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Journal Articles

Inflammation-Based Scores Predict Survival after CD3xCD20 Bispecific T Cell Engagers in R/R LBCL

Giulia Magno, Kai Rejeski, Giulia Rappa, Sissi Kupf, Sophia Stock, Alessandra M. E. Holzem, Julia Katharina Scholz, Rebecca Wurm-Kuczera, Shimrit Harlev, Nadine Kutsch, Giuliano Filippini Velazquez, Stephanie Mayer, Maria Landwehr, Jamila Mammadova, Sandeep S. Raj, Roni Shouval, Fabian Mueller, Björn Chapuy, Ofrat Beyar-Katz, Udo Holtick, Christoph Schmidt, Hendrik Poeck, Gloria Iacoboni, Pere Barba, Ning Dong, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 1714.
https://doi.org/10.1182/blood-2024-211459
Published: 2024
Journal Articles

Time of CAR-T Failure Is a Strong Predictor of Outcome for Bispecific Antibody Therapy in Relapsed/Refractory Large B-Cell Lymphoma

Evgenii Shumilov, Rebecca Wurm-Kuczera, Vladan Vucinic, Maximilian Seib, Udo Holtick, Paolo Mazzeo, Julia Katharina Scholz, Hristo Boyadzhiev, Thomas Melchardt, Alexander Hölscher, Christian R Schultze-Florey, Giuliano Filippini Velazquez, Anna Ossami Saidy, Vadim Lesan, Ulf Schnetzke, Andrea Kerkhoff, Ulrike Bacher, Susanne Ghandili, Enver Aydilek, Niklas Gebauer, Thomas Weber, Gerald Wulf, Bertram Glass, Lorenz Thurner, Florian Heidel, Christoph Schmid, Andreas Viardot, Mathias Hänel, Sascha Dietrich, Thomas Pabst, Francis A. Ayuk, Bastian von Tresckow, Björn Chapuy, Christiane Pott, Fabian Mueller, Georg Lenz
Journal: Blood
Blood (2024) 144 (Supplement 1): 114.
https://doi.org/10.1182/blood-2024-198883
Published: 2024
Journal Articles

Impact of Allogeneic Hematopoietic Cell Transplantation Post-Sars-Cov-2 Infection: A Retrospective Analysis By the German Cooperative Transplant Study Group

Osama Ahmad, Jan Frederic Weller, Nicolaus Kröger, Eva Wagner Drouet, David Nachbaur, Normann Steiner, Daniel Teschner, Sabrina Kraus, Gesine Bug, Salem Ajib, Johannes Schetelig, Wolfgang Andreas Bethge, Thomas Schroeder, Judith Schaffrath, Lutz Peter Hermann Mueller, Mareike Verbeek, Edgar Jost, Hatice Soysal, Georg-Nikolaus Franke, Stefan Klein, Udo Holtick, Knut Wendelin, Claudia Lengerke, Martin Bornhäuser, Maximilian Christopeit
Journal: Blood
Blood (2024) 144 (Supplement 1): 3554.
https://doi.org/10.1182/blood-2024-204560
Published: 2024
Journal Articles

Desiccation Stress Triggers and Exacerbates Experimental Ocular Graft-Versus-Host-Disease

Philipp Steven, Uta Gehlsen, Martina Maass, Manolis Pasparakis, Cintia S. de Paiva, Udo Holtick, Christof Scheid, Michael E. Stern
Journal: Blood
Blood (2024) 144 (Supplement 1): 7105.
https://doi.org/10.1182/blood-2024-206001
Published: 2024
Journal Articles

Hope for motherhood: pregnancy after allogeneic hematopoietic cell transplantation (a national multicenter study)

Clinical Trials & Observations
Katja Sockel, Annika Neu, Maren Goeckenjan, Markus Ditschkowski, Inken Hilgendorf, Nicolaus Kröger, Francis A. Ayuk, Friedrich Stoelzel, Jan Moritz Middeke, Matthias Eder, Wolfgang Bethge, Jürgen Finke, Hartmut Bertz, Guido Kobbe, Martin Kaufmann, Uwe Platzbecker, David Beverungen, Christoph Schmid, Malte von Bonin, Katharina Egger-Heidrich, Lisa Heberling, Karolin Trautmann-Grill, Raphael Teipel, Gesine Bug, Johanna Tischer, Alessia Fraccaroli, Matthias Fante, Daniel Wolff, Thomas Luft, Julia Winkler, Kerstin Schäfer-Eckart, Christof Scheid, Udo Holtick, Stefan Klein, Igor Wolfgang Blau, Andreas Burchert, Gerald Wulf, Justin Hasenkamp, Rainer Schwerdtfeger, Stephan Kaun, Christian Junghanss, Friederike Wortmann, Susann Winter, Helga Neidlinger, Catrin Theuser, Jan Beyersmann, Martin Bornhaeuser, Sandra Schmeller, Johannes Schetelig
Journal: Blood
Blood (2024) 144 (14): 1532–1542.
https://doi.org/10.1182/blood.2024024342
Published: 2024
Includes: Supplemental data
Journal Articles

CD19-CAR-T Cells Are Effective and Safe Treatment of Post-Transplant Relapse in Pediatric and Young Adult Patients with B-Lineage ALL: Real-World Data from Germany

Peter Bader, Claudia Rossig, Martin Hutter, Francis A. Ayuk, Claudia D. Baldus, Veit L Buecklein, Halvard Bonig, Gunnar Cario, Hermann Einsele, Udo Holtick, Christian Koenecke, Annette Künkele, Roland Meisel, Fabian Mueller, Ingo Müller, Olaf Penack, Eva Rettinger, Martin G. Sauer, Paul-Gerhardt Schlegel, Jan Soerensen, Arend von Stackelberg, Tobias Feuchtinger, Andrea Jarisch
Journal: Blood
Blood (2022) 140 (Supplement 1): 10407–10409.
https://doi.org/10.1182/blood-2022-156775
Published: 2022
Journal Articles

Registry Data Indicate a Meaningful Chance for Successful Pregnancies after Allogeneic Stem Cell Transplantation: Results from the German Stem Cell Transplant Registry (DRST)

Katja Sockel, Sandra Frank, Annika Neu, Markus Ditschkowski, Inken Hilgendorf, Mareen Goeckenjan, Friedrich Stoelzel, Jan Moritz Middeke, Nicolaus Kröger, Francis A. Ayuk, Matthias Eder, Wolfgang Bethge, Jürgen Finke, Hartmut Bertz, Guido Kobbe, Martin Kaufmann, Uwe Platzbecker, David Beverungen, Christoph Schmid, Malte von Bonin, Katharina Egger-Heidrich, Lisa Heberling, Karolin Trautmann-Grill, Raphael Teipel, Gesine Bug, Johanna Tischer, Alessia Fraccaroli, Barbara Holler, Daniel Wolff, Thomas Luft, Wolf Roesler, Kerstin Schäfer-Eckart, Sabine Dressler, Christof Scheid, Udo Holtick, Stefan Klein, Igor Wolfgang Blau, Andreas Burchert, Gerald Wulf, Justin Hasenkamp, Rainer Schwerdtfeger, Stephan Kaun, Christoph Wittke, Friederike Wortmann, Helga Neidlinger, Martin Bornhaeuser, Johannes Schetelig, on Behalf of the German Cooperative Transplant Study Group
Journal: Blood
Blood (2022) 140 (Supplement 1): 10563–10565.
https://doi.org/10.1182/blood-2022-162673
Published: 2022
Journal Articles

Characterization and T-Cell Repertoire of MB-CART2019.1 (Zamtocabtagene autoleucel) - Data from the Phase I Trial in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Tatjana Holzer, Stefanie Biedermann, Inga Herfort, Birte Friedrichs, Silke Holtkamp, Linda Hanssens, Mario Assenmacher, Ulf Bethke, Dina Schneider, Stefan Miltenyi, Toon Overstijns, Christoph Schmid, Francis A. Ayuk, Christoph Scheid, Anja Jühling, Udo Holtick, Philipp Gödel, Peter Borchmann, Iris Bürger
Journal: Blood
Blood (2022) 140 (Supplement 1): 4581–4583.
https://doi.org/10.1182/blood-2022-164597
Published: 2022
Journal Articles

The Potential of E-Health in Patients after Allogeneic Stem Cell Transplantation

Friederike Schmitz, Charlotte Neuerburg, Martin Schumacher, Udo Holtick, Edgar Jost, Guido Kobbe, Ben-Niklas Bärmann, Marie-Therese Schmitz, Matthias Schmid, Peter Brossart, Martin Holderried, Tobias A.W. Holderried
Journal: Blood
Blood (2022) 140 (Supplement 1): 7966–7967.
https://doi.org/10.1182/blood-2022-160320
Published: 2022
Journal Articles

A Phase I Dose Finding Trial of MB-CART20.1 in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Nadine Kutsch, Philipp Gödel, Udo Holtick, Anja Lohneis, Vladan Vucinic, Florentine Pia Altefrohne, Christin Schubert, Sandra Karitzky, Linda Hanssens, Mario Assenmacher, Iris Bürger, Murat Aktas, Peter Borchmann
Journal: Blood
Blood (2022) 140 (Supplement 1): 12980–12981.
https://doi.org/10.1182/blood-2022-168730
Published: 2022
Journal Articles

Inferior Outcomes of EU Vs. US Patients with Relapsed/Refractory Large B-Cell Lymphoma after CD19 CAR T-Cell Therapy Are Associated with Differences in Tumor Burden, Systemic Inflammation, Bridging Therapy Utilization and CAR-T Product Selection

Veit L Buecklein, Ariel Perez-Perez, Kai Rejeski, Gloria Iacoboni, Vindi Jurinovic, Udo Holtick, Olaf Penack, Soraya Kharboutli, Viktoria Blumenberg, Josephine Ackermann, Lisa Frölich, Grace Johnson, Kedar Patel, Brian Arciola, Christian Schmidt, Omar Albanyan, Philipp Gödel, Eva Hoster, Lars Bullinger, Andreas Mackensen, Frederick L. Locke, Michael von Bergwelt, Pere Barba, Michael D. Jain, Marion Subklewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 2411–2413.
https://doi.org/10.1182/blood-2022-165452
Published: 2022
Journal Articles

GLA/DRST real-world outcome analysis of CAR T-cell therapies for large B-cell lymphoma in Germany

Clinical Trials & Observations
Wolfgang A. Bethge, Peter Martus, Michael Schmitt, Udo Holtick, Marion Subklewe, Bastian von Tresckow, Francis Ayuk, Eva Marie Wagner-Drouet, Gerald G. Wulf, Reinhard Marks, Olaf Penack, Ulf Schnetzke, Christian Koenecke, Malte von Bonin, Matthias Stelljes, Bertram Glass, Claudia D. Baldus, Vladan Vucinic, Dimitrios Mougiakakos, Max Topp, Matthias A. Fante, Roland Schroers, Lale Bayir, Peter Borchmann, Veit Buecklein, Justin Hasenkamp, Christine Hanoun, Simone Thomas, Dietrich W. Beelen, Claudia Lengerke, Nicolaus Kroeger, Peter Dreger
Journal: Blood
Blood (2022) 140 (4): 349–358.
https://doi.org/10.1182/blood.2021015209
Published: 2022
Includes: Supplemental data
Journal Articles

Real-World Experience of CPX-351 As First-Line Treatment in 188 Patients with Acute Myeloid Leukemia

Christina Rautenberg, Friedrich Stölzel, Christoph Röllig, Matthias Stelljes, Verena I Gaidzik, Michael Lauseker, Oliver Kriege, Mareike Verbeek, Julia M. Unglaub, Felicitas Thol, Stefan W. Krause, Mathias Haenel, Charlotte Neuerburg, Vladan Vucinic, Christian Jehn, Julia Severmann, Maxi Wass, Lars Fransecky, Jens Chemnitz, Udo Holtick, Kerstin Schäfer-Eckart, Josephine Schröder, Sabrina Kraus, William Hermann Krüger, Ulrich Kaiser, Sebastian Scholl, Lea Henning, Guido Kobbe, Rainer Haas, Nael Alakel, Maximilian Alexander Röhnert, Katja Sockel, Maher Hanoun, Uwe Platzbecker, Tobias A. W. Holderried, Anke Morgner, Michael Heuser, Tim Sauer, Katharina S. Goetze, Eva Maria Wagner, Konstanze Döhner, Hartmut Döhner, Christoph Schliemann, Johannes Schetelig, Martin Bornhäuser, Ulrich Germing, Thomas Schroeder, Moritz Moritz Middeke
Journal: Blood
Blood (2021) 138 (Supplement 1): 33.
https://doi.org/10.1182/blood-2021-153440
Published: 2021
Journal Articles

Motixafortide (BL-8040) and G-CSF Versus Placebo and G-CSF to Mobilize Hematopoietic Stem Cells for Autologous Stem Cell Transplantation in Patients with Multiple Myeloma: The Genesis Trial

Zachary D. Crees, Keith E. Stockerl-Goldstein, Sarah Larson, Árpád Illés, Giuseppe Milone, Massimo Martino, Patrick Stiff, Douglas W. Sborov, Denise L. Pereira, Ivana N. Micallef, Gemma Moreno Jiménez, Gábor Mikala, Maria liz paciello Coronel, Udo Holtick, John W. Hiemenz, Muzaffar H. Qazilbash, Nancy M. Hardy, Tahir Latif, Irene García-Cadenas, Abi Vainstein, Ella Sorani, Irit Gliko-Kabir, Inbal Goldstein, Shaul Kadosh, John F. DiPersio
Journal: Blood
Blood (2021) 138 (Supplement 1): 475.
https://doi.org/10.1182/blood-2021-144296
Published: 2021
Journal Articles

Hematopoietic Cell Transplantation of Higher CD34+ Cell Doses and Specific CD34+ Subsets Mobilized with Motixafortide and/or G-CSF Is Associated with Rapid Engraftment - a Post-Hoc Analysis of the Genesis Trial

Zachary D. Crees, Keith E. Stockerl-Goldstein, Michael Retting, Sarah M Larson, Arpad Illes, Giuseppe Milone, Massimo Martino, Patrick Stiff, Douglas W. Sborov, Denise L. Pereira, Ivana N. Micallef, Gemma Moreno Jiménez, Gábor Mikala, Maria Liz Paciello Coronel, Udo Holtick, John W. Hiemenz, Muzaffar H. Qazilbash, Nancy M. Hardy, Tahir Latif, Irene García-Cadenas, Ella Sorani, Liron Shemesh-Darvish, Abi Vainstein, Shaul Kadosh, John F. DiPersio
Journal: Blood
Blood (2021) 138 (Supplement 1): 2849.
https://doi.org/10.1182/blood-2021-146783
Published: 2021
Journal Articles

Late Non-Relapse Mortality (NRM) after Standard-of-Care (SOC) CAR-T Cell Therapy for Large B-Cell Lymphoma (LBCL): Frequency, Causes, and Risk Factors.a GLA/DRST Real World Analysis

Peter Dreger, Maria-Luisa Schubert, Udo Holtick, Marion Subklewe, von Tresckow Bastian, Francis A. Ayuk, Eva Maria Wagner, Gerald Wulf, Reinhard Marks, Olaf Penack, Ulf Schnetzke, Christian Koenecke, Malte Von Bonin, Matthias Stelljes, Bertram Glass, Claudia D. Baldus, Vladan Vucinic, Dimitrios Mougiakakos, Max Topp, Daniel Wolff, Roland Schroers, Peter Borchmann, Kai Rejeski, Christine Hanoun, Claudia Lengerke, Simone Thomas, Dietrich W. Beelen, Nicolaus Kröger, Wolfgang A Bethge
Journal: Blood
Blood (2021) 138 (Supplement 1): 1748.
https://doi.org/10.1182/blood-2021-151469
Published: 2021
Journal Articles

Standard of Care CAR-T Cell Therapy for Large B-Cell Lymphoma (LBCL): Does Bridging Efficacy Matter? a German GLA/DRST Real World Analysis

Wolfgang A Bethge, Peter Martus, Michael Schmitt, Udo Holtick, Peter Borchmann, Marion Subklewe, Kai Rejeski, Bastian von Tresckow, Francis A. Ayuk, Nicolaus Kroeger, Eva-Maria Wagner-Drouet, Gerald Wulf, Reinhard Marks, Olaf Penack, Ulf Schnetzke, Christian Koenecke, Malte Von Bonin, Matthias Stelljes, Bertram Glass, Claudia D. Baldus, Vladan Vucinic, Dimitrios Mougiakakos, Max Topp, Daniel Wolff, Roland Schroers, Simone Thomas, Dietrich W. Beelen, Claudia Lengerke, Peter Dreger
Journal: Blood
Blood (2021) 138 (Supplement 1): 3822.
https://doi.org/10.1182/blood-2021-146120
Published: 2021
Journal Articles

Treatment of MDS, AML and CMML Relapse after Allogeneic Blood Stem Cell Transplantation with Azacitidine, Lenalidomide and Donor Lymphocyte Infusions - Final Results of the Prospective Azalena-Trial (NCT02472691)

Thomas Schroeder, Matthias Stelljes, Maximilian Christopeit, Eva Schmidt, Christoph Scheid, Jan-Henrik Mikesch, Christina Rautenberg, Paul Jäger, Nadja Drusenheimer, Udo Holtick, Stefan Klein, Rudolf Trenschel, Rainer Haas, Ulrich Germing, Nicolaus Kröger, Guido Kobbe
Journal: Blood
Blood (2021) 138 (Supplement 1): 411.
https://doi.org/10.1182/blood-2021-153282
Published: 2021
Journal Articles

Polatuzumab Vedotin in Relapsed and Refractory (r/r) Large B-Cell Lymphoma (LBCL): Real-World Data of the German National Compassionate Use Program (CUP)

Nora Liebers, MD, Johannes Duell, MD, Daniel Nörenberg, MD, Eva Kaebisch, MD, Andrea Kerkhoff, MD, Fabian Acker, MD, Stephan Fuhrmann, MD, Corinna Leng, MD PhD, Manfred Welslau, MD, Jens Chemnitz, MD, Jan Moritz Middeke, MD, Thomas Weber, MD, Ralf Ulrich Trappe, MD, Roald Pfannes, MD, Ruediger Liersch, MD, Christian Spoer, MD, Niklas Gebauer, MD, Stefan Fuxius, MD, Léandra Caillé, Christiane Pott, MD PhD, Christian Koenecke, MD, Udo Holtick, Thomas Geer, MD, Ulrich Keller, MD, Rainer Claus, MD, Dimitrios Mougiakakos, MD, Stephanie Mayer, MD, Andreas Hüttmann, MD, Arne Trummer, MD, Gerald Wulf, MD, Uta Brunnberg, MD, Lars Bullinger, MD, Georg Hess, MD, Carsten Mueller-Tidow, MD, Bertram Glass, MD, Georg Lenz, Peter Dreger, MD, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-136539
Published: 2020
Journal Articles

Phase I Trial of MB-CART2019.1, a Novel CD20 and CD19 Targeting Tandem Chimeric Antigen Receptor, in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Peter Borchmann, Anja Jühling, Philipp Gödel, Hyatt Balke-Want, Christoph Schmid, Francis A. Ayuk, Silke Holtkamp, Liane Preussner, Gregor Zadoyan, Linda Hanssens, Andrew Kaiser, Marion Jurk, Iris Bürger, Dina Schneider, Boro Dropulic, Toon Overstijns, Christof Scheid, MD, Udo Holtick, Stefan Miltenyi, Michael Hallek
Journal: Blood
Blood (2020) 136 (Supplement 1): 48.
https://doi.org/10.1182/blood-2020-136067
Published: 2020