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Journal Articles

Chemotherapy or Stem Cell Transplantation in Adult High Risk Ph/BCR::ABL1-Negative ALL Patients with Early MRD Negativity: Results of the Randomized GMALL Trial 08/2013

Nicola Goekbuget, Folker Schneller, Kathrin Nachtkamp, Sr., Joachim Beck, Christoph Faul, Ralph Wäsch, Tobias Gaska, Lisa Heberling, Knut Wendelin, Thomas Kubin, Sonja Martin, Lino L. Teichmann, Veit L. Buecklein, Walter Fiedler, Christian Junghanss, Claudia D Baldus, Monika Brüggemann, Stefan Schwartz, Axel Benner, Nicholas Schreck, Lena Reiser, Hubert Serve, Andreas Viardot
Journal: Blood
Blood (2024) 144 (Supplement 1): 961.
https://doi.org/10.1182/blood-2024-199060
Published: 2024
Journal Articles

Pregnancies and Childbirth Following Advanced-Stage Hodgkin Lymphoma Treatment with Brecadd or Beacopp in the Randomized Phase III GHSG HD21 Trial

Justin Ferdinandus, Gundolf Schneider, Alexander Fosså, Alden Moccia, Richard Greil, Mark S. Hertzberg, Josée M. Zijlstra, Peter Kamper, Daniel L. Molin, Andrea Kerkhoff, Sebastian Scholl, Yon-Dschun Ko, Max S. Topp, Joachim Beck, Vladan Vucinic, Wolfram Jung, Roland Schroers, Andreas Rank, Carla Damaschin, Anne Sophie Jacob, Michael Fuchs, Peter Borchmann, Karolin Behringer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4437.
https://doi.org/10.1182/blood-2023-188449
Published: 2023
Journal Articles

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Nicola Goekbuget, Walter Fiedler, Nael Alakel, Max S. Topp, Maher Hanoun, Björn Steffen, Ralph Wäsch, Andreas Viardot, Kathrin Nachtkamp, Matthias Stelljes, Hendrik Poeck, Vladan Vucinic, Boris Böll, Joachim Beck, Lars Fransecky, Knut Wendelin, Folker Schneller, Christoph Faul, Veit L Buecklein, Lena Reiser, Monika Brüggemann, Hubert Serve, Stefan Schwartz
Journal: Blood
Blood (2022) 140 (Supplement 1): 115–117.
https://doi.org/10.1182/blood-2022-158381
Published: 2022
Journal Articles

First Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 705 Adults with Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL/LBL)

Nicola Goekbuget, Matthias Stelljes, Andreas Viardot, Kathrin Nachtkamp, Björn Steffen, Folker Schneller, Nael Alakel, Max Topp, Boris Böll, Christoph Faul, Karsten Spiekermann, Knut Wendelin, Maher Hanoun, Ralph Wäsch, Joachim Beck, Sonja Martin, Vladan Vucinic, Claudia D. Baldus, Monika Brüggemann, Thomas Burmeister, Heike Pfeifer, Stefan Schwartz, Lena Baumann, Diana Tichy, Hubert Serve, Walter Fiedler
Journal: Blood
Blood (2021) 138 (Supplement 1): 362.
https://doi.org/10.1182/blood-2021-146306
Published: 2021
Journal Articles

Nilotinib (Tasigna ® ) and Low Intensity Chemotherapy for First-Line Treatment of Elderly Patients with BCR-ABL1- Positive Acute Lymphoblastic Leukemia: Final Results of a Prospective Multicenter Trial (EWALL-PH02)

Oliver G. Ottmann, MD, Heike Pfeifer, MD, Jean-Michel Cayuela, PhD, Karsten Spiekermann, MD, Wolfram Jung, MD, Joachim Beck, Emmanuel Raffoux, MD, Pascal Turlure, MD, Chantal Himberlin, Francoise Huguet, MD, Andreas Viardot, MD, Knut Wendelin, MD, Albrecht Reichle, MD, Sébastien Maury, MD PhD, Laurence Sanhes, MD, Francoise Isnard, PhD, Jean-Yves Cahn, MD, Stephane Lepretre, Patrice Chevallier, MD, Martine Escoffre-Barbe, MD, Josep-Maria Ribera, MD PhD, Dieter Hoelzer, MD PhD, Nicola Goekbuget, MD, Hervé Dombret, Philippe Rousselot, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 31.
https://doi.org/10.1182/blood-2018-99-114552
Published: 2018
Journal Articles

Genomic CDKN2A/2B deletions in adult Ph + ALL are adverse despite allogeneic stem cell transplantation

Heike Pfeifer, Katharina Raum, Sandra Markovic, Verena Nowak, Stephanie Fey, Julia Obländer, Jovita Pressler, Verena Böhm, Monika Brüggemann, Lydia Wunderle, Andreas Hüttmann, Ralph Wäsch, Joachim Beck, Matthias Stelljes, Andreas Viardot, Fabian Lang, Dieter Hoelzer, Wolf-Karsten Hofmann, Hubert Serve, Christel Weiss, Nicola Goekbuget, Oliver G. Ottmann, Daniel Nowak
Journal: Blood
Blood (2018) 131 (13): 1464–1475.
https://doi.org/10.1182/blood-2017-07-796862
Published: 2018
Includes: Supplemental data
Journal Articles

Evaluation of Minimal Residual Disease (MRD) and MRD-Based Treatment Decisions in Ph/BCR-ABL Negative Adult Acute Lymphoblastic Leukemia (ALL): Experience from the German Multicenter Study Group for Adult ALL (GMALL)

Nicola Goekbuget, MD, Monika Brüggemann, Joachim Beck, MD, Christoph Faul, MD, Christian Koenecke, MD, Heinz A. Horst, MD PhD, Mustafa Kondakci, MD, Doris M. Kraemer, MD, PhD, Christoph Lutz, MD, Bernd Spriewald, MD, Michael Starck, MD, Christoph Rollig, MD MSC, Matthias Stelljes, MD, Andreas Viardot, MD, Ralph Wäsch, Knut Wendelin, MD, Hubert Serve, Michael Kneba, MD, Dieter Hoelzer, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 139.
https://doi.org/10.1182/blood.V130.Suppl_1.139.139
Published: 2017
Journal Articles

Detection of Clonal Hematopoiesis Is a Rare Event in Patients with Dyskeratosis Congenita

Martin Kirschner, MD, Angela Maurer, Marcin W. Wlodarski, MD PhD, Monica Sofia Ventura Ferreira, Anne-Sophie Bouillon, MD, Wolfgang Blau, Michael Kreuter, MD, Martin Rosewich, Selim Corbacioglu, MD PhD, Joachim Beck, MD, C. Matthias Wilk, MD, Steffen Koschmieder, Fabian Beier, MD, Tim H. Brummendorf, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2457.
https://doi.org/10.1182/blood.V130.Suppl_1.2457.2457
Published: 2017
Journal Articles

Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial

Clinical Trials & Observations
Dieter Hoelzer, Jan Walewski, Hartmut Döhner, Andreas Viardot, Wolfgang Hiddemann, Karsten Spiekermann, Hubert Serve, Ulrich Dührsen, Andreas Hüttmann, Eckhard Thiel, Jolanta Dengler, Michael Kneba, Markus Schaich, Ingo G. H. Schmidt-Wolf, Joachim Beck, Bernd Hertenstein, Albrecht Reichle, Katarzyna Domanska-Czyz, Rainer Fietkau, Heinz-August Horst, Harald Rieder, Stefan Schwartz, Thomas Burmeister, Nicola Gökbuget
Journal: Blood
Blood (2014) 124 (26): 3870–3879.
https://doi.org/10.1182/blood-2014-03-563627
Published: 2014
Includes: Supplemental data
Journal Articles

Nilotinib (Tasigna®) and Chemotherapy for First-Line Treatment in Elderly Patients with De Novo Philadelphia Chromosome/BCR-ABL1 Positive Acute Lymphoblastic Leukemia (ALL): A Trial of the European Working Group for Adult ALL (EWALL-PH-02)

Oliver G. Ottmann, MD, Heike Pfeifer, MD, Jean-Michel Cayuela, Karsten Spiekermann, MD, Joachim Beck, MD, Wolfram E Jung, MD, Andreas Viardot, Schäfer-Eckart Kerstin, MD, Albrecht Reichle, Sébastien Maury, MD, Norbert Schmitz, MD, Daniela Heidenreich, Jens Panse, MD, Christian Junghanß, MD, Emmanuel Raffoux, MD, Felipe Suarez, MD PhD, Gäelle Guillerm, Magda Alexis, Severine Lissandre, MD, Françoise Huguet, MD, Françoise Isnard, MD, Stephane Lepretre, MD, Martine Escoffre-Barbe, MD, Josep-Maria Ribera, MD PhD, Nicola Goekbuget, MD, Herve Dombret, MD, Dieter Hoelzer, MD, Philippe Rousselot, MD
Journal: Blood
Blood (2014) 124 (21): 798.
https://doi.org/10.1182/blood.V124.21.798.798
Published: 2014
Journal Articles

Significant Improvement Of Outcome In Adolescents and Young adults (AYAs) Aged 15-35 Years With Acute Lymphoblastic Leukemia (ALL) With a Pediatric Derived Adult ALL Protocol; Results Of 1529 AYAs In 2 Consecutive Trials Of The German Multicenter Study Group For Adult ALL (GMALL)

Nicola Gökbuget, MD, Joachim Beck, MD, Kalina Brandt, Monika Brüggemann, MD, Thomas Burmeister, MD, Helmut Diedrich, Christoph Faul, MD, Andreas Hüttmann, Mustafa Kondakci, MD, Doris M Kraemer, M.D., Oliver G. Ottmann, MD, Stefan Schwartz, MD, Hubert Serve, MD, Michael Starck, MD, Matthias Stelljes, MD, Reingard Stuhlmann, MD, Andreas Viardot, Ralph M. Waesch, MD, Knut Wendelin, MD, Dietrich Beelen, MD, Renate Arnold, MD, Dieter Hoelzer, MD
Journal: Blood
Blood (2013) 122 (21): 839.
https://doi.org/10.1182/blood.V122.21.839.839
Published: 2013
Journal Articles

Moderate Intensive Chemotherapy Including CNS-Prophylaxis with Liposomal Cytarabine Is Feasible and effective in Older Patients with Ph-Negative Acute Lymphoblastic Leukemia (ALL): Results of a Prospective Trial From the German Multicenter Study Group for Adult ALL (GMALL)

Nicola Goekbuget, MD, Joachim Beck, MD, Monika Brueggemann, Thomas Burmeister, MD, Eike C. Buss, MD, Norbert Frickhofen, MD, Andreas Huettmann, MD, Anke Morgner, MD, Albrecht Reichle, Ingo Schmidt-Wolf, MD, Stefan Schwartz, MD, Hubert Serve, Prof. Dr. med., Bernd M Spriewald, MD, Michael Starck, MD, Matthias Stelljes, MD, Andreas Viardot, MD, Knut Wendelin, MD, Dieter Hoelzer, MD
Journal: Blood
Blood (2012) 120 (21): 1493.
https://doi.org/10.1182/blood.V120.21.1493.1493
Published: 2012
Journal Articles

Long Term Follow-up of 121 Elderly Patients with Philadelphia-Positive Acute Lymphoblastic Leukaemia (Ph+ALL) Treated in Prospective GMALL Trials Supports a Greater Emphasis On Allogeneic SCT as Definitive Postremission Therapy.

Heike Pfeifer, MD, Christoph Wettner, Barbara Wassmann, Aristoteles A.N. Giagounidis, Matthias Stelljes, MD, Ulrich Duehrsen, MD, Marc Schmalzing, MD, Markus Schaich, MD, Maike De Wit, Arnold Ganser, Winfried Gassmann, MD, PhD, Michael Pfreundschuh, MD, Nicolai Haertel, Knut Wendelin, MD, Mathias Schmid, MD, Hans Joachim Beck, Jolanta Dengler, MD, Heinz-August Horst, MD, Michael Lübbert, MD, Hubert Serve, Prof. Dr. med., Nicola Goekbuget, MD, Dieter Hoelzer, MD, Oliver G. Ottmann, MD
Journal: Blood
Blood (2012) 120 (21): 2608.
https://doi.org/10.1182/blood.V120.21.2608.2608
Published: 2012
Journal Articles

Substantially Improved Outcome of Adult Burkitt Non-Hodgkin Lymphoma and Leukemia Patients with Rituximab and a Short-Intensive Chemotherapy; Report of a Large Prospective Multicenter Trial

Dieter Hoelzer, MD, Jan Walewski, Hartmut Döhner, MD, Mathias Schmid, MD, Wolfgang Hiddemann, MD, PhD, Anja Baumann, MD, Hubert Serve, Prof. Dr. med., Ulrich Dührsen, Andreas Hüttmann, Eckhard Thiel, Jolanta Dengler, MD, Michael Kneba, MD, Markus Schuler, MD, Ingo Schmidt-Wolf, MD, Joachim Beck, MD, Bernd Hertenstein, Albrecht Reichle, Katarzyna Domanska-Czyz, Rainer Fietkau, MD, Heinz-August Horst, MD, Harald Rieder, MD, Stefan Schwartz, MD, Thomas Burmeister, MD, Nicola Goekbuget, MD
Journal: Blood
Blood (2012) 120 (21): 667.
https://doi.org/10.1182/blood.V120.21.667.667
Published: 2012
Journal Articles

Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation

Clinical Trials & Observations
Nicola Gökbuget, Daniel Stanze, Joachim Beck, Helmut Diedrich, Heinz-August Horst, Andreas Hüttmann, Guido Kobbe, Karl-Anton Kreuzer, Lothar Leimer, Albrecht Reichle, Markus Schaich, Stefan Schwartz, Hubert Serve, Michael Starck, Matthias Stelljes, Reingard Stuhlmann, Andreas Viardot, Knut Wendelin, Mathias Freund, Dieter Hoelzer
Journal: Blood
Blood (2012) 120 (10): 2032–2041.
https://doi.org/10.1182/blood-2011-12-399287
Published: 2012
Includes: Supplemental data
Journal Articles

High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation

Clinical Trials & Observations
Nicola Gökbuget, Nadezda Basara, Herrad Baurmann, Joachim Beck, Monika Brüggemann, Helmut Diedrich, Björn Güldenzoph, Gernot Hartung, Heinz-August Horst, Andreas Hüttmann, Guido Kobbe, Ralph Naumann, Richard Ratei, Albrecht Reichle, Hubert Serve, Matthias Stelljes, Andreas Viardot, Mohammed Wattad, Dieter Hoelzer
Journal: Blood
Blood (2011) 118 (13): 3504–3511.
https://doi.org/10.1182/blood-2011-01-329441
Published: 2011
Journal Articles

Long-Term Outcome of 335 Adult Patients Receiving Different Schedules of Imatinib and Chemotherapy as Front-Line Treatment for Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Heike Pfeifer, MD, Nicola Goekbuget, MD, Christian Völp, MD, Andreas Hüttmann, MD, Michael Lübbert, MD, Reingard Stuhlmann, MD, Julanta Dengler, MD, Karl-Anton Kreuzer, MD, Joachim Beck, MD, Matthias Stelljes, MD, Mathias Schmid, MD, B. Wassmann, MD, Lothar Leimer, MD, Karsten Spiekermann, MD, Theis H Terwey, MD, K. Schäfer-Eckart, MD, D. Ditz, MD, H. Lindemann, MD, A. Morgner, MD, Markus Schaich, MD, Thomas Burmeister, MD, A. Binckebanck, Dieter Hoelzer, MD, Oliver G. Ottmann, MD
Journal: Blood
Blood (2010) 116 (21): 173.
https://doi.org/10.1182/blood.V116.21.173.173
Published: 2010
Journal Articles

PEG-Asparaginase Intensification In Adult Acute Lymphoblastic Leukemia (ALL): Significant Improvement of Outcome with Moderate Increase of Liver Toxicity In the German Multicenter Study Group for Adult ALL (GMALL) Study 07/2003

Nicola Goekbuget, MD, Anja Baumann, MD, Joachim Beck, MD, Monika Brueggemann, MD, Helmut Diedrich, MD, Andreas Huettmann, MD, Lothar Leimer, MD, Stefan Zewen, MD, Martin Mohren, MD, Albrecht Reichle, MD, Markus Schaich, MD, Kerstin Schaefer-Eckart, MD, Marc Schmalzing, MD, Mathias Schmid, MD, Hubert Serve, MD, Reingard Stuhlmann, MD, Theis H Terwey, MD, Dieter Hoelzer, MD
Journal: Blood
Blood (2010) 116 (21): 494.
https://doi.org/10.1182/blood.V116.21.494.494
Published: 2010
Journal Articles

Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: results of a multicenter phase 3 study

Clinical Trials & Observations
Bob Löwenberg, Joachim Beck, Carlos Graux, Wim van Putten, Harry C. Schouten, Leo F. Verdonck, Augustin Ferrant, Pieter Sonneveld, Mojca Jongen-Lavrencic, Marie von Lilienfeld-Toal, Bart J. Biemond, Edo Vellenga, Dimitri Breems, Hilde de Muijnck, Ron Schaafsma, Gregor Verhoef, Hartmut Döhner, Alois Gratwohl, Thomas Pabst, Gert J. Ossenkoppele, Johan Maertens, for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON), German Austrian AML Study Group (AMLSG), Swiss Group for Clinical Cancer Research Collaborative Group (SAKK)
Journal: Blood
Blood (2010) 115 (13): 2586–2591.
https://doi.org/10.1182/blood-2009-10-246470
Published: 2010
Journal Articles

Successful Subtype Oriented Treatment Strategies in Adult T-All; Results of 744 Patients Treated in Three Consecutive GMALL Studies.

Dieter Hoelzer, MD, PhD, Eckhard Thiel, Renate Arnold, MD, Joachim Beck, MD, Dietrich W. Beelen, MD, PhD, Martin Bornhäuser, MD, Donald Bunjes, MD, Diana Ditz, MD, Ulrich Dührsen, MD, PhD, Jörg Finke, MD, Heinz A Horst, MD, Guido Kobbe, MD, Hans Jochem Kolb, MD, PhD, Karl Anton Kreuzer, MD, Nicolaus Kröger, MD, Thomas Lipp, MD, Markus Schaich, MD, Mathias Schmid, MD, Stefan Schwartz, MD, Rainer Schwerdtfeger, MD, Hubert Serve, MD, PhD, Reingard Stuhlmann, MD, Knut Wendelin, MD, Christof Scheid, Nicola Gökbuget, MD
Journal: Blood
Blood (2009) 114 (22): 324.
https://doi.org/10.1182/blood.V114.22.324.324
Published: 2009