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Meghan Thompson
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Journal Articles

Venetoclax retreatment of real-world patients with chronic lymphocytic leukemia previously treated with venetoclax-based regimens

Free
Mazyar Shadman, Meghan Thompson, Nilanjan Ghosh, Nnadozie Emechebe, Beenish Manzoor, Godwin Okoye, Neto Coulibaly, Wendy Sinai, Sophia Li, Rajesh Kamalakar, Brian Hill
Journal: Blood
Blood (2025) 146 (Supplement 1): 2108.
https://doi.org/10.1182/blood-2025-2108
Published: 2025
Journal Articles

Evaluation of ventoclax initiation prophylaxis and monitoring outcomes at each dose level and time point in patients with chronic lymphocytic leukemia: A real-world experience

Free
Christopher Jensen, Mazyar Shadman, Andres Chang, Nicole Lamanna, Beenish Manzoor, Chaitra Ujjani, Deborah Stephens, Wendy Sinai, Brian Hill, Jennifer Brown, Hande Tuncer, Matthew S Davids, Toby Eyre, Nicolas Martinez-Calle, Lori Leslie, Lindsey Roeker, Paul Barr, Nnadozie Emechebe, Alan Skarbnik, Bita Fakhri, Meghan Thompson, Joanna Rhodes, Isabelle Fleury, Frederick Lansigan, Robson Lima, Zhu Cui, Michael Coyle, Samin Houshyar, Laurie Pearson, Irina Pivneva, Talissa Watson, Annie Guerin, Nilanjan Ghosh
Journal: Blood
Blood (2025) 146 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2025-3885
Published: 2025
Journal Articles

Real-world changes in CLL treatment patterns following collaborative educational initiatives delivered in community settings

Free
Carmine Deluca, Michael Beyer, Marina Wanes, Catherine Coombs, Deborah Stephens, Lee Jamison, Javier Pinilla-Ibarz, Meghan Thompson, Nitin Jain, Brett Blum, Hejiang Wu, Renee Pearl
Journal: Blood
Blood (2025) 146 (Supplement 1): 6430.
https://doi.org/10.1182/blood-2025-6430
Published: 2025
Journal Articles

Integrating patient and clinician perspectives to advance R/R CLL care: Results of a multi-pronged global initiative

Free
Carmine Deluca, Michael Beyer, Marina Wanes, Jessica Massey, Meghan Thompson, Talha Munir, Wojciech Jurczak, Brian Koffman
Journal: Blood
Blood (2025) 146 (Supplement 1): 6428.
https://doi.org/10.1182/blood-2025-6428
Published: 2025
Journal Articles

Epcoritamab monotherapy demonstrates promising efficacy in patients with Richter transformation (RT): 2-year follow-up results from arm 2A of the phase 1b/2 EPCORE CLL-1 trial

Free
Arnon Kater, Ann Janssens, Herbert Eradat, Fritz Offner, Jose D. Sandoval-Sus, Mazyar Shadman, Christian Poulsen, Jacob Christensen, Meghan Thompson, Meijian Guan, Andrew J. Steele, Marcia Rios, Marie Holst Mørch, Toshihiko Oki, Rebecca Valentin, Mar Bellido, Barbara Eichhorst
Journal: Blood
Blood (2025) 146 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2025-1017
Published: 2025
Journal Articles

Updated efficacy and safety results of the Bruton tyrosine kinase (BTK) degrader BGB-16673 in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) from the ongoing phase 1 CaDAnCe-101 study

Free
Inhye Ahn, Ricardo Parrondo, Meghan Thompson, Annamaria Frustaci, John Allan, Paolo Ghia, Irina Mocanu, Damien Roos Weil, Constantine Tam, Stephan Stilgenbauer, Judith Trotman, Lydia Scarfo, Nicole Lamanna, Yanan Zhang, Linlin Xu, Kunthel By, Shannon Fabre, Daniel Persky, Amit Agarwal, John Seymour
Journal: Blood
Blood (2025) 146 (Supplement 1): 85.
https://doi.org/10.1182/blood-2025-85
Published: 2025
Journal Articles

CaDAnCe-304, a phase 3, open-label, randomized study to evaluate the safety and efficacy of Bruton tyrosine kinase degrader BGB-16673 compared with pirtobrutinib in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma

Free
Meghan Thompson, Constantine Tam, Kenneth Wu, Sheel Patel, Motohisa Takai, Patrick Phuong, Shelonitda Rose, Mark-David Levin, Talha Munir, Paolo Ghia, John Seymour
Journal: Blood
Blood (2025) 146 (Supplement 1): 5691.
https://doi.org/10.1182/blood-2025-5691
Published: 2025
Journal Articles

CaDAnCe-302, a phase 3, open-label, randomized study of BGB-16673 compared with idelalisib + rituximab (R), bendamustine + R, or venetoclax + R re-treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma previously exposed to both a BTK and BCL2 inhibitor

Free
Constantine Tam, John Seymour, Jiayi Shen, Jan Michel, Maryam Sarraf Yazdy, Patrick Brown, Shelonitda Rose, Motohisa Takai, Meghan Thompson, Mark-David Levin, Talha Munir, Paolo Ghia, Jeff Sharman
Journal: Blood
Blood (2025) 146 (Supplement 1): 8245.
https://doi.org/10.1182/blood-2025-8245
Published: 2025
Journal Articles

The outcomes of patients who are relapsed or refractory to menin inhibitors is poor with a limited overall survival

Free
Kuo-Kai Chin, Brian Ball, Yasmin Abaza, Jessica Altman, Rahul Thakur, Moiez Ali, Andriy Derkach, Mark Geyer, Aaron Goldberg, Tamanna Haque, Meghan Thompson, Jae Park, Martin Tallman, Sheng Cai, Eunice Wang, Ibrahim Aldoss, Eytan Stein
Journal: Blood
Blood (2025) 146 (Supplement 1): 39.
https://doi.org/10.1182/blood-2025-39
Published: 2025
Journal Articles

Molecular and structural basis of pan-resistance to BTK targeting therapies via BTK A428D mutation

Free
Quinlan Sievers, Hao Lu, Allison Cool, Stefan Gajewski, Tim Kong, Mark Noviski, Emel Ficici, Ratul Mukerji, James Iuliano, Jordan Ye, Mateo Sanchez Garcia de los Rios, Hugo Bousquet, Sarah Whelan, May Tan, Chris Phelps, Xiaoli Mi, Jahan Rahman, Samantha Sekeres, Erica Lamkin, Eduardo Bravo, Mark Ewalt, Anthony Mato, Lindsey Roeker, Justin Taylor, Meghan Thompson, Gwenn Hansen, Omar Abdel-Wahab
Journal: Blood
Blood (2025) 146 (Supplement 1): 2102.
https://doi.org/10.1182/blood-2025-2102
Published: 2025
Journal Articles

Superior real-world outcomes of lisocabtagene maraleucel in chronic lymphocytic leukemia

Free
Jennifer Huang, Jenna Voutsinas, Niranjan Khaire, Vincenzo Pizzuti, Leyla Shune, Matthew Lei, Rodrigo Fonseca, Mohammad Ammad Ud Din, Alan Skarbnik, Agrima Mian, Sushma Bharadwaj, Aseel Alsouqi, Bret Wankel, Graham Wehmeyer, Joseph Lukowski, Alexey Danilov, Tanya Siddiqi, Meghan Thompson, Michael Scordo, Stephanie Franco, Deborah Stephens, Chaitra Ujjani, Ryan Lynch, Jordan Gauthier, William Wierda, Paul Barr, Adam Kittai, Jonah Shulman, Matthew Lunning, Kerry Rogers, Bita Fakhri, Brian Hill, Javier Pinilla-Ibarz, Talal Hilal, Jacob Soumerai, Manali Kamdar, Qian Wu, Nitin Jain, Mazyar Shadman
Journal: Blood
Blood (2025) 146 (Supplement 1): 798.
https://doi.org/10.1182/blood-2025-798
Published: 2025
Journal Articles

Updated results from a Phase II study of minimal residual disease-guided venetoclax + obinutuzumab for the initial treatment of fit patients with chronic lymphocytic leukemia

Free
Meghan Thompson, Anthony Mato, Andrew Zelenetz, Jae Park, Mark Geyer, Andriy Derkach, David Nemirovsky, Deborah Stephens, Catherine Coombs, Prioty Islam, Christopher Jensen, Lorenzo Falchi, Lia Palomba, Anita Kumar, Gilles Salles, Eytan Stein, Jennifer Lue, Lauren Nogan, Bejal Kikani, Ryan Sutterby, Thu Quynh Nguyen, Alexandra Allen, Sumathy Sudhir, Gail Panton, Victoria Duffy, Dianna Tyznar, Jamila Brutus, Tenzin Nyima, Anmol Shah, Dhara Soni, Michael Silvestrone, Monica Shah, Miranda Harris, Megha Karnam, Claire Hutzler, Kevin David, Aaron Goldberg, Stephen Fleming, Giovanni Diaz, Habib Hamidi, Bita Fakhri, Lindsey Roeker
Journal: Blood
Blood (2025) 146 (Supplement 1): 3902.
https://doi.org/10.1182/blood-2025-3902
Published: 2025
Journal Articles

Preliminary efficacy and safety of the Bruton tyrosine kinase degrader BGB-16673 in patients with relapsed/refractory Richter transformation: Results from the ongoing phase 1 CaDAnCe-101 study

Free
Meghan Thompson, Annamaria Frustaci, John Seymour, John Allan, Paolo Ghia, Olivier Dumas, Franck Morschhauser, Martin Dreyling, Stephan Stilgenbauer, Inhye Ahn, Romain Guieze, Yanan Zhang, Linlin Xu, Kunthel By, Shannon Fabre, Daniel Persky, Amit Agarwal, Carlo Visco
Journal: Blood
Blood (2025) 146 (Supplement 1): 3895.
https://doi.org/10.1182/blood-2025-3895
Published: 2025
Journal Articles

Characteristics and outcomes in Acute Myeloid Leukemia with Mecom rearrangement treated with hypomethylating agent plus venetoclax

Free
Leora Boussi, Elizabeth Corley, Andriy Derkach, Alex Ambinder, Somedeb Ball, Stephen Chung, Kateryna Fedorov, Ashwini Yenamandra, Emily F. Mason, Bao Duy An Hoang, Christopher Famulare, Meira Yisraeli Salman, Justin Wheat, Meghan Thompson, Sheng Cai, Eytan Stein, Yanming Zhang, Aaron Goldberg
Journal: Blood
Blood (2025) 146 (Supplement 1): 1616.
https://doi.org/10.1182/blood-2025-1616
Published: 2025
Journal Articles

A Phase II multicenter study of minimal residual disease-guided, time-limited acalabrutinib + obinutuzumab for the initial treatment of chronic lymphocytic leukemia

Free
Meghan Thompson, Anthony Mato, Lia Palomba, Lori Leslie, Andriy Derkach, David Nemirovsky, Prioty Islam, Mark Geyer, Philip Caron, Aaron Goldberg, Anita Kumar, Alison Moskowitz, Jennifer Lue, Colette Owens, Gilles Salles, Eytan Stein, Raphael Steiner, Pallawi Torka, Lori Dahncke, Emily Ordona, Mashiyate Meem, Claire Hutzler, Miranda Harris, Monica Shah, Megha Karnam, Lauren Nogan, Caitlin Maloney, Anmol Shah, Tenzin Nyima, Colleen Dorsey, Kate Doyle, Jennifer Howgate-Klingaman, Jamila Brutus, Dianna Tyznar, Anna Lincke, Rick Wray, Tatyana Feldman, Andrew Zelenetz, Lindsey Roeker
Journal: Blood
Blood (2025) 146 (Supplement 1): 5676.
https://doi.org/10.1182/blood-2025-5676
Published: 2025
Journal Articles

Pirtobrutinib outcomes in second-line (2L) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) after first-line (1L) cBTKi therapy: A pooled analysis from the BRUIN LOXO-BTK-18001 and BRUIN CLL-321 studies

Free
Toby Eyre, Matthew S Davids, Jeff Sharman, Paul Barr, Catherine Coombs, Wojciech Jurczak, Koji Izutsu, Meghan Thompson, William Wierda, Ying (denise) Wang, Marisa Hill, Donald Tsai, Ching Ching Leow, Sarang Abhyankar, Paolo Ghia, Jennifer Woyach
Journal: Blood
Blood (2025) 146 (Supplement 1): 5670.
https://doi.org/10.1182/blood-2025-5670
Published: 2025