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Yanming Zhang
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Journal Articles

Prospective study of patient-reported depression, and cognitive and functional impairment, and impact on survival and induction mortality in fit adults age ≥60 years receiving intensive chemotherapy (IC) for Acute Myeloid Leukemia (AML): Prospective geriatric assessment (GA) report from ECOG-ACRIN (EA) E2906 randomized study

Free
James Foran, Li Chen, Selina Luger, Zhuoxin Sun, Heidi Klepin, Catherine Lai, David Claxton, Hillard Lazarus, Daniel Arber, Jacob Rowe, Elisabeth Paietta, Janis Racevskis, Francine Garrett-Bakelman, Yanming Zhang, Jessica Altman, Aref Al-Kali, Hong Zheng, Keith Pratz, Kristen O'Dwyer, Edward Broun, Bayard Powell, John Godwin, Yishai Ofran, Efrat Dotan, Mark Litzow, Martin Tallman, Lynne Wagner
Journal: Blood
Blood (2025) 146 (Supplement 1): 882.
https://doi.org/10.1182/blood-2025-882
Published: 2025
Journal Articles

Bone marrow biopsy characteristics at nadir after intensive induction therapy do not predict outcomes in acute myeloid leukemia (AML): An analysis of ECOG-ACRIN clinical trials

Free
Douglas Tremblay, Li Chen, Zhuoxin Sun, Chezi Ganzel, Hugo Fernandez, James Foran, Daniel Arber, Hillard Lazarus, Yanming Zhang, Elisabeth Paietta, John Bennett, Jacob Rowe, Mark Litzow, Martin Tallman, Ehab Atallah, Selina Luger
Journal: Blood
Blood (2025) 146 (Supplement 1): 871.
https://doi.org/10.1182/blood-2025-871
Published: 2025
Journal Articles

Impact of DUSP22 and TP63 rearrangements in patients with ALK-negative ALCL treated with frontline BV-CH(E)P

Free
Zachary Epstein-Peterson, Nivetha Ganesan, Christina Poh, Ranjana Advani, Umut Aypar, Bryce Bowler, Ellie Casper, Tiffany Chang, Ahmet Dogan, Ozgur Can Eren, Tatyana Feldman, Natasha Galasso, Vaishali Gautam, Paola Ghione, Sarvarinder Gill, Kelly Hannigan, Jonathan Isenberg, Swami Iyer, Katie Ksanznak, Andrew Lytle, Jonathan Moreira, Alison Moskowitz, Ranjit Nair, Timothy Oh, Evelyn Orlando, Jia Ruan, Kerry Savage, Graham Slack, Robert Stuver, Jessie Xu, Austin Yeung, Jasmine Zain, Yanming Zhang, Steven Horwitz
Journal: Blood
Blood (2025) 146 (Supplement 1): 5410.
https://doi.org/10.1182/blood-2025-5410
Published: 2025
Journal Articles

粪便微生物移植在治疗类固醇难治性胃肠道移植物抗宿主病中的应用

Free
Xiaotian Yang, Ziyi Hao, Yan Wan, Bing Zhang, Li Wang, Sailan Huang, Hong Zhou, Huiran Jiang, Jin Hu, Jiangnan Liu, Yejun Si, Xingxia Zhang, Guoqiang Lin, Yanming Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 7776.
https://doi.org/10.1182/blood-2025-7776
Published: 2025
Journal Articles

The efficacy and safety of venetoclax and azacitidine combined with granulocyte-colony stimulating factor in the treatment of Acute Myeloid Leukemia

Free
Xiaotian Yang, Juan Chen, Ziyi Hao, Yejun Si, Xingxia Zhang, Guoqiang Lin, Bing Zhang, Li Wang, Yan Wan, Sailan Huang, Huiran Jiang, Yanming Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 6970.
https://doi.org/10.1182/blood-2025-6970
Published: 2025
Journal Articles

Inferior survival in black AML patients treated with intensive chemotherapy in ECOG-ACRIN clinical trials is independent of cytogenetic profiles

Free
Shella Saint Fleur-Lominy, Li Chen, Zhuoxin Sun, Francine Garrett-Bakelman, Mihir Shukla, Hugo Fernandez, James Foran, Larry Cripe, Hillard Lazarus, Peter Wiernik, Jacob Rowe, Martin Tallman, Mark Litzow, Yanming Zhang, Selina Luger, Irum Khan
Journal: Blood
Blood (2025) 146 (Supplement 1): 290.
https://doi.org/10.1182/blood-2025-290
Published: 2025
Journal Articles

Sparse whole genome sequencing and machine learning of AML genomes reveals novel, clinically relevant genetics.

Free
Timour Baslan, Pascal Belleau, Astrid Deschênes, Yanming Zhang, Zhuoxin Sun, Francine Garrett-Bakelman, Maria Kleppe, Elisabeth Paietta, Larry Cripe, Hugo Fernandez, Martin Tallman, Jacob Rowe, Hillard Lazarus, Ari Melnick, Mark Litzow, Ross Levine, Nevenka Dimitrova, Selina Luger, Alexander Krasnitz, Scott Lowe
Journal: Blood
Blood (2025) 146 (Supplement 1): 5263.
https://doi.org/10.1182/blood-2025-5263
Published: 2025
Journal Articles

Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR:ABL-1 negative acute lymphoblastic leukemia

Free
Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2025-5120
Published: 2025
Journal Articles

Structure-based virtual screening was performed to investigate the mechanism of action of dual-target inhibitors against FMS-like tyrosine kinase 3 (FLT3) and histone deacetylase 8 (HDAC8) in leukemia

Free
Xiaotian Yang, Ye Hong, Xingxia Zhang, Yejun Si, Guoqiang Lin, Yanming Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 6792.
https://doi.org/10.1182/blood-2025-6792
Published: 2025
Journal Articles

Impact of therapy delays on outcomes in adults with BCR::ABL1 negative b-lineage acute lymphoblastic leukemia (ALL) in the ECOG-ACRIN E1910 trial randomized to conventional chemotherapy +/- blinatumomab

Free
Bhavana Bhatnagar, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 1549.
https://doi.org/10.1182/blood-2025-1549
Published: 2025
Journal Articles

Characterization of gut microbiota and metabolomics in patients with Acute Myeloid Leukemia for journal publication requirements

Free
Ziyi Hao, Xiaotian Yang, Yejun Si, Xingxia Zhang, Guoqiang Lin, Yanming Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 7008.
https://doi.org/10.1182/blood-2025-7008
Published: 2025
Journal Articles

Characteristics and outcomes in Acute Myeloid Leukemia with Mecom rearrangement treated with hypomethylating agent plus venetoclax

Free
Leora Boussi, Elizabeth Corley, Andriy Derkach, Alex Ambinder, Somedeb Ball, Stephen Chung, Kateryna Fedorov, Ashwini Yenamandra, Emily F. Mason, Bao Duy An Hoang, Christopher Famulare, Meira Yisraeli Salman, Justin Wheat, Meghan Thompson, Sheng Cai, Eytan Stein, Yanming Zhang, Aaron Goldberg
Journal: Blood
Blood (2025) 146 (Supplement 1): 1616.
https://doi.org/10.1182/blood-2025-1616
Published: 2025
Journal Articles

Genomic determinants of treatment outcome and identification of a new genomic subset of adult acute lymphoblastic leukemia from the ECOG-ACRIN E1910 randomized phase III trial

Free
Xiaoming Zhong, Kathryn Roberts, Lindsey Montefiori, Zhuoxin Sun, Huimei Wei, Petri Polonen, Ti-Cheng Chang, Wenchao Zhang, Shaohua Lei, Evadnie Rampersaud, Yiping Fan, Gang Wu, Ryan Mattison, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Daniel Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Anjali Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Martin Tallman, Jun J. Yang, Elisabeth Paietta, Selina Luger, Mark Litzow, Charles Mullighan
Journal: Blood
Blood (2025) 146 (Supplement 1): 31.
https://doi.org/10.1182/blood-2025-31
Published: 2025
Journal Articles

Defining 2 biologically and clinically distinct groups in acute leukemia with a mixed phenotype

Available to Purchase
Pallavi Galera, Deepika Dilip, Andriy Derkach, Alexander Chan, Yanming Zhang, Sonali Persaud, Tanmay Mishra, Kyle Kramer, Mahak Kathpalia, Ying Liu, Christopher Famulare, Qi Gao, Douglas A. Mata, Maria Arcila, Mark B. Geyer, Eytan Stein, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Jacob Glass, Wenbin Xiao
Journal: Blood
Blood (2025) 145 (18): 2056–2069.
https://doi.org/10.1182/blood.2024026273
Published: 2025
Includes: Supplemental data
Journal Articles

Adult AML Patients with NUP98 Fusions Are Frequently Therapy-Related, and Are Associated with Monocytic Differentiation, Recurring Mutations in NRAS , DNMT3A and WT1 and Poor Outcome

Free
Jinjuan Yao, Umut Aypar, Shenon Sethi, Leora Boussi, Dory Londono, Purvil Sukhadia, Ellin Berman, Eytan M. Stein, Ahmet Dogan, Wenbin Xiao, Yanming Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1556.
https://doi.org/10.1182/blood-2024-203634
Published: 2024
Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Free
Nikolai A. Podoltsev, Zhuoxin Sun, Mark R. Litzow, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard M. Stone, Charles G. Mullighan, Martin S. Tallman, Selina Luger, Ryan J Mattison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4211.
https://doi.org/10.1182/blood-2024-207143
Published: 2024
Journal Articles

Sitagliptin for Prophylaxis of aGVHD in Alternative Donor Transplantations: Updated Results of 2 Years Follow-up of a Superiority, Randomized Controlled Phase III Trial

Free
Man Qiao, Suning Chen, Ying Wang, Shengli Xue, Xiaofei Yang, Depei Wu, Huiying Qiu, Yue Han, Yanming Zhang, Kourong Miao, Jihao Zhou, Xiaojin Wu, Miao Miao, Tao You, Xiao Ma, Haiping Dai
Journal: Blood
Blood (2024) 144 (Supplement 1): 4893.
https://doi.org/10.1182/blood-2024-207338
Published: 2024
Journal Articles

Sirolimus Plus Roxadustat in Patients with Pure Red Cell Aplasia: Results from a Prospective Multi-Center Clinical Trial

Free
Hong Wang, Qing Yuan Wang, Shan Liu, Yanming Zhang, Ke Ding, Xiaoli Li, Wenjing Jiao, Qian Zhang, Jing Cao, Weiyun Jiao, Miao Miao, Zefa Liu, Qiurong Liu, Guanqun Yang, Xiao Ma, Feng Chen, Jun Wang, Xiaohui Shangguan, Jinge Xu, Meiqing Lei, Hongxia Ma, Liansheng Zhang, Depei Wu, Limin Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3838.
https://doi.org/10.1182/blood-2024-201926
Published: 2024
Journal Articles

Genomic Complexity Correlates with the Degree of Marrow Independence of Malignant Plasma Cells in the Context of Extramedullary Disease

Free
Kylee H Maclachlan, Juan-Jose Garces, Tala Shekarkhand, Sridevi Rajeeve, Hamza Hashmi, Hani Hassoun, Malin Hultcrantz, Neha Korde, Carlyn Rose Tan, Sham Mailankody, Anish Simhal, David J. Chung, Gunjan L. Shah, Michael Scordo, Sergio Giralt, Alexandra Maria Poos, Lukas John, Yanming Zhang, Robert Cimera, Maria E. Arcila, Juan E Arango Ossa, Umesh Bhanot, Mala Jain, Tala Merghoub, Heather J. Landau, Alexander M. Lesokhin, Saad Z. Usmani, Niels Weinhold, Francesco Maura, Urvi A. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 248.
https://doi.org/10.1182/blood-2024-204341
Published: 2024
Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Free
Michaela Liedtke, Zhuoxin Sun, Mark R. Litzow, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry P. Erba, Richard M. Stone, Selina Luger, Charles G. Mullighan, Martin S. Tallman, Matthew J. Wieduwilt
Journal: Blood
Blood (2024) 144 (Supplement 1): 779.
https://doi.org/10.1182/blood-2024-207557
Published: 2024