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Fabian Mueller
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Journal Articles

Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of BMS-986353 (CC-97540), a CD19-Directed Chimeric Antigen Receptor (CAR) T Cell Therapy Manufactured Using a Next-Generation Process, for Severe, Refractory Autoimmune Diseases: Updated Data from Ongoing Phase 1, Multicenter, Open-Label Studies

Fabian Mueller, Krish Patel, Ran Reshef, Mohamad Cherry, Richard Nash, Ernesto Ayala, Jingmei Hsu, Jacques Azzi, Peter Vandenberghe, Roch Houot, Bastian von Tresckow, Giuseppina Stifano, Ashley Koegel, Susana Falcon, Burhan Chaudhry, Lisa Kelly, Jerill Thorpe, Alyse Frisbee, Sam Charab, Sharmila Das, Thomas Ly, Ken Ogasawara, Paolo Caimi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2088.
https://doi.org/10.1182/blood-2024-194525
Published: 2024
Journal Articles

Update on Monocentric CD19-CAR T-Cell Therapy in 30 Patients with Autoimmune Disease

Fabian Mueller, Melanie Hagen, Andreas Wirsching, Soraya Kharboutli, Silvia Spoerl, Carlo Tur, Tobias Krickau, Laura Bucci, Christina Bergmann, Janina Auth, Panayiotis Garantziotis, Sebastian Boeltz, Sascha Kretschmann, Ingrid Vasova, Dimitrios Mougiakakos, Michael Aigner, Ricardo Grieshaber-Bouyer, Markus Metzler, Simon Voelkl, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2024) 144 (Supplement 1): 684.
https://doi.org/10.1182/blood-2024-206163
Published: 2024
Journal Articles

Inflammation-Based Scores Predict Survival after CD3xCD20 Bispecific T Cell Engagers in R/R LBCL

Giulia Magno, Kai Rejeski, Giulia Rappa, Sissi Kupf, Sophia Stock, Alessandra M. E. Holzem, Julia Katharina Scholz, Rebecca Wurm-Kuczera, Shimrit Harlev, Nadine Kutsch, Giuliano Filippini Velazquez, Stephanie Mayer, Maria Landwehr, Jamila Mammadova, Sandeep S. Raj, Roni Shouval, Fabian Mueller, Björn Chapuy, Ofrat Beyar-Katz, Udo Holtick, Christoph Schmidt, Hendrik Poeck, Gloria Iacoboni, Pere Barba, Ning Dong, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 1714.
https://doi.org/10.1182/blood-2024-211459
Published: 2024
Journal Articles

Distinct Safety and Toxicity Profile of CD19-Directed CAR T-Cell Therapy in Systemic Lupus Erythematosus Versus B-Cell Lymphoma - a Single-Center Experience

Nora Rebecca Schwingen, Fabian Mueller, Julia Katharina Scholz, Michael Aigner, Melanie Hagen, Andreas Wirsching, Jule Taubmann, Sascha Kretschmann, Soraya Kharboutli, Tobias Krickau, Nora Naumann-Bartsch, Giulia Benintende, Silvia Spoerl, Ingrid Vasova, Tobias Rothe, Heiko Bruns, Ricardo Grieshaber-Bouyer, Frederik Graw, Markus Metzler, Georg Schett, Andreas Mackensen, Simon Voelkl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4835.
https://doi.org/10.1182/blood-2024-207051
Published: 2024
Journal Articles

Efficacy of Anti-BCMA CAR-T Cell Therapies in Multiple Myeloma Patients with Prior Exposure to Bispecific Antibodies- Results from a Retrospective Multi-Center Registry Analysis

Johannes Waldschmidt, David Fandrei, Vladan Vucinic, Ralph Wäsch, Axel Nogai, Winfried Alsdorf, Annamaria Brioli, Evgenii Shumilov, Fabian Mueller, Raphael Teipel, Nico Gagelmann, Monika Engelhardt, Jan Krönke, Julia Mersi, Michael Hudecek, Martin K. Kortüm, Uwe Platzbecker, Hermann Einsele, Max S. Topp, Leo Rasche, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2024-210451
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

Time of CAR-T Failure Is a Strong Predictor of Outcome for Bispecific Antibody Therapy in Relapsed/Refractory Large B-Cell Lymphoma

Evgenii Shumilov, Rebecca Wurm-Kuczera, Vladan Vucinic, Maximilian Seib, Udo Holtick, Paolo Mazzeo, Julia Katharina Scholz, Hristo Boyadzhiev, Thomas Melchardt, Alexander Hölscher, Christian R Schultze-Florey, Giuliano Filippini Velazquez, Anna Ossami Saidy, Vadim Lesan, Ulf Schnetzke, Andrea Kerkhoff, Ulrike Bacher, Susanne Ghandili, Enver Aydilek, Niklas Gebauer, Thomas Weber, Gerald Wulf, Bertram Glass, Lorenz Thurner, Florian Heidel, Christoph Schmid, Andreas Viardot, Mathias Hänel, Sascha Dietrich, Thomas Pabst, Francis A. Ayuk, Bastian von Tresckow, Björn Chapuy, Christiane Pott, Fabian Mueller, Georg Lenz
Journal: Blood
Blood (2024) 144 (Supplement 1): 114.
https://doi.org/10.1182/blood-2024-198883
Published: 2024
Journal Articles

Applying the Novel EHA/EBMT Grading System for Icaht Following CAR-T Therapy: Comparative Incidence across Disease Entities and Association with Infections and Mortality

Kai Rejeski, Doris K. Hansen, Yucai Wang, Gloria Iacoboni, Emmanuel Bachy, Radhika Bansal, Olaf Penack, Fabian Mueller, Wolfgang Andreas Bethge, Javier L. Munoz, Razan Mohty, Veit L. Buecklein, Pere Barba, Frederick L. Locke, Yi Lin, Michael D. Jain, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 359.
https://doi.org/10.1182/blood-2023-180607
Published: 2023
Journal Articles

Multinational Retrospective Analysis of Bridging Therapy Prior to Chimeric Antigen Receptor T Cells for Relapsed/Refractory Acute Lymphoblastic Leukemia in Children and Young Adults

Maike Breidenbach, Peter Bader, Andishe Attarbaschi, Claudia Rossig, Roland Meisel, Markus Metzler, Marion Subklewe, Fabian Mueller, Paul-Gerhardt Schlegel, Irene Teichert von Lüttichau, Jean-Pierre Bourquin, Gabriele Escherich, Gunnar Cario, Peter Lang, Ramona Krauss, Arend von Stackelberg, Semjon Willier, Christina Peters, Tobias Feuchtinger
Journal: Blood
Blood (2023) 142 (Supplement 1): 2135.
https://doi.org/10.1182/blood-2023-190117
Published: 2023
Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Autoimmune Diseases: A Monocentric Experience from the First Fifteen Patients

Fabian Mueller, Jule Taubmann, Simon Voelkl, Laura Bucci, Christina Bergmann, Michael Aigner, Artur Wilhelm, Tobias Rothe, Ioanna Minopoulou, Johannes Knitza, Soraya Kharboutli, Silvia Spoerl, Ingrid Vasova, Dagmar Werner, Hannah Reimann, Sascha Kretschmann, Dimitrios Mougiakakos, Gerhard Krönke, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2023) 142 (Supplement 1): 220.
https://doi.org/10.1182/blood-2023-180547
Published: 2023
Journal Articles

Real World Results of Brexucabtagene Autoleucel for Patients with Relapsed/Refractory Mantle Cell Lymphoma - First German/Swiss Analysis

Georg Hess, Vladan Vucinic, Kai Rejeski, Enver Aydilek, Linda Simon, Olaf Penack, Christian Koenecke, Malte von Bonin, Bastian von Tresckow, Martin Fehr, Christiane Pott, Stephan Stilgenbauer, Corinna Leng, Roland Schroers, Johannes Duell, Reinhard Marks, Fabian Mueller, Uta Brunnberg, Andrea Kerkhoff, Anke Ohler, Eva-Maria Wagner Drouet, Irene Schmidtmann, Matthias Theobald, Martin Dreyling, Peter Dreger
Journal: Blood
Blood (2023) 142 (Supplement 1): 4394.
https://doi.org/10.1182/blood-2023-182415
Published: 2023
Journal Articles

Impact of Sex on Clinical Outcomes after CD19 CAR T-Cell Therapy for Large B-Cell Lymphoma: Response and Survival Are Significantly Superior in Female Compared to Male Patients

Veit L. Buecklein, Kai Rejeski, Ariel Perez, Gloria Iacoboni, Vindi Jurinovic, Soraya Kharboutli, Viktoria Blumenberg, Josephine Ackermann, Lisa Frölich, Grace Johnson, Kedar Patel, Brian Arciola, Rahul Mhaskar, Christian Schmidt, Anthony Wood, Eva Hoster, Andreas Mackensen, Frederick L. Locke, Michael von Bergwelt-Baildon, Fabian Mueller, Pere Barba, Michael D. Jain, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3787.
https://doi.org/10.1182/blood-2023-186510
Published: 2023
Journal Articles

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Fabian Mueller, Nora Rebecca Schwingen, Lena Stabel, Michael Aigner, Jule Taubmann, Sascha Kretschmann, Hannah Reimann, Gloria Lutzny-Geier, Michael Schletter, Nina Eisenhauer, Soraya Kharboutli, Artur Wilhelm, Tobias Rothe, Dagmar Werner, Julio Vera Gonzalez, Ioanna Minopoulou, Christina Bergmann, Heiko Bruns, Gerhard Krönke, Frederik Graw, Georg Schett, Andreas Mackensen, Simon Voelkl
Journal: Blood
Blood (2023) 142 (Supplement 1): 6871.
https://doi.org/10.1182/blood-2023-188830
Published: 2023
Journal Articles

Nex-T TM Cluster of Differentiation 19 (CD19) Chimeric Antigen Receptor (CAR) T-Cell Therapy BMS-986353 (CC-97540): Comparative Analysis of Baseline Patient Data from Trials in Systemic Lupus Erythematosus (SLE) and Relapsed/Refractory Large B-Cell Lymphoma (R/R LBCL) Related to Manufacturability and Potential Safety

Fabian Mueller, Julie Rytlewski, Chun Wu, Sarah Hu, Ashley Koegel, Nikolay Delev, Ana Kostic, Vaishali Shah, Thomas Wegman, Georg Schett
Journal: Blood
Blood (2023) 142 (Supplement 1): 6873.
https://doi.org/10.1182/blood-2023-174276
Published: 2023
Journal Articles

Tafasitamab and Lenalidomide in Relapsed/Refractory B-Cell Lymphoma: A Multicenter Retrospective Real-World-Study of Patients from Germany and Austria

Anna Ruckdeschel, Koemm Sabrina, Max S. Topp, Richard Greil, Thomas Melchardt, Georg Lenz, Andrea Kerkhoff, Evgenii Shumilov, Georg Hess, Marta Baumgaertner, Lorenz Thurner, Igor Age Kos, Stephanie Mayer, Francis A. Ayuk, Rolf Krause, Marco Herling, Vladan Vucinic, Claudia Chapuy, Gerald Illerhaus, Markus Knott, Andreas Viardot, Alexander Grunenberg, Sascha Dietrich, Leandra Caille, Mareike C. Tometten, Hyunyee Rosa Cho, Julia Scholz, Fabian Mueller, Katharina Prochazka, Bjoern Chapuy, David Böckle, Bastian von Tresckow, Natalie Schub, Götz Gelbrich, Hermann Einsele, Johannes Duell
Journal: Blood
Blood (2023) 142 (Supplement 1): 1771.
https://doi.org/10.1182/blood-2023-185992
Published: 2023
Journal Articles

CD19-CAR-T Cells Are Effective and Safe Treatment of Post-Transplant Relapse in Pediatric and Young Adult Patients with B-Lineage ALL: Real-World Data from Germany

Peter Bader, Claudia Rossig, Martin Hutter, Francis A. Ayuk, Claudia D. Baldus, Veit L Buecklein, Halvard Bonig, Gunnar Cario, Hermann Einsele, Udo Holtick, Christian Koenecke, Annette Künkele, Roland Meisel, Fabian Mueller, Ingo Müller, Olaf Penack, Eva Rettinger, Martin G. Sauer, Paul-Gerhardt Schlegel, Jan Soerensen, Arend von Stackelberg, Tobias Feuchtinger, Andrea Jarisch
Journal: Blood
Blood (2022) 140 (Supplement 1): 10407–10409.
https://doi.org/10.1182/blood-2022-156775
Published: 2022
Journal Articles

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

Hannah Reimann, Anita Natalie Kremer, Viktoria Blumenberg, Katja Schmidt, Michael Aigner, Andreas Kremer, Matthias Tenbusch, Heiko Bruns, Thomas Harrer, Georg Schett, Fabian Mueller, Andreas Mackensen, Marion Subklewe, Simon Voelkl
Journal: Blood
Blood (2022) 140 (Supplement 1): 10279–10280.
https://doi.org/10.1182/blood-2022-165968
Published: 2022
Journal Articles

Block of Counter-Regulation By Inhibition of Protein Synthesis Sensitizes Cancer Cells to IRE1α-Mediated Apoptosis Following Unfolded Protein Response

Franziska Gsottberger, Christina Meier, Anna Ammon, Scott Parker, Kerstin Wendland, Rebekka George, Srdjan Petkovic, Lisa Mellenthin, Charlotte Emmerich, Gloria Lutzny-Geier, Markus Metzler, Andreas Mackensen, Vidyalakshmi Chandramohan, Fabian Mueller
Journal: Blood
Blood (2022) 140 (Supplement 1): 3122.
https://doi.org/10.1182/blood-2022-169012
Published: 2022
Journal Articles

Early Real Time Quantification of CD19. CAR T Cells By Flow Cytometry As a Predictive Biomarker for Response in Patients with R/R LBCL

Viktoria Blumenberg, Galina Busch, Stephan Baumann, Regina Jitschin, Michael Winkelmann, Konstantin Hellwig, Kai Rejeski, Lisa Frölich, Benjamin Tast, Christian Schmidt, Friederike Hildebrandt, Franziska Dekorsy, Christian Schmidkonz, Tobias Bäuerle, Wolfgang G. Kunz, Fabian Mueller, Dimitrios Mougiakakos, Michael von Bergwelt, Veit Bücklein, Andreas Mackensen, Simon Voelkl, Marion Subklewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 7522–7523.
https://doi.org/10.1182/blood-2022-168874
Published: 2022
Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Lupus Erythematosus: Safety, Efficacy, and Mechanistic Insights from the First Five Patients

Fabian Mueller, Simon Voelkl, Dimitrios Mougiakakos, Sebastian Boeltz, Michael Aigner, Regina Gary, Sascha Kretschmann, Soraya Kharboutli, Arnd Kleyer, David Simon, Wolf Rösler, Katharina M. Habenicht, Thomas H. Winkler, Gerhard Krönke, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2022) 140 (Supplement 1): 4562–4563.
https://doi.org/10.1182/blood-2022-165077
Published: 2022