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Journal Articles

CAR T-cells in autoimmunity: game changer or stepping stone?

Dimitrios Mougiakakos, Everett Meyer, Georg Schett
Journal: Blood
Blood blood.2024025413.
https://doi.org/10.1182/blood.2024025413
Published: 2024
Includes: Supplemental data
Journal Articles

Update on Monocentric CD19-CAR T-Cell Therapy in 30 Patients with Autoimmune Disease

Fabian Mueller, Melanie Hagen, Andreas Wirsching, Soraya Kharboutli, Silvia Spoerl, Carlo Tur, Tobias Krickau, Laura Bucci, Christina Bergmann, Janina Auth, Panayiotis Garantziotis, Sebastian Boeltz, Sascha Kretschmann, Ingrid Vasova, Dimitrios Mougiakakos, Michael Aigner, Ricardo Grieshaber-Bouyer, Markus Metzler, Simon Voelkl, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2024) 144 (Supplement 1): 684.
https://doi.org/10.1182/blood-2024-206163
Published: 2024
Journal Articles

Distinct Safety and Toxicity Profile of CD19-Directed CAR T-Cell Therapy in Systemic Lupus Erythematosus Versus B-Cell Lymphoma - a Single-Center Experience

Nora Rebecca Schwingen, Fabian Mueller, Julia Katharina Scholz, Michael Aigner, Melanie Hagen, Andreas Wirsching, Jule Taubmann, Sascha Kretschmann, Soraya Kharboutli, Tobias Krickau, Nora Naumann-Bartsch, Giulia Benintende, Silvia Spoerl, Ingrid Vasova, Tobias Rothe, Heiko Bruns, Ricardo Grieshaber-Bouyer, Frederik Graw, Markus Metzler, Georg Schett, Andreas Mackensen, Simon Voelkl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4835.
https://doi.org/10.1182/blood-2024-207051
Published: 2024
Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Autoimmune Diseases: A Monocentric Experience from the First Fifteen Patients

Fabian Mueller, Jule Taubmann, Simon Voelkl, Laura Bucci, Christina Bergmann, Michael Aigner, Artur Wilhelm, Tobias Rothe, Ioanna Minopoulou, Johannes Knitza, Soraya Kharboutli, Silvia Spoerl, Ingrid Vasova, Dagmar Werner, Hannah Reimann, Sascha Kretschmann, Dimitrios Mougiakakos, Gerhard Krönke, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2023) 142 (Supplement 1): 220.
https://doi.org/10.1182/blood-2023-180547
Published: 2023
Journal Articles

CAR-T Cell Therapy in Patients with Refractory Systemic Autoimmune Diseases Exhibits Less Inflammation, Toxicities and Different Cellular Dynamics Compared to Patients with B Cell Lymphoma

Fabian Mueller, Nora Rebecca Schwingen, Lena Stabel, Michael Aigner, Jule Taubmann, Sascha Kretschmann, Hannah Reimann, Gloria Lutzny-Geier, Michael Schletter, Nina Eisenhauer, Soraya Kharboutli, Artur Wilhelm, Tobias Rothe, Dagmar Werner, Julio Vera Gonzalez, Ioanna Minopoulou, Christina Bergmann, Heiko Bruns, Gerhard Krönke, Frederik Graw, Georg Schett, Andreas Mackensen, Simon Voelkl
Journal: Blood
Blood (2023) 142 (Supplement 1): 6871.
https://doi.org/10.1182/blood-2023-188830
Published: 2023
Journal Articles

Nex-T TM Cluster of Differentiation 19 (CD19) Chimeric Antigen Receptor (CAR) T-Cell Therapy BMS-986353 (CC-97540): Comparative Analysis of Baseline Patient Data from Trials in Systemic Lupus Erythematosus (SLE) and Relapsed/Refractory Large B-Cell Lymphoma (R/R LBCL) Related to Manufacturability and Potential Safety

Fabian Mueller, Julie Rytlewski, Chun Wu, Sarah Hu, Ashley Koegel, Nikolay Delev, Ana Kostic, Vaishali Shah, Thomas Wegman, Georg Schett
Journal: Blood
Blood (2023) 142 (Supplement 1): 6873.
https://doi.org/10.1182/blood-2023-174276
Published: 2023
Journal Articles

Sars-Cov-2 Vaccine-Induced Cellular and Humoral Immunity in Patients after CD19.CAR-T Cell Therapy

Hannah Reimann, Anita Natalie Kremer, Viktoria Blumenberg, Katja Schmidt, Michael Aigner, Andreas Kremer, Matthias Tenbusch, Heiko Bruns, Thomas Harrer, Georg Schett, Fabian Mueller, Andreas Mackensen, Marion Subklewe, Simon Voelkl
Journal: Blood
Blood (2022) 140 (Supplement 1): 10279–10280.
https://doi.org/10.1182/blood-2022-165968
Published: 2022
Journal Articles

CD19-Targeted CAR-T Cells in Refractory Systemic Lupus Erythematosus: Safety, Efficacy, and Mechanistic Insights from the First Five Patients

Fabian Mueller, Simon Voelkl, Dimitrios Mougiakakos, Sebastian Boeltz, Michael Aigner, Regina Gary, Sascha Kretschmann, Soraya Kharboutli, Arnd Kleyer, David Simon, Wolf Rösler, Katharina M. Habenicht, Thomas H. Winkler, Gerhard Krönke, Georg Schett, Andreas Mackensen
Journal: Blood
Blood (2022) 140 (Supplement 1): 4562–4563.
https://doi.org/10.1182/blood-2022-165077
Published: 2022
Journal Articles

Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease

Yun Zhang, Lichong Shen, Katja Dreißigacker, Honglin Zhu, Thuong Trinh-Minh, Xianyi Meng, Cuong Tran-Manh, Clara Dees, Alexandru-Emil Matei, Chih-Wei Chen, Markus Ditschkowski, Stefan Krauss, Julia Winkler, Daniel Wolff, Mirjana Ziemer, Andreas Beilhack, Sigrid Karrer, Wolfgang Herr, Andreas Mackensen, Georg Schett, Bernd M. Spriewald, Jörg H. W. Distler
Journal: Blood
Blood (2021) 137 (17): 2403–2416.
https://doi.org/10.1182/blood.2020008720
Published: 2021
Includes: Supplemental data
Journal Articles

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease

Pawel Zerr, Katrin Palumbo-Zerr, Alfiya Distler, Michal Tomcik, Stefan Vollath, Luis E. Munoz, Christian Beyer, Clara Dees, Friederike Egberts, Ilaria Tinazzi, Francesco Del Galdo, Oliver Distler, Georg Schett, Bernd M. Spriewald, Jörg H. W. Distler
Journal: Blood
Blood (2012) 120 (14): 2909–2917.
https://doi.org/10.1182/blood-2012-01-403428
Published: 2012
Journal Articles

Novel Anti-Fibrotic Therapies for Experimental Chronic Graft-Versus-Host Disease.

Bernd M. Spriewald, MD, Pawel Zerr, MSc, Alfiya Akhmetshina, PhD, Andreas Mackensen, MD, Georg Schett, MD, Joerg H.W. Distler, MD
Journal: Blood
Blood (2009) 114 (22): 4490.
https://doi.org/10.1182/blood.V114.22.4490.4490
Published: 2009