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Roland Fenk
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Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial

Marc S. Raab, Niels Weinhold, K. Martin Kortüm, Jan Krönke, Lilli Podola, Uta Bertsch, Jan H. Frenking, Julia Mersi, Stefanie Huhn, Michael Hundemer, Gunhild Mechtersheimer, Roland Fenk, Katja C. Weisel, Natalie Schub, Florian Bassermann, Monika Engelhardt, Raphael Teipel, Mathias Hänel, Hans Salwender, Bas D Koster, Elena Ershova, Caline Sakabedoyan, Isobel Barrott, Agnes Balogh, Sanjay Vara, Tobias Kampfenkel, Hartmut Goldschmidt, Hermann Einsele, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 493.
https://doi.org/10.1182/blood-2024-206003
Published: 2024
Journal Articles

Impact of Minimal Residual Disease on Progression-Free Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy in the Phase 3 GMMG-HD7 Trial

Elias K. Mai, Hans Salwender, Michael Hundemer, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Niels Weinhold, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc S. Raab, Martin Hoffmann, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 364.
https://doi.org/10.1182/blood-2024-194768
Published: 2024
Journal Articles

Quality of Life in the Multicenter, Randomized, Phase 3 GMMG-HD6 Trial Applying Elotuzumab, Lenalidomide, Bortezomib and Dexaemethason in Patients with Newly-Diagnosed Multiple Myeloma

Anna Fleischer, Elias K. Mai, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Markus Munder, Christine Hanoun, Igor Wolfgang Blau, Christoph Mann, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Marc S. Raab, Katja C. Weisel, Hans Salwender, Imad Maatouk, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 1963.
https://doi.org/10.1182/blood-2024-205230
Published: 2024
Journal Articles

Long-Term Follow-up Analysis of Progression-Free and Overall Survival in Newly Diagnosed Multiple Myeloma Patients from the GMMG Myeloma Registry Following the Randomized Phase III GMMG-HD6 Trial

Anne-Valérie Keller, Marina Hajiyianni, Eileen Kurre, Elias Karl Mai, Uta Bertsch, Axel Benner, Steffen Luntz, Marc-Steffen Raab, Britta Besemer, Christian Sebastian Michel, Roland Schroers, Roland Fenk, Hans Salwender, Igor Wolfgang Blau, Mathias Hänel, Christoph Mann, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 5140.
https://doi.org/10.1182/blood-2024-194188
Published: 2024
Journal Articles

Single Vs. Tandem Autologous Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Real-World Multi-Center Study from the German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)

Nora Grieb, Alexander Oeser, Maximilian Ferle, Franziska Hanke, Sarah Flossdorf, Sandra Sauer, Hartmut Goldschmidt, Carsten Müller-Tidow, Hans Salwender, Roland Fenk, Monika Engelhardt, Robert Zeiser, Vladan Vucinic, Georg-Nikolaus Franke, Igor Wolfgang Blau, Daniel Teschner, Hermann Einsele, Christoph Richard Kimmich, Miriam Kull, Britta Besemer, Nico Gagelmann, Nicolaus Kröger, Thomas Neumuth, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 708.
https://doi.org/10.1182/blood-2024-198638
Published: 2024
Journal Articles

Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy for Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Final Progression-Free Survival Analysis of Part 1 of an Open-Label, Multicenter, Randomized, Phase 3 Trial (GMMG-HD7)

Hartmut Goldschmidt, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Michael Hundemer, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc-Steffen Raab, Martin Hoffmann, Katja C. Weisel, Hans Salwender, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 769.
https://doi.org/10.1182/blood-2024-193308
Published: 2024
Journal Articles

Clonal Evolution of Lymphoid Malignancies Following the Mutagenic Impact of Radiotherapy

Benjamin Diamond, Dhanvantri Chahar, Michael D. Jain, Alexandra Maria Poos, Michael Durante, Bachisio Ziccheddu, Marcella Kaddoura, Marios Papadimitriou, Kylee H Maclachlan, Tomas Jelinek, Faith E Davies, Nicholas B Figura, Gareth Morgan, Elias K. Mai, Hartmut Goldschmidt, Katja C. Weisel, Roland Fenk, Saad Z. Usmani, Ola Landgren, Frederick Locke, Marc S. Raab, Jonathan H. Schatz, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (Supplement 1): 1607.
https://doi.org/10.1182/blood-2024-200927
Published: 2024
Journal Articles

Cilta-Cel Is Associated with Improved Outcomes and Distinct Cellular Dynamics Compared with Ide-Cel for Relapsed or Refractory Multiple Myeloma

Nico Gagelmann, Friedrich Stölzel, Roland Fenk, Tobias A.W. Holderried, Fabian Mueller, Natalia Tovar, Aina Oliver-Caldés, Kristin Rathje, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Bärmann, Francis A. Ayuk, Uwe Platzbecker, Anca Maria Albici, Natalie Schub, Friederike Schmitz, Cyrus Khandanpour, Marcel Teichert, Barbara Jeker, Nicolaus Kroeger, Bastian von Tresckow, Carlos Fernandez de Larrea, Thomas Pabst, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2024-211410
Published: 2024
Journal Articles

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma

Anthony M. Cirrincione, Alexandra M. Poos, Bachisio Ziccheddu, Marcella Kaddoura, Marc-Andrea Bärtsch, Kylee Maclachlan, Monika Chojnacka, Benjamin Diamond, Lukas John, Philipp Reichert, Stefanie Huhn, Patrick Blaney, Dylan Gagler, Karsten Rippe, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Faith Davies, Hartmut Goldschmidt, Roland Fenk, Katja C. Weisel, Elias K. Mai, Neha Korde, Gareth J. Morgan, Saad Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (7): 771–783.
https://doi.org/10.1182/blood.2024024299
Published: 2024
Includes: Supplemental data
Journal Articles

Revealing Novel Mechanisms Underlying Inactivation of Tumor Suppressor Genes on Duplicated Chromosomes in Multiple Myeloma

Anthony Cirrincione, Marcella Kaddoura, Alexandra Maria Poos, Bachisio Ziccheddu, Kylee H Maclachlan, Monika Chojnacka, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander Lesokhin, Faith E. Davies, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Elias K. Mai, Neha Korde, Gareth J. Morgan, Marc S. Raab, Saad Z Usmani, Ola Landgren, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2023) 142 (Supplement 1): 874.
https://doi.org/10.1182/blood-2023-186802
Published: 2023
Journal Articles

Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse

Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2023) 142 (Supplement 1): 782.
https://doi.org/10.1182/blood-2023-178835
Published: 2023
Journal Articles

The Temporal Evolution of Chromosome 1q Gain and Hyperdiploidy and Its Impact on Clinical Outcomes in Multiple Myeloma

Francesco Maura, Marcella Kaddoura, Alexandra Maria Poos, Anthony Cirrincione, Benjamin Diamond, Kylee H Maclachlan, Bachisio Ziccheddu, Elias K. Mai, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Gareth J. Morgan, Saad Z Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold
Journal: Blood
Blood (2023) 142 (Supplement 1): 638.
https://doi.org/10.1182/blood-2023-182267
Published: 2023
Journal Articles

Spatial Dissection of the Bone Marrow Microenvironment in Multiple Myeloma By High Dimensional Multiplex Tissue Imaging

Marc-Andrea Baertsch, Alexander Brobeil, John Hickey, Maximilian Haist, Alexandra Maria Poos, Guolan Lu, Wilson Kuswanto, Christian Schuerch, Harald Voehringer, Wolfgang Huber, Gunhild Mechtersheimer, Carsten Mueller-Tidow, Peter Schirmacher, Katja Weisel, Roland Fenk, Hartmut Goldschmidt, Yury Goltsev, Marc S. Raab, Niels Weinhold, Garry P. Nolan
Journal: Blood
Blood (2023) 142 (Supplement 1): 85.
https://doi.org/10.1182/blood-2023-189255
Published: 2023
Journal Articles

Immunological Subgroups Predicting Efficacy of Elotuzumab in Multiple Myeloma Patients: Insights from the GMMG-HD6 Clinical Trial

Gigi Nu Hoang Quy Ton, Katharina Kriegsmann, Mohamed H.S. Awwad, Axel Benner, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Andreas Neubauer, Niels Weinhold, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glätzer, Katja Weisel, Hans Salwender, Carsten Müller-Tidow, Marc S. Raab, Hartmut Goldschmidt, Elias K. Mai, Michael Hundemer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1991.
https://doi.org/10.1182/blood-2023-189169
Published: 2023
Journal Articles

Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome

Simon Steiger, Raphael Lutz, Nina Prokoph, Subarna Palit, Stephan M Tirier, Philipp Reichert, Anja Baumann, Nadine Hefner, Sabrina Schumacher, Dominik Vonficht, Florian Grünschläger, Alexandra M Poos, Lukas John, Laleh Haghverdi, Jan-Philipp Mallm, Elias K Mai, Mirco Friedrich, Katharina Kriegsmann, Mohamed H.S. Awwad, Anna Jauch, Uta Bertsch, Diana Tichy, Carsten Müller-Tidow, Roland Schroers, Hans Salwender, Britta Besemer, Roland Fenk, Katja Weisel, Hartmut Goldschmidt, Stefanie Huhn, Michael Hundemer, Karsten Rippe, Simon Haas, Niels Weinhold, Marc S Raab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2083–2085.
https://doi.org/10.1182/blood-2022-168685
Published: 2022
Journal Articles

Prediction of Early Death and Severe Infections during Novel Agent-Based Induction Therapy in Newly-Diagnosed Multiple Myeloma: An Intergroup Analysis from the German Speaking Myeloma Multicenter Group, the Dutch-Belgian Cooperative Trial Group for Hematology Oncology Foundation and the European Myeloma Network

Elias K Mai, Thomas Hielscher, Uta Bertsch, Hans Salwender, Sonja Zweegman, Markus Munder, Lucia Pantani, Peter Brossart, Meral Beksac, Igor Wolfgang Blau, Marc-Steffen Raab, Jan Dürig, Nicola Giesen, Britta Besemer, Roland Fenk, Peter Reimer, Bronno van der Holt, Mathias Haenel, Ivana v. Metzler, Ullrich Graeven, Mario Boccadoro, Christof Scheid, Meletios A. Dimopoulos, Katja Weisel, Michele Cavo, Pieter Sonneveld, Hartmut Goldschmidt
Journal: Blood
Blood (2021) 138 (Supplement 1): 3792.
https://doi.org/10.1182/blood-2021-145289
Published: 2021
Journal Articles

Elotuzumab in Combination with Lenalidomide, Bortezomib, Dexamethasone and Autologous Transplantation for Newly-Diagnosed Multiple Myeloma: Results from the Randomized Phase III GMMG-HD6 Trial

Hartmut Goldschmidt, Elias K Mai, Uta Bertsch, Britta Besemer, Mathias Haenel, Kaya Miah, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Andreas Neubauer, Christof Scheid, Roland Schroers, Ivana v. Metzler, Aneta Schieferdecker, Joerg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe M. Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glaetzer, Katja Weisel, Marc-Steffen Raab, Hans Salwender
Journal: Blood
Blood (2021) 138 (Supplement 1): 486.
https://doi.org/10.1182/blood-2021-147323
Published: 2021
Journal Articles

Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial

Hartmut Goldschmidt, Elias K Mai, Eva Nievergall, Roland Fenk, Uta Bertsch, Diana Tichy, Britta Besemer, Jan Dürig, Roland Schroers, Ivana v. Metzler, Mathias Haenel, Christoph Mann, Anne-Marie Asemissen, Bernhard Heilmeier, Stefanie Huhn, Katharina Kriegsmann, Niels Weinhold, Steffen P. Luntz, Tobias A. W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Cyrus Khandanpour, Wolfgang Knauf, Markus Munder, Thomas Geer, Hendrik Riesenberg, Joerg Thomalla, Martin Hoffmann, Marc-Steffen Raab, Hans Salwender, Katja Weisel
Journal: Blood
Blood (2021) 138 (Supplement 1): 463.
https://doi.org/10.1182/blood-2021-145097
Published: 2021
Journal Articles

Therapy-Related Myeloid Neoplasms Following Treatment for Multiple Myeloma : A Single-Center Analysis

Amelie Boquoi, MD, Soraya Magdalena Banahan, MD, Judith Strapatsas, MD, David Lopez y Niedenhoff, MD, Guido Kobbe, MD, Norbert Gattermann, MD, Ulrich Germing, MD, Rainer Haas, MD, Thomas Schroeder, MD, Roland Fenk, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4261.
https://doi.org/10.1182/blood-2019-122598
Published: 2019