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Journal Articles

Update on Monocentric CD19-CAR T-Cell Therapy in 30 Patients with Autoimmune Disease

Blood (2024) 144 (Supplement 1): 684.

https://doi.org/10.1182/blood-2024-206163

Published: 2024

Journal Articles

Distinct Safety and Toxicity Profile of CD19-Directed CAR T-Cell Therapy in Systemic Lupus Erythematosus Versus B-Cell Lymphoma - a Single-Center Experience

Blood (2024) 144 (Supplement 1): 4835.

https://doi.org/10.1182/blood-2024-207051

Published: 2024

Journal Articles

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Blood (2023) 142 (Supplement 1): 6871.

https://doi.org/10.1182/blood-2023-188830

Published: 2023

Journal Articles

Prevention of CMV/EBV Reactivation By Double-Specific T Cells in Patients after Allogeneic Stem Cell Transplantation: Results from the Randomized Phase I/IIa Multivir-01 Study

Blood (2023) 142 (Supplement 1): 6849.

https://doi.org/10.1182/blood-2023-178273

Published: 2023

Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Autoimmune Diseases: A Monocentric Experience from the First Fifteen Patients

Blood (2023) 142 (Supplement 1): 220.

https://doi.org/10.1182/blood-2023-180547

Published: 2023

Journal Articles

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

Hannah Reimann, Anita Natalie Kremer, Viktoria Blumenberg, Katja Schmidt, Michael Aigner, Andreas Kremer, Matthias Tenbusch, Heiko Bruns, Thomas Harrer, Georg Schett, Fabian Mueller, Andreas Mackensen, Marion Subklewe, Simon Voelkl

Blood (2022) 140 (Supplement 1): 10279–10280.

https://doi.org/10.1182/blood-2022-165968

Published: 2022

Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Lupus Erythematosus: Safety, Efficacy, and Mechanistic Insights from the First Five Patients

Fabian Mueller, Simon Voelkl, Dimitrios Mougiakakos, Sebastian Boeltz, Michael Aigner, Regina Gary, Sascha Kretschmann, Soraya Kharboutli, Arnd Kleyer, David Simon, Wolf Rösler, Katharina M. Habenicht, Thomas H. Winkler, Gerhard Krönke, Georg Schett, Andreas Mackensen

Blood (2022) 140 (Supplement 1): 4562–4563.

https://doi.org/10.1182/blood-2022-165077

Published: 2022

Journal Articles

Detection of Signature Double-Negative T Cells Is a Reliable Marker for ALPS Associated with FAS Mutation

Nina Eisenhauer, Maurizio Miano, Nora Naumann-Bartsch, Joerg Leyh, Paola Terranova, Claas Hinze, Michael Aigner, Helmut Wittkowski, Heiko Bruns, Stephan Ehl, Markus Metzler, Peter Arkwright, Andreas Mackensen, Anne Rensing-Ehl, Simon Voelkl

Blood (2022) 140 (Supplement 1): 11194.

https://doi.org/10.1182/blood-2022-168550

Published: 2022

Journal Articles

A Phase I Open Label Dose Escalation Study of MB-CART19.1 in Relapsed and Refractory CD19+ B Cell Malignancies, Interim Preliminary Results in Pediatric ALL, Adult ALL Including CLL Cohorts

Andreas Mackensen, Linda Hanssens, Matthias Stelljes, Wolfgang A Bethge, Tobias Feuchtinger, Annette Künkele, Michael Aigner, Alisa Yakushina, Sandra Karitzky, Silke Holtkamp, Mario Assenmacher, Marion Jurk, Georg Rauser, Dina Schneider, Claudia Rossig

Blood (2021) 138 (Supplement 1): 3836.

https://doi.org/10.1182/blood-2021-152452

Published: 2021

Journal Articles

Effect of Proinflammatory and Homeostatic Cytokines on the Functionality of Human Double-Negative Regulatory T Cells

Moritz Peuser, Tabea Haug, Michael Aigner, PhD, Andreas Mackensen, MD, Simon Voelkl

Blood (2018) 132 (Supplement 1): 3726.

https://doi.org/10.1182/blood-2018-99-112977

Published: 2018

Journal Articles

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Tabea Haug, Michael Aigner, PhD, Heiko Bruns, PhD, Moritz Peuser, Dorothea Gebhardt, Jana Berger, Florentine Koppitz, Andreas Mackensen, MD, Simon Voelkl

Blood (2018) 132 (Supplement 1): 2410.

https://doi.org/10.1182/blood-2018-99-112943

Published: 2018

Journal Articles

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, PhD, Andreas Mackensen, MD, Simon Voelkl, PhD

Blood (2017) 130 (Supplement 1): 3579.

https://doi.org/10.1182/blood.V130.Suppl_1.3579.3579

Published: 2017

Journal Articles

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, Andreas Mackensen, Simon Voelkl, PhD

Blood (2016) 128 (22): 3694.

https://doi.org/10.1182/blood.V128.22.3694.3694

Published: 2016

Journal Articles

Adoptive Transfer of CMV- and EBV- Specific Peptide-Stimulated T Cells after Allogeneic Stem Cell Transplantation: First Results of a Phase I/IIa Clinical Trial [Multivir-01]

Regina Gary, Michael Aigner, Andreas Moosmann, Julia Ritter, Volkhard Seitz, Stephanie Moi, Stefanie Schaffer, Heidi Balzer, Stefanie Maas, MD, Julian Strobel, MD, Robert Zimmermann, Juergen Zingsem, Anita Kremer, Steffen Hennig, Michael Hummel, Andreas Mackensen, Armin Gerbitz

Blood (2016) 128 (22): 2179.

https://doi.org/10.1182/blood.V128.22.2179.2179

Published: 2016

Journal Articles

Activity Of Single Agent Temsirolimus and Associated Impact On Bone Marrow Vascularization and T-Cell Composition In Patients With Myelodysplastic Syndromes – Result Of The Prospective Temds Trial Of The German MDS-SG

Martin Wermke, MD, Claudia Schuster, Claudia Schönefeldt, Christiane Jakob, MD, Malte von Bonin, MD, Florian Nolte, MD, Philipp Kiewe, MD, Regina Herbst, MD, Ulrich Germing, MD, Michael Aigner, PhD, Detlef Haase, MD, Ina-Maria Klut, PhD, Nadja Jaekel, Gustavo Baretton, MD, Martin Bornhäuser, MD, Gerhard Ehninger, MD, Wolf-Karsten Hofmann, MD, Uwe Platzbecker, MD, PhD

Blood (2013) 122 (21): 2808.

https://doi.org/10.1182/blood.V122.21.2808.2808

Published: 2013

Journal Articles

Autologous T Cells From AML Patients Can Be Effectively Recruited for In-Vitro Lysis of Blasts by a Novel CD33/CD3-Bispecific BiTE Antibody

Michael Aigner, PhD, Julian Feulner, Roman Kischel, MD, Peter Kufer, MD, Patrick A Baeuerle, PhD, Andreas Mackensen, MD, Stefan W. Krause, MD

Blood (2010) 116 (21): 14.

https://doi.org/10.1182/blood.V116.21.14.14

Published: 2010

NARROW

Update on Monocentric CD19-CAR T-Cell Therapy in 30 Patients with Autoimmune Disease

Distinct Safety and Toxicity Profile of CD19-Directed CAR T-Cell Therapy in Systemic Lupus Erythematosus Versus B-Cell Lymphoma - a Single-Center Experience

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Prevention of CMV/EBV Reactivation By Double-Specific T Cells in Patients after Allogeneic Stem Cell Transplantation: Results from the Randomized Phase I/IIa Multivir-01 Study

CD19-Targeted CAR-T Cells in Refractory Systemic Autoimmune Diseases: A Monocentric Experience from the First Fifteen Patients

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

CD19-Targeted CAR-T Cells in Refractory Systemic Lupus Erythematosus: Safety, Efficacy, and Mechanistic Insights from the First Five Patients

Detection of Signature Double-Negative T Cells Is a Reliable Marker for ALPS Associated with FAS Mutation

A Phase I Open Label Dose Escalation Study of MB-CART19.1 in Relapsed and Refractory CD19+ B Cell Malignancies, Interim Preliminary Results in Pediatric ALL, Adult ALL Including CLL Cohorts

Effect of Proinflammatory and Homeostatic Cytokines on the Functionality of Human Double-Negative Regulatory T Cells

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Adoptive Transfer of CMV- and EBV- Specific Peptide-Stimulated T Cells after Allogeneic Stem Cell Transplantation: First Results of a Phase I/IIa Clinical Trial [Multivir-01]

Activity Of Single Agent Temsirolimus and Associated Impact On Bone Marrow Vascularization and T-Cell Composition In Patients With Myelodysplastic Syndromes – Result Of The Prospective Temds Trial Of The German MDS-SG

Autologous T Cells From AML Patients Can Be Effectively Recruited for In-Vitro Lysis of Blasts by a Novel CD33/CD3-Bispecific BiTE Antibody

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American Society of Hematology

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American Society of Hematology

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