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Thomas Pabst
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Journal Articles

Ide-cel vs standard regimens in triple-class–exposed relapsed and refractory multiple myeloma: updated KarMMa-3 analyses

Clinical Trials & Observations
Sikander Ailawadhi, Bertrand Arnulf, Krina Patel, Michele Cavo, Ajay K. Nooka, Salomon Manier, Natalie Callander, Luciano J. Costa, Ravi Vij, Nizar J. Bahlis, Philippe Moreau, Scott Solomon, Ingerid Weum Abrahamsen, Rachid Baz, Annemiek Broijl, Christine Chen, Sundar Jagannath, Noopur Raje, Christof Scheid, Michel Delforge, Reuben Benjamin, Thomas Pabst, Shinsuke Iida, Jesús Berdeja, Sergio Giralt, Anna Truppel-Hartmann, Yanping Chen, Xiaobo Zhong, Fan Wu, Julia Piasecki, Laurie Eliason, Devender Dhanda, Jasper Felten, Andrea Caia, Mark Cook, Mihaela Popa McKiver, Paula Rodríguez-Otero
Journal: Blood
Blood (2024) 144 (23): 2389–2401.
https://doi.org/10.1182/blood.2024024582
Published: 2024
Includes: Supplemental data
Journal Articles

Trial in Progress: A Multicenter, Open Label, Randomized, Phase 2 Study of Venetoclax and Azacitidine Plus Cusatuzumab Versus Venetoclax and Azacitidine Alone in Newly Diagnosed AML Patients Who Are Not Candidates for Intensive Therapy

Gail J. Roboz, Ahmed Aribi, Adrian Ochsenbein, Carsten Riether, Monic J. Stuart, Emily Mitchell, Komal Changela, Adam George, Michael Boyiadzis, Clayton Smith, Thomas Pabst
Journal: Blood
Blood (2024) 144 (Supplement 1): 1504.2.
https://doi.org/10.1182/blood-2024-202648
Published: 2024
Journal Articles

Therapy Management and Outcomes in Newly Diagnosed Unfit AML Patients Receiving Venetoclax + HMA - Insights from a Prospective Real-World Study in Switzerland and Austria

Thomas Pabst, Thomas Lehmann, Petra Pichler, Sigrid Machherndl-Spandl, Michael Gregor, Jeroen S. Goede, Sabine Gerull, Daniel Maria Mayer, Jean-François Lambert, Catherine Germanier, Georg Stüssi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2413.
https://doi.org/10.1182/blood-2024-193999
Published: 2024
Journal Articles

Efficacy of Idecabtagene Vicleucel (ide-cel) in Patients with Relapsed/Refractory Multiple Myeloma and Prior Central Nervous System Manifestation: A Retrospective Real-World Analysis

Markus Maulhardt, Philipp Berning, Christine Hanoun, Hristo Boyadzhiev, Anca Maria Albici, Snjezana Janjetovic, Anna Ossami Saidy, Simon Call, Natalie Schub, Enver Aydilek, Michael Daskalakis, Wolfram Jung, Justin Hasenkamp, Carolin Krekeler, Cyrus Khandanpour, Ulrike Bacher, Hans Christian Reinhardt, Georg Lenz, Friedrich Stölzel, Gerald Wulf, Thomas Pabst, Bastian von Tresckow, Evgenii Shumilov
Journal: Blood
Blood (2024) 144 (Supplement 1): 4759.
https://doi.org/10.1182/blood-2024-202467
Published: 2024
Journal Articles

Outcomes of Tagraxofusp in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A Multicenter Real-World Analysis

Philipp Berning, David Baden, Philipp Faustmann, Snjezana Janjetovic, Hanna Katharina Zieger, Jan Christian Schroeder, Giuliano Filippini Velazquez, Anna Ossami Saidy, Hristo Boyadzhiev, Tim Sauer, Jan-Henrik Mikesch, Niklas Gebauer, Susanne Ghandili, Paul J. Bröckelmann, Friederike Hildebrand, Veit L. Buecklein, Rebecca Wurm-Kuczera, Ulrich Keller, Georg Lenz, Thomas Pabst, Thomas Melchardt, Claudia Lengerke, Maher Hanoun, Evgenii Shumilov, Ulrike Bacher
Journal: Blood
Blood (2024) 144 (Supplement 1): 3818.
https://doi.org/10.1182/blood-2024-211227
Published: 2024
Journal Articles

Time of CAR-T Failure Is a Strong Predictor of Outcome for Bispecific Antibody Therapy in Relapsed/Refractory Large B-Cell Lymphoma

Evgenii Shumilov, Rebecca Wurm-Kuczera, Vladan Vucinic, Maximilian Seib, Udo Holtick, Paolo Mazzeo, Julia Katharina Scholz, Hristo Boyadzhiev, Thomas Melchardt, Alexander Hölscher, Christian R Schultze-Florey, Giuliano Filippini Velazquez, Anna Ossami Saidy, Vadim Lesan, Ulf Schnetzke, Andrea Kerkhoff, Ulrike Bacher, Susanne Ghandili, Enver Aydilek, Niklas Gebauer, Thomas Weber, Gerald Wulf, Bertram Glass, Lorenz Thurner, Florian Heidel, Christoph Schmid, Andreas Viardot, Mathias Hänel, Sascha Dietrich, Thomas Pabst, Francis A. Ayuk, Bastian von Tresckow, Björn Chapuy, Christiane Pott, Fabian Mueller, Georg Lenz
Journal: Blood
Blood (2024) 144 (Supplement 1): 114.
https://doi.org/10.1182/blood-2024-198883
Published: 2024
Journal Articles

Real-World Outcomes of CD19-Targeted CAR T-Cell Therapy in Adult and Pediatric Patients with B-Cell Acute Lymphoblastic Leukemia (B-ALL): Insights from the GoCART Coalition on Behalf of the PDWP, ALWP, and CTIWP of the EBMT

Valentin Ortiz-Maldonado, Jacques-Emmanuel Galimard, Giorgio Ottaviano, Anna Alonso-Saladrigues, Shatha Y. Farhan, Sowjanya Vuyyala, Eva Michel, Fizza Imran, Nazaret Sánchez-Sierra, Nuria Martínez-Cibrián, Samppa Ryhänen, Sr., Richard Mitchell, Stephan Mielke, Soeren Lykke Petersen, Anne Sirvent, Thomas Pabst, Jurgen Kuball, Pere Barba, Antonio Perez, Andishe Attarbaschi, Arnon Nagler, Jose Antonio Pérez-Simón, Malte von Bonin, Emma Nicholson, David Beauvais, Julio Delgado, Susana Rives, Krzysztof Kalwak, Fabio Ciceri, Annalisa Ruggeri, Adriana Balduzzi, Sebastian Giebel
Journal: Blood
Blood (2024) 144 (Supplement 1): 2333.
https://doi.org/10.1182/blood-2024-206032
Published: 2024
Journal Articles

MP0533 (CD33 x CD123 x CD70 x CD3), a Tetra-Specific CD3-Engaging Darpin for the Treatment of Patients with Relapsed/Refractory AML or MDS/AML: Results of an Ongoing Phase 1/2a Study

Mojca Jongen-Lavrencic, Thomas Pabst, Pierre Bories, Laimonas Griškevičius, Gerwin Huls, David C. de Leeuw, Steffen Boettcher, Arnaud Pigneux, Nicolas Boissel, Mariola Dymkowska, Christiane Andrieu, Oliver Schönborn-Kellenberger, Paul G. Baverel, Zita Arany, Elena Fernandez, Ana-Maria Florescu, Michael P. Sanderson, Anne Goubier, Vladimir Kirkin, Philippe Legenne, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 2881.
https://doi.org/10.1182/blood-2024-199211
Published: 2024
Journal Articles

Idecabtagene Vicleucel (ide-cel) Shows Similar Efficacy and Toxicity in Patients with Multiple Myeloma Aged 70 and Older Compared to Younger Patients: A Multicenter Cohort Study

Philipp Berning, Markus Maulhardt, Hristo Boyadzhiev, Anca Maria Albici, Snjezana Janjetovic, Anna Ossami Saidy, Christian R Schultze-Florey, Simon Call, Natalie Schub, Annamaria Brioli, Michael Daskalakis, Juliane Knust, Justin Hasenkamp, Matthias Stelljes, Cyrus Khandanpour, Ulrike Bacher, Christine Hanoun, Florian Heidel, Hans Christian Reinhardt, Georg Lenz, Gerald Wulf, Friedrich Stölzel, Bastian von Tresckow, Thomas Pabst, Evgenii Shumilov
Journal: Blood
Blood (2024) 144 (Supplement 1): 3383.
https://doi.org/10.1182/blood-2024-198763
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

Boosting CAR T cells against lymphomas

Thomas Pabst, Ulrike Bacher
Journal: Blood
Blood (2024) 144 (7): 689–691.
https://doi.org/10.1182/blood.2024025378
Published: 2024
Journal Articles

Prognostic Value of Measurable Residual Disease in High-Risk Myelodysplastic Syndromes with Intensive Chemotherapy Treatment: Analysis of HOVON-SAKK Studies

Lok Lam Ngai, Coen R. Veenstra, Patrycja Gradowska, Angèle Kelder, Willemijn Scholten, Alexander N. Snel, Jesse M. Tettero, Costa Bachas, Dimitri Breems, Thomas Fischer, Bjorn T. Gjertsen, Laimonas Griškevičius, Gunnar Juliusson, Johan Maertens, Markus G. Manz, Thomas Pabst, Jakob Passweg, Sr., Kimmo Porkka, Canan Alhan, Theresia M. Westers, Peter J. M. Valk, David C. de Leeuw, Bob Lowenberg, Gert Ossenkoppele, Jacqueline Cloos, Arjan A. van de Loosdrecht
Journal: Blood
Blood (2023) 142 (Supplement 1): 323.
https://doi.org/10.1182/blood-2023-184703
Published: 2023
Journal Articles

A National Platform and Scoring System Allocates CAR-T Treatment Slots for Multiple Myeloma to Patients with High Likelihood of Complete Remission

Christoph Driessen, Katharina Baur, Dominik Heim, Sabine Gerull, Christoph Renner, Anne Cairoli, Thomas Pabst, Joerg Halter, Michael Gregor, Nicole Graf, Nino Fejzibegovic, Nathan Wolfensberger, Federico Simonetta, Martin Fehr, Esteban Ciliberti, Rouven Müller, Barbara Jeker
Journal: Blood
Blood (2023) 142 (Supplement 1): 4701.
https://doi.org/10.1182/blood-2023-182628
Published: 2023
Journal Articles

The Laip-Based-Dfn Approach Is Superior in Terms of Useful MRD Results As Compared to the Laip Approach after Cycle II in Acute Myeloid Leukemia

Lok Lam Ngai, Diana Hanekamp, Angèle Kelder, Willemijn Scholten, Jannemieke Carbaat-Ham, Mona M.H.E Fayed, Alexander N. Snel, Costa Bachas, Jesse M. Tettero, Tim R. Mocking, Vincent H.J. Van Der Velden, Jennichjen Slomp, Willemijn Hobo, Dimitri Breems, Thomas Fischer, Bjorn T. Gjertsen, Laimonas Griškevičius, Gunnar Juliusson, Johan Maertens, Markus G. Manz, Thomas Pabst, Jakob Passweg, Sr., Kimmo Porkka, Peter J. M. Valk, Patrycja Gradowska, Bob Löwenberg, David C. de Leeuw, Arjan A. van de Loosdrecht, Gert Ossenkoppele, Jacqueline Cloos
Journal: Blood
Blood (2023) 142 (Supplement 1): 1572.
https://doi.org/10.1182/blood-2023-181709
Published: 2023
Journal Articles

A Novel Prognostic Model for Patients with Acute Myeloid Leukemia in First Relapse with Improved Prognostic Accuracy

Niek G. Van Der Maas, Dimitri Breems, Clara Klerk, Thomas Pabst, Patrycja Gradowska, Bart J. Biemond, Jurgen Kuball, Janine Van Elssen, Otto Visser, Marie-Christiane Vekemans, Carlos Graux, Johan Maertens, H. Berna Beverloo, Peter J. M. Valk, Gert J. Ossenkoppele, Bob Lowenberg, Geert A. Huls, Jan J. Cornelissen, Jurjen Versluis
Journal: Blood
Blood (2023) 142 (Supplement 1): 724.
https://doi.org/10.1182/blood-2023-180812
Published: 2023
Journal Articles

MP0533, a CD3-Engaging Darpin Targeting CD33, CD123, and CD70 in Patients with Relapsed/Refractory AML or MDS/AML: Preliminary Results of a Phase 1/2a Study

Thomas Pabst, Mojca Jongen-Lavrencic, Steffen Boettcher, Geert A. Huls, David C. de Leeuw, Philippe Legenne, Mariola Dymkowska, Christiane Andrieu, Oliver Schönborn-Kellenberger, Paul G. Baverel, Zita Arany, Elena Fernandez, Anne Goubier, Vladimir Kirkin, Nicolas Leupin, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 2921.
https://doi.org/10.1182/blood-2023-173353
Published: 2023
Journal Articles

Outcome of Intensively Treated Elderly AML Patients Reported to the Harmony Alliance Compares Well to Outcome of Control Patients of the Prospective Randomized HOVON 103 Study in Elderly AML

Sjoerd J.F. Hermans, Jurjen Versluis, Yvette van Norden, Erik D. van Werkhoven, Jeroen J.W.M. Janssen, Gerwin A. Huls, Bob Lowenberg, Thomas Pabst, Dimitri A. Breems, Elizabeth Berkx, Avinash G. Dinmohamed, Peter C. Huijgens, Eric Sträng, Jesús María Hernández-Rivas, Hartmut Döhner, Marta Sobas, Lars Bullinger, Rosa Ayala, Joaquin Martinez-Lopez, Klaus H Metzeler, Torsten Haferlach, Christian Thiede, Carin A. Uyl-De Groot, Gert J. Ossenkoppele, Francesco Pignatti, Jan J. Cornelissen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2854.
https://doi.org/10.1182/blood-2023-186277
Published: 2023
Journal Articles

Idecabtagene Vicleucel (ide-cel) Versus Standard (std) Regimens in Patients (pts) with Triple-Class-Exposed (TCE) Relapsed and Refractory Multiple Myeloma (RRMM): Updated Analysis from KarMMa-3

Paula Rodríguez Otero, Sikander Ailawadhi, Bertrand Arnulf, Krina K. Patel, Michele Cavo, Ajay K. Nooka, Salomon Manier, Natalie S. Callander, Luciano Costa, Ravi Vij, Nizar J Bahlis, Philippe Moreau, Scott R. Solomon, Ingerid Weum Abrahamsen, Rachid Baz, Annemiek Broijl, Christine Chen, Sundar Jagannath, Noopur S. Raje, Christof Scheid, Michel Delforge, Reuben Benjamin, Thomas Pabst, Shinsuke Iida, Jesus G. Berdeja, Anna Truppel-Hartmann, Rashmi Bhatnagar, Fan Wu, Julia Piasecki, Laurie Eliason, Devender Dhanda, Jasper Felten, Andrea Caia, Mark Cook, Mihaela Popa-McKiver, Sergio A. Giralt
Journal: Blood
Blood (2023) 142 (Supplement 1): 1028.
https://doi.org/10.1182/blood-2023-178933
Published: 2023
Journal Articles

Prospective validation of the prognostic relevance of CD34 + CD38 – AML stem cell frequency in the HOVON-SAKK132 trial

Clinical Trials & Observations
Lok Lam Ngai, Diana Hanekamp, Fleur Janssen, Jannemieke Carbaat-Ham, Maaike A. M. A. Hofland, Mona M. H. E Fayed, Angèle Kelder, Laura Oudshoorn-van Marsbergen, Willemijn J. Scholten, Alexander N. Snel, Costa Bachas, Jesse M. Tettero, Dimitri A. Breems, Thomas Fischer, Bjørn T. Gjertsen, Laimonas Griškevičius, Gunnar Juliusson, Arjan A. van de Loosdrecht, Johan A. Maertens, Markus G. Manz, Thomas Pabst, Jakob R. Passweg, Kimmo Porkka, Peter J. M. Valk, Patrycja Gradowska, Bob Löwenberg, David C. de Leeuw, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Jacqueline Cloos
Journal: Blood
Blood (2023) 141 (21): 2657–2661.
https://doi.org/10.1182/blood.2022019160
Published: 2023
Includes: Supplemental data
Journal Articles

Bayesian Inference for Optimization of Interim Analysis in Clinical Trials By Incorporation of Historical Data: Reanalysis of the HOVON AML 132 Clinical Trial

Niek Van Der Maas, Kazem Nasserinejad, Thomas Pabst, Johan A. Maertens, Dimitri A. Breems, Markus G Manz, Jacqueline Cloos, Gert J. Ossenkoppele, Yngvar Floisand, Patrycja Gradowska, Bob Lowenberg, Gerwin A. Huls, Douwe Postmus, Francesco Pignatti, Jan J. Cornelissen, Jurjen Versluis
Journal: Blood
Blood (2022) 140 (Supplement 1): 127–129.
https://doi.org/10.1182/blood-2022-158137
Published: 2022