, MD, PhD, Martin Mohren, MD, Albrecht Reichle, MD, PhD, Kerstin Schäfer-Eckart, MD, Marc Schmalzing, MD, Mathias Schmid, MD, PhD, Norbert Schmitz, MD, PhD, Theis Therwey, MD, Dieter Hoelzer, MD, PhD

Blood (2008) 112 (11): 302.

https://doi.org/10.1182/blood.V112.11.302.302

Published: 2008

Journal Articles

Extramedullary Acute Leukemias prior to and after Allogeneic Hematopoietic Stem Cell Transplantation: a Single Center Study.

Michael Stadler, MD, PhD, Helmut Diedrich, MD, Elke Dammann, Stefanie Buchholz, MD, Eva Mischak-Weissinger, MD, PhD, Juergen Krauter, MD, PhD, Matthias Eder, MD, PhD, Arnold Ganser, MD, PhD

Blood (2008) 112 (11): 3262.

https://doi.org/10.1182/blood.V112.11.3262.3262

Published: 2008

Journal Articles

General Condition and Early Complications Have in Addition to Disease- Specific Factors a Significant Impact on Outcome - Prognostic Factors Revisited in 1657 Adult ALL Patients (15–55 years).

Blood (2008) 112 (11): 1927.

https://doi.org/10.1182/blood.V112.11.1927.1927

Published: 2008

Journal Articles

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

Zhixiong Li, MD, Gernot Beutel, MD, Johann Meyer, PhD, Christian Koenecke, MD, Thomas Neumann, Min Yang, Juergen Krauter, MD, Mathias Rhein, Msc, Nils von Neuhoff, PhD, Michael Heuser, MD, Helmut Diedrich, MD, Ludwig Wilkens, MD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Christopher Baum, MD

Blood (2007) 110 (11): 696.

https://doi.org/10.1182/blood.V110.11.696.696

Published: 2007

Journal Articles

CD10 - pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German Multicenter Trials for Adult ALL (GMALL)

Beate Gleissner, Nicola Goekbuget, Harald Rieder, Renate Arnold, Stefan Schwartz, Helmut Diedrich, Claudia Schoch, Barbara Heinze, Christa Fonatsch, Claus R. Bartram, Dieter Hoelzer, Eckhard Thiel, for the GMALL Study Group

Blood (2005) 106 (13): 4054–4056.

https://doi.org/10.1182/blood-2005-05-1866

Published: 2005

Journal Articles

Dexamethasone Dose and Schedule Significantly Influences Remission Rate and Toxicity of Induction Therapy in Adult Acute Lymphoblastic Leukemia (ALL): Results of the GMALL Pilot Trial 06/99.

Nicola Goekbuget, MD, Karl-Heinz Baur, MD, Joachim Beck, MD, Helmut Diedrich, MD, Monika Lamprecht, MD, Lothar Leimer, MD, Thomas Lipp, MD, Jutta Neteler, MD, Regina Reutzel, Jan Rutjes, MD, Mathias Schmid, MD, Peter Staib, MD, Matthias Stelljes, MD, Dieter Hoelzer, MD

Blood (2005) 106 (11): 1832.

https://doi.org/10.1182/blood.V106.11.1832.1832

Published: 2005

Journal Articles

Immunophenotypic and Genotypic Features, Clinical Characteristics, and Treatment Outcome of Adult Pro-B Acute Lymphoblastic Leukemia: Results of the German Multicenter Trials GMALL 03/87 and 04/89

Blood (1998) 92 (6): 1898–1909.

https://doi.org/10.1182/blood.V92.6.1898

Published: 1998

NARROW

Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia

Long-term survival and T-cell kinetics in relapsed/refractory ALL patients who achieved MRD response after blinatumomab treatment

Long-Term Outcomes after Blinatumomab Treatment: Follow-up of a Phase 2 Study in Patients (Pts) with Minimal Residual Disease (MRD) Positive B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)

Significant Improvement Of Outcome In Adolescents and Young adults (AYAs) Aged 15-35 Years With Acute Lymphoblastic Leukemia (ALL) With a Pediatric Derived Adult ALL Protocol; Results Of 1529 AYAs In 2 Consecutive Trials Of The German Multicenter Study Group For Adult ALL (GMALL)

Prognostic Value Of Plasma Biomarkers Compared To Urinary Proteome Patterns

Investigation of Urine/Plasma Biomarkers to Predict Tolerance and Graft-Versus-Host Disease Post Allogeneic Stem Cell Transplantation.

Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation

Prospective Validation of a Chronic GvHD-Specific Proteome Pattern (cGvHD-MS14) Post Allogeneic Hematopoietic Stem Cell Transplantation

High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation

PEG-Asparaginase Intensification In Adult Acute Lymphoblastic Leukemia (ALL): Significant Improvement of Outcome with Moderate Increase of Liver Toxicity In the German Multicenter Study Group for Adult ALL (GMALL) Study 07/2003

Proteomic Screening Applied to the Diagnosis of Chronic Graft-Versus-Host-Disease.

Limited efficacy of imatinib in severe pulmonary chronic graft-versus-host disease

High-affinity neurotrophin receptors and ligands promote leukemogenesis

PEG-Asparaginase in Adult Acute Lymphoblastic Leukemia (ALL): Efficacy and Feasibility Analysis with Increasing Dose Levels

Extramedullary Acute Leukemias prior to and after Allogeneic Hematopoietic Stem Cell Transplantation: a Single Center Study.

General Condition and Early Complications Have in Addition to Disease- Specific Factors a Significant Impact on Outcome - Prognostic Factors Revisited in 1657 Adult ALL Patients (15–55 years).

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

CD10 - pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German Multicenter Trials for Adult ALL (GMALL)

Dexamethasone Dose and Schedule Significantly Influences Remission Rate and Toxicity of Induction Therapy in Adult Acute Lymphoblastic Leukemia (ALL): Results of the GMALL Pilot Trial 06/99.

Immunophenotypic and Genotypic Features, Clinical Characteristics, and Treatment Outcome of Adult Pro-B Acute Lymphoblastic Leukemia: Results of the German Multicenter Trials GMALL 03/87 and 04/89

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American Society of Hematology

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American Society of Hematology

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